专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2019092748A1 A NANO FIBER BASED OSTEO-CONDUCTIVE RESORBABLE PATCH FOR BONE REGENERATION 审中-公开
公开(公告)号：WO2019092748A1
公开(公告)日：2019-05-16
申请号：PCT/IN2018/050732
申请日：2018-11-12
申请人： AGRAWAL, Ghanshyam Das
发明人： AGRAWAL, Ghanshyam Das
IPC分类号： A61L27/46 , A61L27/58
CPC分类号： A61L27/46 , A61L27/58 , A61L2400/12 , A61L2430/02
摘要： This invention is directed to a nano fiber based osteo-conductive resorbable patch for bone regeneration comprising of Calcium phosphate salt, Strontium salt and Cupric salt. It is associated with the following advantageous features:- - Acts as medium for breeding/anchoring of osteoblasts - Forms a minute honeycomb structure for proliferation of osteoblasts - Beta TCP /HA acts as osteoconductive material, which conducts bone formation by virtue of calcium and phosphate ions. - Strontium limits activity of osteoclasts, thereby increasing bone formation speed. - Copper helps in formation of blood vessels, thereby further aiding bone formation activity. It has been used in several children to repair cranial defects and found to be highly successful. It has also been implemented in detail segment for many purposes.

2. 发明申请

WO2018164594A1 METHOD OF MANUFACTURING COMPOSITE BONE IMPLANTS, METHOD OF MANUFACTURING POWDERED RAW MATERIAL FOR SUCH IMPLANTS, SUCH POWDERED RAW MATERIAL AND BONE IMPLANT 审中-公开
公开(公告)号：WO2018164594A1
公开(公告)日：2018-09-13
申请号：PCT/PL2018/050008
申请日：2018-03-05
申请人： INSTYTUT WYSOKICH CIŚNIEŃ POLSKIEJ AKADEMII NAUK
发明人： MAŁYSA, Maria , CHUDOBA, Tadeusz , PIETRZYKOWSKA, Elżbieta , CHODARA, Agnieszka , LOJKOWSKI, Witold , KROPIWNICKI, Jacek , CHARKIEWICZ, Michał
IPC分类号： A61L27/36 , A61L27/42
CPC分类号： A61L27/425 , A61L27/3604 , A61L27/3691 , A61L2400/12 , A61L2430/02
摘要： The method of implant production includes a step of preparing a raw material in powdered form and a step of forming of the implant by pressing. In the material preparation stage fragments of the natural silk fibre are cryogenically grinded and mixed with powdered synthetic nanometric hydroxyapatite. The proportion of hydroxyapatite in the powdered raw material is from 70% to 95% by weight. Composite powder, which is the raw material for implant formation, contains hydroxyapatite with a particle size of not more than 80 nm and a molar ratio of calcium to phosphorus in the range from 1.57 to 1.67. The composite bone implant contains fibroin and from 70% to 95% by weight of hydroxyapatite with a particle size of not more than 80 nm, and a molar ratio of calcium to phosphorus from 1.57 to 1.65. The Young's modulus of the implants material is in the range from 7.5 to 9.5 GPa, its total porosity ranges from 10 to 20%. The bending strength of such an implant is at least 30 MPa, and its compression strength is at least 100 MPa.

3. 发明申请

WO2018081159A1 BIOMIMETIC MULTILAYER COMPOSITIONS 审中-公开
标题翻译：生物多样性多层组合物
公开(公告)号：WO2018081159A1
公开(公告)日：2018-05-03
申请号：PCT/US2017/058134
申请日：2017-10-24
申请人： TRUSTEES OF TUFTS COLLEGE , MASSACHUSETTS INSTITUTE OF TECHNOLOGY
发明人： KAPLAN, David L. , BUEHLER, Markus J. , LING, Shengjie
IPC分类号： A61L27/22 , A61L27/24 , A61L27/36 , A61L27/56 , D01B7/00
CPC分类号： B01D69/144 , A61L27/3604 , A61L27/46 , A61L27/56 , A61L2400/12 , B01D67/0079 , B01D69/12 , B01D71/02 , B01D71/74 , C02F1/44 , C02F2101/22 , D01B7/00
摘要： The present invention provides, inter alia, compositions including at least one pliable layer comprising a plurality of silk fibroin nanofibrils, and at least one rigid layer comprising a plurality of mineral crystals, wherein each rigid layer is associated with at least one pliable layer, as well as methods for the production and use thereof.
摘要翻译：本发明尤其提供了包含至少一个包含多个丝素蛋白纳米原纤维的柔韧层和至少一个包含多个矿物晶体的刚性层的组合物，其中每个刚性层都是缔合的至少有一层柔韧层，以及生产和使用它的方法。

