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1. 发明申请

WO2019130083A1 CONTROLLING A SURGICAL INSTRUMENT ACCORDING TO SENSED CLOSURE PARAMETERS 审中-公开
公开(公告)号：WO2019130083A1
公开(公告)日：2019-07-04
申请号：PCT/IB2018/057322
申请日：2018-09-21
申请人： ETHICON LLC
发明人： SHELTON, IV, Frederick E. , HARRIS, Jason L. , ECKERT, Chad E. , WONG, Jordan B. , YATES, David C.
IPC分类号： A61B17/00
CPC分类号： A61B17/07207 , A61B18/1445 , A61B90/37 , A61B90/98 , A61B2017/00017 , A61B2017/00022 , A61B2017/00026 , A61B2017/00061 , A61B2017/00084 , A61B2017/00119 , A61B2017/00199 , A61B2017/00221 , A61B2017/00398 , A61B2017/00734 , A61B2017/00938 , A61B2017/07214 , A61B2017/07257 , A61B2017/07271 , A61B2017/07285 , A61B2017/2927 , A61B2018/00607 , A61B2018/00994 , A61B2090/065 , A61B2090/0807 , A61B2090/0811 , A61B2218/008 , G16H20/40 , G16H30/40 , G16H40/67
摘要： A surgical instrument includes an end effector, a motor for opening and closing the jaws, a sensor configured to detect a tissue compression parameter associated with a tissue between the jaws, and a control circuit. The control circuit is configured to determine a value of the tissue compression parameter via the sensor as the jaws transition from the open configuration to the closed configuration, cause the motor to increase a time to transition the jaws to the closed configuration according to whether the value of the tissue compression parameter is above a first threshold, and provide feedback according to whether the value of the tissue compression parameter is below a second threshold.

2. 发明申请

WO2017055144A1 SYSTEM FOR IMPLANTING IN BONE TISSUE 审中-公开
标题翻译：用于植入骨组织的系统
公开(公告)号：WO2017055144A1
公开(公告)日：2017-04-06
申请号：PCT/EP2016/072336
申请日：2016-09-21
申请人： KONINKLIJKE PHILIPS N.V.
发明人： BABIC, Drazenko , KANAGASABAPATHI, Thirukumaran Thangaraj , VALSTER, Susanne Maaike , HENDRIKS, Bernardus Hendrikus Wilhelmus
IPC分类号： A61B17/68 , A61B17/70 , A61B17/86
CPC分类号： A61B17/68 , A61B17/7032 , A61B17/7098 , A61B17/864 , A61B17/8805 , A61B17/8875 , A61B2017/00026 , A61B2017/00057 , A61B2017/00061 , A61B2017/00128 , A61B2017/883
摘要： The invention relates a system for implanting an implantable device in bone tissue, a processing unit for such system, a method of implanting an implantable device and a method of providing information for an implanting of an implantable device. In view of the finding that a fat content in cancellous bone is higher than a fat content in compact bone, the lipids fraction, which can be determined by optical means, e.g. spectroscopy, can be used to determine correct screw placement in healthy bone.
摘要翻译：本发明涉及用于在骨组织中植入可植入装置的系统，用于这种系统的处理单元，植入可植入装置的方法和提供用于植入可植入装置的信息的方法。鉴于松质骨中的脂肪含量高于紧密骨中的脂肪含量，可以通过光学方法确定的脂质部分，例如，光谱学，可用于确定健康骨骼中正确的螺钉位置。

3. 发明申请

WO2017037056A1 ABLATIONSKATHETER MIT SENSORIK ZUR ERFASSUNG DES ABLATIONSERFOLGES 审中-公开
标题翻译：随着对确定ABLATIONSERFOLGES传感器消融导管
公开(公告)号：WO2017037056A1
公开(公告)日：2017-03-09
申请号：PCT/EP2016/070406
申请日：2016-08-30
申请人： VIMECON GMBH
发明人： MARKUS, Kai Ulf
IPC分类号： A61B18/20 , A61B18/24
CPC分类号： A61B18/24 , A61B2017/00061 , A61B2017/00084 , A61B2018/00577 , A61B2018/00791 , A61B2018/00845 , A61B2018/00869
摘要： Ablationskatheter (12) zur Ablation biologischen Gewebes, mit mindestens einer optischen Faser (14) zum Transport von Laserlicht entlang des Ablationskatheters (12) und mindestens einem Auskoppelbereich (18) zum Auskoppeln des von der optischen Faser (14) transportierten Laserlichts aus dem Katheter, wobei eine Sensorik dazu ausgebildet ist, Parameter, aus denen der Ablationserfolg ermittelt werden kann, kontinuierlich zu erfassen.
摘要翻译：消融导管（12），用于与至少一个光学纤维（14），用于沿所述消融导管激光的运输（12）和至少一个耦合输出区域（18），用于从光纤中提取所述生物组织的消融（14）输送从导管激光，其中一个传感器适于从该消融成功可以连续地确定检测参数。

