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1. 发明申请

WO2010151691A2 ACCOMMODATING INTRAOCULAR LENSES 审中-公开
标题翻译：适应眼内镜片
公开(公告)号：WO2010151691A2
公开(公告)日：2010-12-29
申请号：PCT/US2010/039858
申请日：2010-06-24
申请人： ABBOTT MEDICAL OPTICS INC. , BUMBALOUGH, Timothy, R. , JAIN, Rakhi , CATLIN, Scott, J. , YORITA, Tamara, J.
发明人： BUMBALOUGH, Timothy, R. , JAIN, Rakhi , CATLIN, Scott, J. , YORITA, Tamara, J.
IPC分类号： A61F2/16
CPC分类号： A61F2/1613 , A61F2/1624 , A61F2/1635 , A61F2/1648 , A61F2/1694 , A61F2002/1681 , A61F2002/1682 , A61F2002/16901
摘要： An intraocular lens is disclosed, with an optic that changes shape in response to a deforming force exerted by the zonules of the eye. A haptic supports the optic around its equator and couples the optic to the capsular bag of the eye. Certain haptic features improve the accommodative performance of the haptic, such that compressive/tensile forces may be more efficiently transferred from the haptic to optic. Furthermore, certain aspects also provide enhanced bag-sizing capability so that the IOL better fits within the capsular bag.
摘要翻译：公开了一种人工晶状体，其具有响应于眼睛小带所施加的变形力而改变形状的光学部件。触觉支持光学装置在赤道附近，并将光学部件连接到眼睛的囊袋。某些触觉特征改善了触觉的调节性能，使得压缩/拉伸力可以更有效地从触觉传递到视觉。此外，某些方面还提供了增强的袋尺寸能力，使得IOL更好地适合囊袋内。

2. 发明申请

WO2008083283A3 MULTIFOCAL ACCOMMODATING INTRAOCULAR LENS 审中-公开
标题翻译：多功能摄影镜片
公开(公告)号：WO2008083283A3
公开(公告)日：2011-10-13
申请号：PCT/US2007089060
申请日：2007-12-28
申请人： ADVANCED MEDICAL OPTICS INC , GERAGHTY EDWARD , BRADY DANIEL G , BUMBALOUGH TIMOTHY R , CALI DOUGLAS S
发明人： GERAGHTY EDWARD , BRADY DANIEL G , BUMBALOUGH TIMOTHY R , CALI DOUGLAS S
IPC分类号： A61F2/16
CPC分类号： A61F2/1613 , A61F2/1618 , A61F2/1624 , A61F2/1635 , A61F2/164 , A61F2/1645 , A61F2/1654 , A61F2002/1681 , A61F2250/0014
摘要： An intraocular lens for providing accommodative visions to a subject includes an adjustable optic and a haptic that is operably coupled to the optic. The adjustable optic comprises an optical axis, a central zone disposed about the optical axis, and an annular zone surrounding the central zone. The optic may also comprise additional annular zones disposed about the central zone and the first annular zone. The haptic comprises a transparent portion protruding into the adjustable optic. The intraocular lens has a disaccommodative configuration in which the central zone has a base optical power and an accommodative configuration in which the central zone has an add optical power that is at least about 1 Diopter greater than the base optical power, preferably at least about 2 Diopters greater than the base optical power. In some embodiments, the add optical power is at least 3 Diopters, or even 4 Diopters, greater than the base optical power. The central zone and the annular zone have different optical powers when the adjustable intraocular lens is in the accommodative configuration and/or when the adjustable intraocular lens is in the disaccommodative configuration.
摘要翻译：用于向受试者提供调节视力的眼内透镜包括可操作地连接到光学元件的可调光学元件和触觉件。可调节光学元件包括光轴，围绕光轴设置的中心区域和围绕中心区域的环形区域。光学元件还可以包括围绕中心区域和第一环形区域设置的附加环形区域。触觉包括突出到可调节光学元件中的透明部分。眼内透镜具有不利的配置，其中中心区域具有基本光焦度和调节结构，其中中心区域具有比基本光功率大至少约1屈光度的添加光焦度，优选至少约2 屈光度大于基础光功率。在一些实施例中，添加光功率大于基本光功率的至少3屈光度，或甚至4屈光度。当可调节眼内透镜处于调节构型时和/或当可调节眼内透镜处于不利配置时，中心区域和环形区域具有不同的光焦度。

