专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2012157831A1 초고속 핵산의 정제방법 审中-公开
标题翻译：在超高速下净化核酸的方法
公开(公告)号：WO2012157831A1
公开(公告)日：2012-11-22
申请号：PCT/KR2011/010158
申请日：2011-12-27
申请人： (주)나노헬릭스 , 고민수 , 김영철 , 이시석
发明人： 고민수 , 김영철 , 이시석
IPC分类号： C12N15/10 , C12Q1/68 , G01N30/90
CPC分类号： C12N15/101 , C07H21/00 , C12N15/1003 , C12Q1/6806 , C12Q2523/308 , C12Q2527/125 , C12Q2531/113 , C12Q2565/137 , G01N30/90 , G01N2030/8827 , Y10T436/255
摘要： 본 발명은 초고속 핵산의 정제방법에 관한 것으로,상기 본 발명에 따른 초고속 핵산의 분리방법은 질병원의 진단이나 목적하는 유전자의 검출을 위하여 매우 유용한 방법으로，복잡하고 특수한 장비를 사용해야 하는 기존 핵산 분리 방법과 비교하여 신속하고 간편하게 질병원의 분자 진단에 사용될 수 있으며，숙련된 기술이 요구되지 않기 때문에 일반인들이 직접 질병원의 분석을 위한 핵산 분리가 가능하고, 더 나아가 병,의원또는 검진 센터의 방문을 통해서만 가능한 기존의 번거로움을 해결해 줄 수 있고 보다 더 신속하게 질병원을 분석할 수 있는 장점이 있다.
摘要翻译：本发明涉及一种以超高速纯化核酸的方法。用于纯化超高速分离核酸的Said方法可用于诊断疾病的原因或用于检测靶基因。该方法可以快速且简单地用于疾病原因的分子诊断，并且与使用复杂和特定设备分离核酸纯化的常规方法相比不需要熟练的技术。因此，普通人可以直接纯化分离的核酸来分析疾病原因的直接分析。此外，访问医院，医生办公室或诊断中心的不便可能会被消除，并且可能会迅速分析疾病的原因。

2. 发明申请

WO2012071472A2 MULTI-DIRECTIONAL MICROFLUIDIC DEVICES COMPRISING A PAN-CAPTURE BINDING REGION AND METHODS OF USING THE SAME 审中-公开
标题翻译：包含PAN捕获结合区域的多方向微流体装置及其使用方法
公开(公告)号：WO2012071472A2
公开(公告)日：2012-05-31
申请号：PCT/US2011/061959
申请日：2011-11-22
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , HERR, Amy E. , KIM, Dohyun
发明人： HERR, Amy E. , KIM, Dohyun
IPC分类号： G01N33/53 , G01N33/533 , G01N35/08 , G01N27/447
CPC分类号： B01L3/502753 , B01L3/502707 , B01L3/502715 , B01L3/50273 , B01L2200/0652 , B01L2300/0636 , B01L2300/0816 , B01L2300/0819 , B01L2300/0864 , B01L2300/0867 , B01L2400/0406 , B01L2400/0415 , B01L2400/0421 , B01L2400/0672 , G01N27/44791 , G01N33/54306 , G01N33/6803 , G01N33/6842 , G01N2550/00 , Y10T436/25375 , Y10T436/255
摘要： Microfluidic devices and methods for using the same are provided. Aspects of the invention include microfluidic devices that include a separation medium and a pan-capture binding medium. The microfluidic devices are configured to subject a sample to two or more directionally distinct electric fields. Also provided are methods of using the devices as well as systems and kits that include the devices. The devices, systems and methods find use in a variety of different applications, including diagnostic and validation assays.
摘要翻译：提供微流体装置及其使用方法。本发明的方面包括包括分离介质和泛捕获结合介质的微流体装置。微流体装置被配置为使样品经受两个或更多个定向不同的电场。还提供了使用设备的方法以及包括设备的系统和套件。设备，系统和方法可用于各种不同的应用，包括诊断和验证测定。

