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1. 发明申请

WO2005086661A3 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE IN TREATING METABOLIC DISORDERS 审中-公开
标题翻译：化合物，药物组合物和用于治疗代谢障碍的方法
公开(公告)号：WO2005086661A3
公开(公告)日：2006-05-04
申请号：PCT/US2005005815
申请日：2005-02-24
申请人： AMGEN INC , AKERMAN MICHELLE , HOUZE JONATHAN , LIN DANIEL C H , LIU JIWEN , LUO JIAN , MEDINA JULIO C , QIU WEI , REAGAN JEFFREY D , SCHMITT MICHAEL J , WANG YINGCAI , SHARMA RAJIV , SHUTTLEWORTH STEPHEN J , SUN YING , ZHANG JIAN , ZHU LIUSHENG
发明人： AKERMAN MICHELLE , HOUZE JONATHAN , LIN DANIEL C H , LIU JIWEN , LUO JIAN , MEDINA JULIO C , QIU WEI , REAGAN JEFFREY D , SCHMITT MICHAEL J , WANG YINGCAI , SHARMA RAJIV , SHUTTLEWORTH STEPHEN J , SUN YING , ZHANG JIAN , ZHU LIUSHENG
IPC分类号： C07D277/24 , C07D277/30 , C07C53/132 , A61K31/19 , A61K31/215 , A61K31/42 , C07C213/00 , C07C277/00
CPC分类号： C07D277/24 , C07D277/30
摘要： The present invention provides compounds useful, for example, for modulating insulin levels in a subject and that have the general formula Q-L 1 -P-L 2 -M-X-L 3 -A wherein the definitions of the variables Q, L 1 , P, L 2 , M, X, L 3 and A are provided herein. The present invention also provides compositions and methods for use of the compounds, for instance, for treatment of type II diabetes.
摘要翻译：本发明提供了可用于例如用于调节受试者中胰岛素水平的化合物，其具有通式QL 1 -PL 2 -MXL 3 / SUP> -A，其中变量Q，L 1，P，L 2，M，X，L 3和A的定义是本文提供。本发明还提供了用于化合物的组合物和方法，例如用于治疗II型糖尿病。

2. 发明申请

WO2008002591A2 METHODS FOR TREATING ATHEROSCLEROSIS 审中-公开
标题翻译：治疗动脉粥样硬化的方法
公开(公告)号：WO2008002591A2
公开(公告)日：2008-01-03
申请号：PCT/US2007014873
申请日：2007-06-26
申请人： AMGEN INC , KAYSER FRANK , LABELLE MARC , SHAN BEI , ZHANG JIAN , ZHOU MINGYUE
发明人： KAYSER FRANK , LABELLE MARC , SHAN BEI , ZHANG JIAN , ZHOU MINGYUE
CPC分类号： C12N9/1029 , A61K31/497 , A61K38/45 , C07D403/12 , C07D417/12
摘要： The invention provides compounds, pharmaceutical compositions and methods for treating atherosclerosis, inflammation, thrombosis and other conditions and for decreasing or prevention of accumulation of cholesterol in a subject by modifying LCAT polypeptide.
摘要翻译：本发明提供了通过修饰LCAT多肽来治疗动脉粥样硬化，炎症，血栓形成和其他病症并降低或预防受试者中胆固醇积聚的化合物，药物组合物和方法。

