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1. 发明申请

WO2019035093A1 A SIX DEGREES-OF-FREEDOM QUALITY ASSURANCE PHANTOM FOR RADIATION THERAPY LINEAR ACCELERATORS 审中-公开
公开(公告)号：WO2019035093A1
公开(公告)日：2019-02-21
申请号：PCT/IB2018/056247
申请日：2018-08-17
申请人： OHIO STATE INNOVATION FOUNDATION
发明人： WOODS, Kyle , AYAN, Ahmet , WOOLLARD, Jeffrey , GUPTA, Nilendu
IPC分类号： A61B6/04 , A61N5/10
CPC分类号： A61N5/1075 , A61B6/032 , A61B6/04 , A61B6/583 , A61N2005/1076
摘要： A three-dimensional phantom for providing displacement profiles for a CT table having 6 degrees of freedom includes a body having at a top face, a side face and an end face; the top face and the side face sharing a common edge; the top face and the end face sharing a common edge; and the side face and the end face sharing a common edge; wherein an angle formed by the top face and the end face is less than 90 degrees; the side face including a first isocenter mark and a first offset mark, wherein the first offset mark has an angle corresponding to the angle formed by the top face and the end face; and an isocenter marker at the isocenter of the body.

2. 发明申请

WO2018081420A1 METHODS FOR RADIATION THERAPY QUALITY ASSURANCE AND VERIFICATION 审中-公开
标题翻译：辐射治疗质量保证和验证方法
公开(公告)号：WO2018081420A1
公开(公告)日：2018-05-03
申请号：PCT/US2017/058524
申请日：2017-10-26
申请人： REFLEXION MEDICAL, INC.
发明人： OLCOTT, Peter Demetri , BASSALOW, Rostem , HARPER, Brent
IPC分类号： G12B13/00
CPC分类号： A61B6/037 , A61B6/583 , A61N5/1071 , A61N5/1075
摘要： This disclosure relates to phantoms for the calibration and quality assurance of radiation therapy systems, including biologically-guided radiation therapy systems, which deliver doses of radiation in response to real-time detected PET lines-of-response (LORs). The phantoms disclosed herein are modular phantoms that comprise a cylindrical housing with a plurality of disks stacked within the housing and a plurality of radiographic films. Some disks have a background region and a target region, where the rate of positron emissions of the target region is higher than for the background region. The disks may be arranged and rearranged within the housing to attain a desired target region shape.
摘要翻译：本公开涉及用于放射治疗系统的校准和质量保证的幻影，其包括生物引导放射治疗系统，其响应于实时检测到的PET响应线递送放射剂量（的LOR）。本文公开的模型是模块化模型，其包括具有堆叠在外壳内的多个圆盘的圆柱形外壳和多个射线照相胶片。一些磁盘具有背景区域和目标区域，其中目标区域的正电子发射率高于背景区域。盘可以被布置和重新布置在外壳内以获得期望的目标区域形状。

3. 发明申请

WO2017186522A1 A TREATMENT PLAN EVALUATION TOOL 审中-公开
标题翻译：治疗计划评估工具
公开(公告)号：WO2017186522A1
公开(公告)日：2017-11-02
申请号：PCT/EP2017/059076
申请日：2017-04-17
申请人： KONINKLIJKE PHILIPS N.V.
发明人： VAHALA, Erkki Tapani , WARNER, Lizette , GATTAMANENI, Kumar Raja
IPC分类号： G01R33/48 , A61N5/10 , G01R33/58 , G01R33/565
CPC分类号： A61N5/1075 , A61N5/1039 , A61N2005/1074 , G01R33/4812 , G01R33/56536 , G01R33/56563 , G01R33/58
摘要： It is an object of the invention to improve quality assurance when using MRI images for radiotherapy treatment planning. This object is achieved by a treatment plan evaluation tool A configured for calculating a quality indicator for a radiotherapy treatment plan. The radiotherapy treatment plan originates from a planning image, wherein the planning image is an MRI image acquired under a presence of a main magnetic field having a magnetic field inhomogeneity. The treatment plan evaluation tool is further configured to receive information about the magnetic field inhomogeneity and the treatment plan evaluation tool is further configured to calculate the quality indicator based on the information about the magnetic field homogeneity.
摘要翻译：当使用MRI图像进行放疗治疗计划时，本发明的目的是提高质量保证。该目的通过一种治疗计划评估工具A来实现，该工具A被配置用于计算放射治疗计划的质量指标。放射线治疗计划源自计划图像，其中计划图像是在存在具有磁场不均匀性的主磁场的情况下获取的MRI图像。治疗计划评估工具进一步被配置为接收关于磁场不均匀性的信息，并且治疗计划评估工具被进一步配置为基于关于磁场均匀性的信息来计算质量指标。

