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1. 发明申请

WO2016098113A1 ENDOVASCULAR STENT-GRAFT WITH FATIGUE-RESISTANT LATERAL TUBE 审中-公开
标题翻译：具有耐疲劳侧管的内部支架
公开(公告)号：WO2016098113A1
公开(公告)日：2016-06-23
申请号：PCT/IL2015/051221
申请日：2015-12-16
申请人： ENDOSPAN LTD.
发明人： MARMUR, Yaniv , NAE, Nir Shalom , SHALEV, Alon
IPC分类号： A61F2/07
CPC分类号： A61F2/91 , A61F2/07 , A61F2/848 , A61F2/89 , A61F2002/061
摘要： A stent-graft (20) comprises strut members (30) and a graft member (32), which is fixed to the strut members (30). The strut members (30) and the graft member (32) are arranged so as to define, when the stent-graft (20) is in a radially-expanded state: a main tube (40), which is shaped so as to define a main lumen (42); and a lateral tube (50), which (a) has (i) a distal end (52) and (ii) a proximal end (54) that is joined to a lateral wall (56) of the main tube (40) at a junction (60), (b) is shaped so as to define a lateral lumen (62) that is in fluid communication with the main lumen (42), and (c) defines a central longitudinal axis (64). The strut members (30) that define the lateral tube (50) are shaped so as to define two to four non-contiguous arcuate members (70), which (a) are centered around the central longitudinal axis (64), and (b) collectively subtend at least 150 degrees around the central longitudinal axis (64).
摘要翻译：支架移植物（20）包括固定到支柱构件（30）上的支柱构件（30）和移植构件（32）。支架构件（30）和移植构件（32）布置成当支架移植物（20）处于径向展开状态时限定：主管（40），其被成形为限定主管腔（42）; 和侧管（50），其中（a）具有（i）远端（52）和（ii）接近主管（40）的侧壁（56）的近端（54）（60），（b）成形为限定与主腔（42）流体连通的侧腔（62），（c）限定中心纵向轴线（64）。限定侧管（50）的支柱构件（30）成形为限定两个至四个不连续的弓形构件（70），其中（a）围绕中心纵向轴线（64）居中，并且（b ）围绕中心纵向轴线（64）共同对向至少150度。

2. 发明申请

WO2013171730A1 STENT-GRAFT WITH FIXATION ELEMENTS THAT ARE RADIALLY CONFINED FOR DELIVERY 审中-公开
标题翻译：具有固定元件的STENT-GRAFT被定义为交付
公开(公告)号：WO2013171730A1
公开(公告)日：2013-11-21
申请号：PCT/IL2012/000190
申请日：2012-05-15
申请人： ENDOSPAN LTD. , SHALEV, Alon
发明人： SHALEV, Alon
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61F2/07 , A61F2/82 , A61F2/966 , A61F2002/075 , A61F2002/8483
摘要： An endovascular stent-graft (10) is configured to assume a radially-compressed delivery state and a radially-expanded deployment state, and includes a flexible stent member (24), and a tubular fluid flow guide (26), which is attached to the stent member (24). The stent member (24) includes a generally circumferential section (40) that is shaped so as to define: (a) a plurality of first struts (42), (b) a plurality of second struts (43), and (c) a plurality of fixation members (44), which are coupled to respective ones of the first struts (42). The circumferential section (40) is configured such that (a) when the stent-graft (10) is in the delivery state, the second struts (43) radially constrain the fixation members (44), respectively, from protruding radially outward, and (b) when the stent-graft (10) is in the deployment state, the fixation members (44) are not radially-constrained by the second struts (43) and protrude radially outward.
摘要翻译：血管内支架移植物（10）构造成呈现径向压缩的递送状态和径向展开的展开状态，并且包括柔性支架构件（24）和管状流体流动引导件（26），其连接到支架构件（24）。支架构件（24）包括大致圆周的部分（40），其形状为：（a）多个第一支柱（42），（b）多个第二支柱（43）和（c）多个固定构件（44），其联接到所述第一支柱（42）中的相应的一个。圆周部分（40）被构造成使得（a）当支架移植物（10）处于输送状态时，第二支柱（43）分别径向限制固定构件（44）从径向向外突出，并且（b）当支架移植物（10）处于展开状态时，固定构件（44）不被第二支柱（43）径向约束并径向向外突出。

