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1. 发明申请

WO0218006A2 LEADS FOR PACING AND/OR SENSING THE HEART FROM WITHIN THE CORONARY VEINS 审中-公开
标题翻译：用于从冠状动脉内切开和/或感测心脏的领导
公开(公告)号：WO0218006A2
公开(公告)日：2002-03-07
申请号：PCT/US0127022
申请日：2001-08-30
申请人： CARDIAC PACEMAKERS INC , WESTLUND RANDY , TOCKMAN BRUCE , WARREN JAY A , SCHEINER AVRAM , HAIL RONALD W JR , KELLEY PETER T , REPASKY CHRISTINA , BYE LYLE A , SOLTIS BRIAN D
发明人： WESTLUND RANDY , TOCKMAN BRUCE , WARREN JAY A , SCHEINER AVRAM , HAIL RONALD W JR , KELLEY PETER T , REPASKY CHRISTINA , BYE LYLE A , SOLTIS BRIAN D
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead (100) for monitoring or simulating cardiac activity is provided. The lead (100) is adapted for implantation on or about the heart within the coronary vasculature and for connection to a signal generator (140). The lead is constructed and arranged so that when it is implanted, the electrodes (122) are housed in the coronary vasculature and urged into intimate contact a vessel wall (128). The lead optionally includes a tapered, flexible lead body portion that is distal to a biased portion.
摘要翻译：提供了用于监测或模拟心脏活动的导联（100）。引线（100）适于植入在冠状脉管系统内或心脏周围，并用于连接到信号发生器（140）。引线被构造和布置成使得当其被植入时，电极（122）容纳在冠状脉管系统中并被促使与血管壁（128）紧密接触。导线可选地包括在偏压部分的远侧的锥形的柔性引线主体部分。

2. 发明申请

WO2008100392A3 IMPLANTABLE MEDICAL DEVICE WITH FIXATION MECHANISM 审中-公开
标题翻译：具有固定机构的可植入医疗器械
公开(公告)号：WO2008100392A3
公开(公告)日：2009-04-16
申请号：PCT/US2008001512
申请日：2008-02-05
申请人： CARDIAC PACEMAKERS INC , LIBBUS IMAD , WESTLUND RANDY
发明人： LIBBUS IMAD , WESTLUND RANDY
IPC分类号： A61N1/36
CPC分类号： A61N1/0558 , A61N1/36114 , A61N1/372 , A61N1/37205 , A61N1/3756
摘要： Miniature implantable medical devices each include a fixation mechanism to prevent the device from migrating in the body of a patient after implantation. The fixation mechanism is activated after the device is positioned in the body. In one embodiment, the miniature implantable medical devices each include a circuit to deliver neurostimulation. In one embodiment, the fixation mechanism includes one or more externally activated anchoring devices each configured to switch from a substantially non-anchoring state to a substantially anchoring state in response to an externally applied energy. In another embodiment, implantable medical devices are magnetically attracted to each other to prevent the devices from migrating in the body after implantation.
摘要翻译：微型可植入医疗装置各自包括固定机构，以防止装置在植入后在患者体内迁移。在装置定位在体内后，固定机构被激活。在一个实施例中，微型可植入医疗装置各自包括用于递送神经刺激的电路。在一个实施例中，固定机构包括一个或多个外部激活的锚固装置，其各自被配置为响应于外部施加的能量而从基本上非锚定状态转换到基本锚定状态。在另一个实施例中，可植入医疗装置彼此磁吸引以防止装置在植入后在体内迁移。