3. 发明申请

WO2008048207A3 ELECTRICALLY CONDUCTIVE ADHESIVES 审中-公开
标题翻译：电导电胶
公开(公告)号：WO2008048207A3
公开(公告)日：2008-12-18
申请号：PCT/US2006025526
申请日：2006-06-28
申请人： GEN ELECTRIC , SIMONE DAVIDE LOUIS , ANGELIU THOMAS MARTIN , TONAPI SANDEEP SHRIKANT , GIBSON III DAVID ALEXANDER , ZHANG JIAN
发明人： SIMONE DAVIDE LOUIS , ANGELIU THOMAS MARTIN , TONAPI SANDEEP SHRIKANT , GIBSON III DAVID ALEXANDER , ZHANG JIAN
IPC分类号： C09J9/02 , C09J11/04 , C09J121/00 , H01B1/22
CPC分类号： H01B1/22 , B82Y30/00 , C08K3/08 , C08K2201/011 , C08L83/00 , C08L2666/54 , C09J9/02 , C09J11/04 , C09J183/04 , C09J2483/00 , H05K3/321 , H05K2201/0133 , H05K2201/0257 , H05K2201/0266 , H05K2201/0272
摘要： The present invention provides an electrically conductive adhesive composition having cured low modulus elastomer and metallurgically-bonded micron-sized metal particles and nano-sized metal particles. The low modulus elastomer provides the mechanical robustness and reliability by relieving the stresses generated; and the metallurgically-bonded micron-sized metal particles and nano-sized metal particles provide a continuous conducting path with minimized interface resistance. Addition of nano-sized metal particles lowers the fusion temperature and allows the metallurgical-bonding to occur at manageable temperatures.
摘要翻译：本发明提供一种导电粘合剂组合物，其具有固化的低模量弹性体和冶金结合的微米级金属颗粒和纳米尺寸的金属颗粒。低弹性弹性体通过减轻产生的应力来提供机械坚固性和可靠性; 并且冶金结合的微米级金属颗粒和纳米级金属颗粒提供具有最小界面电阻的连续导电路径。纳米尺寸金属颗粒的添加降低了熔化温度，并允许在可控温度下进行冶金结合。

4. 发明申请

WO2007101029A3 LONGITUDINALLY PUMPED SOLID STATE LASER AND METHODS OF MAKING AND USING 审中-公开
标题翻译：长期泵送固态激光器及其制造和使用方法
公开(公告)号：WO2007101029A3
公开(公告)日：2008-04-10
申请号：PCT/US2007062469
申请日：2007-02-21
申请人： QUANTRONIX CORP , ZHANG JIAN , SONG JIE , GUO BO , LIU KUO-CHING
发明人： ZHANG JIAN , SONG JIE , GUO BO , LIU KUO-CHING
IPC分类号： H01S3/081
CPC分类号： H01S3/09415 , H01S3/025 , H01S3/0405 , H01S3/042 , H01S3/0606 , H01S3/0612 , H01S3/081 , H01S3/0815 , H01S3/117 , H01S3/235
摘要： A laser apparatus for producing a laser light beam can include a gain medium; a pump light source to provide a pump light beam to the gain medium; a first reflector disposed between the first gain medium and the first pump light source and spaced apart from a gain portion of the first gain medium; a second reflector; and an output coupler. The first reflector is substantially reflective to the laser light beam and substantially transmissive to the pump light beam. The first and second reflectors and the output coupler define a folded beam path having a first portion and a second portion. The first portion of the beam path extends from the first reflector to the second reflector through the gain medium and the second portion of the beam path extends from the first reflector to the output coupler through the gain medium. The first and second beam paths define, within the gain medium, a non-zero folding angle. Optionally, the laser apparatus can include a second pump light source that can pump the same, or a second, gain medium.
摘要翻译：用于产生激光束的激光装置可以包括增益介质; 泵浦光源，用于向增益介质提供泵浦光束; 布置在第一增益介质和第一泵浦光源之间并与第一增益介质的增益部分间隔开的第一反射器; 第二反射器; 和输出耦合器。第一反射器基本上反射激光束并基本上对泵浦光束透射。第一和第二反射器和输出耦合器限定具有第一部分和第二部分的折叠光束路径。光束路径的第一部分通过增益介质从第一反射器延伸到第二反射器，并且光束路径的第二部分通过增益介质从第一反射器延伸到输出耦合器。第一和第二光束路径在增益介质内限定非零折叠角度。可选地，激光装置可以包括可以泵浦相同或第二增益介质的第二泵浦光源。

