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1. 发明申请

WO1992012673A1 ADJUSTABLE SUTURES AND METHODS OF MAKING AND USING SAME 审中-公开
标题翻译：可调节的方法和使用它的方法
公开(公告)号：WO1992012673A1
公开(公告)日：1992-08-06
申请号：PCT/US1992000440
申请日：1992-01-17
申请人： EATON, Alexander, M. , PURUT, Lemil, M. , L'ESPERANCE, Francis, A., Jr.
IPC分类号： A61B17/00
CPC分类号： A61L17/04 , A61B17/06166 , A61F2002/30103 , A61F2210/0047 , A61F2250/0067
摘要： A surgical suture is made from materials which, upon the application of at least one source of non-frictional energy, such as may be imparted by using a laser, alter dimension. In essence, these sutures can be made to contract and/or expand after implantation in tissues and/or prosthetic materials. The absorbtion of energy may be enhanced by the addition to the suture material of an energy absorbing substance, and especially a substance that is selected to absorb radiation at the wavelength of a laser used to effect the dimensional change. Preferred sutures are comprised of cross-linked polyolefins. These fibers may also be formed into composite structures, such as a braided structure, to provide a composite suture having selectively alterable component suture elements.
摘要翻译：手术缝合线由材料制成，在施加至少一种非摩擦能量源时，例如可以通过使用激光来赋予外科缝合线来改变尺寸。实质上，这些缝线可以在植入组织和/或假体材料之后收缩和/或扩张。能量的吸收可以通过加入能量吸收物质的缝合材料，特别是被选择吸收用于实现尺寸变化的激光波长的辐射的物质而增强。优选的缝线由交联聚烯烃组成。这些纤维也可以形成复合结构，例如编织结构，以提供复合缝合线，其具有可选择的可变组件缝合元件。

2. 发明申请

WO01049353A2 VARIABLE SHAPE GUIDE APPARATUS 审中-公开
标题翻译：可变形形状指南
公开(公告)号：WO01049353A2
公开(公告)日：2001-07-12
申请号：PCT/CA2001/000006
申请日：2001-01-05
IPC分类号： A61B1/005 , A61F2/00 , A61F2/06 , A61F2/88 , A61M25/01
CPC分类号： A61M25/0158 , A61B1/0058 , A61F2/88 , A61F2210/0047
摘要： The apparatus includes a flexible, elongated tubular member and is comprised of a tube of superelastic metal which in response to changing temperatures resists to a greater or lesser degree the bending moment imposed by a biasing element, thereby altering the shape of the tubular member as a function of temperature and producing a broad range of shapes.
摘要翻译：该装置包括柔性细长的管状构件，并且包括超弹性金属管，其响应于变化的温度或多或少地抵抗由偏压元件施加的弯矩，从而将管状构件的形状改变为温度的功能，并产生广泛的形状。

3. 发明申请

WO1993021920A1 SYNERGISTIC COMBINATION OF A SUBSTANCE WITH GASTRIC ACID SECRETION INHIBITING EFFECT AND AN ACID DEGRADABLE ANTIBIOTIC 审中-公开
标题翻译：物质与胃酸分泌抑制作用和酸可降解抗生素的协同联合
公开(公告)号：WO1993021920A1
公开(公告)日：1993-11-11
申请号：PCT/SE1993000327
申请日：1993-04-20
申请人： AKTIEBOLAGET ASTRA
发明人： AKTIEBOLAGET ASTRA , EEK, Arne, Torsten , SJÖSTRAND, Sven, Erik
IPC分类号： A61K31/44
CPC分类号： A61K31/70 , A61B17/0469 , A61B17/06066 , A61B17/34 , A61F2002/30095 , A61F2002/30103 , A61F2210/0023 , A61F2210/0047 , A61K31/00 , A61K31/43 , A61K31/44 , A61K45/06 , A61K2300/00 , A61K31/40
摘要： The invention consists of a combination of a substance that increases the intragastric pH and an acid degradable antibacterial compound. By this combined product regimen it will be possible to obtain maximal local antibacterial effect of acid degradable antibiotics as well as enhanced bioavailability of the active antibiotic, thus resulting in higher amounts of the active compound in the gastric mucosa due to secretion of weak bases. Both pharmacological effects contribute to drastically increased antimicrobial capacity of acid degradable antibiotics to be used against local infections in the gastrointestinal tract causing gastritis and/or peptic ulcer. The invention also selects to the use of said combination and a process for the preparation thereof.
摘要翻译：本发明由增加胃内pH的物质与酸降解抗菌化合物的组合组成。通过该组合产品方案，可以获得酸降解抗生素的最大局部抗菌作用以及提高活性抗生素的生物利用度，从而由于弱碱分泌导致胃粘膜中活性化合物的量增加。两种药理作用都有助于大幅提高酸降解抗生素的抗菌能力，以抵抗胃肠道局部感染引起胃炎和/或消化性溃疡。本发明还选择了所述组合的用途及其制备方法。

