会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 3. 发明申请
    • METHOD AND APPARATUS FOR DETECTING AND COUNTING PLATELETS INDIVIDUALLY AND IN AGGREGATE CLUMPS
    • 用于检测和计数平板电脑的方法和装置
    • WO2009117682A1
    • 2009-09-24
    • PCT/US2009/037844
    • 2009-03-20
    • ABBOTT POINT OF CARE, INC.WARDLAW, Stephen C.LEVINE, Robert A.LALPURIA, Niten V.
    • WARDLAW, Stephen C.LEVINE, Robert A.LALPURIA, Niten V.
    • G01N33/50G01N33/49G01N15/02G01N15/14G01N33/80G01N33/58
    • G01N33/49G01N15/147G01N15/1475G01N2015/0076G01N2015/008G01N2015/0084G01N2015/0092G01N2015/1486
    • A method for enumerating platelets within a blood sample is provided. The method includes the steps of: 1) depositing the sample into an analysis chamber adapted to quiescently hold the sample for analysis, the chamber defined by a first panel and a second panel, both of which panels are transparent; 2) admixing a colorant with the sample, which colorant is operative to cause the platelets to fluoresce upon exposure to one or more predetermined first wavelengths of light; 3) illuminating at least a portion of the sample containing the platelets at the first wavelengths; 4) imaging the sample, including producing image signals indicative of fluorescent emissions from the platelets, which fluorescent emissions have an intensity; 5) identifying the platelets by their fluorescent emissions, using the image signals; 6) determining an average fluorescent emission intensity value for the individual platelets identified within the sample; 7) identifying clumps of platelets within the sample using one or more of their fluorescent emissions, area, shape, and granularity; and 8) enumerating platelets within each platelet clump using the average fluorescent emission intensity value determined for the individual platelets within the sample.
    • 提供了一种用于列举血液样品中的血小板的方法。 该方法包括以下步骤:1)将样品沉积到适于静态保持样品进行分析的分析室中,所述室由第一面板和第二面板限定,两个面板都是透明的; 2)将着色剂与样品混合,所述着色剂在暴露于一个或多个预定的第一波长的光时可以使血小板发荧光; 3)以第一波长照射含有血小板的样品的至少一部分; 4)对样品进行成像,包括产生指示来自血小板的荧光发射的图像信号,该荧光发射具有强度; 5)使用图像信号通过荧光发射识别血小板; 6)确定样品内识别的各个血小板的平均荧光发射强度值; 7)使用其荧光发射,面积,形状和粒度中的一种或多种来鉴定样品中的血小板团块; 和8)使用为样品中的各个血小板确定的平均荧光发射强度值来列举每个血小板聚集体内的血小板。
    • 4. 发明申请
    • PERFORMING ONE OR MORE ANALYSES ON A THIN LAYER OF BIOLOGIC FLUID USING OPTICALLY RESPONSIVE CHEMICAL SENSORS
    • 使用光学化学传感器在生物流体薄层上进行一个或多个分析
    • WO2017123296A1
    • 2017-07-20
    • PCT/US2016/056965
    • 2016-10-14
    • LEVINE, Robert A.WARDLAW, Stephen C.
    • LEVINE, Robert A.WARDLAW, Stephen C.
    • G01N15/14G01N21/29G01N21/76G01N21/77G01N33/00G01N33/48
    • G01N33/487G01N21/6428G01N21/6489G01N21/77G01N21/78G01N33/48G01N2021/6434G01N2021/7786
    • A method and apparatus for analyzing a biologic fluid sample for at least one target analyte is provided. The method includes providing an analysis chamber having at least one optically responsive chemical sensor (ORCS), sample and calibration fluid regions, and at least one fluid separator that separates the sample and calibration fluid regions. A first portion of each sensor is disposed in the sample fluid region and a second portion of each sensor is disposed in the calibration fluid region. The ORCS is configured to optically respond in the presence of the target analyte and when interrogated with one or more predetermined wavelengths oflight. The method further includes disposing at least one calibration fluid having target analyte in a known or ascertainable concentration in the calibration fluid region, and disposing the biologic fluid sample in the sample fluid region. The sample is analyzed using a first optical response from the first portion of the ORCS and a second optical response from the second portion of the ORCS.
    • 提供了用于分析至少一种目标分析物的生物流体样品的方法和设备。 该方法包括提供具有至少一个光学响应化学传感器(ORCS),样本和校准流体区域的分析室以及分离样本和校准流体区域的至少一个流体分离器。 每个传感器的第一部分布置在样本流体区域中,并且每个传感器的第二部分布置在校准流体区域中。 ORCS被配置为在存在目标分析物时以及在用一个或多个预定波长的光进行询问时进行光学响应。 该方法还包括将具有目标分析物的至少一种校准流体以已知或可确定的浓度设置在校准流体区域中,并且将生物流体样品设置在样品流体区域中。 使用来自ORCS的第一部分的第一光学响应和来自ORCS的第二部分的第二光学响应来分析样本。
    • 9. 发明申请
    • HARVESTING TARGET MATERIALS FROM CENTRIFUGED SUSPENSIONS
    • 从离心悬挂中收集目标材料
    • WO2010148135A2
    • 2010-12-23
    • PCT/US2010/038887
    • 2010-06-16
    • LEVINE, Robert A.WARDLAW, Stephen C.
    • LEVINE, Robert A.WARDLAW, Stephen C.
    • G01N33/483G01N1/28G01N35/10C12M1/10G01N1/14
    • G01N33/491Y10T436/25Y10T436/25375
    • Embodiments of the present invention are directed to harvesting a target material from a suspension using a tube and float system. A suspension suspected of containing a target material is combined with a solution having one or more labels that distinguish the target material from other materials in the suspension. The tube, float, and suspension are centrifuged to separate various materials in the suspension according to associated specific gravities. The float expands the axial length of the target material layer and displaces the target material to a narrow space between the float and the inner wall of the tube. The space is illuminated with light that causes the labels to emit light identifying the location of the target material within the tube. One or more openings can then be formed in the tube at or near the point where the target material is located and the target material harvested.
    • 本发明的实施方案涉及使用管和浮子系统从悬浮液中收获目标材料。 怀疑含有目标材料的悬浮液与具有一种或多种将目标材料与悬浮液中的其他材料区分开的标签的溶液合并。 将管,浮子和悬浮液离心以根据相关的比重分离悬浮液中的各种材料。 浮子膨胀目标材料层的轴向长度,并将目标材料移位到浮子和管内壁之间的狭窄空间。 该空间用光照亮,导致标签发光,以识别目标材料在管内的位置。 然后可以在管中或在目标材料所在的点处或附近形成一个或多个开口,并且收集目标材料。