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1. 发明申请

WO2007133732A3 DNA RECOMBINATION JUNCTION DETECTION 审中-公开
标题翻译： DNA重组接头检测
公开(公告)号：WO2007133732A3
公开(公告)日：2008-04-03
申请号：PCT/US2007011523
申请日：2007-05-11
申请人： CEPHEID , ZHANG JIAN PING , FRIEDLANDER ERNEST JAY , RUHFEL ROBERT , SWENSON DAVID DOUGLAS , WORTMAN ALAN THOMAS
发明人： ZHANG JIAN PING , FRIEDLANDER ERNEST JAY , RUHFEL ROBERT , SWENSON DAVID DOUGLAS , WORTMAN ALAN THOMAS
IPC分类号： C12Q1/68
CPC分类号： C12Q1/689 , C12Q1/6858 , C12Q2537/162 , C12Q2537/161
摘要： The present invention provides methods, compositions and kits for detecting the presence or absence of an integrated insertion polynucleotide.
摘要翻译：本发明提供用于检测整合的插入多核苷酸的存在或不存在的方法，组合物和试剂盒。

2. 发明申请

WO2007149903A2 MULTI-STAGE AMPLIFICATION REACTIONS BY CONTROL OF SEQUENCE REPLICATION TIMES 审中-公开
标题翻译：通过控制序列复制时间的多级放大反应
公开(公告)号：WO2007149903A2
公开(公告)日：2007-12-27
申请号：PCT/US2007/071641
申请日：2007-06-20
申请人： CEPHEID , KOZMA, Lynn , SWENSON, David
发明人： KOZMA, Lynn , SWENSON, David
CPC分类号： C12Q1/6851 , C12Q1/686 , C12Q2537/143 , C12Q2527/113 , C12Q2527/107 , C12Q2561/113 , C12Q2525/186 , C12Q2537/149 , C12Q2527/101
摘要： The present invention provides methods and kits for conducting multiplex nucleic acid amplification reactions by controlling target sequence replication times. In one aspect, such control is exerted by selecting different lengths of target polynucleotides for amplification. In another aspect, control is exerted by providing sequence-specific polymerase inhibitors, such as specific blocking oligonucleotides. In accordance with the invention, multiple target polynucleotides can be sequentially amplified in an amplification reaction conducted in different stages, wherein amplification of sequences with longer replication times is permitted in one stage but precluded in other stages by modifying polymerase extension times in the course of the reaction.
摘要翻译：本发明提供了通过控制靶序列复制时间进行多重核酸扩增反应的方法和试剂盒。在一个方面，通过选择不同长度的靶多核苷酸进行扩增来发挥这种控制。另一方面，通过提供序列特异性聚合酶抑制剂，例如特异性阻断寡核苷酸来进行对照。根据本发明，可以在不同阶段进行的扩增反应中顺序扩增多个靶多核苷酸，其中一个阶段允许扩增具有较长复制时间的序列，但是在其他阶段通过在反应。

3. 发明申请

WO2005091990A3 METHOD AND APPARATUS FOR IMPROVED PROCESSING WITH A GAS-CLUSTER ION BEAM 审中-公开
标题翻译：用于气体聚集离子束改进处理的方法和装置
公开(公告)号：WO2005091990A3
公开(公告)日：2006-03-16
申请号：PCT/US2005008983
申请日：2005-03-18
申请人： EPION CORP , SWENSON DAVID R , HAUTALA JOHN J , GWINN MATTHEW C , MACK MICHAEL E , TABAT MARTIN E
发明人： SWENSON DAVID R , HAUTALA JOHN J , GWINN MATTHEW C , MACK MICHAEL E , TABAT MARTIN E
IPC分类号： H01J27/00 , H01J27/02 , H01J37/305
CPC分类号： H01J27/026 , H01J37/3056 , H01J2237/0812 , H01J2237/188 , H01J2237/3151
摘要： Apparatus and methods for improving processing of workpieces with gas-cluster ion beams and modifying the gas-cluster ion energy distribution in the GCIB. In a reduced-pressure environment, generating an energetic gas-cluster ion beam and subjecting the beam to increased pressure region.
摘要翻译：用气团聚合离子束改善工件加工并改进GCIB中气团离子能量分布的装置和方法。在减压环境中，产生高能气体团簇离子束，并使束受到增加的压力区域。