4. 发明申请

WO2005027792A1 IMPLANT WITH SHAPE MEMORY 审中-公开
标题翻译：植入形状记忆
公开(公告)号：WO2005027792A1
公开(公告)日：2005-03-31
申请号：PCT/EP2004/010692
申请日：2004-09-23
申请人： ANGIOMED GMBH & CO. MEDIZINTECHNIK KG , BLANK, Thiemo , PATHAK, Chandrashekhar, Prabhakar
发明人： BLANK, Thiemo , PATHAK, Chandrashekhar, Prabhakar
IPC分类号： A61F2/06
CPC分类号： B29C61/00 , A61F2/82 , A61F2210/0038 , A61F2210/0042 , A61F2210/0047 , B29C61/02 , B29L2031/7534
摘要： An implant having capability to expand and contract radially through a range of diameters, with corresponding changes in the cross-sectional area of the lumen, said implant exhibiting a remembered configuration in which the diameter of the implant is at the low end of said range of diameters, such that the implant is prompted to change its configuration towards said remembered configuration, that is, towards a reduced diameter configuration, upon the imposition on the implant of outside stimulus; said implant being characterised by: a molecule distributed within its bulk volume that preferentially responds to an applied field that permeates said volume, wherein said applied field constitutes the outside stimulus, and the preferential response of the molecule provides the prompt on the implant to change to the said remembered configuration.
摘要翻译：植入物具有通过一定范围的直径而径向膨胀和收缩的能力，以及内腔的横截面面积的相应变化，所述植入物呈现出记忆结构，其中植入物的直径处于所述范围的低端直径，使得植入物被迫改变其构型朝着所述记忆构型改变，即，在施加在外部刺激的植入物上时朝向减小的直径构型; 所述植入物的特征在于：分布在其本体体积内的分子优先响应渗透所述体积的施加的场，其中所述施加的场构成外部刺激，并且分子的优先响应提供植入物上的提示，以改变为所记住的配置。

5. 发明申请

WO00010485A1 SHAPE MEMORY TUBULAR STENT 审中-公开
标题翻译：形状记忆管状茎
公开(公告)号：WO00010485A1
公开(公告)日：2000-03-02
申请号：PCT/CA1999/000767
申请日：1999-08-20
IPC分类号： A61F2/00 , A61F2/06 , A61F2/90
CPC分类号： A61F2/954 , A61F2/856 , A61F2/90 , A61F2002/065 , A61F2002/9505 , A61F2210/0047
摘要： A stent radially expandable from a radially contracted introduction state into a radially expanded position state, in which the final shape of the stent can be controlled by varying the amount and places photo-thermal energy is projected onto the interior surfaces of the tubes from which the stent is fabricated.
摘要翻译：可从径向收缩的引入状态径向膨胀到径向扩张位置状态的支架，其中可以通过改变量来控制支架的最终形状，并且将光热能量投射到管的内表面上，制造支架。