5. 发明申请

WO03054144A8 HUMAN RAS INTERACTING PROTEIN 审中-公开
标题翻译：人类RAS相互作用的蛋白质
公开(公告)号：WO03054144A8
公开(公告)日：2007-07-19
申请号：PCT/US0235128
申请日：2002-11-01
申请人： AMERSHAM PLC , ZHANG JIAN
发明人： ZHANG JIAN
IPC分类号： C07H21/04 , A01K67/00 , A61K38/00 , A61K39/395 , A61K48/00 , C07K14/00 , C07K14/47 , C07K16/00 , C12N15/12 , C12Q1/68
CPC分类号： C07K14/4702 , A01K2217/05 , A01K2217/075 , A61K38/00 , A61K48/00 , A61K2039/505 , C07K2319/00
摘要： The invention provides isolated nucleic acids that encode a human Ras interacting protein (RasIn), including a shorter isoform (RasInS), and fragments thereof, vectors for propagating and expressing RasIn nucleic acids, host cells comprising the nucleic acids and vectors of the present invention, proteins, protein fragments, and protein fusions of the novel RasIn isoforms, and antibodies thereto. The invention further provides transgenic cells and non-human organisms comprising human RasIn nucleic acids, and transgenic cells and non-human organisms with targeted disruption of the endogenous orthologue of the human RasIn gene. The invention further provides pharmaceutical formulations of the nucleic acids, proteins, and antibodies of the present invention, and diagnostic, investigational, and therapeutic methods based on the RasIn nucleic acids, proteins, and antibodies of the present invention.
摘要翻译：本发明提供编码人类Ras相互作用蛋白（RasIn）的分离的核酸，包括较短的同种型（RasInS）及其片段，用于增殖和表达RasIn核酸的载体，包含本发明的核酸和载体的宿主细胞，蛋白质，蛋白质片段和新型RasIn同种型的蛋白质融合体及其抗体。本发明进一步提供包含人RasIn核酸的转基因细胞和非人生物，以及靶向破坏人RasIn基因的内源直向同源物的转基因细胞和非人生物。本发明还提供本发明的核酸，蛋白质和抗体的药物制剂，以及基于本发明的RasIn核酸，蛋白质和抗体的诊断，研究和治疗方法。

6. 发明申请

WO2012125939A3 METHOD AND SYSTEM FOR EFFICIENTLY PROCESSING LARGE VOLUMES OF COMPLEX SMALL VALUE FINANCIAL TRANSACTIONS 审中-公开
标题翻译：用于有效处理大量复杂小额金融交易的方法和系统
公开(公告)号：WO2012125939A3
公开(公告)日：2012-12-27
申请号：PCT/US2012029473
申请日：2012-03-16
申请人： GRIDX INC , ZHANG JIAN
发明人： ZHANG JIAN
IPC分类号： G06Q30/06
CPC分类号： G06Q40/00
摘要： The present invention provides a means for a system to model the financial terms of a contract. The system receives a contract and the details of a transaction governed by the contract as inputs and outputs a processed transaction. The system models the financial terms of the contract as a function of one or more parameters. Each of the parameters are further reduced to one or more rules, where each rule represents the terms of the contract as a set of conditions and associated actions. The actions are performed by the system when a corresponding condition is satisfied. The system determines the values of the various parameters by analyzing the outcome of the condition-action sets in relation to the given input transaction.
摘要翻译：本发明提供了一种用于系统对合同的财务条款建模的手段。系统收到一份合同，并将合同规定的交易细节作为输入并输出处理后的交易。系统将合同的财务条款建模为一个或多个参数的函数。每个参数都进一步缩减为一个或多个规则，其中每个规则将合同条款表示为一组条件和相关操作。系统在满足相应条件时执行这些操作。系统通过分析与给定输入事务相关的条件动作集的结果来确定各种参数的值。

