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    • 2. 发明申请
    • METHOD OF MODULATING A BEAM OF LIGHT AND OPTICAL EXTERNAL MODULATOR
    • 调制光束和光学外部调制器的方法
    • WO2009030916A8
    • 2009-09-17
    • PCT/GB2008003002
    • 2008-09-05
    • UNIV KENT CANTERBURYSHYQYRI HAXHAGORMAN TERRY
    • SHYQYRI HAXHAGORMAN TERRY
    • G02F1/225G02B6/12
    • G02F1/225G02F2001/212
    • An optical external modulator, includes a substrate (1), provided with an optical channel waveguide circuit. The optical channel waveguide circuit has an optical input (2) and an optical output (3), and includes at least a first junction (5), at which a waveguide channel (4) splits into multiple outgoing waveguide channels (6,7) forming arms of an interferometer, at least sections (13, 16) of two of the multiple outgoing waveguide channels (6,7) adjacent the first junction (5) defining a plane in which they lie, and at least a second junction (8), at which multiple incoming waveguide channels (6,7) forming arms of an interferometer combine to allow optical beams directed towards the optical output (3) to recombine. The second junction (8) is positioned at a distance from the plane in a transverse direction thereto.
    • 一种光学外部调制器,包括设置有光学通道波导电路的基板(1)。 光通道波导电路具有光输入(2)和光输出(3),并且至少包括第一结(5),在该第一结处,波导通道(4)分裂成多个出射波导通道(6,7) 形成干涉仪的臂,邻近第一结(5)的多个出射波导通道(6,7)中的两个的至少部分(13,16)限定它们所处的平面,以及至少第二结(8 ),在该处,形成干涉仪的臂的多个进入波导通道(6,7)结合以允许指向光输出(3)的光束重新结合。 第二接合部(8)定位在与平面相距一个横向的距离处。
    • 4. 发明申请
    • CAMERA ADAPTER BASED OPTICAL IMAGING APPARATUS
    • 基于摄像机适配器的光学成像设备
    • WO2009098516A3
    • 2009-10-22
    • PCT/GB2009050118
    • 2009-02-06
    • UNIV KENT CANTERBURYADRIAN PODOLEANU
    • ADRIAN PODOLEANU
    • G02B21/00G01B9/00
    • H04N5/232A61B3/102A61B3/14G01B9/02007G01B9/0203G01B9/02049G01B9/02069G01B9/02079G01B9/02091G01B2290/35G01B2290/70G02B21/0056G02B21/0064H04N5/2252H04N5/33
    • The invention describes several embodiments of an adapter which can make use of the devices in any commercially available digital cameras to accomplish different functions, such as a fundus camera, as a microscope or as an en-face optical coherence tomography (OCT) to produce constant depth OCT images or as a Fourier domain (channelled spectrum) optical coherence tomography to produce a reflectivity profile in the depth of an object or cross section OCT images, or depth resolved volumes,. The invention admits addition of confocal detection and provides simultaneous measurements or imaging in at least two channels, confocal and OCT, where the confocal channel provides an en-face image simultaneous with the acquisition of OCT cross sections, to guide the acquisition as well as to be used subsequently in the visualisation of OCT images.Different technical solutions are provided for the assembly of one or two digital cameras which together with such adapters lead to modular and portable high resolution imaging systems which can accomplish various functions with a minimum of extra components while adapting the elements in the digital camera. The cost of such adapters is comparable with that of commercial digital cameras, i.e. the total cost of such assemblies of commercially digital cameras and dedicated adapters to accomplish high resolution imaging are at a fraction of the cost of dedicated stand alone instruments. Embodiments and methods are presented to employ colour cameras and their associated optical sources to deliver simultaneous signals using their colour sensor parts to provide spectroscopic information, phase shifting interferometry in one step, depth range extension, polarisation, angular measurements and spectroscopic Fourier domain (channelled spectrum) optical coherence tomography in as many spectral bands simultaneously as the number of colour parts of the photodetector sensor in the digital camera. In conjunction with simultaneous acquisition of a confocal image, at least 4 channels can simultaneously be provided using the three color parts of conventional color cameras to deliver three OCT images in addition to the confocal image.