4. 发明申请

WO2016028749A1 RAMAN-TRIGGERED ABLATION/RESECTION SYSTEMS AND METHODS 审中-公开
标题翻译：拉曼触发/放电系统和方法
公开(公告)号：WO2016028749A1
公开(公告)日：2016-02-25
申请号：PCT/US2015/045646
申请日：2015-08-18
申请人： MEMORIAL SLOAN KETTERING CANCER CENTER
发明人： KIRCHER, Moritz , TOLEDO-CROW, Ricardo
IPC分类号： A61B18/20
CPC分类号： A61B18/20 , A61B2017/00061 , A61B2018/00577 , A61B2018/00702 , A61B2018/00982 , A61B2018/20351 , A61B2090/373
摘要： A Raman-based resection system and methods of operation thereof are disclosed. The method includes producing, via an ablation laser, an interrogation electromagnetic radiation over a scanning point of a sample having been treated with a Raman reporter, the ablation laser illuminating the scanning point at an interrogation power level; acquiring, via a detector, a signal indicative of scattered photons emanating from the scanning point following the illumination; determining, via a processor, whether the acquired signal is indicative of the presence of the Raman reporter in and/or upon the scanning point; and, responsive to a determination of the presence of the Raman reporter in and/or upon the scanning point, producing, via the ablation laser, an ablation electromagnetic radiation over the scanning point to ablate tissue at the scanning point, wherein the ablation electromagnetic radiation is at a power level sufficient to ablate tissue.
摘要翻译：公开了一种基于拉曼的切除系统及其操作方法。所述方法包括通过消融激光产生在已经用拉曼报告物处理的样品的扫描点上的询问电磁辐射，所述消融激光以询问功率水平照射所述扫描点; 通过检测器获取指示在照明之后的扫描点发出的散射光子的信号; 通过处理器确定所获取的信号是否指示在扫描点中和/或在扫描点上的拉曼报告人的存在; 并且响应于确定所述扫描点中和/或在所述扫描点上的所述拉曼报告物的存在，通过所述消融激光产生在所述扫描点上的消融电磁辐射以在所述扫描点处烧蚀组织，其中所述消融电磁辐射处于足以消融组织的功率水平。

5. 发明申请

WO2015171754A1 DEBRIDEMENT APPARATUS USING LINEAR LORENTZ-FORCE MOTORS 审中-公开
标题翻译：使用线性LORENTZ-FORCE MOTORS的解除装置
公开(公告)号：WO2015171754A1
公开(公告)日：2015-11-12
申请号：PCT/US2015/029456
申请日：2015-05-06
申请人： MASSACHUSETTS INSTITUTE OF TECHNOLOGY
发明人： HUNTER, Ian, W. , HOGAN, Nora, Catherine , BROWN, Ashley, A.
IPC分类号： A61B17/3203 , A61M1/00 , A61B17/3209
CPC分类号： A61B17/3203 , A61B17/22 , A61B17/32037 , A61B17/32093 , A61B2017/00026 , A61B2017/00039 , A61B2017/00061 , A61B2017/00084 , A61B2017/00106 , A61B2017/00761 , A61B2017/22079 , A61B2017/22082 , A61M1/0084 , A61M1/0088 , A61M2205/05
摘要： A debridement device (100) having a controllable Lorentz-force actuator (101) is disclosed. The debridement device includes a nozzle (110) delivering a jet of debridement substance to a tissue and the jet is driven by the Lorentz-force actuator (101). The device may have a suction port f(120) or removing the debridement substance. A second Lorentz-force actuator (101) can be used for each of the jet and suction. The first and second Lorentz-force actuators for the jet and suction can also be configured to provide for continuous jet injection and continuous suction. The device may include a second nozzle (805) delivering a second jet of debridement substance to the region of tissue and the first and second jets may intersect and dissipate into a mist upon intersection to dissipate the kinetic energy of the jets. The Lorentz-force actuator may drive a reciprocating piston pump providing continuous pressure to the nozzles.
摘要翻译：公开了具有可控的洛伦兹力致动器（101）的清创装置（100）。清创装置包括将清创物质的射流输送到组织的喷嘴（110），并且射流由洛伦兹力致动器（101）驱动。该装置可具有吸入口f（120）或去除清创物质。第二个洛仑兹力致动器（101）可用于每个喷射和抽吸。用于喷射和抽吸的第一和第二洛伦兹力致动器还可以被配置成提供连续喷射和连续吸入。装置可以包括将第二清创物质喷射到组织区域的第二喷嘴（805），并且第一和第二射流可在相交处相交并消散成雾状物以消散射流的动能。洛伦兹力致动器可以驱动向喷嘴提供连续压力的往复活塞泵。

