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1. 发明申请

WO2010117969A2 MODULATED MULTI-FREQUENCY PROCESSING METHOD 审中-公开
标题翻译：调制多频处理方法
公开(公告)号：WO2010117969A2
公开(公告)日：2010-10-14
申请号：PCT/US2010/030019
申请日：2010-04-06
申请人： LAM RESEARCH CORPORATION , MARAKHTANOV, Alexei , HUDSON, Eric , DHINDSA, Rajinder , BAILEY, Andrew
发明人： MARAKHTANOV, Alexei , HUDSON, Eric , DHINDSA, Rajinder , BAILEY, Andrew
IPC分类号： H01L21/3065 , H05H1/24 , H05H1/36
CPC分类号： H01L21/3065 , H01J37/32009 , H01J37/32137 , H01J37/32146 , H01J2237/334 , H01J2237/3348
摘要： A method is provided for operating a processing system having a space therein arranged to receive a gas and an electromagnetic field generating portion operable to generate an electromagnetic field within the space. The method includes providing a gas into the space, and operating the electromagnetic field generating portion with a driving potential to generate an electromagnetic field within the space to transform at least a portion of the gas into plasma. The driving potential as a function of time is based on a first potential function portion and a second potential function portion. The first potential function portion comprises a first continuous periodic portion having a first amplitude and a first frequency. The second potential function portion comprises a second periodic portion having an maximum amplitude portion, and minimum amplitude portion and a duty cycle. The maximum amplitude portion is a higher amplitude than the minimum amplitude portion. The duty cycle is the ratio of a duration of the maximum amplitude portion to the sum of the duration of the maximum amplitude portion and the duration of the minimum amplitude portion. The second periodic portion additionally has a second frequency during the maximum amplitude portion. An amplitude modulation of the second periodic portion is phase locked to the first continuous periodic portion.
摘要翻译：提供了一种操作处理系统的方法，该处理系统具有布置成接收气体的空间和可操作以在该空间内产生电磁场的电磁场产生部分。所述方法包括向所述空间提供气体，以及利用驱动电位操作所述电磁场产生部分，以在所述空间内产生电磁场，以将所述气体的至少一部分转化为等离子体。作为时间的函数的驱动电位基于第一潜在功能部分和第二电位功能部分。第一潜在功能部分包括具有第一幅度和第一频率的第一连续周期部分。第二电位功能部分包括具有最大振幅部分和最小振幅部分和占空比的第二周期部分。最大幅度部分比最小振幅部分的幅度更大。占空比是最大幅度部分的持续时间与最大振幅部分的持续时间和最小振幅部分的持续时间之和的比率。第二周期部分在最大振幅部分期间另外具有第二频率。第二周期部分的幅度调制被锁相到第一连续周期部分。

2. 发明申请

WO2011026127A2 A LOCAL PLASMA CONFINEMENT AND PRESSURE CONTROL ARRANGEMENT AND METHODS THEREOF 审中-公开
标题翻译：局部等离子体约束和压力控制装置及其方法
公开(公告)号：WO2011026127A2
公开(公告)日：2011-03-03
申请号：PCT/US2010/047376
申请日：2010-08-31
申请人： LAM RESEARCH CORPORATION , DHINDSA, Rajinder , KELLOG, Mike , KADKODYAN, Babak , BAILEY, Andrew
发明人： DHINDSA, Rajinder , KELLOG, Mike , KADKODYAN, Babak , BAILEY, Andrew
IPC分类号： H05H1/46 , H01L21/3065 , C23C16/50
CPC分类号： H01J37/32642 , H01J37/32623
摘要： An arrangement for performing pressure control within a processing chamber substrate processing is provided. The arrangement includes a peripheral ring configured at least for surrounding a confined chamber volume that is configured for sustaining a plasma for etching the substrate during substrate processing. The peripheral ring includes a plurality of slots that is configured at least for exhausting processed byproduct gas from the confined chamber volume during substrate processing. The arrangement also includes a conductive control ring that is positioned next to the peripheral ring and is configured to include plurality of slots. The pressure control is achieved by moving the conductive control ring relative to the peripheral ring such that a first slot on the peripheral ring and a second slot on the conductive control ring are offset with respect to one another in a range of zero offset to full offset.
摘要翻译：提供了用于在处理腔室衬底处理内执行压力控制的布置。该装置包括外围环，该外围环被配置成至少用于围绕封闭室体积，该封闭室体积被配置为在衬底处理期间维持用于蚀刻衬底的等离子体。外围环包括多个槽，所述槽被配置为至少用于在衬底处理期间从封闭室体积中排出处理后的副产物气体。该装置还包括导电控制环，该导电控制环位于外围环旁边并被配置为包括多个槽。通过使导电控制环相对于外围环移动来实现压力控制，使得外围环上的第一槽和导电控制环上的第二槽在零偏移至全偏移的范围内相对于彼此偏移

