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1. 发明申请

WO2019096904A1 MIXING AND/OR RECONSTITUTION SYSTEM 审中-公开
公开(公告)号：WO2019096904A1
公开(公告)日：2019-05-23
申请号：PCT/EP2018/081369
申请日：2018-11-15
申请人： SANOFI
发明人： SCHABBACH, Michael , HARVEY, Charlotte Emma , HUANG, Congyi , FREARSON, Timothy Charles , NORMAN, Alexander David , POTTER, Andrew Robert , STACEY, Gary
IPC分类号： A61M5/178
CPC分类号： A61M5/1782 , A61J1/2096 , A61M5/19 , A61M5/20 , A61M5/2053 , A61M5/2066 , A61M5/2448 , A61M5/31596 , A61M5/445 , A61M2005/2013 , A61M2005/2474 , A61M2005/3128 , A61M2005/31598 , A61M2005/3267 , A61M2205/0272 , A61M2209/04 , A61M2209/045
摘要： The invention refers to a mixing and/or reconstitution system which reduces the possibility of user error and provides an easy and automatic operation comprising -a device(300, 400) containing a first material within a first chamber (305, 405), further comprising a housing (301, 401) and a plunger (307, 407), -a vial (308, 408) containing a second material within a second chamber (309, 409), wherein at least one of the first material and the second material is a fluid, -a base station (350, 450) comprising at least one drive unit (370, 470), a first slide (374) and a driver, and -a needle (302, 402), wherein the device (300, 400) and the vial (308, 408) are attachable to the base station in an initial position in which the device (300, 400) and the vial (308, 408) have a pre-defined distance to each other, wherein the needle (302, 402) is attached to the device (300, 400) and fluidly connected with the first chamber (305, 405) of the device (300, 400), wherein in the initial position the at least one drive unit (370, 470) is connected to the first slide (374) that moves the vial (308, 408) and/or the housing (301, 401) of the device (300, 400) relative to each other in an axial direction of the device (300, 400) along a pre-defined distance into an activated position, in which the needle (302, 402) is fluidly connected with the second chamber (309, 409) and wherein in the activated position the at least one drive unit (370, 470) is connected to the driver that moves the plunger (307, 407) in the axial direction of the device (300, 400) along a pre- defined distance such that during fluid connection of the needle (302, 402) with the second chamber (309, 409) the first material is expelled from the first chamber (305, 405) of the device into the second chamber (309, 409) of the vial (308, 408) or the second material is expelled from the second chamber (309, 409) of the vial (308, 408) into the first chamber (305, 405) of the device (300, 400). The invention further refers to a base station thereto, a supporting unit and a respective mixing and/or reconstitution method.

2. 发明申请

WO2019084371A1 ADAPTOR FOR VIALS AND SYRINGES 审中-公开
公开(公告)号：WO2019084371A1
公开(公告)日：2019-05-02
申请号：PCT/US2018/057664
申请日：2018-10-26
申请人： COOK REGENTEC LLC
发明人： FISCHER, Frank, J.
IPC分类号： A61J1/20
CPC分类号： A61J1/201 , A61J1/2044 , A61J1/2055 , A61J1/2096
摘要： Adaptors 100 for penetrating a wall of a container (200, 215), such as a syringe or a vial, are arranged to receive a portion of the container (200, 215) and penetrate a septum 215 of the container with a needle 140 such that an opening 300 of the needle 14 is at the same height as an adjacent inner surface 240 of the container (200, 215). Additionally, arrangements are disclosed wherein the adaptor is arranged to lock the container. The adaptors can include a window for viewing the vial's contents and/or a label of the vial, and/or indicia that corresponds to the volume of fluid in the vial.