6. 发明申请

WO2015085162A1 CANCER IMMUNOTHERAPY BY RADIOFREQUENCY ELECTRICAL MEMBRANE BREAKDOWN (RF-EMB) 审中-公开
标题翻译：癌症放射免疫断层扫描（RF-EMB）
公开(公告)号：WO2015085162A1
公开(公告)日：2015-06-11
申请号：PCT/US2014/068774
申请日：2014-12-05
申请人： RFEMB HOLDINGS, LLC
发明人： ONIK, Gary, M. , MIESSAU, James, A.
IPC分类号： A61N1/05 , A61N1/04 , A61B18/14
CPC分类号： A61B18/14 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/4839 , A61B5/4848 , A61B18/1477 , A61B2017/00061 , A61B2017/00159 , A61B2018/00577 , A61B2018/00732 , A61B2018/00821 , A61B2018/00875 , A61B2018/126 , A61M5/00 , A61M2202/097 , A61M2205/054 , A61N1/325 , A61N1/327
摘要： A method of non-thermally ablating undesirable tissue in the body by application of pulsed, bipolar, instant charge reversal electrical fields of sufficient energy to cause complete and immediate cell membrane rupture and destruction. Energy is delivered through radio frequency pulses of particular frequencies, wave characteristics, pulse widths and pulse numbers, such that enhanced physical stresses are placed on the cell membrane to cause its immediate and complete destruction thereby spilling the entire cell content and membrane constituents into, the extracellular space without denaturing proteins so as to enable an immunological response to destroy and remove the target tissue and similarly marked tissue elsewhere in the subject.
摘要翻译：通过施加具有足够能量的脉冲，双极，即时电荷反转电场以引起完全和立即的细胞膜破裂和破坏的身体中不热消融不希望的组织的方法。通过特定频率，波特性，脉冲宽度和脉冲数的射频脉冲输送能量，使得增强的物理应力放置在细胞膜上，导致其立即完全破坏，从而将整个细胞内容物和膜组分浸入，没有变性蛋白质的细胞外空间，以便能够免疫应答来破坏和去除受试者其他地方的靶组织和类似标记的组织。

7. 发明申请

WO2013154708A1 SURGICAL LASER SYSTEMS AND LASER LITHOTRIPSY TECHNIQUES 审中-公开
标题翻译：手术激光系统和激光切片技术
公开(公告)号：WO2013154708A1
公开(公告)日：2013-10-17
申请号：PCT/US2013/030136
申请日：2013-03-11
申请人： AMS RESEARCH CORPORATION
发明人： CHIA, Wen-jui, Ray , XUAN, Rongwei, Jason , HASENBERG, Thomas, C. , ZHANG, Jian, James , PENG, Steven, Yihlih , RAJABHANDHARAKS, Danop
IPC分类号： A61B18/26
CPC分类号： A61B18/26 , A61B1/00009 , A61B1/307 , A61B5/0051 , A61B5/0075 , A61B5/0084 , A61B5/20 , A61B2017/00061 , A61B2017/00172 , A61B2018/00511 , A61B2018/00517 , A61B2018/00642 , A61B2018/00732 , A61B2018/0088 , A61B2018/00982 , A61B2018/207 , A61B2505/05 , A61B2562/223
摘要： A surgical laser system (100) includes a first laser source (140A), a second laser source (140B), a beam combiner (142) and a laser probe (108). The first laser source is configured to output a first laser pulse train (144, 104A) comprising first laser pulses (146). The second laser source is configured to output a second laser pulse train (148, 104B) comprising second laser pulses (150). The beam combiner is configured to combine the first and second laser pulse trains and output a combined laser pulse train (152, 104) comprising the first and second laser pulses. The laser probe is optically coupled to an output of the beam combiner and is configured to discharge the combined laser pulse train.
摘要翻译：手术激光系统（100）包括第一激光源（140A），第二激光源（140B），光束组合器（142）和激光探针（108）。第一激光源被配置为输出包括第一激光脉冲（146）的第一激光脉冲串（144,104A）。第二激光源被配置为输出包括第二激光脉冲（150）的第二激光脉冲串（148,104B）。光束组合器被配置为组合第一和第二激光脉冲串并输出包括第一和第二激光脉冲的组合激光脉冲串（152,104）。激光探针光耦合到光束组合器的输出端，并被配置为对组合的激光脉冲串进行放电。