4. 发明申请

WO2005091990A2 METHOD AND APPARATUS FOR IMPROVED PROCESSING WITH A GAS-CLUSTER ION BEAM 审中-公开
标题翻译：用于气体聚集离子束改进处理的方法和装置
公开(公告)号：WO2005091990A2
公开(公告)日：2005-10-06
申请号：PCT/US2005/008983
申请日：2005-03-18
申请人： EPION CORPORATION , SWENSON, David, R. , HAUTALA, John, J. , GWINN, Matthew, C. , MACK, Michael, E. , TABAT, Martin, E.
发明人： SWENSON, David, R. , HAUTALA, John, J. , GWINN, Matthew, C. , MACK, Michael, E. , TABAT, Martin, E.
IPC分类号： H01J27/00 , H01J27/02 , H01J37/305
CPC分类号： H01J27/026 , H01J37/3056 , H01J2237/0812 , H01J2237/188 , H01J2237/3151
摘要： Apparatus and methods for improving processing of workpieces with gas-cluster ion beams and modifying the gas-cluster ion energy distribution in the GCIB. In a reduced-pressure environment, generating an energetic gas-cluster ion beam and subjecting the beam to increased pressure region.
摘要翻译：用气团聚合离子束改善工件加工并改进GCIB中气团离子能量分布的装置和方法。在减压环境中，产生高能气体团簇离子束，并使束受到增加的压力区域。

5. 发明申请

WO2016109691A1 DEVICES AND METHODS FOR MOLECULAR DIAGNOSTIC TESTING 审中-公开
标题翻译：用于分子诊断测试的装置和方法
公开(公告)号：WO2016109691A1
公开(公告)日：2016-07-07
申请号：PCT/US2015/068101
申请日：2015-12-30
申请人： ANDREYEV, Boris , CIOPYK, Brian , DE LA ZERDA, Adam , MORAVICK, Keith , SWENSON, David , LONEY, Gregory , CHING, Jesus , KELLY, Colin , BRIONES, Victor , CHU, Steve , HUANG, Helen
发明人： ANDREYEV, Boris , CIOPYK, Brian , DE LA ZERDA, Adam , MORAVICK, Keith , SWENSON, David , LONEY, Gregory , CHING, Jesus , KELLY, Colin , BRIONES, Victor , CHU, Steve , HUANG, Helen
IPC分类号： C12P19/34
CPC分类号： B01L3/502715 , B01L3/5027 , B01L3/5029 , B01L3/527 , B01L7/52 , B01L7/525 , B01L2200/025 , B01L2200/028 , B01L2200/0647 , B01L2200/0684 , B01L2200/0689 , B01L2200/10 , B01L2300/0627 , B01L2300/0654 , B01L2300/0672 , B01L2300/0681 , B01L2300/0867 , B01L2300/0883 , B01L2300/18 , B01L2300/1822 , B01L2300/1844 , B01L2400/0457 , B01L2400/0478 , B01L2400/0487 , B01L2400/0605 , B01L2400/0611 , B01L2400/0644
摘要： A hand-held molecular diagnostic test device includes a housing, an amplification (or PCR) module, and a detection module. The amplification module is configured to receive an input sample, and defines a reaction volume. The amplification module includes a heater such that the amplification module can perform a polymerase chain reaction (PCR) on the input sample. The detection module is configured to receive an output from the amplification module and a reagent formulated to produce a signal that indicates a presence of a target amplicon within the input sample. The amplification module and the detection module are integrated within the housing.
摘要翻译：手持式分子诊断测试装置包括壳体，扩增（或PCR）模块和检测模块。放大模块被配置为接收输入样本，并且定义反应体积。扩增模块包括加热器，使得扩增模块可以对输入的样品进行聚合酶链式反应（PCR）。检测模块被配置为接收来自放大模块的输出和被配制为产生指示输入样本内目标扩增子存在的信号的试剂。放大模块和检测模块集成在外壳内。