3. 发明申请

WO2011028600A2 ARRANGEMENTS FOR MANIPULATING PLASMA CONFINEMENT WITHIN A PLASMA PROCESSING SYSTEM AND METHODS THEREOF 审中-公开
标题翻译：用于在等离子体处理系统中操纵等离子体约束的装置及其方法
公开(公告)号：WO2011028600A2
公开(公告)日：2011-03-10
申请号：PCT/US2010/046790
申请日：2010-08-26
申请人： LAM RESEARCH CORPORATION , JUCO, Eller, Y. , SHIN, Neungho , KIM, Yunsang , BAILEY, Andrew
发明人： JUCO, Eller, Y. , SHIN, Neungho , KIM, Yunsang , BAILEY, Andrew
IPC分类号： H01L21/3065
CPC分类号： H01J37/32183 , H01J37/32091 , H01J37/32541 , H01J37/32568 , H01J37/32706 , H01J2237/334
摘要： An arrangement for controlling bevel etch rate during plasma processing within a processing chamber. The arrangement includes a power source and a gas distribution system. The arrangement also includes a lower electrode, which is configured at least for supporting a substrate. The arrangement further includes a top ring electrode positioned above the substrate and a bottom ring electrode positioned below the substrate. The arrangement yet also includes a first match arrangement coupled to the top ring electrode and configured at least for controlling current flowing through the top ring electrode to control amount of plasma available for etching at least a part of the substrate top edge. The arrangement yet further includes a second match arrangement configured to control the current flowing through the bottom ring electrode to control amount of plasma available for at least etching at least a part of the substrate bottom edge.
摘要翻译：用于在处理室内的等离子体处理期间控制斜面蚀刻速率的布置。该装置包括电源和气体分配系统。该装置还包括至少用于支撑衬底的下电极。该装置还包括位于衬底上方的顶部环形电极和位于衬底下方的底部环形电极。该装置还包括第一匹配装置，其耦合到顶部环形电极并且至少用于控制流过顶部环形电极的电流，以控制可用于蚀刻衬底顶部边缘的至少一部分的等离子体的量。该装置还包括第二匹配装置，其被配置为控制流过底部环形电极的电流以控制可用于至少蚀刻衬底底部边缘的至少一部分的等离子体的量。

