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1. 发明申请

WO2008026141A2 REDUCTION OF HEART MOTION ARTIFACTS IN THORACIC CT IMAGING 审中-公开
标题翻译：减少心脏CT成像中心脏运动的影响
公开(公告)号：WO2008026141A2
公开(公告)日：2008-03-06
申请号：PCT/IB2007/053403
申请日：2007-08-27
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BARSCHDORF, Hans , VON BERG, Jens , KUHN, Michael, H. , LORENZ, Cristian , BLAFFERT, Thomas
发明人： BARSCHDORF, Hans , VON BERG, Jens , KUHN, Michael, H. , LORENZ, Cristian , BLAFFERT, Thomas
IPC分类号： G06T7/20 , A61B5/00
CPC分类号： G06T7/251 , G06T7/149 , G06T7/33 , G06T2200/04 , G06T2207/10081 , G06T2207/30048 , G06T2207/30061 , G06T2211/412
摘要： The invention relates to a system (100) for adapting a plurality of model meshes to a plurality of image data, the system comprising a registration unit (110) for registering the plurality of model meshes with the plurality of image data on the basis of a computation of a registration transformation for transforming the plurality of model meshes, and an adaptation unit (120) for adapting the plurality of registered model meshes to the plurality of image data on the basis of a computation of locations of mesh vertices of the plurality of model meshes. The system (100) may further comprise a computing unit (130) for computing sparse vector fields comprising vectors of displacements of vertices of the adapted model meshes, an approximation unit (140) for computing dense vector fields on the basis of the sparse vector fields, a merge unit (150) for merging image data sets by means of the computed dense vector fields, and a reconstruction unit (155) for reconstructing a motion-compensated image data from the computed dense vector fields. The described system (100) is capable of reducing motion artifacts in tomographic images computed from data acquired at a plurality of different cardiac cycle phases.
摘要翻译：本发明涉及一种用于将多个模型网格适配到多个图像数据的系统（100），该系统包括登记单元（110），用于基于多个图像数据向多个图像数据登记多个模型网格用于变换多个模型网格的注册变换的计算;以及适应单元，用于根据多个模型的网格顶点的位置的计算来将多个注册模型网格适配到多个图像数据网格。系统（100）还可以包括计算单元（130），用于计算包括适应模型网格的顶点位移矢量的稀疏矢量场，用于基于稀疏矢量场计算密集矢量场的近似单元（140），用于通过所计算的密集矢量场合并图像数据组的合并单元（150），以及用于从所计算的密集矢量场重构运动补偿图像数据的重建单元（155）。所描述的系统（100）能够减少从在多个不同的心动周期阶段获取的数据计算的断层图像中的运动伪影。

2. 发明申请

WO2010086776A1 SYSTEM FOR PROVIDING LUNG VENTILATION INFORMATION 审中-公开
标题翻译：提供肺通气信息的系统
公开(公告)号：WO2010086776A1
公开(公告)日：2010-08-05
申请号：PCT/IB2010/050305
申请日：2010-01-25
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KABUS, Sven , OPFER, Roland , CARLSEN, Ingwer, C. , RENISCH, Steffen , SABCZYNSKI, Joerg , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , KLINDER, Tobias , LORENZ, Cristian , SCHADEWALDT, Nicole
发明人： KABUS, Sven , OPFER, Roland , CARLSEN, Ingwer, C. , RENISCH, Steffen , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , KLINDER, Tobias , LORENZ, Cristian , SCHADEWALDT, Nicole
IPC分类号： A61B5/08 , A61B6/03 , G06T7/00
CPC分类号： A61B6/5235 , A61B5/08 , A61B6/541 , G06T7/33 , G06T2207/10081 , G06T2207/30061
摘要： A system for displaying lung ventilation information, the system comprising an input (12) and a processing unit (15). The input being provided for receiving multiple CT images (71) of a lung, each CT image (71) corresponding to one phase of at least two different phases in a respiratory cycle. The processing unit (15) being configured to compare CT images (71) corresponding to different phases in the respiratory cycle for determining a deformation vector field for each phase, to generate for each phase a ventilation image (72) based on the corresponding deformation vector field, to spatially align the ventilation images (72), and to generate for at least one common position (62) in each one of the aligned ventilation images (72), a function (81) of a time course of a ventilation value for said common position (62), each ventilation value in the function (81) being based on the deformation vector fields corresponding to the aligned ventilation images (73).
摘要翻译：一种用于显示肺通气信息的系统，所述系统包括输入（12）和处理单元（15）。所述输入被提供用于接收肺的多个CT图像（71），每个CT图像（71）对应于呼吸周期中的至少两个不同相的一个相。所述处理单元（15）被配置为比较对应于呼吸周期中的不同相位的CT图像（71），以确定每个相位的变形矢量场，以根据相应的变形矢量为每个阶段生成通气图像（72）在空间上对准通气图像（72），并且为每个对齐的通气图像（72）中的至少一个公共位置（62）产生功能（81），其中通风值的时间过程为所述公共位置（62）中，所述功能（81）中的每个换气值基于对应于对齐的通气图像（73）的变形矢量场。