3. 发明申请

WO2010151693A2 ACCOMMODATING INTRAOCULAR LENSES 审中-公开
标题翻译：住院镜片
公开(公告)号：WO2010151693A2
公开(公告)日：2010-12-29
申请号：PCT/US2010/039860
申请日：2010-06-24
申请人： ABBOTT MEDICAL OPTICS INC. , BUMBALOUGH, Timothy, R.
发明人： BUMBALOUGH, Timothy, R.
IPC分类号： A61F2/16
CPC分类号： A61F2/1613 , A61F2/1624 , A61F2/1635 , A61F2/1648 , A61F2/1694 , A61F2002/1681 , A61F2002/1682 , A61F2002/16901
摘要： An intraocular lens is disclosed, with an optic that changes shape in response to a deforming force exerted by the zonules of the eye. A haptic supports the optic around its equator and couples the optic to the capsular bag of the eye. Certain haptic features improve the accommodative performance of the haptic, such that compressive/tensile forces may be more efficiently transferred from the haptic to optic. Furthermore, certain aspects also provide enhanced bag-sizing capability so that the IOL better fits within the capsular bag.
摘要翻译：公开了一种眼内透镜，其具有响应于由眼睛的小环施加的变形力而改变形状的光学元件。触觉件支持其赤道周围的光学器件，并将光学元件耦合到眼睛的囊袋。某些触觉特征改善了触觉的调节性能，使得压缩/拉伸力可以更有效地从触觉传递到光学元件。此外，某些方面还提供增强的袋尺寸能力，使得IOL更适合于囊袋内。

4. 发明申请

WO2010151691A3 ACCOMMODATING INTRAOCULAR LENSES 审中-公开
标题翻译：住院镜片
公开(公告)号：WO2010151691A3
公开(公告)日：2011-03-10
申请号：PCT/US2010039858
申请日：2010-06-24
申请人： ABBOTT MEDICAL OPTICS INC , BUMBALOUGH TIMOTHY R , JAIN RAKHI , CATLIN SCOTT J , YORITA TAMARA J
发明人： BUMBALOUGH TIMOTHY R , JAIN RAKHI , CATLIN SCOTT J , YORITA TAMARA J
IPC分类号： A61F2/16
CPC分类号： A61F2/1613 , A61F2/1624 , A61F2/1635 , A61F2/1648 , A61F2/1694 , A61F2002/1681 , A61F2002/1682 , A61F2002/16901
摘要： An intraocular lens is disclosed, with an optic that changes shape in response to a deforming force exerted by the zonules of the eye. A haptic (50, 60, 70, 90,100, 110, 130, 150, 170) supports the optic around its equator and couples the optic to the capsular bag of the eye. Certain haptic features improve the accommodative performance of the haptic, such that compressive/tensile forces may be more efficiently transferred from the haptic to optic. Furthermore, certain aspects also provide enhanced bag-sizing capability so that the IOL better fits within the capsular bag.
摘要翻译：公开了一种眼内透镜，其具有响应于由眼睛的小环施加的变形力而改变形状的光学元件。触觉（50,60,70,90,100,110,130,150,170）支撑其赤道周围的光学元件，并将光学元件耦合到眼睛的囊袋。某些触觉特征改善了触觉的调节性能，使得压缩/拉伸力可以更有效地从触觉传递到光学元件。此外，某些方面还提供增强的袋尺寸能力，使得IOL更适合于囊袋内。