6. 发明申请

WO2013112940A3 SOCIAL FAMILY NETWORKING PLATFORM 审中-公开
标题翻译：社会家庭网络平台
公开(公告)号：WO2013112940A3
公开(公告)日：2015-06-18
申请号：PCT/US2013023301
申请日：2013-01-25
申请人： SOCIALPARENT INC , RAJI REZA , GUTT GERRY , SWENSON DAVID
发明人： RAJI REZA , GUTT GERRY , SWENSON DAVID
IPC分类号： G06F17/30 , G06F7/00 , G06F15/16
CPC分类号： H04L65/403 , H04L67/30 , H04W4/206
摘要： Embodiments provide a database that includes family models. Each family model includes family data that is aggregated data of members of a family. The family data includes for each family member data of at least one of name, age, gender, education, interests, and memberships. Each family model comprises information that defines relationships between other families based on the family data. A platform includes a processor networked to the database and a social application executing on the processor. The platform, in response to a request to create the family model, collects the family data and generates the family model to include the family data. The platform enables the families to manage and interact using a collection of group types.
摘要翻译：实施例提供了包括家庭模型的数据库。每个家庭模式都包含家庭成员的家庭数据，这是家庭成员的汇总数据。家庭数据包括每个家庭成员至少姓名，年龄，性别，教育，兴趣和会员资格的数据。每个家庭模型包括基于家庭数据定义其他家庭之间的关系的信息。平台包括与数据库联网的处理器和在处理器上执行的社交应用程序。该平台响应于创建家庭模式的请求，收集家庭数据并生成家庭模型以包括家庭数据。该平台使家庭能够使用组类型的集合进行管理和交互。

7. 发明申请

WO2012082142A1 SENSING SHOCK DURING WELL PERFORATING 审中-公开
标题翻译：感觉冲击在良好的性能
公开(公告)号：WO2012082142A1
公开(公告)日：2012-06-21
申请号：PCT/US2010/061102
申请日：2010-12-17
申请人： HALLIBURTON ENERGY SERVICES, INC. , RODGERS, John , SERRA, Marco , SWENSON, David , LINYAEV, Eugene , GLENN, Timothy, S. , LE, Cam
发明人： RODGERS, John , SERRA, Marco , SWENSON, David , LINYAEV, Eugene , GLENN, Timothy, S. , LE, Cam
IPC分类号： E21B47/00 , E21B47/01
CPC分类号： E21B43/119 , E21B47/06
摘要： A shock sensing tool for use with well perforating can include a generally tubular structure which is fluid pressure balanced, at least one strain sensor which senses strain in the structure, and a pressure sensor which senses pressure external to the structure. A well system can include a perforating string including multiple perforating guns and at least one shock sensing tool, with the shock sensing tool being interconnected in the perforating string between one of the perforating guns and at least one of : a) another of the perforating guns, and b) a firing head.
摘要翻译：用于良好穿孔的冲击感测工具可以包括流体压力平衡的大体上管状的结构，感测结构中的应变的至少一个应变传感器和感测结构外部的压力的压力传感器。井系统可以包括包括多个穿孔枪和至少一个冲击感测工具的穿孔绳，其中所述冲击感测工具在所述穿孔枪之间的穿孔线之间互连，所述穿孔枪之一在所述射孔枪之中，并且至少一个：a）另一个穿孔枪，和b）烧焦头。