4. 发明申请

WO2017121795A1 VERFAHREN UND VORRICHTUNG ZUR ERMITTLUNG EINER RÄUMLICHEN CHARAKTERISTIK EINES PARTIKELSTRAHLS 审中-公开
标题翻译：确定粒子射线空间特性的方法和装置
公开(公告)号：WO2017121795A1
公开(公告)日：2017-07-20
申请号：PCT/EP2017/050560
申请日：2017-01-12
申请人： HELMHOLTZ-ZENTRUM DRESDEN - ROSSENDORF E.V.
发明人： HOFFMANN, Aswin , SPECK, Oliver
IPC分类号： G01R33/48 , A61N5/10
CPC分类号： A61N5/1048 , A61N5/1075 , A61N2005/1055 , A61N2005/1087 , G01R33/4808
摘要： Gemäß verschiedenen Ausführungsformen kann ein Verfahren (100) Folgendes aufweisen: Erzeugen (101) eines Magnetfeldes in einem Bestrahlungsbereich; Bestrahlen (103) des Bestrahlungsbereichs mittels eines Partikelstrahls, welcher spinpolarisierte Partikel aufweist; Erfassen (105) einer Anregung der spinpolarisierten Partikel, welche durch das Magnetfeld bewirkt wird; und Ermitteln (107) einer räumlichen Charakteristik des Partikelstrahls auf Grundlage der Anregung.
摘要翻译：
宝石。根据各种实施例，一种方法（100）可以包括：在照射区域中产生（101）磁场; 借助于具有自旋极化粒子的粒子束照射（103）照射区域; 检测（105）由磁场引起的自旋极化粒子的激发; 以及基于激励确定（107）粒子束的空间特性。

5. 发明申请

WO2016181140A1 RADIATION DOSAGE MONITORING SYSTEM 审中-公开
标题翻译：辐射剂量监测系统
公开(公告)号：WO2016181140A1
公开(公告)日：2016-11-17
申请号：PCT/GB2016/051350
申请日：2016-05-11
申请人： VISION RT LIMITED
发明人： HALE, Gideon , MEIR, Ivan , PAWLICKI, Todd , ALLEN, Martin
IPC分类号： A61N5/10 , A61B5/00 , G01T1/29 , G06T7/00
CPC分类号： A61N5/1071 , A61B5/0071 , A61N5/1048 , A61N5/1075 , A61N2005/1059 , A61N2005/1072 , A61N2005/1085 , G01T1/22 , G01T1/29 , G06T7/0012 , G06T7/85 , G06T15/04 , G06T2200/04 , G06T2207/30244 , H04N13/246
摘要： A radiation dosage monitoring system is disclosed comprising: a model generation module (58) operable to generate a 3D model of the surface of a portion of a patient (20) undergoing radiation treatment, an image detector (10) operable to detect Cherenkov radiation and any subsequent secondary and scattered radiation originating due to the initial Cherenkov radiation emitted from a surface of the patient (20) undergoing radiation treatment, a processing module (66) operable to determine estimations of radiation applied to the surface of a patient utilizing the images obtained by the image detector and the generated 3D model, and to utilize the determined estimations of radiation applied to the surface of the patient together with data indicative of the orientation of a radiation beam inducing emission of the Cherenkov radiation at a time when the radiation beam was applied to generate a 3D internal representation of the location of the portions of a patient irradiated by radiation resulting in the emission of the Cherenkov radiation.
摘要翻译：公开了一种辐射剂量监测系统，包括：模型生成模块（58），其可操作以产生经历放射治疗的患者（20）的一部分表面的3D模型;图像检测器（10），其可操作以检测切伦科夫辐射;以及由于从经历放射治疗的患者（20）的表面发射的初始切伦科夫辐射而产生的任何随后的次要和散射辐射，处理模块（66），其可操作以使用所获得的图像来确定施加到患者表面的辐射的估计通过图像检测器和所生成的3D模型，并且利用所确定的施加到患者表面的辐射的估计以及指示辐射束在辐射束为应用于产生由辐射解决方案照射的患者的部分的位置的3D内部表示在切伦科夫辐射的排放。