3. 发明申请

WO2011110734A1 APPARATUS FOR ANALYTE SENSING AND ASSOCIATED METHODS 审中-公开
标题翻译：分析仪感应及相关方法
公开(公告)号：WO2011110734A1
公开(公告)日：2011-09-15
申请号：PCT/FI2011/050050
申请日：2011-01-25
申请人： NOKIA CORPORATION , BAILEY, Marc
发明人： BAILEY, Marc
IPC分类号： G01N33/53 , G01N33/558 , G01N33/58
CPC分类号： G01N33/54306 , G01N33/54366 , Y10T436/25375 , Y10T436/255
摘要： An apparatus for the selective release of a bound species (707) based on the presence of an analyte (704), the apparatus comprising: a first (706) and second receptor species (709), the first receptor species (706) linked with a bound species (707) and configured to interact with an analyte (704) to form a first intermediate complex (711), the bound species (707) for causing increased porosity of a membrane (717) of an in-contact analyte sensor apparatus to correspondingly increase exposure of a sensing element of the analyte sensor apparatus to allow for production of a detectable electrical signal which can be used to sense the presence of the analyte (704), the second receptor species (709) for interacting with the first intermediate complex (711) to form a second intermediate complex (712); and a cleaving species, the cleaving species configured to interact with the second intermediate complex (709) to release the bound species (707) for use in sensing the presence of the analyte (704).
摘要翻译：一种用于基于分析物（704）的存在选择性释放结合物质（707）的装置，所述装置包括：第一受体（706）和第二受体物种（709），所述第一受体物种（706）与结合物质（707）并且被配置为与分析物（704）相互作用以形成第一中间复合物（711），所述结合物质（707）用于引起接触式分析物传感器装置的膜（717）的增加的孔隙率以相应地增加分析物传感器装置的感测元件的曝光，以允许产生可用于感测分析物（704）的存在的可检测电信号，用于与第一中间体相互作用的第二受体物质（709）复合物（711）以形成第二中间体复合物（712）; 和切割物种，所述切割物质配置为与第二中间复合物（709）相互作用以释放用于感测分析物（704）的存在的结合物质（707）。

4. 发明申请

WO2011091436A1 QUANTITATIVE ANALYSIS OF VITAMIN D3, VITAMIN D2, AND METABOLITES THEREOF 审中-公开
标题翻译：维生素D3，维生素D2及其代谢物的定量分析
公开(公告)号：WO2011091436A1
公开(公告)日：2011-07-28
申请号：PCT/US2011/022454
申请日：2011-01-25
申请人： DH TECHNOLOGIES DEVELOPMENT PTE. LTD. , DEY, Subhakar , PILLAI, Sasi , WILLIAMSON, Brian , PURKAYASTHA, Subhasish
发明人： DEY, Subhakar , PILLAI, Sasi , WILLIAMSON, Brian , PURKAYASTHA, Subhasish
IPC分类号： A01N45/00 , A61K31/59 , A61K31/41
CPC分类号： G01N33/82 , Y10T436/20 , Y10T436/200833 , Y10T436/203332 , Y10T436/24 , Y10T436/25 , Y10T436/25375 , Y10T436/255 , Y10T436/25875
摘要： Quantification of vitamin D2, vitamin D3, and the monohydroxy and diihydroxy metabolites of vitamin D2 and vitamin D3, can comprise labeling analytes with mass spectrometry (MS) tagging reagents and performing LC-MSMS analysis of the labeled analytes. The labeled analytes can include a labeled standard and can have distinct retention times on a reversed phase column, as well as distinct masses. Under high energy collisions, reporter groups can be generated. The intensity or the peak area detected for each reporter group can be used for quantitation. In some embodiments, a one-step tagging reagent is used that is a dienophile-containing, labeled Diels Alder reagent.
摘要翻译：维生素D 2，维生素D 3以及维生素D 2和维生素D 3的单羟基和二羟基代谢物的定量可以包括用质谱（MS）标记试剂标记分析物并且对标记物进行LC-MSMS分析分析物。标记的分析物可以包括标记的标准品，并且可以在反相色谱柱上具有不同的保留时间，以及不同的质量。在高能量碰撞下，可以生成记者组。每个报道基团检测到的强度或峰面积可用于定量。在一些实施方案中，使用一步标记试剂，其为含有亲二烯的标记Diels Alder试剂。