3. 发明申请

WO2009101560A2 APPARATUS FOR SEGMENTING AN OBJECT COMPRISING SUB-OBJECTS 审中-公开
标题翻译：用于分配包含子对象的对象的设备
公开(公告)号：WO2009101560A2
公开(公告)日：2009-08-20
申请号：PCT/IB2009/050495
申请日：2009-02-06
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BLAFFERT, Thomas , BARSCHDORF, Hans , VON BERG, Jens , DRIES, Sebastian, P., M. , LORENZ, Cristian , WIEMKER, Rafael , KLINDER, Tobias , FRANZ, Astrid, R. , RENISCH, Steffen
发明人： BLAFFERT, Thomas , BARSCHDORF, Hans , VON BERG, Jens , DRIES, Sebastian, P., M. , LORENZ, Cristian , WIEMKER, Rafael , KLINDER, Tobias , FRANZ, Astrid, R. , RENISCH, Steffen
IPC分类号： G06T7/00 , A61B5/00
CPC分类号： G06T5/003 , G06T7/11 , G06T7/149 , G06T2207/10081 , G06T2207/20041 , G06T2207/20081 , G06T2207/20124 , G06T2207/20192 , G06T2207/30061
摘要： The present invention relates to an apparatus (1) for segmenting an object comprising sub-objects shown in an object image. The apparatus comprises a feature image generation unit (2) for generating a feature image showing features related to intermediate regions between the sub-objects and a segmentation unit (3) for segmenting the sub-objects by using the object image and the feature image. Preferentially, the feature image generation unit (2) is adapted for generating a feature image from the object image. In a further embodiment, the feature image generation unit (2) comprises a feature enhancing unit for enhancing features related to intermediate regions between the sub-objects in the object image.
摘要翻译：本发明涉及一种用于分割包含物体图像中所示的子对象的物体的装置（1）。该装置包括：特征图像生成单元，用于生成显示与子对象之间的中间区域相关的特征的特征图像和用于通过使用对象图像和特征图像来分割子对象的分割单元（3）。优选地，特征图像生成单元（2）适于从对象图像生成特征图像。在另一实施例中，特征图像生成单元（2）包括特征增强单元，用于增强与对象图像中的子对象之间的中间区域相关的特征。

