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1. 发明申请

WO2008029965A1 SIMULTANEOUS REACTION ASSAY FOR DIFFERENTIALLY DETECTING MULTIMERIC FORM 审中-公开
标题翻译：同步反应测定用于差异检测多种形式
公开(公告)号：WO2008029965A1
公开(公告)日：2008-03-13
申请号：PCT/KR2006/003587
申请日：2006-09-08
申请人： PEOPLEBIO, INC. , AN, Seong Soo Alexander , LIM, Kun Taek , OH, Hyun Jung
发明人： AN, Seong Soo Alexander , LIM, Kun Taek , OH, Hyun Jung
IPC分类号： G01N33/53 , G01N33/68
CPC分类号： G01N33/536 , G01N33/54306
摘要： The present invention relates to a method for differentially detecting a multimeric form from a monomeric form of a multimer-forming polypeptide in a biological sample, comprising the steps of: (a) obtaining the biological sample to be analyzed; (b) preparing an entrapping antibody-affinity molecule conjugate by binding an affinity molecule to the surface of the entrapping antibody, wherein the entrapping antibody recognizes an epitope on the multimer-forming polypeptide; (c) preparing an indicative antibody, wherein an epitope recognized by the indicative antibody is present at a position in the multimer-forming polypeptide to cause a steric hindrance by the entrapping antibody bound to its epitope; (d) contacting the entrapping antibody-affinity molecule conjugate and the indicative antibody to the biological sample in a three dimensional manner; (e) isolating the entrapping antibody-affinity molecule-multimeric form-indicative antibody complex by use of a counterpart affinity molecule; and (f) detecting the formation of the entrapping antibody-affinity molecule-multimeric form-indicative antibody complex.
摘要翻译：本发明涉及用于在生物样品中从单体形式的多聚形成多肽差异检测多聚体形式的方法，包括以下步骤：（a）获得待分析的生物样品; （b）通过将亲和分子结合到所述包埋抗体的表面来制备截留的抗体 - 亲和力分子缀合物，其中所述包埋抗体识别所述多聚体形成多肽上的表位; （c）制备指示性抗体，其中由所述指示性抗体识别的表位存在于所述多聚体形成多肽中的位置，以通过与其表位结合的包载抗体引起空间位阻; （d）以三维方式将捕获的抗体 - 亲和力分子缀合物和指示性抗体与生物样品接触; （e）通过使用对应物亲和分子分离包载的抗体 - 亲和分子 - 多聚体形式指示性抗体复合物; 和（f）检测截留的抗体亲和分子 - 多聚体形式指示性抗体复合物的形成。

2. 发明申请

WO2006088281A1 METHOD FOR DIFFERENTIALLY DETECTING MULTIMERIC FORM FROM MONOMERIC FORM OF MULTIMER-FORMING POLYPEPTIDES 审中-公开
标题翻译：从多元成形多元素的单体形式差异检测多形式的方法
公开(公告)号：WO2006088281A1
公开(公告)日：2006-08-24
申请号：PCT/KR2005/004001
申请日：2005-11-25
申请人： PEOPLEBIO, INC. , AN, Seong Soo Alexander , LIM, Kun Taek , OH, Hyun Jung
发明人： AN, Seong Soo Alexander , LIM, Kun Taek , OH, Hyun Jung
IPC分类号： C12Q1/68
CPC分类号： G01N33/6896
摘要： The present invention relates to a method for differentially detecting a multimeric form from a monomeric form of a multimer-forming polypeptide in a biosample, which comprises the steps of: (a) contacting the biosample to a capturing antibody recognizing an epitope on the multimer-forming polypeptide to capture the monomeric form, multimeric form or monomeric and multimeric forms; (b) contacting the monomeric form, multimeric form or monomeric and multimeric forms captured to a detecting antibody recognizing an epitope identical to or overlapped with the epitope of step (a); and (c) detecting the formation of a multimeric form-detection antibody complex.
摘要翻译：本发明涉及在生物样品中从单体形式的多聚形成多肽差异检测多聚体形式的方法，其包括以下步骤：（a）使生物样品与识别多聚体形成多肽的表位的捕获抗体接触，形成多肽以捕获单体形式，多聚体形式或单体和多聚体形式; （b）将捕获的单体形式，多聚体形式或单体和多聚体形式与识别与步骤（a）的表位相同或重叠的表位的检测抗体接触; 和（c）检测多聚体形式检测抗体复合物的形成。