5. 发明申请

WO2007038660A3 DEVICE FOR CONTINUOUS REAL-TIME MONITORING AMBIENT AIR 审中-公开
标题翻译：连续实时监测环境空气的设备
公开(公告)号：WO2007038660A3
公开(公告)日：2011-05-26
申请号：PCT/US2006037796
申请日：2006-09-27
申请人： SCEPTOR IND INC
发明人： SWANK FREEMAN
IPC分类号： G01N1/24 , B01D47/02 , G01N35/10
CPC分类号： G01N1/2211 , G01N1/2273 , G01N2001/2217 , Y10T436/25375 , Y10T436/255 , Y10T436/25875
摘要： The present invention provides a device for continuous real-time monitoring of ambient air. The device includes a receptacle, a liquid supply, and a pressure balancing system. The receptacle includes a gas inlet slit located such that the gas inlet slit is covered by liquid within the receptacle during use. The pressure balancing portion of the present device includes communication between a point within the receptacle above the liquid level in the receptacle, as well as a liquid inlet portion at the lowermost end of the receptacle, and an air space above a liquid supply portion and the liquid supply portion itself, respectively.
摘要翻译：本发明提供一种用于连续实时监测环境空气的装置。该装置包括容器，液体供应和压力平衡系统。容器包括气体入口狭缝，其位于使用期间气体入口狭缝被容器内的液体覆盖。本装置的压力平衡部分包括在容器内的位于容器中的液位之上的点之间的连通，以及在容器的最下端的液体入口部分和液体供应部分上方的空气空间，液体供应部分本身。

6. 发明申请

WO2011028418A1 AN AUTOMATED METHOD AND SYSTEM FOR THE ANALYSIS OF TOTAL DIETARY FIBER 审中-公开
标题翻译：一种用于总膳食纤维分析的自动化方法和系统
公开(公告)号：WO2011028418A1
公开(公告)日：2011-03-10
申请号：PCT/US2010/045857
申请日：2010-08-18
申请人： ANKOM TECHNOLOGY CORPORATION , KOMAREK, Andrew R. , KOMAREK, Ronald J. , RITCHIE, Shawn W. , GIANNETTI, Richard
发明人： KOMAREK, Andrew R. , KOMAREK, Ronald J. , RITCHIE, Shawn W. , GIANNETTI, Richard
IPC分类号： A01N43/04 , A61K31/715
CPC分类号： B01L3/505 , A23L5/00 , B01D23/04 , B01L2200/0631 , B01L2300/0681 , B01L2300/087 , B01L2300/123 , B01L2300/18 , B01L2400/0487 , B01L2400/0655 , C12Q1/37 , C12Q1/40 , G01N1/4077 , G01N33/02 , G01N33/10 , G01N33/146 , G01N2001/4088 , G01N2400/10 , Y10T436/255
摘要： The invention consists of a method for determining Total Dietary Fiber (TDF) and its sub-fractions, Insoluble Dietary Fiber (IDF) and Soluble Dietary Fiber (SDF) in food and feed samples which utilizes flexible reaction / filtration containers that can be divided into one or more sections for capturing the IDF and SDF fractions separately or for capturing TDF in its entirety. Each container is fashioned as a bag that can be temporarily sealed in multiple locations to create multiple sections and is made of non-porous and porous material. Use of these containers eliminates the need for problematic transfers of mixtures from beaker to filter, and vastly improves the filtration process.
摘要翻译：本发明包括一种在食品和饲料样品中测定总膳食纤维（TDF）及其亚级分，不溶性膳食纤维（IDF）和可溶性膳食纤维（SDF）的方法，该方法利用灵活的反应/过滤容器，可分为一个或多个部分用于分别捕获IDF和SDF部分或用于完整捕获TDF。每个容器被形成为可以临时密封在多个位置以创建多个部分并由无孔和多孔材料制成的袋子。使用这些容器不需要从烧杯到过滤器的混合物有问题的转移，并大大改善了过滤过程。

