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1. 发明申请

WO02002505A2 COMPOUNDS TO TREAT ALZHEIMER'S DISEASE 审中-公开
标题翻译：用于治疗阿尔茨海默病的化合物
公开(公告)号：WO02002505A2
公开(公告)日：2002-01-10
申请号：PCT/US2001/020852
申请日：2001-06-29
IPC分类号： A61K9/06 , A61K9/08 , A61K9/10 , A61K9/19 , A61K9/20 , A61K9/48 , A61K9/70 , A61K31/166 , A61K31/27 , A61K31/336 , A61K47/48 , A61P7/04 , A61P9/00 , A61P9/10 , A61P25/16 , A61P25/28 , A61P43/00 , C07C215/28 , C07C233/78 , C07C235/84 , C07C239/16 , C07C239/20 , C07C243/22 , C07C243/28 , C07C243/34 , C07C271/16 , C07C271/18 , C07C275/24 , C07C311/03 , C07C311/05 , C07C311/08 , C07C311/13 , C07C311/16 , C07C311/37 , C07C317/44 , C07C323/60 , C07D211/60 , C07D215/12 , C07D277/04 , C07D295/13 , C07D303/36 , C07D307/52 , C07D307/54 , C07D333/24 , C07C215/00
CPC分类号： C07D295/13 , C07C215/28 , C07C233/78 , C07C235/84 , C07C239/20 , C07C243/22 , C07C243/28 , C07C271/16 , C07C271/18 , C07C275/24 , C07C311/03 , C07C311/05 , C07C311/08 , C07C311/13 , C07C311/16 , C07C311/37 , C07C317/44 , C07C323/60 , C07D211/60 , C07D215/12 , C07D277/04 , C07D303/36 , C07D307/52 , C07D307/54 , C07D333/24
摘要： The present invention is substituted amines of formula (X) useful in treating Alzheimer's disease and other similar diseases.
摘要翻译：本发明涉及对应于式（X）的取代的胺，其可用于治疗阿尔茨海默病或其他类似疾病。

2. 发明申请

WO2017006295A1 HYDROXY FORMAMIDE DERIVATIVES AND THEIR USE 审中-公开
标题翻译：羟基衍生物及其用途
公开(公告)号：WO2017006295A1
公开(公告)日：2017-01-12
申请号：PCT/IB2016/054119
申请日：2016-07-08
申请人： GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED
发明人： DOWDELL, Sarah E. , EIDAM, Hilary Schenck , ELBAN, Mark , FOX, Ryan Michael , HILFIKER, Mark A. , HOANG, Tram H. , KALLANDER, Lara S. , LAWHORN, Brian Griffin , MANNS, Sharada , PHILP, Joanne , WASHBURN, David G. , YE, Guosen
IPC分类号： C07D213/81 , C07D263/32 , C07C239/16 , A61K31/44 , A61K31/16 , A61P43/00
CPC分类号： C07D213/81 , C07C259/06 , C07C309/60 , C07C311/08 , C07C317/44 , C07C323/62 , C07C2601/08 , C07D263/32 , C07F5/025 , C07F9/588
摘要： Disclosed are compounds having the formula: (I) wherein R1, R2 and R3 are as defined herein, and methods of making and using the same, including use as inhibitors of BMP1, TLL1 and/or TLL2 and in treatment of diseases associated with BMP1, TLL1 and/or TLL2 activity.
摘要翻译：公开了具有下式的化合物：其中R 1，R 2和R 3如本文所定义，以及其制备和使用方法，包括用作BMP1，TLL1和/或TLL2的抑制剂和用于治疗与BMP1相关的疾病，TLL1和/或TLL2活性。