3. 发明申请

WO2013005207A1 STENT FIXATION WITH REDUCED PLASTIC DEFORMATION 审中-公开
标题翻译：具有减少塑性变形的STENT固定
公开(公告)号：WO2013005207A1
公开(公告)日：2013-01-10
申请号：PCT/IL2012/000269
申请日：2012-07-02
申请人： ENDOSPAN LTD. , SHALEV, Alon
发明人： SHALEV, Alon
IPC分类号： A61F2/82
CPC分类号： A61F2/945 , A61B2017/00867 , A61B2017/1107 , A61B2017/1135 , A61F2/064 , A61F2/852 , A61F2002/061 , A61F2002/072 , A61F2002/828 , A61F2250/0039 , A61F2250/0063
摘要： An endovascular stent system (10) includes first and second generally tubular stents An endovascular stent system (10) includes first and second generally tubular stents members (20, 22), which are shaped so as to define first and second interface sections (40, 42), respectively, which are securely coupleable to each other. The first interface section (40) is shaped so as to define an opening (44). The second interface section (42) is shaped so as to define a neck portion (50). When the first and second stent members (20, 22) are coupled together, the neck portion (50) is at least in part defined by:(a) first ones (72) of structural elements (70), positioned at respective first circumferential locations, which are configured to apply, to the opening (44), distally- and radially- outwardly-directed forces, without applying any proximally-directed forces, and (b) separate from the first structural elements (72), second ones (74) of the structural elements (70).
摘要翻译：血管内支架系统（10）包括第一和第二大体管状支架血管内支架系统（10）包括第一和第二大体管状支架构件（20,22），其被成形为限定第一和第二界面部分 42），它们彼此牢固地连接。第一界面部分（40）成形为限定开口（44）。第二接口部分（42）成形为限定颈部（50）。当第一和第二支架构件（20,22）联接在一起时，颈部（50）至少部分地由以下部分限定：（a）结构元件（70）的第一（72），其位于相应的第一周向位置，其构造成施加到开口（44），远端和径向向外的力，而不施加任何向近侧方向的力，以及（b）与第一结构元件（72），第二结构元件 74）的结构元件（70）。

4. 发明申请

WO2012049679A3 ACCELERATED BENCH-TESTING OF MEDICAL DEVICES 审中-公开
公开(公告)号：WO2012049679A3
公开(公告)日：2012-04-19
申请号：PCT/IL2011/000801
申请日：2011-10-10
申请人： ENDOSPAN LTD. , RAZ, Sagi , BENARY, Raphael , SHALEV, Alon
发明人： RAZ, Sagi , BENARY, Raphael , SHALEV, Alon
IPC分类号： G01F17/00 , G01F23/00
摘要： A biomedical tester includes a fluid-control container, shaped to define a fluid-control container port and a first interface surface defining fluid-control container apertures. A fluid controller is shaped to define a second interface surface defining controller ports. These elements and a motor are arranged to relative translation between the first and second interface surfaces; thereby effecting a time- varying overlap between subgroups of the system. Fixtures allow disposition therewithin of respective medical devices. Each of the fixtures includes one or more fixture first ports and fixture second ports. The fixture first ports are mounted in fluid Communication respective with the controller ports. A fluid pump includes first and second pump ports in fluid communication with the fixture second ports and the fluid-control container port, respectively.

