专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US5766956A Diode laser-based chemical and biological sensor 失效
标题翻译：二极管激光化学和生物传感器
公开(公告)号：US5766956A
公开(公告)日：1998-06-16
申请号：US862929
申请日：1997-05-27
申请人： Howard P. Groger , Russell J. Churchill , Shu-Fang Luo , K. Peter Lo
发明人： Howard P. Groger , Russell J. Churchill , Shu-Fang Luo , K. Peter Lo
IPC分类号： G01N21/39 , G01N21/77 , G01N21/63
CPC分类号： G01N21/7746 , G01N2021/391 , G01N2201/0612
摘要： A-compact, diode laser-based sensor has applications in biological and chemical analysis. Unlike existing optical waveguide-based sensors, no external coupling to external optical fibers or waveguides is required to perform optical chemical, immunological or nucleic acid-based assay or to detect the presence of toxic or otherwise important chemicals. The sensor includes a surface-sensitive diode laser having a substrate layer, an n-contact layer positioned on a bottom surface of the substrate, an n-clad layer overlying the top surface of the substrate, a first guide layer overlying the n-clad layer, a quantum well layer overlying the first guide layer, a second guide layer overlying the first quantum well layer, a p-clad layer overlying the second guided layer and a p-doped cap layer overlying the p-clad layer. A pair of electrodes separated by a surface-sensitive region is positioned on the cap layer. The surface active region includes an oxide layer grown on the thick cap layer and an absorbing or non-absorbing film deposited on the oxide layer. For internal reflection, inorganic material coatings are applied to end facets or Bragg reflectors are etched in the cap layer. Detectors are positioned proximate the diode laser for detecting changes in film thickness or refractive index, absorption or other optical properties resulting from film deposition, surface reactions such as immunological or ion-exchange reactions, or other detectable processes.
摘要翻译： A型紧凑型二极管激光传感器在生物和化学分析中有应用。与现有的基于光波导的传感器不同，不需要外部耦合到外部光纤或波导进行光学化学，免疫学或基于核酸的测定或检测有毒或其他重要化学物质的存在。该传感器包括具有衬底层，位于衬底底表面上的n接触层，覆盖在衬底顶表面上的n覆盖层的表面敏感二极管激光器，覆盖n覆层的第一引导层层，覆盖第一引导层的量子阱层，覆盖第一量子阱层的第二引导层，覆盖第二引导层的p覆盖层和覆盖p覆盖层的p掺杂覆盖层。由表面敏感区域隔开的一对电极位于盖层上。表面活性区域包括在厚盖层上生长的氧化物层和沉积在氧化物层上的吸收或非吸收膜。对于内反射，将无机材料涂层施加到端面，或者在盖层中蚀刻布拉格反射器。检测器位于二极管激光器附近，用于检测由膜沉积，表面反应如免疫或离子交换反应或其它可检测过程引起的膜厚度或折射率，吸收或其他光学性能的变化。

IPRDB

热门服务

关于我们

友情链接

联系方式