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1. 发明申请

WO2012122285A1 CAPSULAR MEMBRANE IMPLANTS TO INCREASE ACCOMMODATIVE AMPLITUDE 审中-公开
标题翻译：囊体膜植入物增加舒张功能
公开(公告)号：WO2012122285A1
公开(公告)日：2012-09-13
申请号：PCT/US2012/028095
申请日：2012-03-07
申请人： ABBOTT MEDICAL OPTICS INC. , BRADY, Daniel, G. , BOR, Zsolt , GERAGHTY, Edward , BASINGER, Brooke , REISIN, Carina, R. , CALI, Douglas
发明人： BRADY, Daniel, G. , BOR, Zsolt , GERAGHTY, Edward , BASINGER, Brooke , REISIN, Carina, R. , CALI, Douglas
IPC分类号： A61F2/14
CPC分类号： A61F2/14 , A61F2/1624 , A61F9/00736 , A61F9/008 , A61F9/00838 , A61F2002/1681 , A61F2009/0087 , A61F2009/00889 , A61F2009/00895 , F04C2270/0421
摘要： A support is coupled to the lens capsule to increase accommodation. The support may be adjustable, such that patient refraction and accommodation can be adjusted following surgery. The support may comprise rigidity sufficient to decrease radial movement of the intermediate portion of the lens capsule. The support can be placed on the intermediate portion to decrease radial movement of the intermediate portion of the lens capsule and increase radial stretching of an outer portion of the lens capsule extending between the zonules and the intermediate portion coupled to the support, such that the amount of accommodation of the eye is increased. The support may comprise a biocompatible material capable of stable coupling to the lens capsule following implantation, such that the far vision refraction and accommodation of the eye can be stable following surgery.
摘要翻译：支撑件联接到镜片胶囊以增加调节。支撑件可以是可调节的，使得在手术后可以调整患者的折射和容纳。支撑件可以包括足以减小透镜胶囊的中间部分的径向移动的刚度。可以将支撑件放置在中间部分上以减小透镜胶囊的中间部分的径向移动，并且增加透镜胶囊的在部分与连接到支撑件的中间部分之间延伸的外部部分的径向拉伸，使得量眼睛的适应性增加。支撑体可以包括能够在植入之后稳定地耦合到晶状体囊的生物相容性材料，使得眼睛的远视力折射和适应在手术后可以是稳定的。

2. 发明申请

WO2012122281A3 CAPSULAR MEMBRANE TREATMENTS TO INCREASE ACCOMMODATIVE AMPLITUDE 审中-公开
标题翻译： CAPSULAR膜治疗增加舒张功能
公开(公告)号：WO2012122281A3
公开(公告)日：2012-11-15
申请号：PCT/US2012028090
申请日：2012-03-07
申请人： ABBOTT MEDICAL OPTICS INC , BOR ZSOLT , BRADY DANIEL G , GERAGHTY EDWARD , REISIN CARINA R , CALI DOUGLAS
发明人： BOR ZSOLT , BRADY DANIEL G , GERAGHTY EDWARD , REISIN CARINA R , CALI DOUGLAS
IPC分类号： A61F9/007
CPC分类号： A61F9/013 , A61F2/16 , A61F9/00 , A61F9/0008 , A61F9/0017 , A61F9/007 , A61F9/00736 , A61F9/0079 , A61F9/008 , A61F9/00838 , A61F2009/0087 , A61F2009/00889 , A61F2009/00895
摘要： Methods and apparatus treat the lens capsule so as to increase accommodation of the eye. The treatment of the lens capsule may comprise treating a portion of the lens capsule so as to stiffen the treated portion and improve accommodation of the eye. The intermediate portion of the lens capsule may located between an optically used central portion of the lens capsule and a peripheral portion of the lens capsule connected to zonules of the eye. The stiffened intermediate portion of the lens capsule can improve coupling of the peripheral portion of the lens capsule to the central portion of the lens capsule, such that an amount of accommodation of the optically used central portion of the lens is increased. As the force of the lens capsule to a lens disposed within the lens capsule is increased, the lens may comprise the natural lens of the eye or an artificial lens such as an accommodative IOL. The treatment of the eye to stiffen the intermediate portion may comprise application of one or more of an energy or a substance to the intermediate portion.
摘要翻译：方法和装置处理晶状体囊以增加眼睛的适应性。透镜胶囊的治疗可以包括处理透镜胶囊的一部分，以便加强经处理的部分并改善眼睛的适应性。透镜胶囊的中间部分可以位于透镜胶囊的光学使用的中心部分和与眼睛的小区连接的透镜胶囊的周边部分之间。透镜胶囊的加强的中间部分可以改善透镜胶囊的周边部分与透镜胶囊的中心部分的联接，使得透镜的光学中心部分的调节量增加。当透镜胶囊对设置在透镜胶囊内的透镜的力增加时，透镜可以包括眼睛的天然晶状体或诸如调节性IOL的人造镜片。治疗眼睛以加强中间部分可以包括向中间部分施加一种或多种能量或物质。