4. 发明申请

WO2008065590A1 IMPROVED SEGMENTATION 审中-公开
标题翻译：改进分类
公开(公告)号：WO2008065590A1
公开(公告)日：2008-06-05
申请号：PCT/IB2007/054751
申请日：2007-11-22
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , LORENZ, Cristian , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , DRIES, Sebastian, P., M , KABUS, Sven
发明人： LORENZ, Cristian , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , DRIES, Sebastian, P., M , KABUS, Sven
IPC分类号： G06T5/00
CPC分类号： G06T7/149 , G06T7/11 , G06T2207/10072 , G06T2207/30048
摘要： A computer program product is described to adapt a shape model to a patient data set, the data set representing at least a region of anatomy of the patient, and in which the shape model is pre-adapted to a data set representing substantially the same anatomy of the same patient. This provides a surprisingly better segmentation of the data in the data set. In addition, A computer program product is described for the comparison of quantitative patient data and arranged to access quantitative patient data contained in a patient data record, characterized in that the quantitative patient data is in the form of an adapted shape model, adapted from a pre-adapted shape model. This extends the improvement derived by use of pre-adapted shape models and extends them to the use of pre-adapted shape models for data comparison.
摘要翻译：描述了计算机程序产品以将形状模型适应于患者数据集，所述数据集表示至少一个患者的解剖结构的区域，并且其中形状模型预先适应于表示基本上相同的解剖结构的数据集的同一病人。这为数据集中的数据提供了令人惊奇的更好的分割。另外，计算机程序产品被描述为用于比较定量患者数据并被安排用于访问包含在患者数据记录中的定量患者数据，其特征在于定量患者数据是适应形状模型的形式，预适应形状模型。这扩展了通过使用预先调整的形状模型得到的改进，并将其扩展到使用预先调整的形状模型进行数据比较。

5. 发明申请

WO2008065585A3 IMPROVED PATIENT DATA RECORD AND USER INTERFACE 审中-公开
公开(公告)号：WO2008065585A3
公开(公告)日：2008-06-05
申请号：PCT/IB2007/054740
申请日：2007-11-22
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , LORENZ, Cristian , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , DRIES, Sebastian, P., M. , KABUS, Sven
发明人： LORENZ, Cristian , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , DRIES, Sebastian, P., M. , KABUS, Sven
IPC分类号： G06F19/00
摘要： A patient data record is described comprising a mean model representative of the patient and further comprises at least one shape model to represent data concerning the patient, in which the said mean model comprises at least one region and the said shape model comprises at least one sub-section, and in which the at least one sub-section of the shape model is linked to the equivalent region of the mean model. This has the advantage of allowing greater structure to the patient record. Further a system is described to present patient data upon queries generated by a user and arranged to access the claimed patient data record, and which is further arranged to provide access to information in the sub-section of the shape model when a query generated by the user accesses the equivalent region of the mean model. This system allows full use of the improved patient data record.

6. 发明申请

WO2010035183A2 PATIENT SPECIFIC ANATOMICAL SKETCHES FOR MEDICAL REPORTS 审中-公开
标题翻译：患者特殊解剖医学报告草图
公开(公告)号：WO2010035183A2
公开(公告)日：2010-04-01
申请号：PCT/IB2009/054070
申请日：2009-09-17
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , LORENZ, Cristian , DRIES, Sebastian, P., M. , RENISCH, Steffen , VON BERG, Jens
发明人： LORENZ, Cristian , DRIES, Sebastian, P., M. , RENISCH, Steffen , VON BERG, Jens
IPC分类号： G06T17/00
CPC分类号： G06F19/3487 , G06F19/00 , G06F19/321 , G06T7/0012 , G06T7/12 , G06T7/149 , G06T19/20 , G06T2207/10072 , G06T2207/10116 , G06T2207/30012 , G06T2219/2021 , G16H15/00
摘要： The invention relates to a system (100) for producing a representation of an object in image data, based on a template coupled to a model of the object, the system comprising a model unit for adapting the model to the object in the image data, and a template unit for adapting the template to the adapted model on the basis of the coupling between the template and the model. The template defines a representation of the object which is simpler to interpret than the model. The template may be arranged to emphasize useful features of the object. The template comprises substantially fewer degrees of freedom and thus can be efficiently adapted to the model. Because the template of the invention is coupled to the model, the position, orientation and/or shape of the template is determined by the model adapted to the object in the image data. Hence, the template is adapted to the image data. The adapted template is capable of representing the object and its individual characteristics, e.g., the shape of the object as well as the position and/or orientation of the object with respect to an external reference system defined, e.g., based on the image data.
摘要翻译：本发明涉及一种用于基于耦合到对象模型的模板来产生图像数据中的对象的表示的系统（100），该系统包括用于使模型适应图像数据中的对象的模型单元，以及模板单元，用于基于模板和模型之间的耦合来将模板适配到适配模型。模板定义了比模型更简单的对象的表示。模板可以被布置为强调对象的有用特征。该模板包括基本上更少的自由度，因此可以有效地适应于该模型。因为本发明的模板耦合到模型，所以模板的位置，取向和/或形状由适于图像数据中的对象的模型确定。因此，该模板适合图像数据。适应的模板能够表示对象及其各自的特征，例如对象的形状以及对象相对于例如基于图像数据定义的外部参考系统的位置和/或取向。

