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    • 6. 发明申请
    • NON-INVASIVE MONITORING OF INTRACRANIAL DYNAMIC EFFECTS AND BRAIN DENSITY FLUCTUATIONS
    • 非侵入性监测动脉内动态和脑密度变化
    • WO2005009244A1
    • 2005-02-03
    • PCT/CA2004/001401
    • 2004-07-26
    • HER MAJESTY THE QUEEN IN RIGHT OF CANADA asrepres ented by THE MINISTER OF NATIONAL DEFENSESTERGIOPOULOS, StergiosWROBEL, Miroslaw
    • STERGIOPOULOS, StergiosWROBEL, Miroslaw
    • A61B8/00
    • A61B5/031A61B5/4064A61B8/0808G01N29/0672G01N29/075G01N29/348G01N2291/02483G01S7/52036G01S15/8909
    • The present invention relates to a method and apparatus for non-invasive monitoring of brain density variations. At least two ultrasonic pulses having different frequencies are provided into the brain for transmission therethrough. The reflected ultrasonic pulses are then sensed and the sensed signal data are then processed for determining at least two phase differences between the phases of the at least two reflected ultrasonic pulses and the phases of the at least two provided ultrasonic pulses. A phase of at least a beat frequency is determined in dependence upon the at least two phase differences. Finally, data indicative of a brain density variation are determined based on the at least two phase differences and the at least a beat frequency. Repeating the process enables continuous monitoring of brain density variations. The method and apparatus for non-invasive monitoring of brain density variations is highly beneficial in clinical settings as well as during emergency and rescue operations by enabling early detection of brain density variations, which are directly related to intracranial pressure (ICP) changes; and provide diagnosis and assessment of head injuries, haemorrhage, stroke and variations of blood flow in the skull due to drug effects, changes in brain temperature and stress.
    • 本发明涉及用于非侵入性监测脑密度变化的方法和装置。 将至少两个具有不同频率的超声波脉冲提供到脑中以通过其传播。 然后感测反射的超声波脉冲,然后处理感测的信号数据,以确定至少两个反射的超声波脉冲的相位和至少两个提供的超声波脉冲的相位之间的至少两个相位差。 根据至少两个相位差确定至少拍频的相位。 最后,基于至少两个相位差和至少一个拍频来确定指示脑密度变化的数据。 重复该过程可以持续监测脑密度变化。 用于非侵入性监测脑密度变化的方法和装置在临床环境以及紧急和救援操作期间是非常有益的,通过能够早期检测与颅内压(ICP)变化直接相关的脑密度变化; 并提供由于药物作用,脑温度和压力变化引起的头部损伤,出血,中风和颅骨血流变化的诊断和评估。
    • 9. 发明申请
    • ULTRASONIC DENSITOMETER DEVICE AND METHOD
    • 超声波传感器装置及方法
    • WO1993025146A1
    • 1993-12-23
    • PCT/US1993005437
    • 1993-06-08
    • LUNAR CORPORATION
    • LUNAR CORPORATIONWIENER, Scott, A.DELUHERY, James, G.
    • A61B08/08
    • A61B8/4281A61B8/0875G01N29/07G01N29/11G01N29/28G01N29/348G01N2291/011G01N2291/015G01N2291/02483G01N2291/106
    • An ultrasound densitometer (100) is disclosed in which ultrasonic transducers (121) are located spaced apart in a water bath (103) into which the heel of a person may be inserted. The transit time of an ultrasonic pulse through the water and heel the attenuation of the pulse may be measured to evaluate the physical properties of the bone in the heel. A central controller (38, 160, 162) coordinates the ultrasonic measurement with the automatic filling and draining of the water bath to ensure hygienic and repeatable operation. The water may be preheated to reduce patient discomfort and to improve the consistency of the result. The delay of preheating is reduced by preheating water in a separate pre-fill chamber (132) during the previous scan. Gravity feed of the water reduces the complexity of the water handling and provides extremely quiet operation. A toe peg (110) in the water bath, which fits between the patient's toes, and a calf support (120) help to reduce patient motion during the measuring.
    • 公开了一种超声波密度计(100),其中超声波换能器(121)位于水浴(103)中间隔开的位置,可以插入人的脚跟。 可以测量超声波脉冲穿过水和脚跟的脉冲的衰减的传播时间,以评估脚后跟骨的物理性质。 中央控制器(38,160,162)通过水浴的自动灌装和排水来协调超声波测量,以确保卫生和可重复的操作。 可以预热水以减少患者的不适,并提高结果的一致性。 在先前的扫描期间,通过在单独的预填充室(132)中预热水来减少预热的延迟。 水的重力进料降低了水处理的复杂性,并提供了非常安静的操作。 位于患者脚趾之间的水浴中的脚趾钉(110)和小腿支撑件(120)有助于在测量期间减少患者运动。