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    • 1. 发明申请
    • INJECTOR ASSEMBLIES AND MICROREACTORS INCORPORATING THE SAME
    • 注射器组件和微型计算机
    • WO2009110990A1
    • 2009-09-11
    • PCT/US2009/001265
    • 2009-02-27
    • CORNING INCORPORATEDLOBET, OlivierPOISSY, StephaneWOEHL, Pierre
    • LOBET, OlivierPOISSY, StephaneWOEHL, Pierre
    • B01F13/02
    • B01J19/0093B01F3/0446B01F5/0077B01F5/045B01J4/002B01J2219/0081B01J2219/0086B01J2219/00891B05B7/0433
    • A microreactor assembly (100) is provided comprising a fluidic microstructure (10) and an injector assembly (20). The injector assembly (20) comprises a liquid inlet (22), a gas inlet (24), a liquid outlet (26), a gas outlet (28), a liquid flow portion (30) extending from the liquid inlet (22) to the liquid outlet (26), and a gas flow portion (40) extending from the gas inlet (24) to the gas outlet (28). Further, the injector assembly (20) defines an injection interface with a microchannel input port (14) of the fluidic microstructure (10). The injector assembly (20) is configured such that the gas outlet (28) of the gas flow portion (40) is positioned to inject gas into the liquid flow portion (30) upstream of the liquid outlet (26), into the liquid flow portion (30) at the liquid outlet (26), or into an extension (35) of the liquid flow portion (30) downstream of the liquid outlet (26). Further, the injector assembly (20) is configured such that gas is injected into the liquid flow portion (30) or the extension thereof as a series of gas bubbles. The resulting microreactor assembly (100), and the injector assemblies utilized therein, which can be used with a variety of microreactor designs, effectively improves the interfacial surface area within the microstructure without requiring excessive reduction of microchannel dimensions.
    • 提供了包括流体微结构(10)和喷射器组件(20)的微反应器组件(100)。 喷射器组件(20)包括液体入口(22),气体入口(24),液体出口(26),气体出口(28),从液体入口(22)延伸的液体流动部分(30) 到液体出口(26)和从气体入口(24)延伸到气体出口(28)的气体流动部分(40)。 此外,喷射器组件(20)限定与流体微结构(10)的微通道输入端口(14)的注入界面。 喷射器组件(20)构造成使得气体流动部分(40)的气体出口(28)定位成将气体喷射到液体出口(26)上游的液体流动部分(30)中,进入液体流 在液体出口(26)处的部分(30),或液体出口(26)下游的液体流动部分(30)的延伸部(35)中。 此外,喷射器组件(20)构造成使得气体作为一系列气泡被喷射到液体流动部分(30)或其延伸部分中。 可以与各种微反应器设计一起使用的所得微反应器组件(100)和其中使用的喷射器组件有效地改善了微结构内的界面表面积,而不需要过度减小微通道尺寸。
    • 5. 发明申请
    • SYSTEMS AND METHODS FOR SCALE-UP OF CONTINUOUS FLOW REACTORS
    • 连续流动反应器定标系统及方法
    • WO2012173848A1
    • 2012-12-20
    • PCT/US2012/041192
    • 2012-06-07
    • CORNING INCORPORATEDGUIDAT, RolandLOBET, OlivierWOEHL, Pierre
    • GUIDAT, RolandLOBET, OlivierWOEHL, Pierre
    • B01J19/00
    • B01J19/0053B01J19/0093B01J2219/00015B01J2219/00824B01J2219/00831B01J2219/0086B01J2219/00873B01J2219/00995Y10T29/49
    • A method is disclosed for the seamless scale-up of a micro reactor process, to transfer lab test to a pilot or production unit, the process comprising the steps of using a wall material for the lab reactor with a thermal conductivity lower than 3 W/m-K, and using a wall material for the production reactor with a thermal conductivity higher than 5 W/m-K. According to one preferred embodiment, the velocity is kept constant, and the height of the channel is determined, in order to keep the volumetric heat transfer properties constant, according to the formula: wherein H G is the overall volumetric heat transfer coefficient in the pilot or production process; A B and C are constants; D h is the hydraulic diameter of the channel in the pilot or production process; λ w is the thermal conductivity of the wall in the pilot or production process; b is the empirically determined power to which the Reynolds number is raised in the equation for the Nusselt criteria (Nu = a-Re b Pr c ) for the type of flow in the pilot or production process; h is the height of the channel in the pilot or production process; and H G0 is the overall volumetric heat transfer coefficient in the lab-scale process.
    • 公开了一种用于微反应器过程的无缝放大以将实验室测试转移到先导或生产单元的方法,该方法包括以下步骤:使用导热率低于3W / mK,并且使用导热率高于5W / mK的生产反应器的壁材料。 根据一个优选实施例,速度保持恒定,并且确定通道的高度,以便保持体积传热性能恒定,其中HG是飞行员中的总体积传热系数,或 生产过程; A B和C是常数; Dh是先导或生产过程中通道的液压直径; ?w是先导或生产过程中壁的导热系数; b是在试点或生产过程中的流量类型的努塞尔标准(Nu = a-RebPrc)的方程中提高雷诺数的经验确定的功率; h是飞行员或生产过程中通道的高度; HG0是实验室规模过程中的总体积传热系数。