6. 发明申请

WO2016172352A1 RADIATION DETECTOR CALIBRATION 审中-公开
标题翻译：辐射探测器校准
公开(公告)号：WO2016172352A1
公开(公告)日：2016-10-27
申请号：PCT/US2016/028664
申请日：2016-04-21
申请人： SUN NUCLEAR CORPORATION
发明人： RAMEZANZADEH MOGHADAM, Amir , KOZELKA, Jakub
IPC分类号： A61N5/10
CPC分类号： A61N5/1075 , A61B5/055 , A61N5/1045 , A61N5/1049 , A61N5/1071 , A61N2005/1054
摘要： A computer program product, method, system and device that acquires, by a radiation detector, exit radiation measurement information during delivery of patient treatment. Patient anatomy information is also received and a radiation detector response calibration is determined utilizing at least the exit radiation measurement information, the patient anatomy information, and at least a portion of a radiation treatment plan.
摘要翻译：一种计算机程序产品，方法，系统和装置，其通过辐射检测器获得在传送患者治疗期间的出射辐射测量信息。还接收患者解剖信息，并且利用至少出射辐射测量信息，患者解剖信息和辐射治疗计划的至少一部分来确定放射线检测器响应校准。

7. 发明申请

WO2016103089A1 TRACKING QUALITY CONTROL FOR ELECTROMAGNETIC GUIDANCE 审中-公开
标题翻译：跟踪质量控制电磁指导
公开(公告)号：WO2016103089A1
公开(公告)日：2016-06-30
申请号：PCT/IB2015/059458
申请日：2015-12-09
申请人： KONINKLIJKE PHILIPS N.V.
发明人： DEHGHAN MARVAST, Ehsan , BHARAT, Shyam , TAHMASEBI MARAGHOOSH, Amir Mohammad , DALAL, Sandeep M. , KRUECKER, Jochen , KUNG, Cynthia Ming-fu , VENUGOPAL, Niranjan , RAVI, Ananth
IPC分类号： A61N5/10 , A61B5/06 , G01R29/08 , A61B10/02 , A61B17/00 , A61B34/20
CPC分类号： G01R29/0814 , A61B5/062 , A61B5/7221 , A61B10/02 , A61B34/20 , A61B2017/00725 , A61B2034/2051 , A61N5/1001 , A61N5/1075 , A61N2005/1051
摘要： An electromagnetic field quality assurance system employing an electromagnetic field generator (10) for emitting an electromagnetic field (12), and one or more quality assurance electromagnetic sensors (11, 21, 31, 41, 50) for sensing the emission of the electromagnetic field (12). The system further employs a quality assurance controller (74) for assessing a tracking quality of the electromagnetic field (12) derived from a monitoring of a sensed position of each quality assurance electromagnetic sensor (11, 21, 31, 41, 50) within a field-of-view of the electromagnetic field (12). The electromagnetic field generator (10), an ultrasound probe (20), an ultrasound stepper (30) and/or a patient table (40) may be equipped with the quality assurance electromagnetic sensor(s) (11, 21, 31, 41, 50).
摘要翻译：一种使用电磁场发生器（10）发射电磁场（12）的电磁场质量保证系统，以及用于感测电磁场发射的一个或多个质量保证电磁传感器（11,21,31,41,50）（12）。该系统进一步采用质量保证控制器（74），用于评估电磁场（12）的跟踪质量，该质量保证控制器（12）的监测来自每个质量保证电磁传感器（11,21,31,41,50）内的感测位置电磁场（12）的视场。电磁场发生器（10），超声波探头（20），超声波步进器（30）和/或患者台（40）可配备有质量保证电磁传感器（11,21,31,41 ，50）。