3. 发明申请

WO2010135685A1 OPHTHALMIC LENSES WITH ENHANCED SURFACE AND METHODS OF FABRICATION THEREOF 审中-公开
标题翻译：具有增强表面的眼镜及其制造方法
公开(公告)号：WO2010135685A1
公开(公告)日：2010-11-25
申请号：PCT/US2010/035832
申请日：2010-05-21
申请人： ABBOTT MEDICAL OPTICS INC. , BUMBALOUGH, Timothy, R. , GERAGHTY, Edward , BRADY, Daniel, G.
发明人： BUMBALOUGH, Timothy, R. , GERAGHTY, Edward , BRADY, Daniel, G.
IPC分类号： A61F2/16
CPC分类号： A61F2/1613 , A61F2/1616 , A61F2/1618 , A61F2/1648 , A61F2002/1681 , A61F2002/1699 , A61F2210/0076 , A61F2240/001 , A61F2250/0053 , B29D11/023
摘要： An ophthalmic lens (100) for providing enhanced vision includes a finished optic (105) comprising a base optic (115) and a shell (135). The base optic has an anterior surface (120) and an opposing posterior surface (125), at least one of the surfaces having a first value of a surface quality parameter. The shell includes a membrane (140, 150) including an inner surface and an outer surface, the inner surface covering one or more of the surfaces of the base optic. The outer surface has a second value of the surface quality parameter, wherein the second value is greater than the first value.
摘要翻译：用于提供增强视觉的眼用透镜（100）包括包括基底光学元件（115）和外壳（135）的成品光学元件（105）。基部光学元件具有前表面（120）和相对的后表面（125），至少一个表面具有表面质量参数的第一值。壳体包括包括内表面和外表面的膜（140,150），内表面覆盖基底光学元件的一个或多个表面。外表面具有表面质量参数的第二值，其中第二值大于第一值。