3. 发明申请

WO2010058980A2 SINGLE CRYSTAL GROWING APPARATUS 审中-公开
标题翻译：单晶生长装置
公开(公告)号：WO2010058980A2
公开(公告)日：2010-05-27
申请号：PCT/KR2009/006830
申请日：2009-11-20
申请人： SILTRON INC. , LEE, Sang Hun , CHOI, ll Soo , OH, Hyun Jung , JEONG, Seung , MOON, Ji Hun , KIM, Do Yeon
发明人： LEE, Sang Hun , CHOI, ll Soo , OH, Hyun Jung , JEONG, Seung , MOON, Ji Hun , KIM, Do Yeon
IPC分类号： C30B15/14 , C30B15/30
CPC分类号： C30B15/14 , C30B15/16 , C30B29/06
摘要： Embodiments provide a single crystal growing apparatus. The single crystal growing apparatus may include a chamber, a crucible, a heater, and heat supplying means. The crucible may be provided in the chamber to hold silicon melt. The heater may be provided in the chamber to heat the crucible. The heat supplying means may supply heat to a crystal at a necking portion during single crystal growth.
摘要翻译：实施例提供单晶生长装置。单晶生长装置可以包括室，坩埚，加热器和供热装置。坩埚可以设置在室中以保持硅熔体。加热器可以设置在室中以加热坩埚。在单晶生长期间，供热装置可在颈缩部分向晶体供应热量。

4. 发明申请

WO2009011500A2 METHODS FOR DECREASING FALSE SIGNALS IN IMMUNOASSAY TO DETECT A MULTIMERIC FORM FROM A MONOMERIC FORM OF MULTIMER-FORMING POLYPEPTIDES 审中-公开
标题翻译：减少免疫检测中的错误信号以从多聚形式的多肽的单体形式检测多形式的方法
公开(公告)号：WO2009011500A2
公开(公告)日：2009-01-22
申请号：PCT/KR2008003532
申请日：2008-06-20
申请人： PEOPLEBIO INC , OH HYUN-JUNG , LIM KUN-TAEK
发明人： OH HYUN-JUNG , LIM KUN-TAEK
IPC分类号： G01N33/53
CPC分类号： G01N33/54393
摘要： The present invention provides a method for decreasing false signals in immunoassay to detect a multimeric form of multimer-forming polypeptides with an antibody, which comprises the step of contacting a biosample with NADPH (Nicotiamide adenine dinucleotide phosphate (reduced form)) and a method for differentially detecting a multimeric form from a monomeric form of multimer- forming polypeptides in a biosample. The present invention may differentially detect a multimeric form from a monomeric form of multimer-forming polypeptides easily in a high-throughput manner. The present invention may detect a multimeric form of multimer-forming polypeptides associated with various diseases in a high-throughput manner and particularly is very efficient to detect a scrapie form of prion.
摘要翻译：本发明提供了在免疫测定中减少假信号以用抗体检测多聚体形式多肽的方法，该方法包括使生物样品与NADPH（烟酰胺腺嘌呤二核苷酸磷酸（还原形式））接触的步骤和用于从生物样品中单体形式的多聚体形成多肽差异检测多聚体形式。本发明可以容易地以高通量方式差异检测来自多聚体形成多肽的单体形式的多聚体形式。本发明可以以高通量方式检测与多种疾病相关的多聚体形成多肽的多聚体形式，并且特别是对于检测瘙痒症形式的朊病毒是非常有效的。

5. 发明申请

WO2005038045A1 METHOD AND KIT FOR MEASURING THE ACTIVITY OF FACTOR XIII 审中-公开
标题翻译：用于测量因子XIII的活性的方法和工具箱
公开(公告)号：WO2005038045A1
公开(公告)日：2005-04-28
申请号：PCT/KR2003/002174
申请日：2003-10-17
申请人： PEOPLEBIO, INC. , AN, Seong Soo Alexander , SUH, In Bum , LIM, Kun Taek , OH, Hyun Jung
发明人： AN, Seong Soo Alexander , SUH, In Bum , LIM, Kun Taek , OH, Hyun Jung
IPC分类号： C12Q1/28
CPC分类号： C12Q1/28 , G01N33/86 , G01N2333/745
摘要： The present invention relates to a method and a kit for measuring the activity of Factor XIII, more particularly a method and a kit for measuring the activity of Factor XIII in a sample so that Factor XIII may be quantitated in more reliable and convenient manner.
摘要翻译：本发明涉及用于测定因子XIII的活性的方法和试剂盒，更具体地说，涉及一种用于测量样品中因子XIII的活性的方法和试剂盒，以使得因子XIII可以以更可靠和方便的方式进行定量。