4. 发明申请

WO2017223261A2 HYDROGELS, ARTICLES COMPRISING HYDROGELS, AND METHODS THEREOF 审中-公开
标题翻译：水凝胶，包含水凝胶的制品及其方法
公开(公告)号：WO2017223261A2
公开(公告)日：2017-12-28
申请号：PCT/US2017/038651
申请日：2017-06-22
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： LIPSCOMB, Corinne E. , YOUNG, Alexi J.
CPC分类号： A61L15/60 , A61L15/18 , A61L15/225 , A61L31/02 , A61L31/048 , A61L31/10 , A61L31/145 , A61L2400/12 , C08J2205/022 , C08L33/10 , C08L33/26 , C08L2203/02 , C09D133/26 , C08L33/08 , C08L1/02 , C08K3/34
摘要： Described herein is a hydrogel having a water content of at least 10 wt%. The hydrogel is derived from an aqueous composition comprising: a hydrophilic monomer comprising at least one of (meth)acrylate and (meth)acrylamide; at least 0.1 wt% of a water-swellable clay; at least 0.1 wt% cellulose nanocrystals; and a photoinitiator. Also disclosed herein are methods of making hydrogels and articles thereof.
摘要翻译：本文描述了水含量为至少10重量％的水凝胶。该水凝胶衍生自水性组合物，该水性组合物包含：包含（甲基）丙烯酸酯和（甲基）丙烯酰胺中的至少一种的亲水性单体; 至少0.1重量％的水溶胀性粘土; 至少0.1重量％的纤维素纳米晶体; 和光引发剂。本文还公开了制造水凝胶及其制品的方法。

5. 发明申请

WO2017201259A1 OSTEOINDUCTIVE NANOFIBER SCAFFOLD FOR BONE REGENERATION 审中-公开
标题翻译：骨再生的骨诱导纳米纤维支架
公开(公告)号：WO2017201259A1
公开(公告)日：2017-11-23
申请号：PCT/US2017/033286
申请日：2017-05-18
申请人： RTI SURGICAL, INC.
发明人： LOGUIDICE, Amanda B. , HOULIHAN, Alison
IPC分类号： A61L27/26 , A61L27/32 , A61L27/38 , A61L27/56 , A61L27/58
CPC分类号： A61L27/46 , A61L27/18 , A61L27/26 , A61L27/32 , A61L27/3821 , A61L27/3834 , A61L27/3847 , A61L27/446 , A61L27/54 , A61L27/56 , A61L27/58 , A61L2300/106 , A61L2300/112 , A61L2300/412 , A61L2400/12 , A61L2430/02 , D01D5/0007 , C08L33/08 , C08L67/04 , C08L71/02
摘要： The present application is directed to the field of scaffolds for tissue engineering. The scaffolds are typically comprised of nanofibers and are optionally biomineralized. The present application provides a process for forming nanofibrous materials via electrospinning and for biomineralizing such materials. The scaffolds of the present application can be biomineralized and contain a plurality of cells either on or within the scaffold, resulting in synthetic, bioresorbable scaffolds that can be used in various biomedical applications, such as for bone regeneration.
摘要翻译：本申请涉及用于组织工程的支架领域。支架通常由纳米纤维组成，并且任选生物矿化。本申请提供了一种通过静电纺丝形成纳米纤维材料并对这些材料进行生物矿化的方法。本申请的支架可以是生物矿化的，并且在支架上或支架内包含多个细胞，产生合成的，生物可吸收的支架，其可以用于各种生物医学应用，例如用于骨再生。