4. 发明申请

WO2012085583A1 NEW COMPOUND 审中-公开
标题翻译：新化合物
公开(公告)号：WO2012085583A1
公开(公告)日：2012-06-28
申请号：PCT/GB2011/052560
申请日：2011-12-22
申请人： ASTRAZENECA AB , PULMAGEN THERAPEUTICS (SYNERGY) LIMITED , ALCARAZ, Lilian , BAILEY, Andrew , KINDON, Nicholas
发明人： ALCARAZ, Lilian , BAILEY, Andrew , KINDON, Nicholas
IPC分类号： A61K31/425 , A61K31/535
CPC分类号： A61K31/425 , A61K31/535 , A61K45/06 , A61K2300/00
摘要： The invention provides a pharmaceutical product, kit or composition comprising a first active ingredient which is N-Butyl-N-(2-(2-(5-hydroxy-3-oxo-3,4-dihydro-2H- benzo[b][1,4]oxazin-8-yl)ethylamino)ethyl)-3-(3-(2-(4-(2-isopropylthiazole-4-carbonyl)-1-5 oxa-4,9-diazaspiro[5.5]undecan-9-yl)ethyl)phenethoxy)propanamide or a salt thereof, and a second active ingredient selected from: a non-steroidal Glucocorticoid Receptor (GR Receptor) Agonist; an antioxidant; a CCR1 antagonist; a chemokine antagonist (not CCR1); a corticosteroid; a CRTh2 antagonist; a DP1 antagonist; an Histone Deacetylase activator; an IKK2 kinase inhibitor; a COX inhibitor; a lipoxygenase inhibitor; a leukotriene receptor antagonist; an MPO inhibitor; a PDE4 inhibitor; a PPAR ϒ agonist; a protease inhibitor; a p38 inhibitor, a selective glucocorticoid receptor agonist (SEGRA), a Statin; a thromboxane antagonist; a vasodilator; or, an ENAC blocker (Epithelial Sodium-channel blocker); and its use in the treatment of respiratory disease.
摘要翻译：本发明提供了包含N-丁基-N-（2-（2-（5-羟基-3-氧代-3,4-二氢-2H-苯并[b] 乙基氨基）乙基）-3-（3-（2-（4-（2-异丙基噻唑-4-羰基）-1-氧代-4,9-二氮杂螺[5.5] 十一烷-9-基）乙基）苯乙氧基）丙酰胺或其盐，和第二活性成分，选自：非甾体糖皮质激素受体（GR受体）激动剂; 抗氧化剂 CCR1拮抗剂; 趋化因子拮抗剂（不是CCR1）; 皮质类固醇 CRTh2拮抗剂; DP1拮抗剂; 组蛋白脱乙酰酶激活剂; IKK2激酶抑制剂; COX抑制剂; 脂氧合酶抑制剂; 白细胞三烯受体拮抗剂; MPO抑制剂; PDE4抑制剂; 一个PPAR？激动剂; 蛋白酶抑制剂; p38抑制剂，选择性糖皮质激素受体激动剂（SEGRA），他汀类药物; 血栓素拮抗剂; 血管扩张剂或ENAC阻断剂（上皮钠通道阻断剂）; 并用于治疗呼吸系统疾病。

5. 发明申请

WO2004000825A1 NOVEL COMPOUNDS 审中-公开
标题翻译：新型化合物
公开(公告)号：WO2004000825A1
公开(公告)日：2003-12-31
申请号：PCT/SE2003/001080
申请日：2003-06-23
申请人： ASTRAZENECA AB , BAILEY, Andrew , PAIRAUDEAU, Garry , PATEL, Anil , THOM, Stephen
发明人： BAILEY, Andrew , PAIRAUDEAU, Garry , PATEL, Anil , THOM, Stephen
IPC分类号： C07D295/182
CPC分类号： C07D295/185 , A61K31/472 , A61K31/495 , A61K31/5375 , C07D211/66 , C07D217/06 , C07D309/14
摘要： The present invention relates to compounds and compositions for treating diseases associated with cysteine protease activity. The compounds are reversible inhibitors of cysteine proteases S, K, F, L and B. Of particular interest are diseases associated with Cathepsin S. In addition this invention also discloses processes for the preparation of such inhibitors. (I) in which: A is a 6-membered ring optionally containing a double bond and optionally containing an oxygen atom or NR group in the ring;
摘要翻译：本发明涉及用于治疗与半胱氨酸蛋白酶活性相关的疾病的化合物和组合物。这些化合物是半胱氨酸蛋白酶S，K，F，L和B的可逆抑制剂。特别有意义的是与组织蛋白酶S相关的疾病。此外，本发明还公开了制备这种抑制剂的方法。（I）其中：A是任选地含有双键并任选地在环中含有氧原子或NR基团的6元环;