3. 发明申请

WO2008013334A1 DEFORMYLASE INHIBITOR, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION COMPRISING THE SAME 审中-公开
标题翻译：异构酶抑制剂，其制备方法和包含其的组合物
公开(公告)号：WO2008013334A1
公开(公告)日：2008-01-31
申请号：PCT/KR2006/003639
申请日：2006-09-13
申请人： PROMEDITECH INC. , LEE, Bong-Jin , LEE, Seung-Kyu , CHOI, Kwang-Hyun , LEE, Jong-Sun
发明人： LEE, Bong-Jin , LEE, Seung-Kyu , CHOI, Kwang-Hyun , LEE, Jong-Sun
IPC分类号： C07D213/78 , C07C239/16 , A61K31/495 , A61P31/04
CPC分类号： C07D213/81 , C07C259/06 , Y02P20/55
摘要： Provided are a novel compound useful for a deformylase inhibitor with excellent antibacterial activity or its pharmaceutically acceptable salt, a process for preparing the same, and an antibacterial composition including the same as an active ingredient. The deformylase inhibitor has a broad spectrum against bacteria, including bacteria with resistance to existing antibacterial agents.
摘要翻译：提供了可用于具有优异抗菌活性的变形酶抑制剂的新型化合物或其药学上可接受的盐，其制备方法和包含其的活性成分的抗菌组合物。变形酶抑制剂对细菌具有广谱性，包括对现有抗菌剂具有抗性的细菌。

4. 发明申请

WO2006051047A1 N-SUBSTITUTED IMIDES AS POLYMERIZATION INITIATORS 审中-公开
标题翻译：作为聚合引发剂的N-取代的咪唑
公开(公告)号：WO2006051047A1
公开(公告)日：2006-05-18
申请号：PCT/EP2005/055646
申请日：2005-10-31
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , NESVADBA, Peter , BENKHOFF, Johannes , BUGNON, Lucienne , POWELL, Karin , JUNG, Tunja
发明人： NESVADBA, Peter , BENKHOFF, Johannes , BUGNON, Lucienne , POWELL, Karin , JUNG, Tunja
IPC分类号： C08F4/00 , C07C239/16 , C07D209/48 , C07D207/40 , C07D221/14
CPC分类号： C07D207/404 , B33Y70/00 , C07D207/46 , C07D209/48 , C07D221/14 , C08F4/00
摘要： The invention relates to novel N-substituted imides and polymerizable compositions com¬ prising these N-substituted imides. The invention further relates to the use of N-substituted imides as polymerization initiators. The imides are compounds of the formula (I) and (II) wherein n is 1 or 2; m is 1 or 2; R 1 and R 2 are each, independently of one another, hydrogen, C 1 -C 18 alkyl, C 1 -C- 18 alkenyl C 6 -C 14 aryl, aralkyl, C 5 -C 12 cycloalkyl, each of which may be substituted by halogen, C 1 -C 4 -alkyl, hydroxy, C 1 -C 6 alkoxy, carbonyl, C 1 -C 6 alkoxycarbonyl; or R 1 and R 2 together with the adjacent -CO-N-CO- group may form a monocyclic, bicyclic or polycyclic ring, said ring having up to 50 non hydrogen atoms and wherein said ring may contain the structural element (formula III) more than once; R 3 if n is 1, is C 1 -C 18 alkyl, C 6 -C 14 aryl, aralkyl, C 5 -C 12 cycloalkyl, OR 10 or SR 11 , NR 12 R 13 ; wherein R 3 if n is 2, is C 2 -C 12 alkylene, C 6 -C 14 arylene, xylylene R 4 and R 5 , correspond to R 1 and R 2 ; R 6 if n is 1, is hydrogen, C 1 -C 18 alkyl, C 6 -C 14 aryl, aralkyl, C 5 -C 12 cycloalkyl, NR 14 R 15 ; wherein R 6 if n is 2, is C 2 -C 12 alkylene, C 6 -C 14 arylene, xylylene; R 7 is hydrogen, C 1 -C 18 alkyl, C 6 -C 14 aryl, aralkyl, C 5 -C 12 cycloalkyl, each of which may be substituted by halogen, C 1 -C 4 -alkyl, hydroxy, C 1 -C 6 alkoxy, carbonyl, C 1 -C 6 alkoxy- carbonyl; or R 7 and R 14 or R 7 and R 15 form together with the N-atom attached to R 7 a 5- 6 membered ring, optionally interrupted by -NH-, -N(C 1 -C 8 alkyl)-, -O- and/or S-atoms.
摘要翻译：本发明涉及新型N-取代的酰亚胺和可聚合的组合物，这些组合物包括这些N-取代的酰亚胺。本发明还涉及N-取代的酰亚胺作为聚合引发剂的用途。酰亚胺是式（I）和（II）的化合物，其中n为1或2; m为1或2; R 1和R 2各自彼此独立地为氢，C 1 -C 18烷基， C 1 -C 18 - 烯基C 6 -C 14芳基，芳烷基，C 5 - 其中每一个可被卤素取代，C 1 -C 4 - C 4 - 烷基，羟基，C 1 -C 12 - 羰基，C 1 -C 6烷氧基羰基，C 1 -C 6烷氧基羰基，C 1 -C 6烷氧基羰基，或R 1和R 2与相邻的-CO-N-CO-基团可以形成单环，双环或多环，所述环具有至多50个非氢并且其中所述环可以多次含有结构元素（式III）; 如果n为1，则R 3为C 1 -C 18烷基，C 6 -C 芳基，芳烷基，C 5 -C 12环烷基，OR 10或SR 11， NR _{12 - [R _{13 ; 如果n为2，其中R 3为C 2 -C 12亚烷基，C 6 -C > 14亚芳基，亚二甲苯基R 4和R 5对应于R 1和R 2， ; 如果n为1，则R 6为氢，C 1 -C 18烷基，C 6 -C 芳基，芳烷基，C 5 -C 12环烷基，NR 14 R 15， ; 如果n为2，其中R 6为C 12 -C 12亚烷基，C 6 -C 亚芳基，亚二甲苯; R 7是氢，C 1 -C 18烷基，C 6 -C 14烷基，C 1 -C 6烷基，芳基，芳烷基，C 5 -C 12环烷基，其各自可以被卤素取代，C 1 -C 12 - 4-烷基，羟基，C 1 -C 6烷氧基，羰基，C 1 -C 6烷基，C 1 -C 6烷基，烷氧基 - 羰基; 或R 7和R 14或R 7和R 15和与R连接的N-原子一起形成任选地被-NH-，-N（C 1 -C 8烷基） - ， - O-（C 1 -C 6）烷基取代的5-6元环， - 和/或S-原子。}}

