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    • 4. 发明申请
    • RUTHENIUM COMPLEXES USEFUL FOR CATALYZING METATHESIS REACTIONS
    • 钌配合物可用于催化分子间反应
    • WO2018087230A1
    • 2018-05-17
    • PCT/EP2017/078761
    • 2017-11-09
    • XIMO AG
    • EROS, GáborFRÁTER, Georg
    • C07C67/475C07F15/00C07F3/06C07C69/157C07C69/145B01J31/16C07B37/08
    • Compound of formula (4) or formula (5), wherein L is a neutral ligand, preferably a nitrogen-containing heterocyclic carbene (NHC) such as carbene containing at least two nitrogen atoms, a cyclic aminoalkyl carbene (CAAC) or a bicyclic aminoalkyl carbene (BICAAC); R 1 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 and R 11 are, independently, H, unbranched or branched C 1-20 alkyl, C 5-9 cycloalkyl, unbranched or branched C 1-20 alkoxy, optionally bearing one or more halogen atoms, respectively; or aryl, optionally substituted with one or more of unbranched or branched C 1-20 alkyl, C 5-9 cycloalkyl, unbranched or branched C 1-20 alkoxy, aryl, aryloxy, unbranched or branched C 1-20 alkylcarbonyl, arylcarbonyl, unbranched or branched C 1-20 alkoxycarbonyl, aryloxycarbonyl, heteroaryl, carboxyl, cyano, nitro, amido, aminosulfonyl, N-heteroarylsulfonyl, unbranched or branched C 1-20 alkylsulfonyl, arylsulfonyl, unbranched or branched C 1-20 alkylsulfinyl, arylsulfinyl, unbranched or branched C 1-20 alkylthio, arylthio, sulfonamide, halogen or N(R y )(R z ), wherein R y and R z are independently selected from H and C 1-20 alkyl: R 2 is H, unbranched or branched C 1-20 alkyl.
    • (4)或式(5)的化合物,其中L是中性配体,优选含氮杂环卡宾(NHC),例如含有至少两个氮原子的卡宾,环状氨基烷基 卡宾(CAAC)或双环氨基烷基卡宾(BICAAC); R 1,R 3,R 4,R 5,R 6,R 5,R 5,R 4,R 4, R 7,R 8,R 9,R 10和R 11是 独立地为H,直链或支链C 1-20烷基,C 5-9环烷基,非支链或支链C 1-20烷氧基, 任选分别带有一个或多个卤素原子; 或芳基,其任选被一个或多个非支链或支链C 1-20烷基,C 5-9环烷基,非支链或支链C 1-20烷基, 烷氧基,芳基,芳氧基,非支链或支链C 1-20烷基羰基,芳基羰基,非支链或支链C 1-20烷氧基羰基,芳氧基羰基,杂芳基,羧基,氰基 ,硝基,酰胺基,氨基磺酰基,N-杂芳基磺酰基,无支链或支链C 1-20烷基磺酰基,芳基磺酰基,无支链或支链C 1-20烷基亚磺酰基,芳基亚磺酰基,无支链或支链 C 1 -C 20烷硫基,芳硫基,磺酰胺,卤素或N(R y)(R z),其中R y, 和R Z独立地选自H和C 1-20烷基:R 2为H,非支链或支链C 1-20烷基。