5. 发明申请

WO2010151693A3 ACCOMMODATING INTRAOCULAR LENSES 审中-公开
标题翻译：住院镜片
公开(公告)号：WO2010151693A3
公开(公告)日：2011-02-17
申请号：PCT/US2010039860
申请日：2010-06-24
申请人： ABBOTT MEDICAL OPTICS INC , BUMBALOUGH TIMOTHY R
发明人： BUMBALOUGH TIMOTHY R
IPC分类号： A61F2/16
CPC分类号： A61F2/1613 , A61F2/1624 , A61F2/1635 , A61F2/1648 , A61F2/1694 , A61F2002/1681 , A61F2002/1682 , A61F2002/16901
摘要： An intraocular lens is disclosed, with an optic that changes shape in response to a deforming force exerted by the zonules of the eye. A haptic (23, 50, 60, 70, 90, 100, 110, 130, 150, 170, 190) supports the optic around its equator and couples the optic to the capsular bag of the eye. Certain haptic features improve the accommodative performance of the haptic, such that compressive/tensile forces may be more efficiently transferred from the haptic to optic. Furthermore, certain aspects also provide enhanced bag-sizing capability so that the IOL better fits within the capsular bag.
摘要翻译：公开了一种眼内透镜，其具有响应于由眼睛的小环施加的变形力而改变形状的光学元件。触觉（23,50,60,70,90,100,110,130,150,170,190）支撑其赤道周围的光学元件，并将光学元件连接到眼睛的囊袋。某些触觉特征改善了触觉的调节性能，使得压缩/拉伸力可以更有效地从触觉传递到光学元件。此外，某些方面还提供增强的袋尺寸能力，使得IOL更适合于囊袋内。

6. 发明申请

WO2010045294A8 INTRAOCULAR LENS AND CAPSULAR RING 审中-公开
标题翻译：内镜透镜和囊状环
公开(公告)号：WO2010045294A8
公开(公告)日：2010-06-03
申请号：PCT/US2009060596
申请日：2009-10-14
申请人： ABBOTT MEDICAL OPTICS INC , BUMBALOUGH TIMOTHY R
发明人： BUMBALOUGH TIMOTHY R
IPC分类号： A61F2/16
CPC分类号： A61F2/1613 , A61F2/1635 , A61F2/1648 , A61F2/1694 , A61F2002/1681 , A61F2002/1682 , A61F2002/169 , A61F2250/0018 , A61F2250/0036 , A61F2250/0037
摘要： A device includes a plurality of ringlets connected together to form a ring having a longitudinal axis. Each ringlet includes a first element and a second element. The first and second elements each extend from a first end through a central portion to a second end. The first and second ends are disposed at radially outer positions with respect to the ring than the central portion. The central portion is longitudinally displaced from the first and second ends. The first and second elements are separated and spaced apart from each other at the central portions thereof and are joined together at the first ends thereof and the second ends thereof. The ringlets are connected together such that the first ends of the elements of one ringlet are connected to the second ends of the elements of an adjacent ringlet.
摘要翻译：一种装置包括连接在一起以形成具有纵向轴线的环的多个小环。每个小环包括第一元件和第二元件。第一和第二元件各自从第一端延伸通过中心部分到第二端。第一和第二端相对于中心部分设置在相对于环的径向外侧位置处。中心部分从第一端和第二端纵向移位。第一和第二元件在其中央部分彼此间隔开并且在其第一端和第二端连接在一起。小环连接在一起，使得一个小环的元件的第一端连接到相邻小环的元件的第二端。