4. 发明申请

WO2009120910A1 SYSTEMS FOR OCULAR MEASUREMENTS 审中-公开
标题翻译： OCULAR测量系统
公开(公告)号：WO2009120910A1
公开(公告)日：2009-10-01
申请号：PCT/US2009/038469
申请日：2009-03-26
申请人： ABBOTT MEDICAL OPTICS INC. , DEACON, Jim , GERAGHTY, Edward
发明人： DEACON, Jim , GERAGHTY, Edward
IPC分类号： A61B3/10 , A61B3/117 , A61F9/00 , G01B5/12
CPC分类号： A61B3/10 , A61B3/1005 , A61B3/117 , A61B5/1076 , A61F2/1694 , G01B3/563
摘要： A system for measuring the size of a capsular bag of an eye of a subject includes a size indicator (30) and a sizing gauge (70,102,202,302). The size indicator is configured for insertion into a capsular bag and includes a peripheral portion (31) and a pair of arms (32,33). The peripheral portion is configured to engage the capsular bag. Each of the arms has a proximal end (39) and a distal end (34,35), the arms being joined to one another at the proximal ends (39). The peripheral portion is joined to the distal ends of the arms. The arms form an angle that depends on a size of the capsular bag into which the size indicator is placed. The sizing gauge has a body having a front surface, along with first and second features (74-76) disposed along or behind the front surface. The features are configured to correspond to an angle that is within a predetermined range of angles of the arms of the size indicator when the size indicator is placed within a capsular bag.
摘要翻译：用于测量受试者眼睛的囊袋的尺寸的系统包括尺寸指示器（30）和尺寸计（70,102,202,302）。尺寸指示器构造成用于插入囊袋中并且包括周边部分（31）和一对臂（32,33）。周边部分构造成接合囊袋。每个臂具有近端（39）和远端（34,35），臂在近端（39）处彼此连接。周边部分连接到臂的远端。手臂形成取决于尺寸指示器放置在其中的囊袋的尺寸的角度。尺寸表具有具有前表面的主体以及沿着前表面或之后设置的第一和第二特征（74-76）。特征被配置成对应于当尺寸指示器放置在囊袋内时尺寸指示器的臂的预定角度范围内的角度。

5. 发明申请

WO2004089252A3 ASPHERIC INTRAOCULAR LENS 审中-公开
标题翻译：腹腔镜
公开(公告)号：WO2004089252A3
公开(公告)日：2004-12-09
申请号：PCT/US2004009737
申请日：2004-03-31
申请人： BAUSCH & LOMB , GERAGHTY EDWARD , HOFFMAN M LAURENT , NGUYEN TUAN ANH
发明人： GERAGHTY EDWARD , HOFFMAN M LAURENT , NGUYEN TUAN ANH
IPC分类号： A61F2/16 , G02C7/02
CPC分类号： A61F2/1605 , A61F2/1613
摘要： An intraocular lens (24) for placement into the anterior chamber of a human eye having an optic (22) with a central axis (33), an anterior surface (27) and a posterior surface (26). At least one of the surfaces is a rotationally symmetric shaped surface with a center of curvature on the central axis and an 10 aspheric portion (35) formed in a peripheral area of the spherically shaped surface. An attachment mechanism fastens the intraocular lens between the iris and the cornea.
摘要翻译：一种用于放置在具有中心轴线（33），前表面（27）和后表面（26）的光学元件（22）的人眼前房中的眼内透镜（24）。至少一个表面是在中心轴线上具有曲率中心的旋转对称形状的表面和形成在球形表面的周边区域中的10个非球面部分（35）。附着机构将眼内透镜固定在虹膜和角膜之间。

6. 发明申请

WO2004089252A2 ASPHERIC INTRAOCULAR LENS 审中-公开
标题翻译：腹腔镜
公开(公告)号：WO2004089252A2
公开(公告)日：2004-10-21
申请号：PCT/US2004/009737
申请日：2004-03-31
申请人： BAUSCH & LOMB INCORPORATED , GERAGHTY, Edward , HOFFMAN, M, Laurent , NGUYEN, Tuan, Anh
发明人： GERAGHTY, Edward , HOFFMAN, M, Laurent , NGUYEN, Tuan, Anh
IPC分类号： A61F2/16
CPC分类号： A61F2/1605 , A61F2/1613
摘要： An intraocular lens for placement into the anterior chamber of a human eye having an optic with a central axis, an anterior surface and a posterior surface. At least one of the surfaces is a rotationally symmetric shaped surface with a center of curvature on the central axis and an 10 aspheric portion formed in a peripheral area of the spherically shaped surface. An attachment mechanism fastens the intraocular lens between the iris and the cornea.
摘要翻译：一种眼内透镜，用于放置在具有中心轴线，前表面和后表面的光学元件的人眼前房中。至少一个表面是在中心轴线上具有曲率中心的旋转对称形状的表面和形成在球形表面的周边区域中的10个非球面部分。附着机构将眼内透镜固定在虹膜和角膜之间。