6. 发明申请

WO2009015234A3 POST-IMPLANT LENS POWER MODIFICATION 审中-公开
标题翻译：后植入镜头电源修改
公开(公告)号：WO2009015234A3
公开(公告)日：2009-04-30
申请号：PCT/US2008070931
申请日：2008-07-23
申请人： POWERVISION INC , SMILEY TERAH WHITING , SHADDUCK JOHN H , ESCH VICTOR C , SCHOLL JOHN A , ARGENTO CLAUDIO , CHESKIN BARRY , SMITH DAVID JOHN , BURNS DENISE H
发明人： SMILEY TERAH WHITING , SHADDUCK JOHN H , ESCH VICTOR C , SCHOLL JOHN A , ARGENTO CLAUDIO , CHESKIN BARRY , SMITH DAVID JOHN , BURNS DENISE H
IPC分类号： A61F2/16
CPC分类号： A61F2/1613 , A61F2/1624 , A61F2/1627 , A61F2/1635 , A61F2/1648 , A61F2210/0047 , A61F2250/0003 , A61F2250/0004 , A61F2250/0053
摘要： An accommodating intraocular lens (50) adapted for a post-implant modification is described. The lens includes an optic portion (56, 58, 62), a non-optic portion (52, 54) disposed peripherally from the optic portion and adapted to engage a lens capsule, wherein the intraocular lens is adapted to change power in response to ciliary muscle movement. The lens also includes an actuatable element (60) adapted to be actuated by an external energy source to change an optical parameter of the intraocular lens.
摘要翻译：描述适于植入后修改的适应性眼内透镜（50）。透镜包括光学部分（56,58,62），从光学部分周向设置并适于接合透镜胶囊的非光学部分（52,54），其中眼内透镜适于响应于睫状肌运动。透镜还包括适于由外部能量源致动以改变眼内透镜的光学参数的致动元件（60）。

7. 发明申请

WO2009015234A2 POST-IMPLANT LENS POWER MODIFICATION 审中-公开
标题翻译：后植入镜头电源修改
公开(公告)号：WO2009015234A2
公开(公告)日：2009-01-29
申请号：PCT/US2008/070931
申请日：2008-07-23
申请人： POWERVISION, INC. , SMILEY, Terah, Whiting , SHADDUCK, John, H. , ESCH, Victor, C. , SCHOLL, John, A. , ARGENTO, Claudio , CHESKIN, Barry , SMITH, David, John , BURNS, Denise, H.
发明人： SMILEY, Terah, Whiting , SHADDUCK, John, H. , ESCH, Victor, C. , SCHOLL, John, A. , ARGENTO, Claudio , CHESKIN, Barry , SMITH, David, John , BURNS, Denise, H.
IPC分类号： A61F2/16
CPC分类号： A61F2/1613 , A61F2/1624 , A61F2/1627 , A61F2/1635 , A61F2/1648 , A61F2210/0047 , A61F2250/0003 , A61F2250/0004 , A61F2250/0053
摘要： Post-implant modifications to an intraocular lens. In some embodiments the lens is an accommodating intraocular lens.
摘要翻译：植入后修改眼内透镜。在一些实施例中，透镜是容纳的眼内透镜。

8. 发明申请

WO0149353A3 VARIABLE SHAPE GUIDE APPARATUS 审中-公开
标题翻译：可变形形状指南
公开(公告)号：WO0149353A3
公开(公告)日：2002-04-18
申请号：PCT/CA0100006
申请日：2001-01-05
申请人： WARAM THOMAS , UNSWORTH JOHN
发明人： WARAM THOMAS , UNSWORTH JOHN
IPC分类号： A61B1/005 , A61F2/00 , A61F2/06 , A61F2/88 , A61M25/01
CPC分类号： A61M25/0158 , A61B1/0058 , A61F2/88 , A61F2210/0047
摘要： The apparatus includes a flexible, elongated tubular member and is comprised of a tube of superelastic metal which in response to changing temperatures resists to a greater or lesser degree the bending moment imposed by a biasing element, thereby altering the shape of the tubular member as a function of temperature and producing a broad range of shapes.
摘要翻译：该装置包括柔性细长的管状构件，并且包括超弹性金属管，其响应于变化的温度或多或少地抵抗由偏压元件施加的弯矩，从而将管状构件的形状改变为温度的功能，并产生广泛的形状。