7. 发明申请

WO2009120908A3 INTRAOCULAR LENS HAVING A HAPTIC THAT INCLUDES A CAP 审中-公开
标题翻译：内窥镜包含一个帽子
公开(公告)号：WO2009120908A3
公开(公告)日：2009-11-19
申请号：PCT/US2009038466
申请日：2009-03-26
申请人： ABBOTT MEDICAL OPTICS INC , BUMBALOUGH TIMOTHY R
发明人： BUMBALOUGH TIMOTHY R
IPC分类号： A61F2/16
CPC分类号： A61F2/1635 , A61F2/16 , A61F2/1624 , A61F2/1629 , A61F2/1648 , A61F2002/1682
摘要： An intraocular lens (30) is disclosed, with an adjustable optic (150) that changes shape in response to a deforming force exerted by the zonules of the eye. A haptic (90) supports the optic around its equator and couples the optic to the capsular bag of the eye. The haptic may include a cap (93) on the anterior and/or posterior surfaces of the lens. The lens may include a force transfer member (160), such as a hinge, that couples forces from the haptic to the cap, so that a radial force on the haptic changes the curvature of the cap. The haptic and optic may be refractive index-matched. The cap may be made of the haptic material, which is stiffer than the optic material, and can influence the deformation of the lens during accommodation. A cap on the anterior surface may produce an axial movement of the lens in an anterior direction during accommodation. The cap may also protect the surfaces of the optic during handling and installation.
摘要翻译：公开了一种眼内透镜（30），其具有响应于由眼睛的小区施加的变形力而改变形状的可调节光学元件（150）。触觉（90）支撑其赤道周围的光学器件，并将光学元件耦合到眼睛的囊袋。触觉件可以在透镜的前表面和/或后表面上包括盖（93）。透镜可以包括将力从触觉件与帽接合的力传递构件（例如铰链），从而使触觉件上的径向力改变盖的曲率。触觉和光学可以是折射率匹配的。帽可以由比光学材料更硬的触觉材料制成，并且可以在调节期间影响镜片的变形。在前表面的帽可以在调节期间在前方向产生透镜的轴向移动。在操作和安装过程中，盖子还可以保护光学元件的表面。

8. 发明申请

WO2008082853A2 PRE-STRESSED HAPTIC FOR ACCOMMODATING INTRAOCULAR LENS 审中-公开
标题翻译：预先配合眼科镜片
公开(公告)号：WO2008082853A2
公开(公告)日：2008-07-10
申请号：PCT/US2007/086832
申请日：2007-12-07
申请人： ADVANCED MEDICAL OPTICS, INC. , BRADY, Daniel, G. , WOODS, Randall, L. , BUMBALOUGH, Timothy, R. , GERAGHTY, Edward, P.
发明人： BRADY, Daniel, G. , WOODS, Randall, L. , BUMBALOUGH, Timothy, R. , GERAGHTY, Edward, P.
IPC分类号： A61F2/16
CPC分类号： A61F2/1635 , A61F2002/1682
摘要： An intraocular lens is disclosed, with an optic that changes shape in response to a deforming force exerted by the zonules of the eye. A haptic supports the optic around its equator and couples the optic to the capsular bag of the eye. The haptic may be pre-stressed before the optic is placed within it. After such placement, the pre-stress may be relieved, and the haptic may produce stress in the optic. The pre-stress may produce a radial tension or a radial compression in the optic. Alternatively, once the optic is placed within the haptic, both may undergo a process that changes the size and/or shape of one with respect to the other, causing a stress within the optic. This process may produce a radial tension or a radial compression in the optic. The haptic may include an annular ring having outer and inner diameters that may depend on the stiffness of the haptic.
摘要翻译：公开了一种眼内透镜，其具有响应于由眼睛的小环施加的变形力而改变形状的光学元件。触觉件支持其赤道周围的光学器件，并将光学元件耦合到眼睛的囊袋。在光学元件放置在其中之前，触觉可以被预应力。在这种放置之后，预应力可以减轻，并且触觉可能在视神经中产生应力。预应力可能在光学元件中产生径向张力或径向压缩。或者，一旦将光学元件放置在触觉件内，则两者都可以经历一种相对于另一个改变尺寸和/或形状的过程，从而导致光学元件内的应力。该过程可能在光学元件中产生径向张力或径向压缩。触觉件可以包括具有取决于触觉件的刚度的外部和内部直径的环形环。