7. 发明申请

WO2011020035A2 SORTING TWO-DIMENSIONAL NANOMATERIALS BY THICKNESS 审中-公开
标题翻译：通过厚度分配两维纳米颗粒
公开(公告)号：WO2011020035A2
公开(公告)日：2011-02-17
申请号：PCT/US2010/045493
申请日：2010-08-13
申请人： NORTHWESTERN UNIVERSITY , GREEN, Alexander, A. , HERSAM, Mark, C.
发明人： GREEN, Alexander, A. , HERSAM, Mark, C.
IPC分类号： B03D3/00
CPC分类号： C01G39/06 , B01D21/26 , B03D3/00 , B82Y30/00 , B82Y40/00 , C01B21/0648 , C01B32/19 , C01B32/194 , C01B32/196 , C01B32/20 , C01B2204/02 , C01B2204/04 , C01B2204/06 , C01B2204/28 , C01G29/006 , C01G41/00 , C01P2004/24 , C08G81/00 , C08L87/005 , Y10S977/845 , Y10T436/25375 , Y10T436/255
摘要： The present teachings provide, in part, methods of separating two-dimensional nanomaterials by atomic layer thickness. In certain embodiments, the present teachings provide methods of generating graphene nanomaterials having a controlled number of atomic layer(s).
摘要翻译：本教导部分地提供了通过原子层厚度分离二维纳米材料的方法。在某些实施方案中，本教导提供了产生具有受控数量的原子层的石墨烯纳米材料的方法。

8. 发明申请

WO2010096439A1 RESONANT SENSORS AND METHODS OF USE THEREOF FOR THE DETERMINATION OF ANALYTES 审中-公开
标题翻译：共振传感器及其使用方法用于确定分析仪
公开(公告)号：WO2010096439A1
公开(公告)日：2010-08-26
申请号：PCT/US2010/024416
申请日：2010-02-17
申请人： LEVERSENSE, LLC , LOVERICH, Jacob, J. , FRANK, Jeremy, E. , NAGY, Peter, A.
发明人： LOVERICH, Jacob, J. , FRANK, Jeremy, E. , NAGY, Peter, A.
IPC分类号： G01N33/53
CPC分类号： G01N29/022 , G01N29/036 , G01N29/2437 , G01N2291/012 , G01N2291/0255 , G01N2291/0256 , G01N2291/0427 , Y10T436/143333 , Y10T436/255
摘要： Resonant sensors, preferably having floating bilayer symmetry, and their methods of use is determining the presence, amount or binding kinetics of an analyte of interest in a test sample are disclosed. The test sample may be a liquid or gas.
摘要翻译：公开了共振传感器，优选具有浮双层对称性及其使用方法是确定测试样品中感兴趣分析物的存在，量或结合动力学。测试样品可以是液体或气体。