7. 发明申请

WO2013166308A1 INTRAOCULAR LENS WITH SHAPE CHANGING CAPABILTIY TO PROVIDE ENHANCED ACCOMODATION AND VISUAL ACUITY 审中-公开
标题翻译：具有形状改变能力的内窥镜提供增强的摄影和视觉功能
公开(公告)号：WO2013166308A1
公开(公告)日：2013-11-07
申请号：PCT/US2013/039302
申请日：2013-05-02
申请人： ABBOTT MEDICAL OPTICS INC. , BRADY, Daniel, G. , ZHAO, Huawei , GERAGHTY, Edward , CATLIN, Scott, J.
发明人： BRADY, Daniel, G. , ZHAO, Huawei , GERAGHTY, Edward , CATLIN, Scott, J.
IPC分类号： A61F2/16
CPC分类号： A61F2/1618 , A61F2/1624 , A61F2/1635 , A61F2002/1681 , A61F2002/1682 , A61F2002/1689 , A61F2250/0018
摘要： An intraocular lens for providing a range of accommodative vision, an extended depth of focus, or enhanced performance through the asymmetric transfer of ocular forces to the lens. The intraocular lens contains an optic and a haptic. The shape and/or material of the haptic results in the transmission of ocular forces to particular regions in the optic. Greater forces applied to particular regions result in deformation of that region and increased power.
摘要翻译：一种眼内透镜，用于通过对眼镜的不对称转移提供一定范围的调节视力，扩大的焦点深度或增强的性能。眼内透镜包含视神经和触觉。触觉的形状和/或材料导致眼力传递到光学元件中的特定区域。施加到特定区域的更大的力导致该区域的变形并增加功率。

8. 发明申请

WO2008083283A3 MULTIFOCAL ACCOMMODATING INTRAOCULAR LENS 审中-公开
标题翻译：多功能摄影镜片
公开(公告)号：WO2008083283A3
公开(公告)日：2011-10-13
申请号：PCT/US2007089060
申请日：2007-12-28
申请人： ADVANCED MEDICAL OPTICS INC , GERAGHTY EDWARD , BRADY DANIEL G , BUMBALOUGH TIMOTHY R , CALI DOUGLAS S
发明人： GERAGHTY EDWARD , BRADY DANIEL G , BUMBALOUGH TIMOTHY R , CALI DOUGLAS S
IPC分类号： A61F2/16
CPC分类号： A61F2/1613 , A61F2/1618 , A61F2/1624 , A61F2/1635 , A61F2/164 , A61F2/1645 , A61F2/1654 , A61F2002/1681 , A61F2250/0014
摘要： An intraocular lens for providing accommodative visions to a subject includes an adjustable optic and a haptic that is operably coupled to the optic. The adjustable optic comprises an optical axis, a central zone disposed about the optical axis, and an annular zone surrounding the central zone. The optic may also comprise additional annular zones disposed about the central zone and the first annular zone. The haptic comprises a transparent portion protruding into the adjustable optic. The intraocular lens has a disaccommodative configuration in which the central zone has a base optical power and an accommodative configuration in which the central zone has an add optical power that is at least about 1 Diopter greater than the base optical power, preferably at least about 2 Diopters greater than the base optical power. In some embodiments, the add optical power is at least 3 Diopters, or even 4 Diopters, greater than the base optical power. The central zone and the annular zone have different optical powers when the adjustable intraocular lens is in the accommodative configuration and/or when the adjustable intraocular lens is in the disaccommodative configuration.
摘要翻译：用于向受试者提供调节视力的眼内透镜包括可操作地连接到光学元件的可调光学元件和触觉件。可调节光学元件包括光轴，围绕光轴设置的中心区域和围绕中心区域的环形区域。光学元件还可以包括围绕中心区域和第一环形区域设置的附加环形区域。触觉包括突出到可调节光学元件中的透明部分。眼内透镜具有不利的配置，其中中心区域具有基本光焦度和调节结构，其中中心区域具有比基本光功率大至少约1屈光度的添加光焦度，优选至少约2 屈光度大于基础光功率。在一些实施例中，添加光功率大于基本光功率的至少3屈光度，或甚至4屈光度。当可调节眼内透镜处于调节构型时和/或当可调节眼内透镜处于不利配置时，中心区域和环形区域具有不同的光焦度。