7. 发明申请

WO2009063363A2 COMPUTER-AIDED DETECTION (CAD) OF A DISEASE 审中-公开
标题翻译：一种疾病的计算机辅助检测（CAD）
公开(公告)号：WO2009063363A2
公开(公告)日：2009-05-22
申请号：PCT/IB2008/054632
申请日：2008-11-06
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , LORENZ, Cristian , VON BERG, Jens , BUELOW, Thomas , WIEMKER, Rafael
发明人： LORENZ, Cristian , VON BERG, Jens , BUELOW, Thomas , WIEMKER, Rafael
IPC分类号： G06T7/00
CPC分类号： G06T7/0012 , G06T7/11 , G06T2200/24 , G06T2207/10072 , G06T2207/30061
摘要： The present invention relates to a method for performing computer-aided detection (CAD) of a disease, e.g. lung tumours, on a medical image data set (20) from a imaging modality, such as MRI or CT. Initially, there is perform a segmentation of the medical image data set (20) using an anatomical model. Secondly, the segmented data is analyzed for characteristics of the disease resulting in a set of analysis data (25), and finally the set of analysis data (25) is evaluating with respect to the disease. At least one of these steps comprises as an input a position dependent probability (P_r) for the disease. The invention isadvantageous in that more efficient computations can be performed because the degree ofanalysis in a certain region of the part of the patient, e.g. the lung, can be adjusted or tailored to the level of probability of the disease in the that region. It is thereby possible to increase computational speed and thereby diseases like cancer, in particular cancer nodules in the lungs, can be more effectively found from medical image analysis.
摘要翻译：用于执行疾病的计算机辅助检测（CAD）的方法技术领域本发明涉及用于执行疾病的计算机辅助检测（CAD）的方法。（例如MRI或CT）的医学图像数据组（20）上的肺肿瘤。最初，使用解剖模型执行医学图像数据集（20）的分割。其次，对分段数据进行分析，以获得一组分析数据（25），最后分析数据集（25）针对该疾病进行评估。这些步骤中的至少一个包括疾病的位置依赖概率（P_r）作为输入。本发明的有利之处在于可以进行更有效的计算，因为患者部分的某个区域的分析程度，例如，肺，可以调整或适应该地区疾病的概率水平。因此可以提高计算速度，从而可以从医学图像分析中更加有效地发现诸如癌症的疾病，特别是肺部的癌症结节。

8. 发明申请

WO2008075259A3 TEMPORAL REGISTRATION OF MEDICAL DATA 审中-公开
公开(公告)号：WO2008075259A3
公开(公告)日：2008-06-26
申请号：PCT/IB2007/055054
申请日：2007-12-12
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , VON BERG, Jens , LORENZ, Cristian
发明人： VON BERG, Jens , LORENZ, Cristian
IPC分类号： G06T7/00
摘要： A data structure for use by a computer system for comparing temporally varying medical data (9a, 9b) is disclosed. The data structure performs the steps of receiving a first data set (9a) including first data representing a medical parameter at a plurality of first times, receiving a second data set (9b) including second data representing said medical parameter at a plurality of second times, and processing said first and/or second data sets to increase a degree of correlation or similarity between a plurality of said first and second times representing identifiable events.

