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    • 1. 发明申请
    • SELF-FORMING ORTHOPEDIC IMPLANTS
    • 自我形成的骨科植入物
    • WO0234310A3
    • 2002-10-17
    • PCT/US0145406
    • 2001-10-23
    • SDGI HOLDINGS INCDICKSON ANDREW MESTES BRADLEY T
    • DICKSON ANDREW MESTES BRADLEY T
    • A61L27/00A61F2/44A61L31/04A61L31/14A61L27/14A61L27/50
    • A61L31/14A61L31/04A61L2400/16A61L2430/02
    • This invention relates to a self-forming orthopedic implant (10, 40, 60A/B, 100, 140, 200, 250, 280 and 330). The implant is formed a shape memory polymer. The implant can be provided in an original configuration selected to facilitate orthopedic treatment of bone defects, fixation of bone fragments and fractures, or selected to induce bone structures to conform to a desired anatomical configuration. Non-limiting examples of preferred configurations include bone spacers or bone plates, connective tissue replacements (i.e., tendons, ligaments, and/or cartilage). In preferred forms, the implant is deformed to an alternative configuration prior to implantation. Upon application of selected stimuli, for example, heating the implant to a temperature where the shape memory polymeric material becomes elastic induces the implant to revert to its original configuration. In use, when the implant is subjected to the selected stimuli, it conforms to a selected bone tissue or alternatively conforms to a configuration that urgers bone structures into a desired alignment and/or configuration. When used to replace connective tissues, the implant exhibits a tensile strengh to allow the adjacent bone structure to articulate, yet provides sufficient force to urge the bone structures into a desired position and alignment.
    • 本发明涉及一种自成形整形外科植入物(10,40,60A / B,100,140,​​200,250,280和330)。 植入物形成形状记忆聚合物。 植入物可以被提供为原始构型,其被选择为促进骨缺损的整形外科治疗,骨碎片和骨折的固定,或者被选择以诱导骨结构以符合期望的解剖结构。 优选构造的非限制性实例包括骨间隔器或骨板,结缔组织替代物(即肌腱,韧带和/或软骨)。 在优选的形式中,植入物在植入之前变形为替代构型。 例如,在施加选择的刺激时,将植入物加热到形状记忆聚合物材料变得弹性的温度,导致植入物恢复到其原始构造。 在使用中,当植入物受到选择的刺激时,其与所选择的骨组织一致或者可选地符合将骨结构促成为期望的对准和/或构造的构造。 当用于替代结缔组织时,植入物表现出拉伸强度,以允许相邻骨结构关节连接,但提供足够的力将骨结构推动到期望的位置和对齐。
    • 2. 发明申请
    • VERTEBRAL IMPLANT FOR PROMOTING ARTHRODESIS OF THE SPINE
    • 用于促进脊椎动物的VERTEBRAL植入物
    • WO0168005A3
    • 2002-08-29
    • PCT/US0108073
    • 2001-03-14
    • SDGI HOLDINGS INCLIU MINGYANFRUH HANS-JOACHIMEBNER HARALDESTES BRADLEY T
    • LIU MINGYANFRUH HANS-JOACHIMEBNER HARALDESTES BRADLEY T
    • A61B17/58A61F2/00A61F2/28A61F2/30A61F2/44A61F2/46
    • A61F2/447A61F2/30965A61F2/442A61F2/4611A61F2002/2835A61F2002/3008A61F2002/30271A61F2002/30774A61F2002/30785A61F2002/30789A61F2002/4475A61F2230/0082A61F2250/0098
    • This invention provides a vertebral spacer (1, 80) for impaction in a disc space to restore and/or maintain desired disc space height and spinal orientation. The spacer has an elongated basis body (2, 82) having a generally lens-shape provided by convex upper and lower surfaces (24, 26, 86, and 87). Bearing surfaces (8, 8',9, 9', 98 and 100) are provided on the cross-edge surfaces of the endwalls (6, 7, 94 and 96). Grooves (16, 16' and 104) are provided in the upper and lower surfaces positioned between the bearing surfaces. The spacer (1, 80) can be prepared from a wide variety of materials including metallic materials, synthetic materials, polymeric materials, ceramic materials, and composite materials including reinforced materials i.e. glass, fiber, and/or carbon fiber reinforced materials (CFRP). These preferred materials for fabricating spacers in the present invention reduce costs, increase service life and provide excellent physiological compatibility. The non-metallic material can be selected to be either a substantially permanent material, a biodegradable material or a bioerodable material. Further, the spacer material can be provided to be radio opaque to facilitate monitoring of bone in growth both into the spacer and between the opposing endplates of the adjacent vertebrae.
    • 本发明提供一种用于在椎间盘空间中撞击以恢复和/或维持期望的椎间盘高度和脊柱取向的椎间隔物(1,80)。 间隔件具有由凸形的上表面和下表面(24,26,86和87)提供的具有大致透镜形状的细长基体(2,82)。 轴承表面(8,8',9,9',98和100)设置在端壁(6,7,94和96)的交叉边缘表面上。 沟槽(16,16'和104)设置在位于支承表面之间的上表面和下表面中。 间隔物(1,80)可以由各种材料制备,包括金属材料,合成材料,聚合材料,陶瓷材料和复合材料,包括增强材料,例如玻璃,纤维和/或碳纤维增强材料(CFRP) 。 在本发明中用于制造间隔物的这些优选材料降低成本,延长使用寿命并提供优异的生理相容性。 非金属材料可以选择为基本上永久性的材料,可生物降解的材料或生物可蚀塑料。 此外,间隔物材料可以设置为无线电不透明的,以便于监测生长中的骨骼,进入间隔物和相邻椎骨的相对端板之间。