5. 发明申请

WO2011080738A1 ENDOVASCULAR FLOW DIRECTION INDICATOR 审中-公开
标题翻译：内部流动指向指标
公开(公告)号：WO2011080738A1
公开(公告)日：2011-07-07
申请号：PCT/IL2010/001087
申请日：2010-12-27
申请人： ENDOSPAN LTD. , SHALEV, Alon , RAZ, Sagi
发明人： SHALEV, Alon , RAZ, Sagi
IPC分类号： A61B17/22 , A61D1/02
CPC分类号： A61F2/95 , A61B17/12109 , A61B17/12113 , A61B17/12118 , A61B17/1215 , A61B2017/1205 , A61B2090/0807 , A61B2090/376 , A61B2090/3966 , A61F2002/011
摘要： An endovascular tool (10) is provided, which includes a longitudinal delivery shaft (24) and a fin (20) coupled to the delivery shaft (24). The fin (20) is configured to assume (a) a compressed state for endoluminal delivery, and (b) an expanded state for endoluminal deployment, in which state the fin (20) is configured to pivot around an axis of rotation (18). Other embodiments are also described.
摘要翻译：提供了一种血管内工具（10），其包括纵向输送轴（24）和联接到输送轴（24）的翅片（20）。翅片（20）被配置为假设（a）用于腔内递送的压缩状态，和（b）用于腔内展开的膨胀状态，其中翅片（20）构造成围绕旋转轴线（18）枢转，。还描述了其它实施例。

6. 发明申请

WO2016125137A1 SELF-ORIENTING ENDOVASCULAR DELIVERY SYSTEM 审中-公开
标题翻译：自主性内分泌系统
公开(公告)号：WO2016125137A1
公开(公告)日：2016-08-11
申请号：PCT/IL2016/050049
申请日：2016-01-14
申请人： ENDOSPAN LTD.
发明人： MARMUR, Yaniv , ZIGELBOIM, Or , SHALEV, Alon
IPC分类号： A61F2/966 , A61F2/07
CPC分类号： A61F2/962 , A61F2/07 , A61F2/856 , A61F2/966 , A61F2230/008
摘要： An elongate delivery shaft assembly (30) includes an outer covering shaft (38) and an inner support shaft (40). When the delivery shaft assembly (30) is unconstrained and a stent-graft (20) is removably constrained in a radially-compressed delivery state along a distal end portion (34) of the delivery shaft assembly (30), radially between the outer covering shaft (38) and the inner support shaft (40): (a) the delivery shaft assembly (30) is shaped so as to define a self-orienting portion (50), which (i) is shaped so as to define at least proximal and distal curved portions (52A, 52B), the proximal curved portion (52A) disposed more proximal than the distal curved portion (52B), and (ii) at least one point of inflection (53) on a central longitudinal axis (36) of the delivery shaft assembly (30) longitudinally between the proximal and the distal curved portions (52A, 52B), and (b) respective smallest radii of curvature of the proximal and the distal curved portions (52A, 2B), measured at the central longitudinal axis (36), are each between 2.5 and 12 cm.
摘要翻译：细长输送轴组件（30）包括外覆盖轴（38）和内支撑轴（40）。当输送轴组件（30）不受约束并且支架移植物（20）沿着输送轴组件（30）的远端部分（34）以径向压缩的输送状态可拆卸地约束时，径向地在外覆盖物轴（38）和内支撑轴（40）：（a）输送轴组件（30）成形为限定自取向部分（50），（i）成形为至少限定近端和远端弯曲部分（52A，52B），近端弯曲部分（52A）远离远侧弯曲部分（52B）设置，以及（ii）至少一个拐点（53）在中心纵向轴线（52A，52B）之间纵向布置的输送轴组件（30）的远端弯曲部分（52A，2B）的近似和远端弯曲部分（52A，2B）的最小曲率半径中心纵向轴线（36）各自在2.5和12厘米之间。

