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1. 发明申请

WO2005101045A1 MAGNETIC RESONANCE IMAGING OF A MEDICAL DEVICE AND PROXIMATE BODY TISSUE 审中-公开
标题翻译：医疗装置的磁共振成像和放射性组织
公开(公告)号：WO2005101045A1
公开(公告)日：2005-10-27
申请号：PCT/US2005/012678
申请日：2005-04-14
申请人： BOSTON SCIENTIFIC SCIMED, INC. , ZHONG, Sheng-Ping , HELMUS, Michael N. , SMITH, Scott R. , HAMMER, Bruce E.
发明人： ZHONG, Sheng-Ping , HELMUS, Michael N. , SMITH, Scott R. , HAMMER, Bruce E.
IPC分类号： G01R33/28
CPC分类号： G01R33/285
摘要： Medical devices incorporate therein imaging materials having selected MRI detectable nuclei to provide useful magnetic resonance images of the medical devices and proximate body tissue. Also, a method generates MRI images of such a medical device, and involves performing first and second MRI processes on a body portion including at least a portion of the medical device to obtain, respectively, first and second image data. The first MRI process is adapted to detect MRI detectable nuclei present in the proximate body tissue, and the second MRI process is adapted to detect the selected MRI detectable nuclei contained in the device's imaging material. The selected MRI detectable nuclei incorporated in the imaging material is not the same nuclei that the first MRI process is adapted to detect. The second image data are combined with the first image data to produce image data for the medical device and the proximate body tissue.
摘要翻译：医疗装置包括具有选定的MRI可检测核的成像材料，以提供医疗装置和邻近身体组织的有用的磁共振图像。此外，一种方法产生这种医疗装置的MRI图像，并且涉及在包括医疗装置的至少一部分的主体部分上执行第一和第二MRI处理，以分别获得第一和第二图像数据。第一MRI过程适于检测存在于邻近身体组织中的MRI可检测核，并且第二MRI过程适于检测包含在装置的成像材料中的所选择的MRI可检测核。在成像材料中并入的所选择的MRI检测核并不是第一个MRI过程适用于检测的核。第二图像数据与第一图像数据组合以产生用于医疗装置和邻近身体组织的图像数据。

2. 发明申请

WO2006045074A2 LEADLESS CARDIAC STIMULATION SYSTEMS 审中-公开
标题翻译：无铅心脏刺激系统
公开(公告)号：WO2006045074A2
公开(公告)日：2006-04-27
申请号：PCT/US2005/037978
申请日：2005-10-19
申请人： BOSTON SCIENTIFIC SCIMED, INC. , HASTINGS, Roger N. , DRASSLER, William J. , LAFONTAINE, Daniel M. , SADASIVA, Anupama , SMITH, Scott R.
发明人： HASTINGS, Roger N. , DRASSLER, William J. , LAFONTAINE, Daniel M. , SADASIVA, Anupama , SMITH, Scott R.
IPC分类号： A61N1/05 , A61N1/378 , A61N1/372 , A61M31/00
CPC分类号： A61N1/3756 , A61N1/0587 , A61N1/059 , A61N1/08 , A61N1/3627 , A61N1/365 , A61N1/37205 , A61N1/37217 , A61N1/37223 , A61N1/37229 , A61N1/37241 , A61N1/37288 , A61N1/375 , A61N1/3787
摘要： Various configurations of systems that employ leadless electrodes to provide pacing therapy are provided. In one example, a system that provides multiple sites for pacing of myocardium of a heart includes wireless pacing electrodes that are implantable at sites proximate the myocardium using a percutaneous, transluminal, catheter delivery system. Each of the electrodes contains a source of electrical energy for pacing the myocardium and is adapted to receive electromagnetic energy from a source outside the myocardium. The system also includes a source adapted for placement outside the myocardium and that uses locally measured electrocardiograms to synchronize pacing of the heart by sending electromagnetic commands to the electrodes to pace the myocardium surrounding the electrodes. Also disclosed is various configurations of such systems, wireless electrode assemblies, and delivery catheters for delivering and implanting the electrode assemblies.
摘要翻译：提供了使用无引线电极来提供起搏治疗的各种构造的系统。在一个示例中，提供用于心脏心肌的多个部位的系统包括使用经皮，经腔，导管递送系统可植入位于心肌附近的位置的无线起搏电极。每个电极包含用于起搏心肌的电能源，并且适于从心肌外部的源接收电磁能。该系统还包括适于放置在心肌外部的源，并且使用局部测量的心电图来通过向电极发送电磁命令来同步心脏的起搏，以对电极周围的心肌进行加速。还公开了用于递送和植入电极组件的这种系统，无线电极组件和输送导管的各种配置。