3. 发明申请

WO2019076921A1 DISPOSITIF D'INJECTION MANUELLE 审中-公开
公开(公告)号：WO2019076921A1
公开(公告)日：2019-04-25
申请号：PCT/EP2018/078287
申请日：2018-10-16
申请人： EDIX SA
发明人： CHERIF-CHEIKH, Roland , BOURGOIS, Tabatha , PARETA BELTRAN, Lluis , LACOMBE, Frederic , LACHAMP, Laurence
IPC分类号： A61M5/315 , A61M5/24 , A45D40/04 , B65D83/00 , G01F11/02 , A61M5/46 , A61J1/20 , A61J1/06 , A61M5/32 , A61M5/34
CPC分类号： A61M5/31501 , A45D34/00 , A45D40/04 , A45D2200/055 , A61J1/062 , A61J1/065 , A61J1/2037 , A61J1/2096 , A61M5/24 , A61M5/2448 , A61M5/2466 , A61M5/31525 , A61M5/3155 , A61M5/31576 , A61M5/31583 , A61M5/31586 , A61M5/3202 , A61M5/329 , A61M5/3293 , A61M5/34 , A61M5/46 , A61M2005/2411 , A61M2005/2488 , B65D83/0011 , G01F11/025
摘要： La présente invention concerne un dispositif d'injection du type comportant un corps (3) cylindrique renfermant un réservoir (5) contenant un produit à injecter, qui est ouvert à une extrémité sur une aiguille d'injection (7) et qui est fermé à son autre extrémité par un piston (9) monté mobile en translation dans le réservoir sous la commande d'une tige de piston (11) pourvue d'un organe de commande (13), ce dispositif comportant des moyens de contrôle de la quantité de produit à délivrer. Ce dispositif est caractérisé en ce que lesdits moyen de contrôle sont disposés sur le corps (3) en une zone se situant hors d'une zone de préhension à pleine main du corps (16). La présente invention concerne également un dispositif de remplissage pour dispositif d'injection.

4. 发明申请

WO2019055197A1 DEVICES AND SYSTEMS WITH AN INTERNAL DISPLACEMENT MECHANISM FOR CONTAMINANT-FREE ENGAGEMENT OF MEDICAL VESSELS AND DEVICES 审中-公开
公开(公告)号：WO2019055197A1
公开(公告)日：2019-03-21
申请号：PCT/US2018/048060
申请日：2018-08-27
申请人： NAYGAUZ, Mikael
发明人： NAYGAUZ, Mikael
IPC分类号： A61J1/20 , A61J3/00 , A61M39/18 , A61J1/05 , B65D39/00 , A61J1/14
CPC分类号： A61J1/1443 , A61J1/10 , A61J1/1475 , A61J1/2024 , A61J1/2037 , A61J1/2048 , A61J1/2082 , A61J1/2089 , A61J1/2096
摘要： The present invention relates, in some embodiments thereof, to systems, device and methods for establishing a contaminant-free fluid passageway between vessels. In some embodiments of the invention, the systems and devices of the invention include a first connection interface configured to be coupled to a first vessel, and a second connection interface configured to be coupled to a second vessel, the first and second connection interfaces configured to engage with each other and entrap contaminants, the first connection interface and the second connection interface, following the engagement, are configured to internally displace within the first vessel or the second vessel, while allowing for a contaminant-free fluid passageway and hermetically sealed engagement of the vessels.

5. 发明申请

WO2018172868A1 REDUCER FOR A SYRINGE 审中-公开
公开(公告)号：WO2018172868A1
公开(公告)日：2018-09-27
申请号：PCT/IB2018/051284
申请日：2018-02-28
申请人： BORMIOLI PHARMA S.R.L.
发明人： PAGANUZZI, Valerio
IPC分类号： A61J1/20 , A61M39/20
CPC分类号： A61J1/2075 , A61J1/2096 , A61M2039/205
摘要： A reducer applicable to an opening of a container and identifying a seat (2) comprising a bottom (21) and a lateral flank (22) that define a concavity (20) intended for housing a portion of a syringe doser; said bottom (21) comprising an opening (210) suitable for allowing the passage of a fluid present in the container. The reducer (1) comprises a passage (3) intended for enabling the air to enter the container to compensate for the depressurisation induced in the container by the aspiration of the fluid by the syringe doser. The passage (3) is outside the concavity and allows the reducer (1) to be crossed for placing the inside and the outside of the container in fluid communication.

6. 发明申请

WO2018129047A1 ANESTHETICS NEEDLE DEVICE TO FACILITATE THE USE OF BUFFERED ANESTHETICS 审中-公开
公开(公告)号：WO2018129047A1
公开(公告)日：2018-07-12
申请号：PCT/US2018/012189
申请日：2018-01-03
申请人： FRAME, Haley, Lee , FRAME, Wesley, Michael
发明人： FRAME, Haley, Lee , FRAME, Wesley, Michael
IPC分类号： A61J1/20
CPC分类号： A61J1/2096 , A61J1/062 , A61J1/20 , A61J1/2013
摘要： An anesthetic needle device having a buffer cartridge for storing and moving a buffer solution into a syringe having an anesthetic carpule; an exhaust cartridge for transferring a buffer solution into a syringe having an anesthetic carpule and also receiving displaced anesthetic from the anesthetic carpule; and a needle assembly for injecting a buffer solution into a syringe having an anesthetic carpule and also injecting a buffered-anesthetic into a patient.