9. 发明申请

WO9822042A3 SHAPE MEMORY TUBULAR DEPLOYMENT SYSTEM 审中-公开
标题翻译：形状记忆管状部署系统
公开(公告)号：WO9822042A3
公开(公告)日：1998-08-27
申请号：PCT/CA9700842
申请日：1997-11-13
申请人： UNSWORTH JOHN
发明人： UNSWORTH JOHN , WARAM THOMAS
IPC分类号： A61F2/84 , A61F2/00 , A61F2/06 , A61F2/88
CPC分类号： A61F2/88 , A61F2/95 , A61F2210/0047 , A61M25/0043 , A61M25/0158 , A61M2025/0064
摘要： Tubes made from shape memory alloy (SMA) assume their original shape when heated to their austenite finish temperature by directing photo-thermal or electrical energy inside parts of the tube using an optical fiber or conductors, the remainder of the tube acting as a heat sink. Using this method of photo-thermal heating or joule heating, virtually any predetermined shape can be made from tubes, or objects having tubular paasages, in a controlled manner with very little heat being transferred to the material surrounding the outside of the tube. The optical fiber may also be used to detect the transformation of the material at the heated site from martensite to austenite and the temperature of the heated site, and use this information to control deployment of the device and reduce overheating of the tube and the material surrounding the outside of the tube.

10. 发明申请

WO0234171A8 LATERALLY EXPANDING INTERVERTEBRAL FUSION DEVICE 审中-公开
标题翻译：横向膨胀融合器件
公开(公告)号：WO0234171A8
公开(公告)日：2002-08-22
申请号：PCT/US0146076
申请日：2001-10-23
申请人： SDGI HOLDINGS INC , ESTES BRADLEY T , DICKSON ANDREW M
发明人： ESTES BRADLEY T , DICKSON ANDREW M
IPC分类号： A61L27/00 , A61F2/00 , A61F2/02 , A61F2/28 , A61F2/30 , A61F2/44 , A61F2/46
CPC分类号： A61F2/4455 , A61F2/4465 , A61F2002/2817 , A61F2002/2835 , A61F2002/30014 , A61F2002/30032 , A61F2002/30062 , A61F2002/30095 , A61F2002/30102 , A61F2002/30103 , A61F2002/30131 , A61F2002/30133 , A61F2002/30176 , A61F2002/30177 , A61F2002/30235 , A61F2002/30579 , A61F2002/30971 , A61F2002/4475 , A61F2002/448 , A61F2002/4635 , A61F2210/0004 , A61F2210/0023 , A61F2210/0042 , A61F2210/0047 , A61F2230/0013 , A61F2230/0015 , A61F2230/0054 , A61F2230/0056 , A61F2230/0069 , A61F2250/0018 , A61F2250/003
摘要： The invention relates to intervertebral spacers (10, 40, 82A/B, 100, 120, 150, 180, 190 and 220) for use in orthopedic treatment of spinal defects. The intervertebral space is formed of a shape memory polymer. The spacer can be fabricated into a desired configuration and then deformed into an alternative or deformed configuration. Cooling the deformed spacer effectively freezes the spacer into its deformed conformation. The deformed configuration can be selected to facilitate implantation of the spacer into a prepared disc space between adjacent vertebrae. During operation, the surgeon can heat the spacer to allow it to revert to its original configuration. The spacer in its original conformation is sized to restore and/or maintain the adjacent vertebrae in a desired conformation and disc space height.
摘要翻译：本发明涉及用于骨科治疗脊柱缺损的椎间隔垫（10,40,82A / B，100,120,150,180,190和220）。椎间隙由形状记忆聚合物形成。间隔件可以制造成所需的构造，然后变形为替代或变形构型。冷却变形的间隔物有效地将间隔件冻结成其变形构型。可以选择变形的构造以便于将间隔件植入到相邻椎骨之间的制备的椎间盘空间中。在手术过程中，外科医生可以加热间隔器以使其恢复到其原始配置。其原始构造中的间隔物的尺寸被设计成恢复和/或维持相邻椎骨具有期望的构象和椎间盘空间高度。

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