3. 发明申请

WO2008100392A2 IMPLANTABLE MEDICAL DEVICE WITH FIXATION MECHANISM 审中-公开
标题翻译：具有固定机构的可植入医疗器械
公开(公告)号：WO2008100392A2
公开(公告)日：2008-08-21
申请号：PCT/US2008/001512
申请日：2008-02-05
申请人： CARDIAC PACEMAKERS, INC. , LIBBUS, Imad , WESTLUND, Randy
发明人： LIBBUS, Imad , WESTLUND, Randy
CPC分类号： A61N1/0558 , A61N1/36114 , A61N1/372 , A61N1/37205 , A61N1/3756
摘要： Miniature implantable medical devices each include a fixation mechanism to prevent the device from migrating in the body of a patient after implantation. The fixation mechanism is activated after the device is positioned in the body. In one embodiment, the miniature implantable medical devices each include a circuit to deliver neurostimulation. In one embodiment, the fixation mechanism includes one or more externally activated anchoring devices each configured to switch from a substantially non-anchoring state to a substantially anchoring state in response to an externally applied energy. In another embodiment, implantable medical devices are magnetically attracted to each other to prevent the devices from migrating in the body after implantation.
摘要翻译：微型可植入医疗装置各自包括固定机构，以防止装置在植入后在患者体内迁移。在装置定位在体内后，固定机构被激活。在一个实施例中，微型可植入医疗装置各自包括用于递送神经刺激的电路。在一个实施例中，固定机构包括一个或多个外部激活的锚固装置，其各自被配置为响应于外部施加的能量而从基本上非锚定状态切换到基本锚定状态。在另一个实施例中，可植入医疗装置彼此磁吸引以防止装置在植入后在体内迁移。

4. 发明申请

WO2008024718A1 EPICARDIAL LEAD 审中-公开
公开(公告)号：WO2008024718A1
公开(公告)日：2008-02-28
申请号：PCT/US2007/076323
申请日：2007-08-20
申请人： CARDIAC PACEMAKERS, INC. , CALLAS, Peter L. , GREENLAND, John S. , HEIL JR., Ronald W. , WESTLUND, Randy W. , KELLEY, Peter T.
发明人： CALLAS, Peter L. , GREENLAND, John S. , HEIL JR., Ronald W. , WESTLUND, Randy W. , KELLEY, Peter T.
IPC分类号： A61N1/05
CPC分类号： A61N1/059
摘要： A lead for implanting into the epicardium includes a pair of tissue anchors coupled to a tissue engaging member, forming an anchor mechanism. The tissue anchors include electrodes coupled to conductors extending from the tissue engaging member. The tissue anchors are movable from a low profile configuration to an implanting configuration in which the tissue anchors are angled away from the tissue engaging member. A device for implanting the lead includes one or more lumens, including a lead lumen and a vacuum lumen terminating at a distal opening in the device. Suction is applied at the distal opening through the vacuum lumen to draw an epicardial bleb. The anchor mechanism of the lead is withdrawn proximally past the bleb, causing the tissue anchors to pierce the epicardium. The device is then withdrawn proximally over the conductors.
摘要翻译：用于植入到心外膜的引线包括耦合到组织接合构件的一对组织锚，形成锚固机构。组织锚定器包括耦合到从组织接合构件延伸的导体的电极。组织锚固件可从低轮廓构型移动到植入构造，其中组织锚定件远离组织接合构件成角度。用于植入引线的装置包括一个或多个腔，包括引导腔和终止于装置中的远端开口处的真空腔。通过真空腔在远端开口处施加抽吸以绘制心外膜。铅的锚定机构在近端被撤回通过气泡，导致组织锚固件刺穿心外膜。然后将器件向近端退出导体。

5. 发明申请

WO2011066002A2 MEDICAL LEAD WITH PREFORMED BIAS 审中-公开
标题翻译：具有预先偏差的医学领域
公开(公告)号：WO2011066002A2
公开(公告)日：2011-06-03
申请号：PCT/US2010045993
申请日：2010-08-19
申请人： CARDIAC CONCEPTS INC , WESTLUND RANDY W , LYNN MARK C
发明人： WESTLUND RANDY W , LYNN MARK C
IPC分类号： A61N1/05
CPC分类号： A61N1/0558 , A61N1/056 , A61N1/057
摘要： A medical electrical lead and methods of implanting medical electrical leads in lumens. Leads in accordance with the invention employ preformed biases to stabilize the lead within a lumen and to orient electrodes in a preferred orientation.
摘要翻译：一种医用电导线，以及以流明植入医用电线的方法。根据本发明的引线采用预先形成的偏压，以使引线在管腔内稳定并且以优选取向定向电极。

