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    • 4. 发明申请
    • METHODS OF REDUCING THE INHIBITORY EFFECT OF A REDOX ACTIVE METAL ION ON THE ENZYMATIC HYDROLYSIS OF CELLULOSIC MATERIAL
    • 减少氧化还原活性金属离子对纤维素材料酶解水解的抑制作用的方法
    • WO2009059234A3
    • 2009-06-18
    • PCT/US2008082127
    • 2008-10-31
    • NOVOZYMES INCXU FENG
    • XU FENG
    • C12P7/10C12P19/02
    • C12P7/10C12P19/02Y02E50/16
    • The present invention relates to methods of producing a cellulosic material reduced in a redox active metal cation having a redox potential (E°) in the range of about -0.4 to about 1.2 volts, comprising treating the cellulosic material with an effective amount of a chelator to reduce the inhibitory effect of the redox active metal cation on enzymatically degrading or converting the cellulosic material and alternatively also treating the cellulosic material with an effective amount of an oxidant when the redox active metal cation has a low valence state to convert the redox active metal cation to a high valence state to preferentially chelate the redox active metal cation. The present invention also relates to methods for degrading or converting a cellulosic material and to methods of producing a fermentation product.
    • 本发明涉及减少氧化还原电位(E°)在约-0.4至约1.2伏范围内的氧化还原活性金属阳离子中还原的纤维素材料的方法,包括用有效量的螯合剂处理纤维素材料 以减少氧化还原活性金属阳离子对酶促降解或转化纤维素材料的抑制作用,或者当氧化还原活性金属阳离子具有低价态以转化氧化还原活性金属时,用有效量的氧化剂处理纤维素材料 阳离子成高价态以优先螯合氧化还原活性金属阳离子。 本发明还涉及降解或转化纤维素材料的方法以及生产发酵产物的方法。