7. 发明申请

WO2018071704A1 VENTED FLUID TRANSFER LID 审中-公开
标题翻译：通风的流体转移盖子
公开(公告)号：WO2018071704A1
公开(公告)日：2018-04-19
申请号：PCT/US2017/056391
申请日：2017-10-12
申请人： NEOMED, INC.
发明人： DOORNBOS, David, A. , CARY, Mariann , DAVIS, Benjamin, M.
IPC分类号： A61J1/14 , B65D47/06 , A61J1/20
CPC分类号： B65D47/143 , A61J1/1418 , A61J1/1468 , A61J1/1481 , A61J1/1487 , A61J1/2075 , A61J1/2096 , A61J9/085 , A61M1/062 , B65D47/06 , B67D3/0041 , C23C16/4412
摘要： A vented transfer lid includes an inner collar projecting from a top panel of the transfer lid and having an outer circumferential surface having a texturized EDM surface finish. In some example forms, an interior surface of the top panel includes a texturized EDM surface finish. In example forms, the transfer lid includes a transfer port wherein at least a portion of an interior surface of the transfer port includes a texturized EDM surface finish. In other embodiments, at least a portion of the vented transfer lid comprises a nonpolar boundary such that fluids exposed to the nonpolar boundary bead and form droplets having a dimension rendering them incapable of passing through one or more vent paths.
摘要翻译：排气转移盖包括从转移盖的顶板突出并具有具有纹理化EDM表面光洁度的外圆周表面的内套环。在一些示例形式中，顶部面板的内表面包括纹理化的EDM表面光洁度。在示例形式中，传送盖包括传送端口，其中传送端口的内表面的至少一部分包括纹理化的EDM表面光洁度。在其它实施例中，通风传送盖的至少一部分包括非极性边界，使得流体暴露于非极性边界珠并且形成具有使得它们不能穿过一个或多个通风路径的尺寸的液滴。

8. 发明申请

WO2017207758A3 A SHIELDING DEVICE USEFUL FOR MANIPULATING A RADIOACTIVE SOLUTION 审中-公开
标题翻译：用于操纵放射性溶液的屏蔽设备
公开(公告)号：WO2017207758A3
公开(公告)日：2018-01-18
申请号：PCT/EP2017063452
申请日：2017-06-02
申请人： TEVA MEDICAL LTD , NORTON HEALTHCARE LTD
发明人： LE MAITRE JULIEN , LEMER PIERRE-MARIE
IPC分类号： A61J1/20 , A61M5/178 , G21F5/018
CPC分类号： A61M5/1785 , A61J1/1406 , A61J1/201 , A61J1/2048 , A61J1/2082 , A61J1/2096 , A61M5/1782 , G21F5/015 , G21F5/018
摘要： The present disclosure relates to a device (1) for sampling and/or injection of a radioactive solution (S) in a vial (2), wherein the vial (2) comprises an opening closed by a puncturable closure member (3). The device (1) comprises a container (7) adapted to receive said vial (2) and a vial adaptor (4), said vial adaptor (4) having a longitudinal axis (L1), provided at a first end (41) with a hollow spike (42) adapted to pierce said puncturable closure member (3) when the vial adaptor (4) is mounted on the vial (2), and at a second end (43) with connection means (5) adapted for its removable connection to a syringe (6), the container (7) comprising: - a container body (71) adapted to receive said vial (2), the container body (71) having an opening (711), and - a vial adaptor support structure (72) configured for being mounted onto the opening (711) of the container body (71), and comprising retention means configured for enabling releasable retention of said vial adaptor (4) within said vial adaptor support structure (72), and wherein the vial adaptor support structure (72) and the container body (71) are made at least partially of a radioprotective material for providing protection against ionizing radiation.
摘要翻译：本公开涉及用于在小瓶（2）中取样和/或注射放射性溶液（S）的装置（1），其中小瓶（2）包括由可穿透闭合构件（3）封闭的开口。所述装置（1）包括适于容纳所述小瓶（2）和小瓶适配器（4）的容器（7），所述小瓶适配器（4）具有纵向轴线（L1）当小瓶适配器（4）安装在小瓶（2）上时适于刺穿所述可穿透闭合构件（3）的中空钉（42），以及适于可拆卸地连接装置（5）的第二端部（43）所述容器（7）包括： - 适于容纳所述小瓶（2）的容器主体（71），所述容器主体（71）具有开口（711），以及 - 小瓶适配器支撑件（71）的所述开口（711）上的结构（72），并且包括保持装置，所述保持装置被配置为能够将所述瓶适配器（4）可释放地保持在所述瓶适配器支撑结构（72）内，并且其中小瓶适配器支撑结构（72）和容器主体（71）至少部分由防辐射材料制成，用于再次提供保护电离辐射。