9. 发明申请

WO2009088461A3 5-NITROVANIIILIN AS A CALIBRANT FOR CALIBRATING THE DRIFT TIME FOR AN ION MOBILITY SPECTROMETER 审中-公开
公开(公告)号：WO2009088461A3
公开(公告)日：2009-07-16
申请号：PCT/US2008/014086
申请日：2008-12-29
申请人： IMPLANT SCIENCES CORPORATION , GERAGHTY, Edward , KEKUKH, Vladimer , BUNKER, Stephen, N.
发明人： GERAGHTY, Edward , KEKUKH, Vladimer , BUNKER, Stephen, N.
IPC分类号： G01N27/64 , G01N33/00
摘要： An explosive and narcotics detection system using an ion mobility spectrometer detects the presence of vapor or trace particles of target chemicals. The calibration of the spectrometer depends in part on the stability of a calibrant chemical that may be periodically injected together with sample gas into the ionization region of the spectrometer. The calibrant chemical produces a signal with a drift time that is known relative to target chemicals and may be used to calibrate the expected target chemical drift times. A new solid calibrant chemical, 5-nitrovanillin, is disclosed for this purpose. During calibration the calibrant is heated to produce a calibrant gas.

10. 发明申请

WO2008134322A1 ANGLE INDICATOR FOR CAPSULAR BAG SIZE MEASUREMENT 审中-公开
标题翻译：角度尺寸测量角度指示器
公开(公告)号：WO2008134322A1
公开(公告)日：2008-11-06
申请号：PCT/US2008/061180
申请日：2008-04-22
申请人： ADVANCED MEDICAL OPTICS, INC. , DEACON, Jim , GERAGHTY, Edward , ZALESKI, Edward
发明人： DEACON, Jim , GERAGHTY, Edward , ZALESKI, Edward
IPC分类号： A61B3/10 , A61B3/117 , A61F9/00 , G01B5/12
CPC分类号： A61B3/1005 , A61B3/117 , A61B5/1076 , A61F2/14 , A61F2250/0059 , G01B3/563
摘要： Implantation of an accommodating intraocular lens in an eye may require the accurate measurement of the size, circumference, or diameter of the capsular bag of the eye. After the natural crystalline lens has been surgically removed, a flexible ring (30) may be temporarily or permanently inserted into the capsular bag for measuring the circumference of the capsular bag. The ring is generally compressible to fit through a surgical incision, then expands to fill the capsular bag along an equatorial region. The ring has a central component (32, 33) that changes shape as the ring is compressed. The shape change is generally correlated to the size of the capsular bag and may be measured visually or with a camera through the cornea, the measurement being generally independent of corneal magnification.
摘要翻译：在眼睛中植入适应性眼内透镜可能需要准确测量眼睛囊袋的尺寸，周长或直径。在通过外科手术取出天然晶状体之后，可以将柔性环（30）暂时或永久地插入囊袋中，以测量囊袋的周长。环通常可压缩以通过手术切口装配，然后膨胀以沿着赤道区域填充囊袋。该环具有随着环被压缩而改变形状的中心部件（32,33）。形状变化通常与囊袋的尺寸相关，并且可以通过眼睛或通过角膜的相机进行测量，该测量通常与角膜放大倍数无关。

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