3. 发明申请

WO2007067253A1 CARDIAC STIMULATION SYSTEM 审中-公开
标题翻译：心脏刺激系统
公开(公告)号：WO2007067253A1
公开(公告)日：2007-06-14
申请号：PCT/US2006/040291
申请日：2006-10-13
申请人： BOSTON SCIENTIFIC SCIMED, INC. , DRASLER, William J. , PIKUS, Michael J. , HASTINGS, Roger N. , SMITH, Scott R. , WILLARD, Martin R. , LAFONTAINE, Daniel M. , SAHOLT, Douglas R. , KVEEN, Graig L.
发明人： DRASLER, William J. , PIKUS, Michael J. , HASTINGS, Roger N. , SMITH, Scott R. , WILLARD, Martin R. , LAFONTAINE, Daniel M. , SAHOLT, Douglas R. , KVEEN, Graig L.
IPC分类号： A61N1/00 , A61B5/00
CPC分类号： A61N1/059 , A61B5/0031 , A61B5/042 , A61B5/6848 , A61B5/6882 , A61N1/0573 , A61N1/3684 , A61N1/37205 , A61N1/3756
摘要： Some embodiments of pacing systems employ wireless electrode assemblies to provide pacing therapy. The wireless electrode assemblies may wirelessly receive energy via an inductive coupling so as to provide electrical stimulation to the surrounding heart tissue. In certain embodiments, the wireless electrode assembly may include one or more biased tines that shift from a first position to a second position to secure the wireless electrode assembly into the inner wall of the heart chamber.
摘要翻译：起搏系统的一些实施例采用无线电极组件来提供起搏治疗。无线电极组件可以通过电感耦合无线地接收能量，以便向周围的心脏组织提供电刺激。在某些实施例中，无线电极组件可以包括从第一位置移动到第二位置的一个或多个偏置尖齿，以将无线电极组件固定到心室的内壁。

4. 发明申请

WO2012158186A1 PERCUTANEOUS MITRAL ANNULUS MINI-PLICATION 审中-公开
标题翻译：胰岛素敏感性微创
公开(公告)号：WO2012158186A1
公开(公告)日：2012-11-22
申请号：PCT/US2011/052805
申请日：2011-09-22
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： SMITH, Scott R. , JENSON, Mark L.
IPC分类号： A61B17/00 , A61B17/122 , A61B17/128 , A61B17/064
CPC分类号： A61B17/00234 , A61B17/0644 , A61B17/1227 , A61B17/1285 , A61B2017/00243 , A61B2017/081 , A61F2/2442
摘要： A plication clip comprises a first end portion; a second end portion; and a central portion connecting the first end portion to the second end portion. The first end portion is curved toward the second end portion, and the second end portion is curved toward the first end portion. The central portion has a curvilinear profile such that when the clip is deployed, a shorter length between the first end portion and the second end portion is formed. A delivery catheter and methods for deploying the plication clip are also provided.
摘要翻译：折叠夹包括第一端部; 第二端部; 以及将第一端部连接到第二端部的中心部。第一端部朝向第二端部弯曲，第二端部朝向第一端部弯曲。中心部分具有曲线轮廓，使得当夹子展开时，在第一端部和第二端部之间形成较短的长度。还提供了输送导管和用于展开折叠夹的方法。