8. 发明申请

WO2016081622A1 ACTIVE WATER PHANTOM FOR THREE-DIMENSIONAL ION BEAM THERAPY QUALITY ASSURANCE 审中-公开
标题翻译：主要用于三维离子束治疗质量保证的水质
公开(公告)号：WO2016081622A1
公开(公告)日：2016-05-26
申请号：PCT/US2015/061376
申请日：2015-11-18
申请人： PHENIX MEDICAL LLC , BROOKHAVEN SCIENCE ASSOCIATES, LLC , VIGDOR, Steven E. , YEH, Minfang , JAFFE, David E.
发明人： VIGDOR, Steven E. , YEH, Minfang , JAFFE, David E.
IPC分类号： A61N5/00 , G01T1/16
CPC分类号： A61B6/4258 , A61B6/583 , A61N5/1075 , A61N2005/1076 , A61N2005/1087 , G01T1/169
摘要： An Active Water Phantom is designed to provide fast, accurate, high resolution, complete Quality Assurance of patient-specific treatment plans utilizing intensity-modulated Ion Beam Therapy, prior to their delivery to the patient. The detection medium is a tissue-equivalent water-based liquid scintillator material. A three-dimensional pattern of scintillation light, emitted upon ion beam irradiation, is reconstructed from three orthogonal two-dimensional light yield profiles, which are read out for each individual beam energy layer. The 3-D information has dose measurement accuracy 1-2% and spatial resolution 1-2 millimeters. The measurement sequence provides up to four orders of magnitude more data characterizing the treatment plan than currently commercially available alternatives, all in a time period no greater than that needed for actual delivery of the dose fraction to a patient. The system provides sophisticated control and readout of the cameras or photo-detectors, data archiving and analysis, simulation capabilities, and 3-D dose image reconstruction and visualization.
摘要翻译： Active Water Phantom旨在提供快速，准确，高分辨率，完整的质量保证，在使用强度调制离子束治疗之前，将患者特异性治疗计划交付给患者。检测介质是组织等效的水基液体闪烁体材料。从三个正交的二维光产生曲线重建离子束照射时发射的闪烁光的三维图案，其对于每个单独的光束能量层读出。 3-D信息的剂量测量精度为1-2％，空间分辨率为1-2毫米。测量序列提供比目前商业上可获得的替代物多达四个数量级的表征治疗计划的数据，所有这些数据在不大于向患者实际递送剂量分数所需的时间内。该系统提供复杂的摄像机或光电检测器的控制和读出，数据归档和分析，仿真功能和3-D剂量图像重建和可视化。