9. 发明申请

WO2010089138A1 DEVICES, SYSTEMS AND METHODS FOR SEPARATING MAGNETIC PARTICLES 审中-公开
标题翻译：用于分离磁性颗粒的装置，系统和方法
公开(公告)号：WO2010089138A1
公开(公告)日：2010-08-12
申请号：PCT/EP2010/000736
申请日：2010-02-05
申请人： CAPROTEC BIOANALYTICS GMBH , LENZ, Thomas
发明人： LENZ, Thomas
IPC分类号： G01N35/00 , B03C1/02
CPC分类号： B03C1/288 , B03C1/0332 , B03C2201/18 , B03C2201/22 , G01N35/0098 , Y10T436/255
摘要： A method and device for separating from samples magnetic particles that contain capture compounds on their surfaces. The device includes a magnet; a sheath having an orienting pin adapted to concentrate or direct a magnetic field of the magnet; and a magnetizable plate with a lid hole for receiving a vessel lid of a vessel, the magnetizable plate configured to receive the sheath and position the orienting pin over the vessel lid to separate molecules from a reaction mixture. It can be used to separate magnetic beads from a sample in a reaction vial. In an exemplary method, magnetic beads and a sample are mixed in a reaction vial. During the incubation, molecules from the sample attach to the magnetic particles. The magnetic beads with attached molecules are collected in the lids of the reaction vessel by a magnetic separator device while the reaction mixture (the supernatant) is removed. The separated magnetic particles attracted by a magnet of the device to the lid of the vessel carrying the molecules of interest through affinity-based attachment chemistry are released into a new vessel containing a solution by removal of the separator device without the need for pipettes or liquid handling devices.
摘要翻译：用于从样品中分离含有表面上的捕获化合物的磁性颗粒的方法和装置。该装置包括磁体; 具有适于集中或引导磁体的磁场的定向销的护套; 以及具有用于容纳容器的容器盖的盖孔的可磁化板，所述可磁化板被配置为接收护套并将定向销定位在容器盖上方以将反应混合物分离。它可以用于从反应瓶中的样品中分离出磁珠。在示例性方法中，磁珠和样品在反应小瓶中混合。在孵育期间，来自样品的分子附着到磁性颗粒上。将带有附着分子的磁珠通过磁选机器收集在反应容器的盖中，同时除去反应混合物（上清液）。通过基于亲和性的附着化学将装置的磁体吸引到携带有关分子的容器的盖子上的分离的磁性颗粒通过除去分离器装置而释放到含有溶液的新容器中，而不需要移液管或液体处理设备。

10. 发明申请

WO2010040347A3 MODULAR SYSTEM OF FUNCTIONAL UNITS FOR MIXING, PROCESSING AND/OR SEPARATING SAMPLES FOR USE IN BIOLOGICAL/MEDICAL RESEARCH AND FOR DIAGNOSTICS 审中-公开
标题翻译：对于混合，编辑和/或分离样品中使用生物/医学研究和用于诊断功能单元的模块化系统
公开(公告)号：WO2010040347A3
公开(公告)日：2010-06-17
申请号：PCT/DE2009001411
申请日：2009-10-06
申请人： UNIV LEIPZIG , HEINRICH JAN-MICHAEL , MOHR CHRISTOPH
发明人： HEINRICH JAN-MICHAEL , MOHR CHRISTOPH
IPC分类号： B01L3/00 , B01L99/00
CPC分类号： B01L3/502 , B01J2219/00011 , B01L3/0217 , B01L3/5082 , B01L3/5635 , B01L9/54 , B01L2200/028 , B01L2300/0681 , B01L2300/087 , B01L2400/049 , G01N1/38 , Y10T436/255
摘要： Basic steps of biological research and of diagnostics include mixing, physical and/or chemical reactions and separation. Particularly in research task-specific laboratory systems are required which are not commercially available due to small batch sizes and the specific problems to be faced. Because of the lack of such systems, researchers and diagnosticians have to improvise with already existing vessels, filters, centrifuges etc. to solve the problems. The aim of the invention is to devise a system of functional units which can be put together depending on the methodological type of problem. The system of functional units which can be freely combined consists of mixing cylinders (2), separation devices (3) and a flow-regulating connecting unit (5) which is preferably a vacuum unit and which is designed to be preferably interconnected in any order with any number of functional units via simple plug-in connections to give a self-contained sample processing system.
摘要翻译：混合，物理和/或化学反应和分离是生物研究和诊断的基本步骤。特别是，研究需要特定任务的实验室系统，这些系统由于小系列尺寸和特定问题而不能在市场上买到。在没有这些系统的情况下，有必要与现有的容器，过滤器，离心机等一起即兴解决问题。本发明的目的是提供一种取决于方法学任务的功能单元系统。可以放在一起。本发明的系统是自由地组合，功能单元中的，由混合气缸（2），分离器（3）和一个流量调节连接单元（5），优选形成为真空单元，其被设计为使得它优选通过以任意顺序与任何简单的连接许多功能单元连接到独立的样品处理系统。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式