6. 发明申请

WO2011031427A1 RESPIRATORY RECTIFICATION 审中-公开
标题翻译：呼吸恢复
公开(公告)号：WO2011031427A1
公开(公告)日：2011-03-17
申请号：PCT/US2010/045992
申请日：2010-08-19
申请人： CARDIAC CONCEPTS, INC. , GELFAND, Mark , LYNN, Mark, C. , WESTLUND, Randy, W. , JAMES, Kristofer, J. , PANTELEON, Antonis , GOBLISH, Todd, P.
发明人： GELFAND, Mark , LYNN, Mark, C. , WESTLUND, Randy, W. , JAMES, Kristofer, J. , PANTELEON, Antonis , GOBLISH, Todd, P.
IPC分类号： A61N1/36
CPC分类号： A61N1/3601 , A61N1/3611 , A61N1/36171
摘要： A means for treating breathing disorders by stimulating respiratory muscles or nerves to entrain respiratory systems while leaving respiratory drive intact. Embodiments of the invention employ frequency analysis to determine if appropriate stimulation energy is being applied.
摘要翻译：一种通过刺激呼吸肌或神经夹带呼吸系统同时使呼吸驱动完好无损来治疗呼吸障碍的手段。本发明的实施例采用频率分析来确定是否正在施加适当的刺激能量。

7. 发明申请

WO2008094349A1 SPIRAL CONFIGURATIONS FOR INTRAVASCULAR LEAD STABILITY 审中-公开
标题翻译：用于血管引导稳定性的螺旋配置
公开(公告)号：WO2008094349A1
公开(公告)日：2008-08-07
申请号：PCT/US2007/086127
申请日：2007-11-30
申请人： CARDIAC PACEMAKERS, INC. , BLY, Mark, J. , WESTLUND, Randy, W. , HEIL, Ronald, W., Jr. , KOOP, Brendan, E. , ZAREMBO, Paul, E.
发明人： BLY, Mark, J. , WESTLUND, Randy, W. , HEIL, Ronald, W., Jr. , KOOP, Brendan, E. , ZAREMBO, Paul, E.
IPC分类号： A61N1/05 , A61N1/36
CPC分类号： A61N1/057 , A61N1/0558 , A61N1/36114
摘要： A medical electrical lead for transvascularly stimulating a nerve, muscle or other tissue from an adjacent vessel is described. The lead includes an expandable distal portion having one or more spirals for securing and stabilizing the lead within the vessel.
摘要翻译：描述了用于从相邻容器中经血管刺激神经，肌肉或其他组织的医用电引线。引线包括具有一个或多个螺旋的可扩展远端部分，用于固定和稳定血管内的引线。

8. 发明申请

WO2008094346A1 METHOD AND APPARATUS FOR DELIVERING A TRANSVASCULAR LEAD 审中-公开
标题翻译：用于输送透明导线的方法和装置
公开(公告)号：WO2008094346A1
公开(公告)日：2008-08-07
申请号：PCT/US2007/086120
申请日：2007-11-30
申请人： CARDIAC PACEMAKERS, INC. , BLY, Mark, J. , WESTLUND, Randy, W.
发明人： BLY, Mark, J. , WESTLUND, Randy, W.
IPC分类号： A61N1/05 , A61N1/372
CPC分类号： A61N1/056 , A61N1/36114 , A61N1/372
摘要： A lead delivery system is described for delivering a medical electrical lead to an internal jugular vein (IJV) through a subclavian vein. The system includes an inner catheter having an inner catheter curve configured to direct the distal end of the catheter into to the IJV when positioned in the subclavian vein. The stiffness of the inner catheter decreases in an inner catheter transition region in a direction from the proximal end to the distal end. An outer catheter extends from a proximal end to a distal end and is sized to slide over the inner catheter. The outer catheter includes an outer catheter curve. The stiffness of the outer catheter decreases in an outer catheter transition region in a direction from the proximal end to the distal end.
摘要翻译：描述了用于通过锁骨下静脉将医用电导线递送到颈内静脉（IJV）的引导输送系统。所述系统包括内导管，所述内导管具有构造成当定位在锁骨下静脉中时将导管的远端引导至IJV。内导管的刚度在从近端到远端的方向上在内导管过渡区域中减小。外导管从近端延伸到远端，并且其尺寸设计成在内导管上滑动。外导管包括外导管曲线。外导管的刚度在从近端到远端的方向上在外导管过渡区域中减小。