6. 发明申请

WO2009106867A1 AN INSTRUMENT FOR USE IN A JOINT REPLACEMENT PROCEDURE 审中-公开
标题翻译：在联合更换程序中使用的仪器
公开(公告)号：WO2009106867A1
公开(公告)日：2009-09-03
申请号：PCT/GB2009/050112
申请日：2009-02-05
申请人： DePuy International Ltd , BAILEY, Andrew , GOWERS, Steven
发明人： BAILEY, Andrew , GOWERS, Steven
IPC分类号： A61F2/40
CPC分类号： A61F2/4684 , A61F2/4637 , A61F2/4657 , A61F2002/365 , A61F2002/4037 , A61F2002/4658
摘要： An instrument for use in a joint replacement procedure. The instrument comprises a trial head (162) which corresponds to the head of an orthopaedic joint component having an upper surface defined by a curved surface and a bore formed in a lower surface. The instrument further comprises a trial connector (164) for connecting the trial head (162) to a stem part (12) of the orthopaedic joint component which is intended for location in the intramedullary cavity of a bone. The trial connector (164) can be fitted into the bore in the trial head (162) at a variable angular orientation. The instrument further comprises a rotating indicator (174) pivo tally coupled about a polar axis of the trial head (162) which is defined by the curved upper surface, the rotating indicator (174) being coupled to the trial connector (164) such that the rotational position of the rotating indicator (174) about the polar axis is indicative of the rotational position of the trial connector (164) within the bore in the trial head (162). The bore in the lower surface of the trial head (162) is eccentric of the polar axis and the connection between the trial connector (164) and the stem part (12) of the orthopaedic joint component is eccentric of the centre of the trial connector (164). A predetermined point on the rotating indicator (174) is indicative of the direction of maximum eccentricity of the trial head (162) relative to the connection between the trial connector (164) and the stem (12) of the orthopaedic component. Also disclosed is an assembly which comprises the instrument and an orthopaedic joint component which comprises a head part (20), a stem part (12) and a connector sleeve part (30).
摘要翻译：用于关节置换手术的仪器。仪器包括试验头（162），其对应于具有由弯曲表面限定的上表面的骨科关节部件的头部和形成在下表面中的孔。仪器还包括用于将试验头（162）连接到用于定位在骨髓内腔中的整形外科关节部件的杆部分（12）的试验连接器（164）。试验连接器（164）可以以可变的角度方向装配在试验头（162）中的孔中。该仪器还包括旋转指示器（174），其围绕由弯曲的上表面限定的试用头（162）的极轴枢转耦合，旋转指示器（174）联接到试用连接器（164），使得旋转指示器（174）围绕极轴的旋转位置指示试用连接器（164）在试验头（162）的孔内的旋转位置。试验头（162）的下表面中的孔是极轴的偏心，并且试验连接器（164）与矫形接头部件的杆部（12）之间的连接是试验连接器中心的偏心（164）。旋转指示器（174）上的预定点指示试验头（162）相对于试验连接器（164）和矫形部件的杆（12）之间的连接的最大偏心度的方向。还公开了一种组件，其包括仪器和整形外科接头部件，其包括头部（20），杆部（12）和连接器套筒部（30）。