9. 发明申请

WO2008010134A2 A METHOD, APPARATUS, SYSTEM AND COMPUTER-READABLE MEDIUM FOR INTERACTIVE SHAPE MANIPULATION 审中-公开
标题翻译：用于互动形状操作的方法，装置，系统和可计算机可读介质
公开(公告)号：WO2008010134A2
公开(公告)日：2008-01-24
申请号：PCT/IB2007/052658
申请日：2007-07-06
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , LORENZ, Cristian , RENISCH, Steffen , VON BERG, Jens
发明人： LORENZ, Cristian , RENISCH, Steffen , VON BERG, Jens
IPC分类号： G06T17/40
CPC分类号： G06F3/04845 , G06F19/321 , G06T19/20 , G06T2210/41 , G06T2219/2021 , G16H50/50
摘要： A method and apparatus for interactively manipulating a shape of an object, comprising selecting an object to be manipulated and rendering the object in dependence of a manipulation type. The method provides a smart object adapted interaction, manipulation and visualization scheme in contrast to previous display driven schemes. The method allows efficient shape manipulation by restricting the degrees of freedom for the manipulation to the meaningful ones for a given object or object part, thus allowing to reduce e.g. a 3D interaction to a 2D interaction.
摘要翻译：一种用于交互地操纵对象的形状的方法和装置，包括根据操作类型来选择要操纵的对象和呈现所述对象。与先前的显示驱动方案相比，该方法提供了一种智能对象适应的交互，操纵和可视化方案。该方法允许通过将用于操作的自由度限制到给定对象或对象部分的有意义的自由度来实现有效的形状操纵，从而允许减少例如与2D交互的3D交互。

10. 发明申请

WO2008004171A2 PREDICTION OF CARDIAC SHAPE BY A MOTION MODEL 审中-公开
标题翻译：运动模型预测心脏形态
公开(公告)号：WO2008004171A2
公开(公告)日：2008-01-10
申请号：PCT/IB2007/052559
申请日：2007-07-02
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N.V. , VON BERG, Jens , LORENZ, Cristian
发明人： VON BERG, Jens , LORENZ, Cristian
IPC分类号： G06T7/00 , G06T7/20 , A61B5/00
CPC分类号： G06T7/33 , G06T7/20 , G06T2207/10072 , G06T2207/30048
摘要： The invention relates to a system (100) for propagating a model mesh based on a first mean model mesh and on a second mean model mesh, the system comprising: a registration unit (110) for computing a registration transformation for registering the first model mesh with the first mean model mesh; a forward transformation unit (120) for transforming the model mesh into a registered model mesh using the registration transformation; a computation unit (130) for computing a propagation field for propagating the registered model mesh, the propagation field comprising vectors of displacements of vertices of the second mean model mesh relative to respective vertices of the first mean model mesh; a propagation unit (140) for transforming the registered model mesh into the propagated registered model mesh based on applying the vertex displacement vectors comprised in the propagation field to respective vertices of the registered model mesh; and an inverse transformation unit (150) for transforming the propagated registered model mesh into the propagated model mesh using the inverse of the registration transformation, thereby propagating the model mesh. Using the propagation field comprising vectors of displacements of vertices of the second mean model mesh relative to respective vertices of the first mean model mesh improves modeling motion of anatomical shapes. Advantageously, the propagation field of vertex displacement vectors is straightforward to compute and to apply.
摘要翻译：本发明涉及一种用于基于第一平均模型网格和第二平均模型网格传播模型网格的系统（100），该系统包括：注册单元（110），用于计算用于注册第一模型网格的注册变换用第一个平均模型网格; 用于使用所述注册变换将模型网格变换为注册模型网格的正向变换单元（120）计算单元（130），用于计算用于传播所述注册的模型网格的传播场，所述传播场包括相对于所述第一平均模型网格的相应顶点的所述第二平均模型网格的顶点的位移的向量; 传播单元，用于通过将包含在传播场中的顶点位移矢量应用于注册的模型网格的各顶点，将登记的模型网格变换为传播的注册模型网格; 以及逆变换单元（150），用于使用所述配准变换的逆来将所述传播的注册模型网格变换为所述传播的模型网格，从而传播所述模型网格。使用包括第二平均模型网格的顶点的位移矢量相对于第一平均模型网格的各个顶点的传播场改进了解剖形状的建模运动。有利地，顶点位移矢量的传播场是直接计算和应用的。

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