9. 发明申请

WO2007053298A3 LEAD AND DELIVERY SYSTEM TO DETECT AND TREAT A MYOCARDIAL INFARCTION REGION 审中-公开
标题翻译：引导和交付系统来检测和治疗心肌梗塞区域
公开(公告)号：WO2007053298A3
公开(公告)日：2007-07-05
申请号：PCT/US2006040682
申请日：2006-10-13
申请人： CARDIAC PACEMAKERS INC , PASTORE JOSEPH M , SALO RODNEY W , HEIL JR RONALD W , WESTLUND RANDY
发明人： PASTORE JOSEPH M , SALO RODNEY W , HEIL JR RONALD W , WESTLUND RANDY
IPC分类号： A61N1/05
CPC分类号： A61N1/0587 , A61N1/059 , A61N1/3627
摘要： A method includes mounting an anchor member to a surface of a heart, the anchor member having a tension member coupled to the anchor member, advancing a lead body along the tension member, the lead body including a plurality of electrodes disposed along the lead body, identifying an MI region of the heart, positioning the plurality of electrodes at or near the MI region, affixing the tension member to the lead body to hold the electrodes in position, and delivering pulses through the plurality of electrodes to the heart.
摘要翻译：一种方法包括将锚定构件安装到心脏的表面，所述锚定构件具有联接到所述锚定构件的张紧构件，使所述引线体沿着所述张紧构件前进，所述引线主体包括沿着所述引线主体设置的多个电极，识别心脏的MI区域，将多个电极定位在MI区域处或附近，将张紧构件固定到引线体以将电极保持在适当位置，并将脉冲通过多个电极传递到心脏。

10. 发明申请

WO2007053298A2 LEAD AND DELIVERY SYSTEM TO DETECT AND TREAT A MYOCARDIAL INFARCTION REGION 审中-公开
标题翻译：引导和传递系统检测和治疗心肌梗死区域
公开(公告)号：WO2007053298A2
公开(公告)日：2007-05-10
申请号：PCT/US2006/040682
申请日：2006-10-13
申请人： CARDIAC PACEMAKERS, INC. , PASTORE, Joseph, M. , SALO, Rodney W. , HEIL, JR., Ronald W. , WESTLUND, Randy
发明人： PASTORE, Joseph, M. , SALO, Rodney W. , HEIL, JR., Ronald W. , WESTLUND, Randy
IPC分类号： A61N1/05
CPC分类号： A61N1/0587 , A61N1/059 , A61N1/3627
摘要： A method includes mounting an anchor member to a surface of a heart, the anchor member having a tension member coupled to the anchor member, advancing a lead body along the tension member, the lead body including a plurality of electrodes disposed along the lead body, identifying an MI region of the heart, positioning the plurality of electrodes at or near the MI region, affixing the tension member to the lead body to hold the electrodes in position, and delivering pulses through the plurality of electrodes to the heart.
摘要翻译：一种方法包括将锚固构件安装到心脏的表面，所述锚固构件具有联接到所述锚固构件的受拉构件，沿着所述受拉构件推进引线主体，所述引线主体包括多个沿着导联体设置的电极，识别心脏的MI区域，将多个电极定位在或靠近MI区域，将张力构件附连到导联体以将电极保持就位，并且通过多个心脏电极。

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