6. 发明申请

WO2017196287A1 ГИДРОГЕЛЕВАЯ ПОВЯЗКА ДЛЯ ЛЕЧЕНИЯ ОЖОГОВЫХ РАН И ТРОФИЧЕСКИХ ЯЗВ И СПОСОБ ЕЕ ИЗГОТОВЛЕНИЯ 审中-公开
标题翻译：对烧伤创面和营养性溃疡及其制造方法的处理水凝胶敷料THEREOF
公开(公告)号：WO2017196287A1
公开(公告)日：2017-11-16
申请号：PCT/UA2016/000095
申请日：2016-07-29
申请人： ТАВОКИН, Владимир Викторович
发明人： ТАВОКИН, Владимир Викторович
IPC分类号： A61F13/00 , A61L15/24 , A61L15/42 , A61L15/60 , A61L15/44 , B82Y5/00
CPC分类号： A61F13/00063 , A61F13/00017 , A61F2013/00157 , A61L15/24 , A61L15/44 , A61L15/60 , A61L2400/12 , B82Y5/00 , C08L33/26
摘要： Изобретение относится к медицине. Гидрогелевая повязка для лечения ожоговых ран и трофических язв содержит закрепленную на сетке гелеобразную композицию на основе акриламида и воды. Сетка изготовлена термообработанной из ниток на основе синтетических волокон, в частности, полипропиленовых волокон. Повязка имеет повышенную прочность, повышенный срок пребывания на ране, а также заранее заданную эластичность и уменьшает травмирование раны. Способ изготовления гидрогелевой повязки включает изготовление гелеобразующей композиции и соединение композиции с сеткой. Сетку предварительно очищают, размещают в растянутом состоянии и осуществляют термообработку нагреванием до 40-140°С в течение 20-45 минут, охлаждают и совершают активацию сетки в среде пероксида, озона, оксида хрома или кислоты. Далее сетку размещают в форме, в которую заливают гелеобразующую композицию, удаляют воздух из формы и выдерживают ее в течение 14-15 часов при 75-85°С до формирования пластины, которую промывают, обезвоживают и стерилизуют с получением повязки.
摘要翻译：
本发明涉及医学。用于治疗烧伤和营养性溃疡的水凝胶敷料含有基于丙烯酰胺和固定在网上的水的凝胶状组合物。网格由基于合成纤维，特别是聚丙烯纤维的线进行热处理制成。敷料具有增加的强度，增加伤口留下的时间以及预定的弹性并减少对伤口的伤害。用于制造水凝胶敷料的方法包括制造凝胶组合物和具有网孔的组合物的化合物。目预先纯化，被放置在一个拉伸状态和热处理是通过加热进行，以40-140度＆; 20-45分钟C，冷却并在过氧化物介质筛网，臭氧，氧化铬或酸进行活化。接着将网放置在其中胶凝组合物倒入一形式中，空气被从模具中取出，并保持它为14-15小时，在75-85℃下; C到形成板，将其洗涤，脱水和灭菌，得到敷料。

7. 发明申请

WO2017171341A2 친수성 폴리우레탄 나노섬유 및 그의 제조방법 审中-公开
标题翻译：亲水性聚氨酯纳米纤维及其制造方法
公开(公告)号：WO2017171341A2
公开(公告)日：2017-10-05
申请号：PCT/KR2017/003298
申请日：2017-03-28
申请人： 경북대학교 산학협력단
发明人： 최진현 , 김우진
IPC分类号： D04H1/728 , D04H1/4358 , D01D5/00 , B01D39/16 , A61F13/02 , A61M1/02 , A61M1/34 , A61L15/22
CPC分类号： A61F13/02 , A61F13/00017 , A61L15/22 , A61L15/26 , A61L2400/12 , A61M1/0088 , A61M1/02 , A61M1/34 , A61M1/3635 , B01D39/16 , B01D39/1623 , B01D2239/025 , B01D2239/0421 , C02F1/001 , C02F2305/08 , D01D5/0007 , D01D5/003 , D01D5/34 , D01F6/14 , D01F6/70 , D01F8/10 , D01F8/16 , D04H1/4358 , D04H1/728 , C08L75/04
摘要： 본 발명은 동축전기방사법을 통해 제조된 폴리우레탄/수용성 고분자 블렌드 나노섬유를 제조한 뒤 수용성 고분자를 물에 용해시켜 제거함으로써 친수성이 향상된 폴리우레탄 나노섬유를 제조하는 방법에 관한 것이다.
摘要翻译：
本发明的方法用于通过水溶性聚合物后的聚氨酯/水溶性聚合物共混物溶解除去，以制备通过在水同轴静电方法生产的纳米纤维制造的亲水性改进聚氨酯纳米纤维。