5. 发明申请

WO0202518A3 COMPOUNDS TO TREAT ALZHEIMER'S DISEASE 审中-公开
标题翻译：化合物治疗阿尔茨海默病
公开(公告)号：WO0202518A3
公开(公告)日：2002-08-08
申请号：PCT/US0120856
申请日：2001-06-29
申请人： ELAN PHARM INC , UPJOHN CO
发明人： BECK JAMES P , GAILUNAS ANDREA , HOM ROY , JAGODZINSKA BARBARA , JOHN VARGHESE , MAILLAIRD MICHEL
IPC分类号： A61K9/06 , A61K9/08 , A61K9/10 , A61K9/19 , A61K9/20 , A61K9/48 , A61K9/70 , A61K31/166 , A61K31/27 , A61K31/336 , A61K47/48 , A61P7/04 , A61P9/00 , A61P9/10 , A61P25/16 , A61P25/28 , A61P43/00 , C07C215/28 , C07C233/78 , C07C235/84 , C07C239/16 , C07C239/20 , C07C243/22 , C07C243/28 , C07C243/34 , C07C271/16 , C07C271/18 , C07C275/24 , C07C311/03 , C07C311/05 , C07C311/08 , C07C311/13 , C07C311/16 , C07C311/37 , C07C317/44 , C07C323/60 , C07D211/60 , C07D215/12 , C07D277/04 , C07D295/13 , C07D303/36 , C07D307/52 , C07D307/54 , C07D333/24 , A61K31/165 , A61K31/17 , A61K31/18 , A61K31/33 , C07D295/12
CPC分类号： C07D295/13 , C07C215/28 , C07C233/78 , C07C235/84 , C07C239/20 , C07C243/22 , C07C243/28 , C07C271/16 , C07C271/18 , C07C275/24 , C07C311/03 , C07C311/05 , C07C311/08 , C07C311/13 , C07C311/16 , C07C311/37 , C07C317/44 , C07C323/60 , C07D211/60 , C07D215/12 , C07D277/04 , C07D303/36 , C07D307/52 , C07D307/54 , C07D333/24
摘要： The present invention is disubstituted amines of formula (I) and disbustituted amines of formula (II) useful in treating Alzheimer's disease and other similar diseases.
摘要翻译：本发明是用于治疗阿尔茨海默氏病和其他类似疾病的式（I）的二取代胺和式（II）的消除胺的胺。

