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1. 发明申请

WO2016081622A1 ACTIVE WATER PHANTOM FOR THREE-DIMENSIONAL ION BEAM THERAPY QUALITY ASSURANCE 审中-公开
标题翻译：主要用于三维离子束治疗质量保证的水质
公开(公告)号：WO2016081622A1
公开(公告)日：2016-05-26
申请号：PCT/US2015/061376
申请日：2015-11-18
申请人： PHENIX MEDICAL LLC , BROOKHAVEN SCIENCE ASSOCIATES, LLC , VIGDOR, Steven E. , YEH, Minfang , JAFFE, David E.
发明人： VIGDOR, Steven E. , YEH, Minfang , JAFFE, David E.
IPC分类号： A61N5/00 , G01T1/16
CPC分类号： A61B6/4258 , A61B6/583 , A61N5/1075 , A61N2005/1076 , A61N2005/1087 , G01T1/169
摘要： An Active Water Phantom is designed to provide fast, accurate, high resolution, complete Quality Assurance of patient-specific treatment plans utilizing intensity-modulated Ion Beam Therapy, prior to their delivery to the patient. The detection medium is a tissue-equivalent water-based liquid scintillator material. A three-dimensional pattern of scintillation light, emitted upon ion beam irradiation, is reconstructed from three orthogonal two-dimensional light yield profiles, which are read out for each individual beam energy layer. The 3-D information has dose measurement accuracy 1-2% and spatial resolution 1-2 millimeters. The measurement sequence provides up to four orders of magnitude more data characterizing the treatment plan than currently commercially available alternatives, all in a time period no greater than that needed for actual delivery of the dose fraction to a patient. The system provides sophisticated control and readout of the cameras or photo-detectors, data archiving and analysis, simulation capabilities, and 3-D dose image reconstruction and visualization.
摘要翻译： Active Water Phantom旨在提供快速，准确，高分辨率，完整的质量保证，在使用强度调制离子束治疗之前，将患者特异性治疗计划交付给患者。检测介质是组织等效的水基液体闪烁体材料。从三个正交的二维光产生曲线重建离子束照射时发射的闪烁光的三维图案，其对于每个单独的光束能量层读出。 3-D信息的剂量测量精度为1-2％，空间分辨率为1-2毫米。测量序列提供比目前商业上可获得的替代物多达四个数量级的表征治疗计划的数据，所有这些数据在不大于向患者实际递送剂量分数所需的时间内。该系统提供复杂的摄像机或光电检测器的控制和读出，数据归档和分析，仿真功能和3-D剂量图像重建和可视化。

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