8. 发明申请

WO2017139357A1 DRUG ELUTING BALLOON 审中-公开
标题翻译：药物缓释气囊
公开(公告)号：WO2017139357A1
公开(公告)日：2017-08-17
申请号：PCT/US2017/016981
申请日：2017-02-08
申请人： ORBUSNEICH MEDICAL, INC.
发明人： COTTONE, Robert, J. , ROWLAND, Stephen
IPC分类号： A61M25/10 , A61L29/08 , A61L29/12 , A61L29/16 , A61L29/14
CPC分类号： A61M25/104 , A61L29/085 , A61L29/146 , A61L29/16 , A61L2300/416 , A61L2300/62 , A61L2400/12 , A61M2025/105
摘要： The present invention is an inflatable balloon which is enclosed by an expandable cover which becomes increasingly porous/permeable during expansion. The balloon is coated or enclosed with a matrix which contains a pharmaceutically active agent. During expansion of the balloon, the pharmaceutically active agent is released or extruded through the expandable coyer into a body cavity such as an artery or vein. The present invention also provides for a method of treating a disease or condition by delivering the inflatable balloon to a particular body cavity.
摘要翻译：本发明是一种可膨胀的气囊，其由可膨胀的盖所包围，该可膨胀的盖在膨胀期间变得越来越多孔/可渗透。球囊被包含或含有药物活性剂的基质包封。在球囊膨胀过程中，药物活性剂通过可膨胀的衣物释放或挤出进入体腔如动脉或静脉。本发明还提供了一种通过将可膨胀气囊递送至特定体腔来治疗疾病或病症的方法。

9. 发明申请

WO2017115018A1 A MEDICAL MULTI-LAYER PRODUCT COMPRISING NANOFIBRILLAR CELLULOSE AND METHOD FOR PREPARING THEREOF 审中-公开
标题翻译：包含纳米纤维素纤维的医用多层产品及其制备方法
公开(公告)号：WO2017115018A1
公开(公告)日：2017-07-06
申请号：PCT/FI2016/050938
申请日：2016-12-30
申请人： UPM-KYMMENE CORPORATION
发明人： KOSONEN, Mika , LUUKKO, Kari
IPC分类号： A61L15/22 , A61L15/28 , A61L15/60
CPC分类号： A61L15/28 , A61L15/60 , A61L27/20 , A61L27/52 , A61L27/60 , A61L2400/12 , C08L1/00
摘要： The present application provides a medical multi-layer product comprising a layer comprising nanofibrillar cellulose, and a layer of gauze. The present application also provides a medical product comprising the medical multi- layer product, and a cosmetic product comprising the medical multi-layer product. The present application also provides a method for preparing a medical multi-layer product, the method comprising providing a filter, providing a dispersion comprising nanofibrillar cellulose, providing a gauze, applying the dispersion onto the filter, applying the gauze onto the dispersion, and dewatering the structure through the filter to obtain the medical multi- layer product.
摘要翻译：本申请提供了一种医用多层产品，其包含含纳米原纤纤维素的层和一层纱布。本申请还提供了包含该医用多层产品的医疗产品以及包含该医用多层产品的化妆品。本申请还提供了用于制备医用多层产品的方法，所述方法包括提供过滤器，提供包含纳米纤维状纤维素的分散体，提供纱布，将分散体施加到过滤器上，将纱布施用到分散体上，以及脱水该结构通过过滤器获得医疗多层产品。

10. 发明申请

WO2017095240A1 LIGHT-ACTIVATED PREPARATION OF HYDROGELS 审中-公开
标题翻译：光活化制备水凝胶
公开(公告)号：WO2017095240A1
公开(公告)日：2017-06-08
申请号：PCT/NZ2016/050192
申请日：2016-12-02
申请人： LIM, Shen Khoon , WOODFIELD, Timothy Bryan Francis , BROWN, Gabriella Christina Johanna
发明人： LIM, Shen Khoon , WOODFIELD, Timothy Bryan Francis , BROWN, Gabriella Christina Johanna
IPC分类号： A61L27/52 , B01J23/46 , C08L5/10 , C08J3/24
CPC分类号： A61L27/52 , A61L27/38 , A61L27/54 , A61L27/56 , A61L2300/102 , A61L2300/414 , A61L2400/12 , A61L2430/06 , C08B37/0075 , C08J3/075 , C08J3/28 , C08J2305/10 , C08J2329/04 , C08J2389/00 , C08L5/10
摘要： A method for preparing a hydrogel comprising mixing a solution of a polymer with a photoinitiator, where the polymer comprises multiple subunits each having a non-aromatic unsaturated functional group, and irradiating the mixture with visible light to produce the hydrogel.
摘要翻译：制备水凝胶的方法包括将聚合物溶液与光引发剂混合，其中聚合物包含各自具有非芳族不饱和官能团的多个亚单元，并用可见光照射混合物以产生水凝胶。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式