7. 发明申请

WO2004000819A1 NEW USE OF PYRIMIDINE - OR TRIAZINE- 2-CARBONITILES FOR TREATING DISEASES ASSOCIATED WITH CYSTEINE PROTEASE ACTIVITY AND NOVEL PYRIMIDINE-2-CARBONITILE DERIVATIVES 审中-公开
标题翻译：新亚利辛 - 或二噻二碳二烯的新用途，用于治疗与CYSTEINE PROTEASE活性相关的疾病和新型的嘧啶-2-羰基衍生物
公开(公告)号：WO2004000819A1
公开(公告)日：2003-12-31
申请号：PCT/SE2003/001078
申请日：2003-06-23
申请人： ASTRAZENECA AB , BAILEY, Andrew , PAIRAUDEAU, Garry , PATEL, Anil , THOM, Stephen
发明人： BAILEY, Andrew , PAIRAUDEAU, Garry , PATEL, Anil , THOM, Stephen
IPC分类号： C07D239/24
CPC分类号： C07D239/47 , A61K31/506 , A61K31/53 , C07D239/48 , C07D239/50 , C07D251/18 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D405/12 , C07D413/14 , C07D487/08
摘要： The present invention therefore provides use of a compound of formula (I) and compositions for treating diseases associated with cysteine protease activity. The compounds are reversible inhibitors of cysteine proteases S, K, F, L and B. Of particular interest are diseases associated with Cathepsin S. In addition, this invention also discloses processes for the preparation of such inhibitors.
摘要翻译：因此，本发明提供式（I）化合物和组合物用于治疗与半胱氨酸蛋白酶活性相关的疾病的用途。这些化合物是半胱氨酸蛋白酶S，K，F，L和B的可逆抑制剂。特别关注的是与组织蛋白酶S相关的疾病。此外，本发明还公开了制备这种抑制剂的方法。

8. 发明申请

WO2015044680A1 AN INSTRUMENT FOR POSITIONING A CUP COMPONENT OF AN ORTHOPAEDIC JOINT PROSTHESIS 审中-公开
标题翻译：用于定位正交联合检测的杯子组件的仪器
公开(公告)号：WO2015044680A1
公开(公告)日：2015-04-02
申请号：PCT/GB2014/052928
申请日：2014-09-29
申请人： DEPUY (IRELAND) , BAILEY, Andrew
发明人： BAILEY, Andrew
IPC分类号： A61F2/46 , A61F2/34
CPC分类号： A61F2/4609 , A61F2/34 , A61F2002/30484 , A61F2002/30579 , A61F2002/4623 , A61F2002/4627 , A61F2002/4628
摘要： An instrument (102) for positioning a cup component (104) of an orthopaedic joint prosthesis is described. The instrument includes an actuator (124) and a plurality of jaw members (152, 154, 156, 158) around a longitudinal axis. Each jaw member includes a mounting end (162), a gripping end (166) and a surface (174) between them. The gripping end has a transversely extending member (168) which can be received in a recess in a wall of a cup component and can displaced between a retracted position and a deployed position. The surface is inclined to the longitudinal axis of the instrument and curved in an outward direction away from the longitudinal axis. The actuator and the plurality of jaw members are capable of relative movement along the longitudinal axis of the instrument with the actuator in contact with the inclined surfaces of the jaw members so that said relative movement causes the jaw members to move between their retracted position and deployed position.
摘要翻译：描述了用于定位整形外科关节假体的杯部件（104）的器械（102）。仪器包括致动器（124）和围绕纵向轴线的多个钳口构件（152,154,156,158）。每个钳口构件包括安装端（162），夹持端（166）和它们之间的表面（174）。夹持端具有横向延伸构件（168），该构件可以容纳在杯部件的壁中的凹部中并且能够在缩回位置和展开位置之间移动。该表面相对于仪器的纵向轴线倾斜，并且沿远离纵轴的向外的方向弯曲。致动器和多个钳口构件能够沿着仪器的纵向轴线相对运动，致动器与钳口构件的倾斜表面接触，使得所述相对运动使得钳口构件在其缩回位置和部署之间移动位置。