9. 发明申请

WO2016076598A1 방사선 치료기 및 방사선 치료기의 정도 관리 방법 审中-公开
标题翻译：辐射治疗装置和放射治疗装置的质量控制方法
公开(公告)号：WO2016076598A1
公开(公告)日：2016-05-19
申请号：PCT/KR2015/012044
申请日：2015-11-10
申请人： 사회복지법인 삼성생명공익재단
发明人： 주상규 , 홍채선 , 최두호
IPC分类号： A61N5/10
CPC分类号： A61N5/1075 , A61B6/08 , A61B6/587 , A61N5/10 , A61N5/1048 , A61N2005/1074
摘要： 본 발명의 일 실시예는 정도 관리가 수행되는 방사선 치료기에 있어서, 본체부; 상기 본체부의 일 측에 결합하며, 상기 본체부에 대해 적어도 일 방향으로 회전가능하도록 형성되는 갠트리; 상기 갠트리의 일 측에 형성되어 방사선을 조사하는 방사선 조사 헤드; 및 상기 방사선 조사 헤드의 일 측에 형성되어 상기 갠트리 또는 상기 방사선 조사 헤드의 회전 각도를 측정하고, 상기 측정된 회전 각도와 상기 방사선 치료기의 각도 지시계에 표시된 회전 각도를 비교하여, 상기 각도 지시계의 오차를 보정하는 수평 제어 모듈;을 포함하는 방사선 치료기를 개시한다.
摘要翻译：本发明的一个实施例提供了一种用于其进行质量控制的放射治疗装置，包括：主体部分; 龙门架，其联接到主体部分的一侧并构造成能够相对于主体部分在至少一个方向上旋转; 用于照射辐射的辐射照射头，所述辐射照射头形成在所述绅士的一侧; 以及水平度控制模块，用于测量绅士或辐射照射头的旋转角度，并将所测量的旋转角度与辐射治疗设备的角度指示器所指示的旋转角度进行比较，以校正角度指示器的误差，水平控制模块形成在放射线照射头的一侧。

10. 发明申请

WO2016075445A1 METHOD OF CALIBRATING A PATIENT MONITORING SYSTEM FOR USE WITH A RADIOTHERAPY TREATMENT APPARATUS 审中-公开
标题翻译：用放射治疗装置使用患者监护系统进行校准的方法
公开(公告)号：WO2016075445A1
公开(公告)日：2016-05-19
申请号：PCT/GB2015/053382
申请日：2015-11-09
申请人： VISION RT LIMITED
发明人： MEAD, Edward, William , MEIR, Ivan, Daniel
IPC分类号： G06T7/00 , A61N5/10
CPC分类号： A61N5/1075 , A61N5/1049 , A61N2005/1059 , G06T7/85 , G06T2207/30208 , H04N13/204
摘要： An image detector (10) of a patient monitoring system is used (S6-1) to obtain a set of calibration images of a calibration sheet (100) or other calibration object at various orientations and locations. These obtained calibration images are then stored and processed to calculate camera parameters defining the location and orientation of the image detector and parameters identifying internal characteristics of the image detector and the calculated parameters are stored (S6-2). Subsequently the patient monitoring system is re-calibrated by using (S6-3) the image detector (10) to obtain an additional image of a calibration sheet (100) or calibration object. The additional image and the stored camera parameters are then used to detect any apparent change in the internal characteristics of the image detector (10) (S6-4). If a change in the internal characteristics of an image detector (10) is detected, a further set of calibration images are obtained using the image detector (10) and the camera parameters for the image detector are recalculated using the further set of calibration images. If no change in the internal characteristics of an image detector is detected, the recalibration of the patient monitoring system is achieved by recalculating (s6-9) the camera parameters for the image detector using the stored set of calibration images and the additional image of the calibration object obtained by the image detector.
摘要翻译：使用患者监视系统的图像检测器（10）（S6-1）以在各种取向和位置获得校准片（100）或其他校准对象的一组校准图像。然后存储并处理这些获得的校准图像以计算定义图像检测器的位置和取向的相机参数，以及识别图像检测器的内部特性的参数并存储所计算的参数（S6-2）。随后，通过使用（S6-3）图像检测器（10）来获得校准片（100）或校准对象的附加图像来重新校准患者监视系统。然后使用附加图像和存储的照相机参数来检测图像检测器（10）的内部特性的任何明显变化（S6-4）。如果检测到图像检测器（10）的内部特性的改变，则使用图像检测器（10）获得另一组校准图像，并且使用另一组校准图像重新计算图像检测器的相机参数。如果没有检测到图像检测器的内部特性的改变，则通过使用所存储的校准图像集合和图像检测器的附加图像重新计算（s6-9）图像检测器的相机参数来实现患者监视系统的重新校准由图像检测器获得的校准对象。

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