9. 发明申请

WO2017132625A1 SYSTEM AND METHOD FOR INJECTION COMPONENT PREPARATION 审中-公开
标题翻译：用于注射成分制备的系统和方法
公开(公告)号：WO2017132625A1
公开(公告)日：2017-08-03
申请号：PCT/US2017/015511
申请日：2017-01-27
申请人： CREDENCE MEDSYSTEMS, INC.
发明人： SHLUZAS, Alan E. , DIAZ, Stephen H.
IPC分类号： A61J1/20
CPC分类号： A61J1/2093 , A61J1/2013 , A61J1/2017 , A61J1/2037 , A61J1/2055 , A61J1/2058 , A61J1/2065 , A61J1/2068 , A61J1/2075 , A61J1/2089 , A61J1/2096
摘要： An assembly for mixing drug components includes a housing to at least partially hold a first drug component container and a second drug component container. The assembly also includes a transfer member having first and second ends to fluidly couple the respective first and second drug component containers. The assembly further includes a pressure member to fluidly couple the first drug component container to a pressure generation chamber. In addition, the assembly includes an energy storage member to generate pressure in the pressure generation chamber to transfer a fluid from the first drug component container into the second drug component container. Moreover, the assembly includes an exit member to fluidly couple the second drug component container to an exterior of the assembly.
摘要翻译：用于混合药物组分的组件包括用于至少部分地保持第一药物组分容器和第二药物组分容器的壳体。该组件还包括传送构件，传送构件具有第一和第二端以流体地联接相应的第一和第二药物成分容器。该组件还包括将第一药物成分容器流体连接至压力发生室的压力构件。另外，该组件包括储能部件，用于在压力发生室中产生压力以将流体从第一药物成分容器转移到第二药物成分容器中。而且，该组件包括将第二药物成分容器流体连接到组件外部的出口构件。

10. 发明申请

WO2017108558A1 AN INJECTOR DEVICE FOR ASSISTING ASSEMBLY OF AN INJECTOR UNIT 审中-公开
标题翻译：一种注射器装置，用于辅助注射器单元的组装
公开(公告)号：WO2017108558A1
公开(公告)日：2017-06-29
申请号：PCT/EP2016/081126
申请日：2016-12-15
申请人： MEDICOM INNOVATION PARTNER A/S
发明人： FISHLEIN, Christian , OLESEN, Jan , JOHANSEN, Esben W.
IPC分类号： A61M5/142 , A61M5/145 , A61M5/178 , A61J1/20
CPC分类号： A61J1/2096 , A61J1/20 , A61J1/2058 , A61J1/2065 , A61M5/14216 , A61M5/1452 , A61M5/178 , A61M2207/00 , A61M2207/10
摘要： An injector device (12) for preparing and delivering a medical drug is disclosed. A housing (13) of the injector device (12) defines a cavity arranged to receive a disposable injector unit (1) being assembled from at least two separate injector parts (2, 3, 4, 10). A holding mechanism (17, 33) is arranged to fixate a first injector part (2, 3, 4, 10) of the disposable 5 injector unit (1). A force transferring mechanism (18, 22, 23, 24) is arranged to transfer a linear force and/or a torque from a motor (15, 20, 21) to a second injector part (2, 3, 4, 10) of the disposable injector unit (1), thereby causing the second injector part (2, 3, 4, 10) to perform translational and/or rotational movements relative to the first injector part (2, 3, 4, 10), thereby causing the first injector part (2, 3, 4, 10) and the second injector part (2, 3, 4, 10 10) to be assembled in an automatic or assisted manner.
摘要翻译：公开了一种用于制备和输送医疗药物的注射器装置（12）。注射器装置（12）的壳体（13）限定了空腔，该空腔布置成接收由至少两个单独的注射器部件（2,3,4,10）组装的一次性注射器单元（1）。保持机构（17,33）布置成固定一次性注射器单元（1）的第一注射器部件（2,3,4,10）。力传递机构（18,22,23,24）被布置成将来自马达（15,20,21）的线性力和/或扭矩传递至第二喷射器部件（2,3,4,10），该第二喷射器部件由此使得所述第二注射器部件（2,3,4,10）相对于所述第一注射器部件（2,3,4,10）进行平移运动和/或旋转运动，从而导致所述第二注射器部件第一注射器部件（2,3,4,10）和第二注射器部件（2,3,4,1010）以自动或辅助方式组装。

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