9. 发明申请

WO2007027134A1 7-(2-AMINO-1-HYDROXY-ETHYL)-4-HYDROXYBENZOTHIAZOL-2(3H)-ONE-DERIVATIVES AS β2 ADRENOCEPTOR AGONISTS 审中-公开
标题翻译： 7-（2-氨基-1-羟基 - 乙基）-4-羟基苯并噻唑-2（3H） - 酮衍生物作为β2ADRENOCEPTOR AGONISTS
公开(公告)号：WO2007027134A1
公开(公告)日：2007-03-08
申请号：PCT/SE2006/000981
申请日：2006-08-28
申请人： ASTRAZENECA AB , BAILEY, Andrew , BONNERT, Roger , CONNOLLY, Stephen , INGALL, Anthony , PAIRAUDEAU, Garry , STOCKS, Michael
发明人： BAILEY, Andrew , BONNERT, Roger , CONNOLLY, Stephen , INGALL, Anthony , PAIRAUDEAU, Garry , STOCKS, Michael
IPC分类号： C07D277/68 , A61K31/428 , A61P11/00 , A61P11/06
CPC分类号： C07D277/68
摘要： The present invention provides compounds of formula (I) wherein the variables are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
摘要翻译：本发明提供式（I）化合物，其中变量如本说明书中所定义，其制备方法，含有它们的药物组合物及其在治疗中的用途。

10. 发明申请

WO2015124912A1 SURGICAL INSTRUMENT 审中-公开
标题翻译：手术器械
公开(公告)号：WO2015124912A1
公开(公告)日：2015-08-27
申请号：PCT/GB2015/050445
申请日：2015-02-17
申请人： DEPUY (IRELAND) , BAILEY, Andrew , BROOKS, James
发明人： BAILEY, Andrew , BROOKS, James
IPC分类号： A61B17/15
CPC分类号： A61B17/15 , A61B17/154 , A61B17/155 , A61B2017/00862
摘要： A cutting block (1) for fixing relative to a bone for guiding a saw blade during a step in an orthopaedic surgical procedure in which the bone is cut, comprises a body (2) having a top surface (6) for guiding a saw blade, and a top plate (3) which is connected to the body and which can move between a first position in which the top plate is spaced apart from the body and a second position in which the top surface of the top plate is contiguous with and an extension of the top surface of the body. The top plate has first and second resiliently deformable arms (15, 16) extending from it, spaced apart along the top plate, and the body has first and second recesses formed in it extending substantially perpendicularly to the top surface of the body. The first and second arms on the top plate are inserted in respective ones of the recesses so that the arms and the recesses define the path for movement of the top plate relative to the body between the first and second position. Each of the recesses has a profiled surface against which the respective deformable arm acts during movement of the top plate relative to the body between the first and second positions so as to cause the arm to deform, the deformation of each of the arms being greater when the top plate is in an intermediate position between the first and second positions than when it is in each of the first and second positions, so that the top plate is biased away from the intermediate position towards the first and second positions. Biasing of the arms to the first and second positions locks the top plate in either the first or second positions. The cutting block has the advantage of easier manufacturing, particularly as the numbers of components is reduced. Furthermore, it reduces the need for welding with the attendant heat distortion that can affect the final product. The cutting block is also easier to clean.
摘要翻译：用于在骨头被切割的整形外科手术中的步骤期间相对于骨头固定的用于引导锯片的切割块（1）包括具有用于引导锯片的顶表面（6）的主体（2），以及顶板（3），其连接到所述主体并且可以在其中所述顶板与所述主体间隔开的第一位置和所述顶板的顶表面邻接的第二位置和身体顶面的延伸。顶板具有从其延伸的第一和第二可弹性变形的臂（15,16），其沿着顶板间隔开，并且主体具有形成在其中的第一和第二凹部，其基本上垂直于主体的顶部表面延伸。顶板上的第一和第二臂被插入相应的凹槽中，使得臂和凹槽限定用于顶板相对于主体在第一和第二位置之间运动的路径。每个凹部具有成型表面，相应的可变形臂在顶板相对于本体在第一和第二位置之间运动期间作用，以使臂变形，每个臂的变形较大，当顶板位于第一位置和第二位置之间的中间位置，而不是位于第一位置和第二位置中的每一个位置，使得顶板偏离中间位置朝着第一和第二位置。将臂偏置到第一和第二位置将顶板锁定在第一或第二位置。切割块具有制造容易的优点，特别是随着部件数量的减少。此外，它减少了对可能影响最终产品的伴随的热变形的焊接需求。切割块也更容易清洁。

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