8. 发明申请

WO2011104664A1 INTERVENTIONAL ABLATION DEVICE WITH TISSUE DISCRIMINATING CAPABILITY 审中-公开
标题翻译：具有组织分辨能力的传统解决方案
公开(公告)号：WO2011104664A1
公开(公告)日：2011-09-01
申请号：PCT/IB2011/050727
申请日：2011-02-22
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , HENDRIKS, Bernardus, Hendrikus, Wilhelmus , LUCASSEN, Gerhardus, Wilhelmus , NACHABÉ, Rami , BIERHOFF, Waltherus, Cornelis, Jozef , DESJARDINS, Adrien, Emmanuel
发明人： HENDRIKS, Bernardus, Hendrikus, Wilhelmus , LUCASSEN, Gerhardus, Wilhelmus , NACHABÉ, Rami , BIERHOFF, Waltherus, Cornelis, Jozef , DESJARDINS, Adrien, Emmanuel
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B5/0066 , A61B5/0075 , A61B5/0084 , A61B8/0841 , A61B18/02 , A61B2017/00057 , A61B2017/00061 , A61B2017/00084 , A61B2017/00106 , A61B2018/00577 , A61B2034/2063 , A61B2090/378 , G06F19/00
摘要： An interventional ablation device (1) is proposed to comprise an ablation needle (3) with an elongated body(5) and a handle(7). Adjacent to an ablation element (9) provided on the body (5), at least one or preferably two or more sensors(11-21) are provided, preferably at both of opposing sides of the ablation element (9). The ablation device (1) is adapted for detecting physiological information of tissue (27, 29, 31) surrounding an ablation site (33) based on measurement values provided by the sensors. E.g., optical sensors may be used to measure a reflectance spectrum indicating whether the adjacent tissue is healthy tissue (31), tumorous tissue (27) or ablated tissue (29). Using such information, an ablation process may be controlled.
摘要翻译：提出介入消融装置（1）包括具有细长主体（5）和手柄（7）的消融针（3）。设置在主体（5）上的消融元件（9）附近，优选地在消融元件（9）的相对两侧提供至少一个或优选两个或更多个传感器（11-21）。消融装置（1）适于基于由传感器提供的测量值来检测围绕消融部位（33）的组织（27,29,31）的生理信息。例如，光学传感器可用于测量反映光谱，其指示相邻组织是健康组织（31），肿瘤组织（27）还是消融组织（29）。使用这种信息，可以控制消融过程。