8. 发明申请

WO2007130951A2 METHODS AND APPARATUS FOR SEQUENTIAL AMPLIFICATION REACTIONS 审中-公开
标题翻译：用于顺序放大反应的方法和装置
公开(公告)号：WO2007130951A2
公开(公告)日：2007-11-15
申请号：PCT/US2007/067895
申请日：2007-05-01
申请人： CEPHEID , SMITH, Joseph, H. , PERSING, David, H. , WORTMAN, Alan , CHANG, Ronald , SWENSON, David
发明人： SMITH, Joseph, H. , PERSING, David, H. , WORTMAN, Alan , CHANG, Ronald , SWENSON, David
IPC分类号： C12Q1/68
CPC分类号： C12Q1/686 , B01L3/502738 , B01L7/52 , B01L2300/0654 , B01L2300/0816 , B01L2300/0864 , B01L2400/0644 , C12Q1/6848 , C12Q1/6851 , C12Q1/689 , C12Q2565/629 , C12Q2547/101 , C12Q2537/149 , C12Q2537/143 , C12Q2565/101 , C12Q2527/107
摘要： The invention provides methods and apparatus for carrying out multiple amplification reactions in a single reaction chamber by successive cycles of loading reaction mixture, amplifying, and removing spent reaction mixture in a fluidly closed reaction system. In particular, the present invention allows amplification of a plurality of target polynucleotides from a single sample by carrying out under closed-loop control successive amplifications of different target polynucleotides from different portions of the sample.
摘要翻译：本发明提供了在单个反应室中进行多次扩增反应的方法和装置，其通过连续循环的负载反应混合物，在流体封闭的反应体系中放大和除去废反应混合物。特别地，本发明允许通过在闭环控制下从样品的不同部分连续扩增不同靶多核苷酸而从单个样品扩增多个靶多核苷酸。

9. 发明申请

WO2004007972A2 CONNECTING ROD ASSEMBLY 审中-公开
标题翻译：连杆组件
公开(公告)号：WO2004007972A2
公开(公告)日：2004-01-22
申请号：PCT/US2003/021780
申请日：2003-07-11
申请人： SWENSON, David, C.
发明人： SWENSON, David, C.
IPC分类号： F15B
CPC分类号： F16C7/023
摘要： A connecting rod assembly that is provided with an integral pre-set tension that is helpful in the use of the connecting rod assembly when installed in an internal combustion engine.
摘要翻译：
连杆组件，带有整体预设张力，有助于在安装在内燃机中时使用连杆组件。

10. 发明申请

WO2013112940A2 SOCIAL FAMILY NETWORKING PLATFORM 审中-公开
标题翻译：社会家庭网络平台
公开(公告)号：WO2013112940A2
公开(公告)日：2013-08-01
申请号：PCT/US2013/023301
申请日：2013-01-25
申请人： SOCIALPARENT, INC. , RAJI, Reza , GUTT, Gerry , SWENSON, David
发明人： RAJI, Reza , GUTT, Gerry , SWENSON, David
IPC分类号： H04L29/06
CPC分类号： H04L65/403 , H04L67/30 , H04W4/21
摘要： Embodiments provide a database that includes family models. Each family model includes family data that is aggregated data of members of a family. The family data includes for each family member data of at least one of name, age, gender, education, interests, and memberships. Each family model comprises information that defines relationships between other families based on the family data. A platform includes a processor networked to the database and a social application executing on the processor. The platform, in response to a request to create the family model, collects the family data and generates the family model to include the family data. The platform enables the families to manage and interact using a collection of group types.
摘要翻译：实施例提供了包括家庭模型的数据库。每个家庭模式都包含家庭成员的家庭数据，这是家庭成员的汇总数据。家庭数据包括每个家庭成员至少姓名，年龄，性别，教育，兴趣和会员资格的数据。每个家庭模型包括基于家庭数据定义其他家庭之间的关系的信息。平台包括与数据库联网的处理器和在处理器上执行的社交应用程序。该平台响应于创建家庭模式的请求，收集家庭数据并生成家庭模型以包括家庭数据。该平台使家庭能够使用组类型的集合进行管理和交互。

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