    • 本发明描述了适配器的几个实施例,该适配器可以利用任何市售数字照相机中的装置来完成不同的功能,诸如眼底照相机,显微镜或作为光学相干断层扫描(OCT)以产生恒定 深度OCT图像或作为傅立叶域(通道光谱)光学相干断层扫描术来产生物体或横截面OCT图像或深度分辨体积的深度中的反射率分布。 本发明允许增加共焦检测并且在至少两个通道中共焦和OCT提供同时测量或成像,其中共焦通道提供与OCT截面的采集同时的正面图像,以指导采集以及 随后用于OCT图像的可视化。为装配一个或两个数码相机提供了不同的技术解决方案,这些相机与这些适配器一起导致模块化和便携式高分辨率成像系统,其能够以最少的额外组件实现各种功能,同时 调整数码相机中的元素。 这种适配器的成本与商用数码相机的成本相当,即商业数码相机和专用适配器的这些组件的总成本是完成高分辨率成像的总成本的一小部分是专用独立仪器的成本。 提出了实施例和方法以使用彩色摄像机及其相关联的光源来使用它们的颜色传感器部件来提供同时的信号,以提供光谱信息,一步中的相移干涉测量,深度范围扩展,偏振,角度测量和光谱傅里叶域(通道频谱 )光学相干层析成像,与数码相机中的光电探测器传感器的彩色部分的数量一样多。 结合共焦图像的同时采集,可以使用常规彩色相机的三个颜色部分同时提供至少4个通道,以提供除共焦图像之外的三个OCT图像。
    • 5. 发明申请
    • MOLECULARLY IMPRINTED POLYMERS FOR THE CAPTURE OF BIOTIN
    • 用于生物吸收的分子印迹聚合物
    • WO2014030002A3
    • 2014-07-10
    • PCT/GB2013052214
    • 2013-08-22
    • UNIV KENT CANTERBURY
    • HALL ANDREW
    • C07D401/14C07D401/12C07D495/04C08F226/06G01N33/50
    • C08F222/14C07D213/75C08F226/06G01N33/82
    • The present invention refers to new classes of polymerisable monomers targeting biotin, a biotin derivative, a biotin analogue or a biotinylated molecule and related structures, as well as molecularly imprinted polymers obtainable by polymerisation of at least one of these monomers and at least one cross-linking monomer in the presence of a suitable template molecule. The obtained polymers may be used for separation of biotin and related small molecules, together with larger biotinylated molecules of biological origin, e.g. proteins, from complex mixtures. The monomer comprises i) an isophthalic acid derivative or a pyridine-2,6-dicarboxylic acid derivative and ii) a vinyl-2- aminopyridine derivative
    • 本发明涉及靶向生物素,生物素衍生物,生物素类似物或生物素化分子和相关结构的新类型的可聚合单体,以及通过这些单体中的至少一种的聚合可获得的分子印迹聚合物, 在合适的模板分子存在下连接单体。 所获得的聚合物可用于生物素和相关小分子的分离,以及生物来源的较大生物素化分子,例如。 蛋白质,来自复杂的混合物。 单体包括i)间苯二甲酸衍生物或吡啶-2,6-二羧酸衍生物,和ii)乙烯基-2-氨基吡啶衍生物
    • 7. 发明申请
    • INTEGRATED CIRCUIT WITH DEBUG SUPPORT INTERFACE
    • 集成电路与调试支持接口
    • WO2005059578A3
    • 2006-05-11
    • PCT/GB2004005014
    • 2004-11-29
    • UNIV KENT CANTERBURYMCDONALD-MAIER KLAUS DIETERHOPKINS ANDREW BRIAN THOMAS
    • MCDONALD-MAIER KLAUS DIETERHOPKINS ANDREW BRIAN THOMAS
    • G01R31/317G01F11/36
    • G01R31/31728G01R31/31705G06F11/3648H01L2224/05554H01L2224/16145H01L2224/48145H01L2224/48247H01L2924/00012
    • A high speed debug support interface has circuits to interface on-chip debug support circuits to a high bandwidth communications port means located on the surface of a system integrated circuit (101) and to on-chip debug support circuits (100). The communication port means can be realised by bonding or integrating special sender and or receiver cells preferably optical sender cells (103) and or optical receiver cells (110) onto the surface of the system integrated circuit (101). The high speed debug support interface communicates. with on-chip or in-assembly debug support circuits and an external development tool (108) to permit hardware and software related debugging and development activities, including program tracing, data tracing and memory substitution. The high speed debug support interface has circuits to interface on-chip debug support circuits to system resources such as memory located within. the device assembly (102) and connected by the system interconnect.
    • 高速调试支持接口具有将片上调试支持电路接口到位于系统集成电路(101)的表面上的高带宽通信端口装置和片上调试支持电路(100)的电路。 通信端口装置可以通过将特别的发送器和/或接收器单元优选地将光学发送器单元(103)和/或光学接收器单元(110)结合或集成到系统集成电路(101)的表面上来实现。 高速调试支持接口进行通信。 具有片上或组装调试支持电路和外部开发工具(108),允许与软件相关的调试和开发活动,包括程序跟踪,数据跟踪和内存替换。 高速调试支持接口具有将片上调试支持电路连接到系统资源(如位于内部的存储器)的电路。 所述设备组件(102)并且由所述系统互连连接。