6. 发明申请

WO0192218A2 NOVEL POLYAMINE ANALOGUES AS THERAPEUTIC AND DIAGNOSTIC AGENTS 审中-公开
标题翻译：新型聚氨酯类似物作为治疗和诊断试剂
公开(公告)号：WO0192218A2
公开(公告)日：2001-12-06
申请号：PCT/US0117795
申请日：2001-05-31
申请人： ORIDIGM CORP
发明人： VERMEULIN NICOLAAS M J , O'DAY CHRISTINE L , WEBB HEATHER K , BURNS MARK R , BERGSTROM DONALD E
IPC分类号： C07D233/90 , A61K31/16 , A61K31/165 , A61K31/166 , A61K31/17 , A61K31/18 , A61K31/185 , A61K31/197 , A61K31/198 , A61K31/27 , A61K31/277 , A61K31/341 , A61K31/381 , A61K31/401 , A61K31/405 , A61K31/415 , A61K31/42 , A61K31/427 , A61K31/433 , A61K31/44 , A61K31/4436 , A61K31/47 , A61K31/473 , A61K31/506 , A61K47/48 , A61P1/12 , A61P9/10 , A61P9/12 , A61P17/06 , A61P19/10 , A61P25/00 , A61P25/08 , A61P25/18 , A61P25/24 , A61P25/28 , A61P31/04 , A61P31/12 , A61P33/00 , A61P35/00 , A61P37/02 , A61P43/00 , C07C211/13 , C07C211/52 , C07C211/54 , C07C233/36 , C07C233/39 , C07C233/40 , C07C233/62 , C07C233/63 , C07C233/78 , C07C235/20 , C07C235/34 , C07C235/50 , C07C235/74 , C07C237/10 , C07C237/20 , C07C237/22 , C07C237/42 , C07C239/16 , C07C271/20 , C07C271/22 , C07C275/28 , C07C275/40 , C07C279/14 , C07C311/05 , C07C311/06 , C07C311/10 , C07C311/14 , C07C311/18 , C07C311/19 , C07C311/24 , C07C311/29 , C07C311/41 , C07C311/42 , C07C311/44 , C07C323/60 , C07C327/42 , C07D207/16 , C07D209/20 , C07D209/22 , C07D213/81 , C07D213/82 , C07D215/36 , C07D215/52 , C07D219/04 , C07D231/14 , C07D233/84 , C07D261/18 , C07D285/14 , C07D285/22 , C07D307/68 , C07D307/91 , C07D333/24 , C07D333/34 , C07D333/38 , C07D401/04 , C07D409/04 , C07D409/12 , C07D417/04 , C07F9/645 , G01N33/53 , C07C311/00
CPC分类号： C07D213/82 , A61K47/50 , C07C211/13 , C07C211/52 , C07C211/54 , C07C233/36 , C07C233/39 , C07C233/40 , C07C233/62 , C07C233/78 , C07C235/20 , C07C235/34 , C07C235/50 , C07C235/74 , C07C237/10 , C07C237/20 , C07C237/22 , C07C237/42 , C07C239/16 , C07C271/20 , C07C271/22 , C07C275/28 , C07C275/40 , C07C279/14 , C07C311/05 , C07C311/06 , C07C311/10 , C07C311/18 , C07C311/19 , C07C311/24 , C07C311/29 , C07C311/41 , C07C311/42 , C07C323/60 , C07C327/42 , C07C2601/02 , C07C2601/14 , C07C2601/16 , C07C2602/42 , C07C2603/24 , C07C2603/26 , C07C2603/40 , C07C2603/42 , C07C2603/50 , C07C2603/74 , C07D207/16 , C07D209/20 , C07D209/22 , C07D213/81 , C07D215/36 , C07D215/52 , C07D219/04 , C07D231/14 , C07D233/84 , C07D261/18 , C07D285/14 , C07D285/22 , C07D307/68 , C07D307/91 , C07D333/24 , C07D333/34 , C07D333/38 , C07D401/04 , C07D409/04 , C07D409/12 , C07D417/04 , C07F9/645 , G01N33/5308
摘要： Novel "bispolyamine" inhibitor compounds of polyamine transport are disclosed. These compounds are useful pharmaceutical agents for treating diseases where it is desired to inhibit polyamine transport or other polyamine binding proteins, for example cancer and post-angioplasty injury. These compounds display desirable activities both for diagnostic and research assays and therapy.
摘要翻译：公开了新型“双聚胺”抑制剂多胺转运剂化合物。这些化合物是治疗需要抑制多胺转运或其它多胺结合蛋白（例如癌症和血管成形术后损伤）的疾病的有用药物。这些化合物显示出用于诊断和研究测定和治疗的所需活性。