7. 发明申请

WO2007052214A3 CONTENT MANAGEMENT DEVICE AND METHOD 审中-公开
标题翻译：内容管理设备和方法
公开(公告)号：WO2007052214A3
公开(公告)日：2007-08-16
申请号：PCT/IB2006054021
申请日：2006-10-31
申请人： KONINKL PHILIPS ELECTRONICS NV , WANG GANG , ZENG YONGQIN , CHEN XIN , ZHANG JIAN , KRAVTSOVA NATASHA , GASSEL JOZEF PIETER , LUITJENS STEVEN BROEILS , DECLAN KELLY PATRICK , TU JIAWEN
发明人： WANG GANG , ZENG YONGQIN , CHEN XIN , ZHANG JIAN , KRAVTSOVA NATASHA , GASSEL JOZEF PIETER , LUITJENS STEVEN BROEILS , DECLAN KELLY PATRICK , TU JIAWEN
IPC分类号： G06F17/30
CPC分类号： G06F17/3087
摘要： The present invention provides a content management device and method. The content management device comprises a context-aware information-generating device, for obtaining context-aware information related to the content according to a position where the content is created and site-related information related to the position; and an association device, for associating the context-aware information with the content. By utilizing the present invention, context-aware information related to the content can be generated according to a position where the content is created and site-related information related to the position. The content management device and method has an Ambient Intelligent (AmI) feature and can be used to create personalized metadata for users conveniently and intelligently.
摘要翻译：本发明提供一种内容管理装置和方法。内容管理装置包括上下文感知信息生成装置，用于根据创建内容的位置和与该位置相关的站点相关信息来获取与内容相关的上下文感知信息; 以及用于将上下文感知信息与内容相关联的关联设备。通过利用本发明，可以根据创建内容的位置和与该位置相关的站点相关信息来生成与内容相关的上下文感知信息。内容管理装置和方法具有环境智能（AmI）功能，可以方便，智能地为用户创建个性化元数据。

8. 发明申请

WO2005123549A3 SERIAL THERMAL PROCESSOR ARRANGEMENT 审中-公开
标题翻译：串行热处理装置
公开(公告)号：WO2005123549A3
公开(公告)日：2007-08-09
申请号：PCT/US2005020263
申请日：2005-06-09
申请人： SEMIGEAR INC , ZHANG JIAN
发明人： ZHANG JIAN
IPC分类号： H01L21/44 , B65G1/133 , H01L21/00 , H01L21/60
CPC分类号： H01L21/67109 , H01L21/67161 , H01L21/67748 , H01L24/11 , H01L2224/13099 , H01L2924/01006 , H01L2924/01029 , H01L2924/01047 , H01L2924/01074 , H01L2924/01075 , H01L2924/01078 , H01L2924/01082 , H01L2924/01322 , H01L2924/014 , Y10S438/907 , Y10S438/908
摘要： A serial thermal processing arrangement for treating a wafer of semiconductor material, by performing plural formic acid treatment steps on the wafer. The wafer is load into a chamber at an initial station at atmospheric pressure and the chamber is purged with nitrogen gas; formic acid vapor and nitrogen are introduced at a first (1) and second (2) subsequent stations, where the wafer is heated at ambient atmospheric pressure; the wafer is rotated to a third subsequent station (3) under vacuum and heated in the absence of chemical treatment; the wafer is rotated to a fourth subsequent station (4), formic acid vapor and nitrogen are introduced and the wafer is heated at ambient atmospheric pressure; the wafer is rotated to a fifth subsequent station (5), nitrogen gas is introduced, and the wafer is cooled at ambient atmospheric pressure; and the wafer is rotated to a sixth subsequent station (6) for unloading the wafer from its chamber.
摘要翻译：一种通过在晶片上进行多个甲酸处理步骤来处理半导体材料晶片的串联热处理装置。在大气压下将晶片装载到初始站的室中，并用氮气吹扫室; 在第一（1）和第二（2）个后续站引入甲酸蒸气和氮气，其中晶片在环境大气压下加热; 将晶片在真空下旋转到第三后续工位（3），并在没有化学处理的情况下加热; 将晶片旋转到第四后续工位（4），引入甲酸蒸气和氮气，并将晶片在环境大气压下加热; 将晶片旋转到第五个后续工位（5），引入氮气，并将晶片在环境大气压下冷却; 并且将晶片旋转到第六个后续工位（6），用于从其腔室卸载晶片。