9. 发明申请

WO2011031557A1 FIXATION OF OPTHALMIC IMPLANTS 审中-公开
标题翻译： OPALALMIC植入物的固定
公开(公告)号：WO2011031557A1
公开(公告)日：2011-03-17
申请号：PCT/US2010/047011
申请日：2010-08-27
申请人： ABBOTT MEDICAL OPTICS INC. , KADZIAUSKAS, Kenneth, E. , REISIN, Carina, R. , BUMBALOUGH, Timothy, R.
发明人： KADZIAUSKAS, Kenneth, E. , REISIN, Carina, R. , BUMBALOUGH, Timothy, R.
IPC分类号： A61F2/16 , A61F9/007 , A61F2/00
CPC分类号： A61F2/1624 , A61F2/1635 , A61F9/00781 , A61F2002/009 , A61F2002/1681 , A61F2002/1682 , A61F2220/0008 , A61F2220/0016 , A61F2250/0003
摘要： An accommodating intraocular lens (50) is disclosed, with an optic (52) that changes shape in response to an ocular force exerted by the zonules of the eye. A haptic (154) supports the optic around its equator and couples the optic to the capsular bag of the eye. A surface adherent (60,62,64,66,68,70,72,74) improves the accommodative performance of the haptic, such that compressive/tensile forces may be more efficiently transferred from the haptic to optic. One way to enhance force transfer is to provide a surface layer of an adhesive to the haptic and/or optic, for instance a reversible bioadhesive material. Or, portions of the exterior surface of the IOL may have microfibers thereon that mimic the adhesive properties of Gecko feet. Another aspect is application of a reversible bioadhesive material to the interior of the empty capsular bag prior to introduction of an injectable polymer IOL.
摘要翻译：公开了一种适应性眼内透镜（50），其具有响应于由眼睛的小区施加的眼部力而改变形状的光学元件（52）。触觉（154）支撑其赤道周围的光学器件，并将光学元件耦合到眼睛的囊袋。表面粘附（60,62,64,66,68,70,72,74）改善了触觉的调节性能，使得压缩/拉伸力可以更有效地从触觉传递到光学元件。增强力传递的一种方式是向触觉和/或光学元件提供粘合剂的表面层，例如可逆的生物粘附材料。或者，IOL的外表面的部分可能在其上具有模拟Gecko脚的粘合性质的微纤维。另一方面是在引入可注射聚合物IOL之前将可逆生物粘附材料施用于空的囊袋的内部。

10. 发明申请

WO2010135685A1 OPHTHALMIC LENSES WITH ENHANCED SURFACE AND METHODS OF FABRICATION THEREOF 审中-公开
标题翻译：具有增强表面的眼镜及其制造方法
公开(公告)号：WO2010135685A1
公开(公告)日：2010-11-25
申请号：PCT/US2010/035832
申请日：2010-05-21
申请人： ABBOTT MEDICAL OPTICS INC. , BUMBALOUGH, Timothy, R. , GERAGHTY, Edward , BRADY, Daniel, G.
发明人： BUMBALOUGH, Timothy, R. , GERAGHTY, Edward , BRADY, Daniel, G.
IPC分类号： A61F2/16
CPC分类号： A61F2/1613 , A61F2/1616 , A61F2/1618 , A61F2/1648 , A61F2002/1681 , A61F2002/1699 , A61F2210/0076 , A61F2240/001 , A61F2250/0053 , B29D11/023
摘要： An ophthalmic lens (100) for providing enhanced vision includes a finished optic (105) comprising a base optic (115) and a shell (135). The base optic has an anterior surface (120) and an opposing posterior surface (125), at least one of the surfaces having a first value of a surface quality parameter. The shell includes a membrane (140, 150) including an inner surface and an outer surface, the inner surface covering one or more of the surfaces of the base optic. The outer surface has a second value of the surface quality parameter, wherein the second value is greater than the first value.
摘要翻译：用于提供增强视觉的眼用透镜（100）包括包括基底光学元件（115）和外壳（135）的成品光学元件（105）。基部光学元件具有前表面（120）和相对的后表面（125），至少一个表面具有表面质量参数的第一值。壳体包括包括内表面和外表面的膜（140,150），内表面覆盖基底光学元件的一个或多个表面。外表面具有表面质量参数的第二值，其中第二值大于第一值。

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