5. 发明申请

WO2013101485A1 DEVICE AND METHODS FOR RENAL NERVE MODULATION MONITORING 审中-公开
标题翻译：用于神经调制监测的装置和方法
公开(公告)号：WO2013101485A1
公开(公告)日：2013-07-04
申请号：PCT/US2012/069475
申请日：2012-12-13
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： SMITH, Scott R.
IPC分类号： A61B18/14
CPC分类号： A61B18/14 , A61B18/1206 , A61B18/1492 , A61B18/16 , A61B18/24 , A61B2018/00029 , A61B2018/00267 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00642 , A61B2018/00702 , A61B2018/00761 , A61B2018/00875 , A61B2018/128 , A61B2018/1467 , A61B2018/1861 , A61B2218/002 , A61N7/022
摘要： Systems and methods for monitoring and performing tissue modulation are disclosed. An example system may include an elongate shaft having a distal end region and a proximal end and having at least two nerve modulation elements disposed adjacent to the distal end region. The nerve modulation elements may be used to determine and monitor changes in tissue adjacent to the modulation element and to effect tissue changes.
摘要翻译：公开了用于监测和执行组织调制的系统和方法。示例性系统可以包括具有远端区域和近端的细长轴，并且具有邻近远端区域设置的至少两个神经调制元件。神经调制元件可用于确定和监测与调制元件相邻的组织中的变化并影响组织变化。

6. 发明申请

WO2013074813A1 DEVICE AND METHODS FOR RENAL NERVE MODULATION MONITORING 审中-公开
标题翻译：用于神经调制监测的装置和方法
公开(公告)号：WO2013074813A1
公开(公告)日：2013-05-23
申请号：PCT/US2012/065318
申请日：2012-11-15
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： RICHARDSON, Leonard B. , SMITH, Scott R. , JENSON, Mark L.
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B17/320068 , A61B18/16 , A61B18/1815 , A61B18/20 , A61B90/00 , A61B90/39 , A61B2018/00029 , A61B2018/00285 , A61B2018/00434 , A61B2018/00446 , A61B2018/00511 , A61B2018/00547 , A61B2018/00577 , A61B2018/00815 , A61B2018/00821 , A61B2018/00875 , A61B2018/167 , F04C2270/0421
摘要： Systems and methods for monitoring and performing tissue modulation are disclosed. An example system may include an elongate shaft having a distal end region and a proximal end and having at least one modulation element and one sensing electrode disposed adjacent to the distal end region. The sensing electrode may be used to determine and monitor changes in tissue adjacent to the modulation element.
摘要翻译：公开了用于监测和执行组织调制的系统和方法。示例性系统可以包括具有远端区域和近端的细长轴，并且具有邻近远端区域设置的至少一个调制元件和一个感测电极。感测电极可用于确定和监测与调制元件相邻的组织中的变化。

7. 发明申请

WO2013074661A2 INTEGRATED ULTRASOUND ABLATION AND IMAGING DEVICE AND RELATED METHODS 审中-公开
标题翻译：一体化超声波吸收和成像装置及相关方法
公开(公告)号：WO2013074661A2
公开(公告)日：2013-05-23
申请号：PCT/US2012/065064
申请日：2012-11-14
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： HASTINGS, Roger N. , PIKUS, Michael J. , EDMUNDS, Kevin D. , SMITH, Scott R. , RICHARDSON, Leonard B. , TEO, Tat-Jin
IPC分类号： A61N7/00
CPC分类号： A61N7/00 , A61B8/12 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00636 , A61B2090/3784 , A61N7/022 , A61N2007/003 , A61N2007/0052 , A61N2007/0078 , A61N2007/0091 , A61N2007/0095 , A61N2007/027
摘要： Intravascular nerve modulation systems and methods for making and using the same are disclosed. An example system may include an elongate shaft having a proximal end region and a distal end region and a central longitudinal axis. An ablation transducer may be disposed at the distal end region. The system may also include a rotational drive configured to rotate the ablation transducer about the central longitudinal axis. A control and power system may be operably connected to the ablation transducer and the rotational drive. In some instances, the ablation transducer may be a combined ablation and imaging transducer.
摘要翻译：公开了血管内神经调节系统及其制造和使用方法。示例性系统可以包括具有近端区域和远端区域以及中心纵向轴线的细长轴。消融换能器可以设置在远端区域。该系统还可以包括旋转驱动器，其构造成围绕中心纵向轴线旋转消融换能器。控制和动力系统可以可操作地连接到消融换能器和旋转驱动器。在一些情况下，消融换能器可以是组合消融和成像换能器。