7. 发明申请

WO2014141232A1 MULTI-COMPONENT STENT-GRAFT SYSTEM FOR AORTIC DISSECTIONS 审中-公开
标题翻译：用于动态断开的多组分STEG-GRAFT系统
公开(公告)号：WO2014141232A1
公开(公告)日：2014-09-18
申请号：PCT/IL2014/050174
申请日：2014-02-18
申请人： ENDOSPAN LTD.
发明人： SHALEV, Alon , MARMUR, Yaniv
IPC分类号： A61F2/07
CPC分类号： A61F2/856 , A61F2/07 , A61F2/89 , A61F2002/061 , A61F2002/075 , A61F2230/0013 , A61F2230/0069 , A61F2250/0039 , A61F2250/006
摘要： A generally tubular stent-graft has distal and proximal stent-graft ends and includes a generally tubular support element and a covering element. When the stent-graft is unconstrained in a radially-expanded state: the covering and support elements are shaped so as to together define a lateral fenestration having distal and proximal fenestration ends, a perimeter of the distal stent-graft end equals at least 200% of a perimeter of the proximal stent-graft end, and the stent-graft includes a dissection-reinforcement axial portion, which (a) has a proximal dissection-reinforcement end that is disposed no more than 20 mm proximal to the proximal fenestration end, extends along the stent-graft for a distance equal to between 5% and 32% of a greatest perimeter of the stent-graft distally to the distal fenestration end, and (c) has a radial strength that is at least 10% greater than an average radial strength of the entire stent-graft.
摘要翻译：通常管状的支架移植物具有远端和近端的支架移植物端部，并且包括大致管状的支撑元件和覆盖元件。当支架移植物在径向扩张状态下不受约束时：覆盖和支撑元件成形为一起限定具有远端和近端开窗端的侧向开窗，远侧支架移植端的周边等于至少200％近端支架移植端的周边，并且支架移植物包括解剖 - 加强轴向部分，其（a）具有近端解剖加强端，其近端开口端不超过20毫米，沿着支架移植物延伸一段距离等于支架移植物远端远端开窗端的最大周长的5％至32％之间的距离，以及（c）具有至少10％的径向强度整个支架移植物的平均径向强度。

8. 发明申请

WO2013084235A2 BRANCHED STENT-GRAFT SYSTEM 审中-公开
标题翻译：分支式钢筋系统
公开(公告)号：WO2013084235A2
公开(公告)日：2013-06-13
申请号：PCT/IL2012/050506
申请日：2012-12-04
申请人： ENDOSPAN LTD. , BENARY, Raphael , SHALEV, Alon , NAE, Nir Shalom
发明人： BENARY, Raphael , SHALEV, Alon , NAE, Nir Shalom
IPC分类号： A61F2/02
CPC分类号： A61F2/82 , A61F2/07 , A61F2/856 , A61F2/89 , A61F2/915 , A61F2002/061 , A61F2002/067 , A61F2002/075 , A61F2002/91508 , A61F2002/9511 , A61F2220/0075 , A61F2230/0078 , A61F2250/0039 , A61F2250/0098
摘要： An endovascular stent-graft (10) includes a generally tubular hourglass-shaped body (22), which is configured to assume a radially-compressed delivery configuration and a radially-expanded deployment configuration. The hourglass -shaped body (22) includes a flexible stent member (26), which includes a plurality of structural stent elements (28); and a tubular fluid flow guide (24), which includes a fabric (29), and is attached to the structural stent elements (28). The hourglass- shaped body (22) is shaped so as to define a narrow waist portion (32) longitudinally surrounded by and adjacent to wider first and second longitudinal portions (30, 34). The fabric (29) along the waist portion (32) is shaped so as to define at least first and second lateral apertures (36, 38). Other embodiments are also described.
摘要翻译：血管内支架移植物（10）包括通常管状的沙漏形体（22），其构造成呈现径向压缩的递送构型和径向扩张的展开构型。沙漏形体（22）包括柔性支架构件（26），其包括多个结构支架元件（28）; 和包括织物（29）并且附接到结构支架元件（28）的管状流体流动引导件（24）。沙漏形体（22）成形为限定由较宽的第一和第二纵向部分（30,34）纵向包围并相邻的窄腰部分（32）。沿着腰部（32）的织物（29）成形为至少限定第一和第二侧向孔（36,38）。还描述了其它实施例。