9. 发明申请

WO2010120883A3 CARDIAC ABLATION CATHETERS FOR FORMING OVERLAPPING LESIONS 审中-公开
标题翻译：用于形成超重力的心脏吸收导管
公开(公告)号：WO2010120883A3
公开(公告)日：2011-03-24
申请号：PCT/US2010031034
申请日：2010-04-14
申请人： CARDIOFOCUS INC , MELSKY GERALD , SAGON STEPHEN W , STANCAMPIANO ALFRED , ARNOLD JEFFREY M , BAXTER LINCOLN S
发明人： MELSKY GERALD , SAGON STEPHEN W , STANCAMPIANO ALFRED , ARNOLD JEFFREY M , BAXTER LINCOLN S
IPC分类号： A61B18/24
CPC分类号： A61B18/245 , A61B2017/00057 , A61B2017/00061 , A61B2018/0097 , A61B2018/2261 , A61B2018/2266 , A61B2018/2272 , A61B2090/065 , A61N7/02
摘要： Methods and instruments are disclosed for creating lesions in tissue, especially cardiac tissue, for treatment of arrhythmias and the like, by employing an elastic balloon and an energy emitter, which is independently positionable within the lumen of the instrument and adapted to project a series of spots of ablative energy through a transmissive region of the balloon to a target tissue site. The energy emitter preferably is configured such the spots of energy result in a series of lesions formed in the target tissue region when the emitter is activated, the lesions having an average area ranging from about 5 mm2 to about 100 mm2. In one aspect of the invention, percutaneous ablation instruments are disclosed in the form of catheter bodies having one or more balloon structures at the distal end region of the instrument and an energy emitting element, which is independently positionable and rotatable within a lumen of the instrument and adapted to project ablative energy through a transmissive region of the balloon to a target tissue site in contact with, or proximal to, the balloon surface.
摘要翻译：公开了用于通过使用弹性球囊和能量发射器在组织，特别是心脏组织中产生病变以治疗心律失常等的方法和仪器，所述弹性球囊和能量发射器可独立地定位在所述仪器的内腔内并适于投射一系列通过球囊的透射区域到目标组织部位的烧蚀能量点。能量发射体优选配置成当发射器被激活时，这样的能量点会导致在靶组织区域中形成的一系列损伤，病变的平均面积范围为约5mm 2至约100mm 2。在本发明的一个方面，经皮消融器具以导管本体的形式被公开，所述导管主体在器械的远端区域具有一个或多个球囊结构，并且能量发射元件可独立地在仪器的内腔内定位和旋转并且适于将消融能量通过球囊的透射区域投射到与球囊表面接触或接近的目标组织部位。

10. 发明申请

WO2011025640A1 INTEGRATED FIBER OPTIC RAMAN SPECTROSCOPY AND RADIO FREQUENCY ABLATION 审中-公开
标题翻译：集成光纤光学拉曼光谱和无线电频率消除
公开(公告)号：WO2011025640A1
公开(公告)日：2011-03-03
申请号：PCT/US2010/044438
申请日：2010-08-04
申请人： NEW JERSEY INSTITUTE OF TECHNOLOGY , NIVER, Edip , LIEBERMAN, Kenneth, W.
发明人： NIVER, Edip , LIEBERMAN, Kenneth, W.
IPC分类号： A61B18/18
CPC分类号： A61B5/0075 , A61B1/00165 , A61B1/07 , A61B5/0084 , A61B5/0086 , A61B5/01 , A61B5/6847 , A61B18/1492 , A61B90/37 , A61B2017/00057 , A61B2017/00061 , A61B2017/00084 , A61B2018/00642 , A61B2018/00761 , A61B2018/00791 , A61B2018/00904 , A61B2090/306 , A61B2560/04
摘要： Technologies are generally described for detecting diseased tissues through fiber optic based Raman spectroscopy, image acquisition, and/or RF induced hyperthermia treatment of the detected tissues in an integrated manner. A fiber optic bundle for carrying optical and RF signals for the spectroscopy, visual imaging, and RF ablation may also be used to detect a temperature of the treated tissue such that level and duration of the RF signal can be controlled for optimum results. A shielding configuration in the form of a coaxial waveguide of the fiber optic bundle may be used to guide and deliver the RF signal. Sources and detectors for the optical and RF signals may be integrated into an endoscopic probe containing the fiber optic bundle or be externally positioned. An integrated or remote controller may be employed to manage the optical imaging, spectroscopy, RF ablation, and thermal sensing operations.
摘要翻译：通常描述技术以通过基于光纤的拉曼光谱，图像采集和/或RF诱导的热疗治疗检测到的组织以集成的方式检测患病组织。用于携带用于光谱，视觉成像和RF消融的光学和RF信号的光纤束也可以用于检测经处理的组织的温度，使得可以控制RF信号的水平和持续时间以获得最佳结果。可以使用光纤束的同轴波导形式的屏蔽配置来引导和传送RF信号。用于光学和RF信号的源和检测器可以集成到包含光纤束的内窥镜探针中或者被外部定位。可以使用集成或遥控器来管理光学成像，光谱学，RF消融和热感测操作。

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