8. 发明申请

WO2013074218A1 SHAFT WITH ULTRASOUND TRANSDUCERS FOR NERVE MODULATION 审中-公开
标题翻译：用超声波传感器进行神经调制
公开(公告)号：WO2013074218A1
公开(公告)日：2013-05-23
申请号：PCT/US2012/059360
申请日：2012-10-09
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： SMITH, Scott R.
IPC分类号： A61N7/02 , A61N1/02
CPC分类号： A61N7/022 , A61B18/1815 , A61B18/20 , A61B2018/00636 , A61N2007/0078 , A61N2007/0091 , A61N2007/0095 , A61N2007/027
摘要： Systems for nerve modulation are disclosed. An example system (100) may include a first elongate element (102) having a distal end and a proximal end and having at least two nerve modulation elements (106a, 106b, 106c) disposed adjacent the distal end. The nerve modulation elements are ultrasound transducers. Activation of the nerve modulation elements may ablate multiple regions of a target area.
摘要翻译：公开了神经调制系统。示例性系统（100）可以包括具有远端和近端的具有邻近远端设置的至少两个神经调制元件（106a，106b，106c）的第一细长元件（102）。神经调制元件是超声换能器。神经调节元件的激活可以消融目标区域的多个区域。

9. 发明申请

WO2013055815A1 OFF -WALL ELECTRODE DEVICE FOR NERVE MODULATION 审中-公开
标题翻译：关闭用于神经调制的电极装置
公开(公告)号：WO2013055815A1
公开(公告)日：2013-04-18
申请号：PCT/US2012/059590
申请日：2012-10-10
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： SMITH, Scott R.
IPC分类号： A61B18/14 , A61N1/00
CPC分类号： A61B18/1492 , A61B2017/32096 , A61B2018/00107 , A61B2018/00267 , A61B2018/00279 , A61N1/0558
摘要： Systems for nerve modulation through the wall of a blood vessel are disclosed. An example system for nerve modulation may include an elongate member extending along a central elongate axis and having a proximal end and a distal end. The elongate member may have a radially expandable member disposed proximate the distal end. A tubular sheath may be cooperatively engaged with the expandable member such that the expandable member is collapsed when in the sheath and can expand when moved distally relative to and past a distal end of the sheath. The expandable member may include a plurality of electrodes and a plurality of spacer struts. Each spacer strut may be configured such that when the self-expanding member is in an expanded state the spacer strut extends out radially further than the electrodes from the central elongate axis.
摘要翻译：公开了通过血管壁进行神经调节的系统。用于神经调节的示例性系统可以包括沿着中心细长轴线延伸并具有近端和远端的细长构件。细长构件可以具有靠近远端设置的径向可扩张构件。管状护套可以与可膨胀构件协作地接合，使得可伸缩构件在护套中时折叠，并且当相对于护套远端移动并远离护套的远端时可膨胀。可膨胀构件可以包括多个电极和多个间隔支柱。每个间隔支柱可以被配置成使得当自膨胀构件处于膨胀状态时，间隔支柱从中心细长轴线沿径向延伸远离电极。

10. 发明申请

WO2013055537A1 ABLATION CATHETER WITH INSULATED TIP 审中-公开
标题翻译：绝缘导线带绝缘提示
公开(公告)号：WO2013055537A1
公开(公告)日：2013-04-18
申请号：PCT/US2012/058078
申请日：2012-09-28
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： SMITH, Scott R.
IPC分类号： A61B18/14 , A61M25/00 , A61B18/00 , A61N1/05 , A61N1/40
CPC分类号： A61B18/1492 , A61B2018/00083 , A61B2018/00095 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61N1/056 , A61N1/40
摘要： An ablation catheter configured to be navigated through a vessel to ablate tissue, the ablation catheter comprising an elongate catheter shaft having a proximal end and a distal end. An electrode is positioned near the distal end of the elongate shaft, and is configured to transmit radio-frequency energy into a vessel wall. An electrically insulative tip at the distal end of the catheter keeps the electrode away from the blood vessel wall
摘要翻译：消融导管，被配置为通过容器导航以烧蚀组织，所述消融导管包括具有近端和远端的细长导管轴。电极位于细长轴的远端附近，并且被配置为将射频能量传输到血管壁。在导管的远端处的电绝缘尖端保持电极远离血管壁

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