6. 发明申请

WO2011083898A1 INSULATION DEVICE OF SINGLE CRYSTAL GROWTH DEVICE AND SINGLE CRYSTAL GROWTH DEVICE INCLUDING THE SAME 审中-公开
标题翻译：单晶生长装置的绝缘装置和包括其的单晶生长装置
公开(公告)号：WO2011083898A1
公开(公告)日：2011-07-14
申请号：PCT/KR2010/004775
申请日：2010-07-21
申请人： LG SILTRON INC. , LEE, Sang-Hoon , OH, Hyun-Jung , CHOI, Il-Soo
发明人： LEE, Sang-Hoon , OH, Hyun-Jung , CHOI, Il-Soo
IPC分类号： C30B15/00 , C30B35/00 , C30B29/06 , H01L21/02
CPC分类号： C30B35/00 , C30B11/003 , C30B15/14 , Y10T117/1068
摘要： Provides are an insulation device of a single crystal growth device and a single crystal growth device including the same. The insulation device is installed inside a chamber of the single crystal growth device and the insulation device includes a plurality of insulation blocks that are spaced by a first distance.
摘要翻译：提供单晶生长装置的绝缘装置和包括其的单晶生长装置。绝缘装置安装在单晶生长装置的室内，并且绝缘装置包括间隔第一距离的多个绝缘块。

7. 发明申请

WO2010058980A3 SINGLE CRYSTAL GROWING APPARATUS 审中-公开
标题翻译：单晶生长设备
公开(公告)号：WO2010058980A3
公开(公告)日：2010-08-19
申请号：PCT/KR2009006830
申请日：2009-11-20
申请人： SILTRON INC , LEE SANG HUN , CHOI LL SOO , OH HYUN JUNG , JEONG SEUNG , MOON JI HUN , KIM DO YEON
发明人： LEE SANG HUN , CHOI LL SOO , OH HYUN JUNG , JEONG SEUNG , MOON JI HUN , KIM DO YEON
IPC分类号： C30B15/14 , C30B15/30
CPC分类号： C30B15/14 , C30B15/16 , C30B29/06
摘要： Embodiments provide a single crystal growing apparatus. The single crystal growing apparatus may include a chamber, a crucible, a heater, and heat supplying means. The crucible may be provided in the chamber to hold silicon melt. The heater may be provided in the chamber to heat the crucible. The heat supplying means may supply heat to a crystal at a necking portion during single crystal growth.
摘要翻译：实施例提供了一种单晶生长设备。单晶生长设备可以包括腔室，坩埚，加热器和供热装置。坩埚可以设置在室中以保持硅熔体。加热器可以设置在室中以加热坩埚。供热装置可以在单晶生长期间向颈缩部分处的晶体供热。

8. 发明申请

WO2009011500A3 METHODS FOR DECREASING FALSE SIGNALS IN IMMUNOASSAY TO DETECT A MULTIMERIC FORM FROM A MONOMERIC FORM OF MULTIMER-FORMING POLYPEPTIDES 审中-公开
公开(公告)号：WO2009011500A3
公开(公告)日：2009-01-22
申请号：PCT/KR2008/003532
申请日：2008-06-20
申请人： PEOPLEBIO, INC. , OH, Hyun-Jung , LIM, Kun-Taek
发明人： OH, Hyun-Jung , LIM, Kun-Taek
IPC分类号： G01N33/53
摘要： The present invention provides a method for decreasing false signals in immunoassay to detect a multimeric form of multimer-forming polypeptides with an antibody, which comprises the step of contacting a biosample with NADPH (Nicotiamide adenine dinucleotide phosphate (reduced form)) and a method for differentially detecting a multimeric form from a monomeric form of multimer- forming polypeptides in a biosample. The present invention may differentially detect a multimeric form from a monomeric form of multimer-forming polypeptides easily in a high-throughput manner. The present invention may detect a multimeric form of multimer-forming polypeptides associated with various diseases in a high-throughput manner and particularly is very efficient to detect a scrapie form of prion.