7. 发明申请

WO9207860A3 TECHNETIUM-99M COMPLEXES FOR USE AS RADIOPHARMACEUTICALS 审中-公开
标题翻译： TECHNETIUM-99M复合物作为无机物使用
公开(公告)号：WO9207860A3
公开(公告)日：1992-09-03
申请号：PCT/US9107908
申请日：1991-10-25
申请人： MALLINCKRODT MEDICAL INC
发明人： NOSCO DENNIS L
IPC分类号： A61K51/00 , A61K51/04 , C07C49/92 , C07C239/08 , C07C337/08 , C07F13/00 , C07C59/00 , C07C239/16 , C07C239/20
CPC分类号： C07F13/005 , A61K51/0478 , A61K2123/00 , C07C49/92 , C07C239/08 , C07C337/08
摘要： The present invention relates to novel technetium-99m complexes and to methods of preparing the complexes. The present invention further relates to a radiopharmaceutical composition comprising the complexes, to the use of the compositions for examining the renal function, and to a kit for preparing such compositions.

8. 发明申请

WO2013049280A3 SPHINGOSINE ANALOGS, COMPOSITIONS, AND METHODS RELATED THERETO 审中-公开
标题翻译： SPHINGOSINE类似物，组合物和与之相关的方法
公开(公告)号：WO2013049280A3
公开(公告)日：2013-05-30
申请号：PCT/US2012057448
申请日：2012-09-27
申请人： UNIV EMORY
发明人： LIOTTA DENNIS C , HOLT JASON J , NATCHUS MICHAEL G , GALINSKI MARY R , BAILLIE MARK T , MILLER ERIC J
IPC分类号： C07C215/08 , A61K31/133 , A61K31/15 , A61K31/164 , A61K31/40 , A61P31/04 , A61P31/10 , A61P31/12 , A61P33/00 , A61P33/02 , A61P33/06 , A61P35/00 , C07C215/10 , C07C215/24 , C07C215/44 , C07C225/06 , C07C235/08 , C07C239/16 , C07D207/08
CPC分类号： C07D207/08 , A61K31/133 , A61K31/40 , A61K45/06 , C07B2200/07 , C07C215/10 , C07C215/24 , C07C215/42 , C07C225/06 , C07C233/18 , C07C251/38 , C07C2601/02 , A61K2300/00
摘要： The disclosure relates to compounds, pharmaceutical compositions, and methods of treating or preventing disease. In certain embodiments, the disclosure relates to methods of treating an infection or cancer comprising administering a pharmaceutical composition disclosed herein to a subject in need thereof. In a typical embodiment, one administers a pharmaceutical composition comprising sphingosine or a sphingosine analog to a subject at risk for, exhibiting symptoms of, or diagnosed with a malaria infection.
摘要翻译：本公开涉及化合物，药物组合物以及治疗或预防疾病的方法。在某些实施方案中，本公开涉及治疗感染或癌症的方法，包括向有需要的受试者施用本文公开的药物组合物。在一个典型的实施方案中，一种药物组合物将包含鞘氨醇或鞘氨醇类似物的药物组合物施用于患有疟疾感染症状或被诊断患有疟疾感染风险的受试者。