9. 发明申请

WO2004052489A3 METHODS FOR ASSEMBLY AND SORTING OF NANOSTRUCTURE-CONTAINING MATERIALS AND RELATED ARTICLES 审中-公开
标题翻译：包含纳米结构材料和相关文章的组装和分选方法
公开(公告)号：WO2004052489A3
公开(公告)日：2004-10-07
申请号：PCT/US0338743
申请日：2003-12-08
申请人： UNIV NORTH CAROLINA , ZHOU OTTO Z , TANG JIE , GENG HUAIZHI , QIN LU-CHANG , ZHANG JIAN , YANG GUANG
发明人： ZHOU OTTO Z , TANG JIE , GENG HUAIZHI , QIN LU-CHANG , ZHANG JIAN , YANG GUANG
IPC分类号： B01D20060101 , B01D1/00 , B01D57/02 , B05D1/12 , B05D3/14 , B82B3/00 , C25D13/00 , G01L1/20 , G01Q30/02 , G01Q60/00 , G01Q70/12 , G01Q70/16 , H01J9/02 , H01R43/00 , H05K1/16
CPC分类号： G01Q70/16 , C25D13/00 , G01Q70/12 , H01J9/025 , H01J2201/30469 , Y10S977/84 , Y10S977/845 , Y10T29/4913 , Y10T29/49169
摘要： A method for depositing a nanostructure-containing material onto an object or substrate includes one or more of the following: forming a solution or suspension of nanostructure-containing material (420); selectively adding "chargers" to the solution (420); immersing electrodes (410, 430) in the solution (420), the substrate or object upon which the nanostructure material is to be deposited acting as one of the electrodes (430); applying a direct and/or alternating current electrical field between the two electrodes (410, 430) for a certain period of time, thereby causing the nanostructure materials in the solution (420) to migrate toward and attach themselves to the substrate electrode (450); and subsequent optional processing of the coated substrate. Associated objects and devices are also provided. A method for separating nanostructures based on their properties and/or geometry is also described.
摘要翻译：一种将纳米结构材料沉积到物体或基底上的方法包括以下一种或多种：形成含纳米结构材料的溶液或悬浮液（420）; 选择性地将“充电器”添加到溶液（420）中; 将电极（410,430）浸入溶液（420）中，沉积纳米结构材料的基底或物体用作电极（430）之一; 在两个电极（410,430）之间施加直接和/或交流电场一段时间，从而使溶液（420）中的纳米结构材料迁移并将其附着到衬底电极（450）上， ; 并且随后可选地处理涂覆的基底。还提供了相关对象和设备。还描述了基于其性质和/或几何形状分离纳米结构的方法。

10. 发明申请

WO2004002216A2 NOVEL INDUCIBLE GENES FROM ALFALFA AND METHODS OF USE THEREOF 审中-公开
标题翻译：来自ALFALFA的新型可溶性基因及其使用方法
公开(公告)号：WO2004002216A2
公开(公告)日：2004-01-08
申请号：PCT/CA0300964
申请日：2003-06-27
申请人： UNIV GUELPH , ERICKSON LARRY , ZHANG JIAN
发明人： ERICKSON LARRY , ZHANG JIAN
IPC分类号： C07K14/415 , C12N15/82 , A01H5/00 , C12N5/14 , C12Q1/68
CPC分类号： C12N15/8237 , C07K14/415 , C12N15/8257
摘要： The present invention relates to novel inducible genes from alfalfa. These genes are highly induced following mechanical harvesting or wounding of alfalfa. The genes are useful for inducible production of heterologous proteins following harvesting.
摘要翻译：本发明涉及来自苜蓿的新型诱导型基因。这些基因在机械收获或苜蓿伤害后高度诱导。这些基因在收获后可用于诱导产生异源蛋白质。

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