9. 发明申请

WO2012104842A3 IMPLANTABLE MEDICAL DEVICES CONSTRUCTED OF SHAPE MEMORY MATERIAL 审中-公开
标题翻译：构造形状记忆材料的可植入医疗器械
公开(公告)号：WO2012104842A3
公开(公告)日：2012-11-22
申请号：PCT/IL2012000060
申请日：2012-02-02
申请人： ENDOSPAN LTD , SHALEV ALON , BERNARY RAPHEL
发明人： SHALEV ALON , BERNARY RAPHEL
IPC分类号： A61F2/95 , A61F2/97
CPC分类号： A61F2/82 , A61F2/07 , A61F2/95 , A61F2/97 , A61F2002/9511
摘要： Medical apparatus (100) is provided for insertion into a mammalian body. The apparatus (100) includes structural stent elements (110), at least a portion of which are shaped so as to define (a) at least one generally circumferential band (112), and (b) a plurality of engagement members (114) that are joined to and extend radially inwardly from the band (112). The apparatus (100) further includes an elongated latch member (118) which is threaded through the engagement members (114), thereby physically latching the engagement members (114). The band (112) and the engagement members (114) are configured such that (a) when the latch member (118) is threaded through and thus physically latches the engagement members (114), the engagement members (114) retain the band (112) in a radially-compressed state, and (b) when the latch member (118) is removed from the engagement members (114), the band (112) assumes a radially-expanded state. Other embodiments are also described.
摘要翻译：提供医疗装置（100）用于插入哺乳动物体内。装置（100）包括结构性支架元件（110），其至少一部分成形为限定（a）至少一个大致圆周的带状物（112），和（b）多个接合构件（114）其从带（112）接合并径向向内延伸。装置（100）还包括细长的闩锁构件（118），其穿过接合构件（114），从而物理地锁定接合构件（114）。带（112）和接合构件（114）构造成使得（a）当闩锁构件（118）穿过并因此物理地闩锁接合构件（114）时，接合构件（114）保持带 112）处于径向压缩状态，和（b）当闩锁构件（118）从接合构件（114）移除时，带（112）呈放射状膨胀状态。还描述了其他实施例。

10. 发明申请

WO2012111006A1 VASCULAR BANDS AND DELIVERY SYSTEMS THEREFOR 审中-公开
标题翻译：其中的血管系统和输送系统
公开(公告)号：WO2012111006A1
公开(公告)日：2012-08-23
申请号：PCT/IL2012/000083
申请日：2012-02-16
申请人： ENDOSPAN LTD. , SHALEV, Alon
发明人： SHALEV, Alon
IPC分类号： A61F2/06
CPC分类号： A61B17/12022 , A61B17/12 , A61F2/07 , A61F2/89 , A61F2002/065
摘要： An extra-luminal ring (1200) includes a structural member (1202), which assumes a first elongate hollow shape (1206) when in a relaxed state; when deformed to a planar state (1208), generally defines a planar shape (1209) having two first sides (1220A, 1220B) parallel to each other, and two second sides (1222A, 1222B) parallel to each other; and when in the relaxed state, is configured such that the two first sides (1220A, 1220B) are generally straight and parallel with each other, and the two second sides (1222A, 1222B) are curved at least partially around a first longitudinal axis (1230) defined by the first elongate hollow shape (1206). The structural member (1202), when in a deformed state, has a second elongate hollow shape (1240), different from the first elongate hollow shape (1206), in which the two second sides (1222A, 1222B) are generally straight and parallel with each other.
摘要翻译：超腔管（1200）包括当处于松弛状态时呈现第一细长中空形状（1206）的结构构件（1202）; 当变形到平面状态（1208）时，通常限定具有彼此平行的两个第一侧面（1220A，1220B）和彼此平行的两个第二侧面（1222A，1222B）的平面形状（1209）并且当处于松弛状态时，被构造为使得两个第一侧（1220A，1220B）大体上彼此平直并且彼此平行，并且两个第二侧（1222A，1222B）至少部分地围绕第一纵向轴线弯曲 1230）由第一细长中空形状（1206）限定。结构构件（1202）当处于变形状态时具有与第一细长中空形状（1206）不同的第二细长中空形状（1240），其中两个第二侧（1222A，1222B）大体上是直的并且平行的与对方

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