9. 发明申请

WO2007010514A3 COMPOUNDS AND THEIR SALTS SPECIFIC TO THE PPAR RECEPTORS AND THE EGF RECEPTORS AND THEIR USE IN THE MEDICAL FIELD 审中-公开
标题翻译：化合物及其对PPAR受体和EGF受体的特异性及其在医学领域的应用
公开(公告)号：WO2007010514A3
公开(公告)日：2007-03-29
申请号：PCT/IE2006000076
申请日：2006-07-24
申请人： GIULIANI INT LTD , NACCARI GIANCARLO , BARONI SERGIO
发明人： NACCARI GIANCARLO , BARONI SERGIO
IPC分类号： C07C239/16 , A61K31/136 , A61K31/343 , A61K31/357 , A61P35/00 , C07C229/64 , C07D307/79 , C07D319/08
CPC分类号： C07D307/79 , C07C229/64 , C07C233/54 , C07C259/10 , C07D319/08
摘要： Therefore the present invention relates specifically to the compounds of general formula (I), in which R 1 and R 2 , which may be identical or different, are selected from the group comprising H , -C n H 2n-1 , a linear or branched alkyl group having from 1 to 6 carbon atoms, or together form an aromatic or aliphatic ring with 5 or 6 atoms; R 3 is selected from -CO-CH 3 , -NHOH, -OH, -OR 6 in which R 6 is a linear or branched alkyl group having from 1 to 6 carbon atoms; R 4 is selected from H, a linear or branched alkyl group having from 1 to 6 carbon atoms, phenyl, benzyl, -CF 3 or -CF 2 CF 3 , vinyl or allyl; R 5 , R 7 , R 8 are hydrogen atoms; or R 3 and R 4 , R 4 and R 5 , or R 7 and R 8 together form a ring, fused to the benzene, aromatic or aliphatic ring with 5 or 6 atoms comprising from 1 to 2 heteroatoms selected independently from the group comprising N, O. and use thereof in the medical field.
摘要翻译：因此，本发明具体涉及通式（I）的化合物，其中R 1和R 2可以相同或不同，选自含有1至6个碳原子的直链或支链烷基，或一起形成H 2，具有5或6个原子的芳族或脂族环; R 3选自-CO-CH 3，-NHOH，-OH，-OR 6，其中R 6， SUB>是具有1至6个碳原子的直链或支链烷基; R 4选自H，具有1至6个碳原子的直链或支链烷基，苯基，苄基，-CF 3或-CF 2， CF 3，乙烯基或烯丙基; R 5，R 7，R 8是氢原子; 或R 3和R 4，R 4和R 5或R 7或/或 >和R 8一起形成环，其与具有5或6个原子的苯，芳族或脂族环稠合，所述5或6个原子包含1至2个独立地选自N，O组的杂原子，并且其在医疗领域。

10. 发明申请

WO0202505A8 COMPOUNDS TO TREAT ALZHEIMER'S DISEASE 审中-公开
标题翻译：化合物治疗阿尔茨海默病
公开(公告)号：WO0202505A8
公开(公告)日：2003-11-20
申请号：PCT/US0120852
申请日：2001-06-29
申请人： ELAN PHARM INC
发明人： FANG LAWRENCE Y , HOM ROY , JOHN VARGHESE , MAILLAIRD MICHEL
IPC分类号： A61K9/06 , A61K9/08 , A61K9/10 , A61K9/19 , A61K9/20 , A61K9/48 , A61K9/70 , A61K31/166 , A61K31/27 , A61K31/336 , A61K47/48 , A61P7/04 , A61P9/00 , A61P9/10 , A61P25/16 , A61P25/28 , A61P43/00 , C07C215/28 , C07C233/78 , C07C235/84 , C07C239/16 , C07C239/20 , C07C243/22 , C07C243/28 , C07C243/34 , C07C271/16 , C07C271/18 , C07C275/24 , C07C311/03 , C07C311/05 , C07C311/08 , C07C311/13 , C07C311/16 , C07C311/37 , C07C317/44 , C07C323/60 , C07D211/60 , C07D215/12 , C07D277/04 , C07D295/13 , C07D303/36 , C07D307/52 , C07D307/54 , C07D333/24 , A61K31/165
CPC分类号： C07D295/13 , C07C215/28 , C07C233/78 , C07C235/84 , C07C239/20 , C07C243/22 , C07C243/28 , C07C271/16 , C07C271/18 , C07C275/24 , C07C311/03 , C07C311/05 , C07C311/08 , C07C311/13 , C07C311/16 , C07C311/37 , C07C317/44 , C07C323/60 , C07D211/60 , C07D215/12 , C07D277/04 , C07D303/36 , C07D307/52 , C07D307/54 , C07D333/24
摘要： The present invention is substituted amines of formula (X) useful in treating Alzheimer's disease and other similar diseases.
摘要翻译：本发明是用于治疗阿尔茨海默病和其他类似疾病的式（X）的取代的胺。

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