9. 发明申请

WO2007123345A1 METHOD FOR DIFFERENTIALLY DETECTING MULTIMERIC FORM FROM MONOMERIC FORM OF MULTIMER-FORMING POLYPEPTIDES THROUGH THREE-DIMENSIONAL INTERACTIONS 审中-公开
标题翻译：通过三维相互作用从多元形成多聚体单体形式中分别检测多形式的方法
公开(公告)号：WO2007123345A1
公开(公告)日：2007-11-01
申请号：PCT/KR2007/001947
申请日：2007-04-20
申请人： PEOPLEBIO, INC. , AN, Seong, Soo, Alexander , LIM, Kun Taek , OH, Hyun Jung
发明人： AN, Seong, Soo, Alexander , LIM, Kun Taek , OH, Hyun Jung
IPC分类号： G01N33/49
CPC分类号： G01N33/6854 , G01N33/54306
摘要： The present invention relates to a method for differentially detecting a multimeric form from a monomeric form of a multimer-forming polypeptide in a biosample, which comprises the steps of: (a) preparing a carrier-capturing antibody conjugate by binding a capturing antibody to the surface of a solid phase carrier in a three dimensional manner, wherein the capturing antibody is capable of recognizing an epitope on the multimer-forming polypeptide; (b) preparing a detection antibody, wherein an epitope recognized by the detection antibody is present at a position in the multimer-forming polypeptide to cause a steric hindrance by the capturing antibody bound to its epitope to prevent the binding of the detection antibody to the multimer-forming polypeptide; (c) contacting simultaneously the carrier-capturing antibody conjugate and the detection antibody to the biosample; and (d) detecting the formation of a carrier-capturing antibody-multimeric form-detection antibody complex.
摘要翻译：本发明涉及用于在生物样品中从单体形式的多聚形成多肽差异检测多聚体形式的方法，其包括以下步骤：（a）通过将捕获抗体结合到制备载体捕获抗体结合体三维方式的固相载体的表面，其中所述捕获抗体能够识别所述多聚体形成多肽上的表位; （b）制备检测抗体，其中由所述检测抗体识别的表位存在于所述多聚形成多肽中的位置，以通过与其表位结合的捕获抗体引起空间位阻，以防止检测抗体与多聚体形成多肽; （c）同时将载体捕获抗体缀合物和检测抗体与生物样品接触; 和（d）检测载体捕获抗体 - 多聚体形式检测抗体复合物的形成。

10. 发明申请

WO2012121573A3 AUGMENTATIVE AND ALTERNATIVE COMMUNICATION DEVICE FOR DISABLED PERSON 审中-公开
标题翻译：禁用人员的备选和替代通信设备
公开(公告)号：WO2012121573A3
公开(公告)日：2012-12-27
申请号：PCT/KR2012001772
申请日：2012-03-12
申请人： KOREA NAZARENE UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION , YOOK JU HYE , OH HYUN JUNG , LEE PYOUNG HO , GO HA NULE , BAE JONG HOON
发明人： YOOK JU HYE , OH HYUN JUNG , LEE PYOUNG HO , GO HA NULE , BAE JONG HOON
IPC分类号： G09B21/04 , G09B5/00
CPC分类号： G09B19/00 , G09B21/009 , G09B21/04
摘要： The present invention relates to an augmentative and alternative communication device for a disabled person, and more specifically, to an augmentative and alternative communication device for a disabled person, wherein a disabled person while having the ability to view and perceive pictures to some extent is able to express personal intentions. The augmentative and alternative communication device for a disabled person according to the present invention comprises: a plate-shaped body in which an indicator connection bar is protruded from a frontal center thereof; an intention-expressing plate which is attached to the front side of said body, and in which a plurality of symbols are radially attached thereto; an indicator which is rotatably connected to said indicator connection bar, and indicates a corresponding symbol according to the instructions of a user; and a controller which is installed on the lower part of said body, and controls the operation of said indicator by receiving an input signal of the user.
摘要翻译：本发明涉及一种用于残疾人的增强和替代通信装置，更具体地，涉及一种用于残疾人的增强和替代通信装置，其中残疾人在具有在某种程度上观看和感知图像的能力是可以的表达个人意图。根据本发明的用于残疾人的增强和替代通信装置包括：板状体，其中指示器连接杆从其正面中心突出; 意图表示板，其附接到所述主体的前侧，并且多个符号径向地附接到所述主体; 指示器，其可旋转地连接到所述指示器连接杆，并且根据用户的指令指示相应的符号; 以及安装在所述主体的下部的控制器，并且通过接收用户的输入信号来控制所述指示器的操作。

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