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1. 发明申请

WO2009042135A2 MRI SURGICAL SYSTEMS FOR REAL-TIME VISUALIZATIONS USING MRI IMAGE DATA AND PREDEFINED DATA OF SURGICAL TOOLS 审中-公开
标题翻译：使用MRI图像数据和外科手术预测数据进行实时可视化的MRI外科系统
公开(公告)号：WO2009042135A2
公开(公告)日：2009-04-02
申请号：PCT/US2008011050
申请日：2008-09-24
申请人： SURGIVISION INC , CEDARA SOFTWARE CORP , JENKINS KIMBLE L , PIFERI PETER , HOTTE PHILIP BRADLEY , FARBEROV PAVEL , ORR TIMOTHY NEIL , GEIGER PAUL ARTHUR
发明人： JENKINS KIMBLE L , PIFERI PETER , HOTTE PHILIP BRADLEY , FARBEROV PAVEL , ORR TIMOTHY NEIL , GEIGER PAUL ARTHUR
IPC分类号： G01R33/28 , A61B19/00 , G01R33/34
CPC分类号： G01R33/283 , A61B5/055 , A61B5/0555 , A61B5/4064 , A61B34/10 , A61B34/25 , A61B34/71 , A61B34/74 , A61B90/11 , A61B90/14 , A61B90/361 , A61B90/37 , A61B2017/00212 , A61B2017/00911 , A61B2017/3407 , A61B2017/3409 , A61B2034/101 , A61B2034/107 , A61B2034/252 , A61B2034/254 , A61B2034/256 , A61B2090/103 , A61B2090/306 , A61B2090/3614 , A61B2090/373 , A61B2090/374 , A61B2090/3933 , A61B2090/3937 , A61B2090/395 , A61B2090/3954 , A61B2090/3983 , A61N1/36014 , A61N1/372 , G01R33/286 , G01R33/287 , G01R33/34046 , G01R33/3415
摘要： MRI-Surgical systems include: (a) at least one MRI-compatible surgical tool; (b) a circuit adapted to communicate with an MRI scanner; and (c) at least one display in communication with the circuit. The circuit electronically recognizes predefined physical characteristics of the at least one tool to automatically segment MR image data provided by the MRI scanner whereby the at least one tool constitutes a point of interface with the system. The circuit is configured to provide a User Interface that defines workflow progression for an MRI-guided surgical procedure and allows a user to select steps in the workflow, and wherein the circuit is configured to generate multi-dimensional visualizations using the predefined data of the at least one tool and data from MRI images of the patient in substantially real time during the surgical procedure.
摘要翻译： MRI手术系统包括：（a）至少一个与MRI兼容的手术工具; （b）适于与MRI扫描器通信的电路; 和（c）与电路通信的至少一个显示器。所述电路电子地识别所述至少一个工具的预定义的物理特性，以自动分割由所述MRI扫描仪提供的MR图像数据，由此所述至少一个工具构成与所述系统的界面点。电路被配置为提供用于界定MRI引导外科手术的工作进程的用户界面，并且允许用户选择工作流程中的步骤，并且其中电路被配置为使用预先确定的at的数据生成多维可视化在外科手术过程中基本上实时地至少一个工具和来自患者的MRI图像的数据。

2. 发明申请

WO2010034099A1 AC-PC SEGMENTATION SYSTEM AND METHOD 审中-公开
标题翻译： AC-PC分段系统和方法
公开(公告)号：WO2010034099A1
公开(公告)日：2010-04-01
申请号：PCT/CA2009/000444
申请日：2009-04-09
申请人： CEDARA SOFTWARE CORP. , GEIGER, Paul, Arthur
发明人： GEIGER, Paul, Arthur
IPC分类号： A61B6/02 , A61B5/055 , A61B6/03 , A61G99/00
CPC分类号： G06T3/0031 , A61B5/0555 , G01R33/546 , G01R33/5608 , G06T7/13 , G06T7/68 , G06T7/75 , G06T2207/10072 , G06T2207/30016
摘要： A computer-implemented system and method of determining anterior commissure (AC) and posterior commissure (PC) points in a volumetric neuroradiological image. The method includes determining, by a computer, a mid-sagittal plane estimate to extract a mid-sagittal plane image from the volumetric neuroradiological image, and AC and PC point estimates in the mid-sagittal plane image. The method further includes determining, by the computer, a refined mid-sagittal plane estimate from the AC and PC point estimates to extract a refined mid-sagittal plane image, the AC point from the refined mid-sagittal plane image, and the PC point from the refined mid-sagittal plane image and the AC point.
摘要翻译：一种计算机实现的系统和方法，用于确定体积神经放射学图像中的前连合（AC）和后连合点（PC）点。该方法包括由计算机确定中矢状面估计以从体积神经放射学图像提取中矢状面平面图像，以及在矢状面中图像中的AC和PC点估计。该方法还包括由计算机确定来自AC和PC点估计的精确中矢状面估计，以提取精确的中矢状面平面图像，来自精练中矢状面平面图像的AC点和PC点从精准的中矢状平面图像和AC点。

3. 发明申请

WO2008034222A1 SYSTEM AND METHOD FOR SHUTTER DETECTION 审中-公开
标题翻译：快速检测系统及方法
公开(公告)号：WO2008034222A1
公开(公告)日：2008-03-27
申请号：PCT/CA2007/001636
申请日：2007-09-19
申请人： CEDARA SOFTWARE CORP. , YU, Songyang , ACCOMAZZI, Vittorio , GEIGER, Paul
发明人： YU, Songyang , ACCOMAZZI, Vittorio , GEIGER, Paul
IPC分类号： G06T5/00 , A61B6/00 , G06T7/60
CPC分类号： G06T5/005 , A61B6/5252 , G06T7/12 , G06T7/194 , G06T2207/10116 , G06T2207/20016 , G06T2207/30004
摘要： A method for removing shutter areas in an image, in particular an x-ray image is provided. Edges are examined in a multi-resolution image pyramid and evaluated to determine potential shutter blade candidates defining the shutter areas. Heuristic rules and/or an automatic classifier such as a Neuronal Network, are applied to distinguish true shutter blades from false positives. The rule set and the classifier are based on a set of features extracted from the potential shutter blade candidates as well as predetermined knowledge of the expected placement of the shutter, human anatomy. Up to four shutter blades are expected to be detected and based on these blades, the bright areas in the image that occur due to the shutters are removed.
摘要翻译：提供了用于去除图像中的快门区域的方法，特别是X射线图像。在多分辨率图像金字塔中检查边缘并进行评估以确定限定快门区域的潜在快门叶片候选。应用启发式规则和/或自动分类器（如神经元网络）来区分真正的快门叶片与假阳性。规则集和分类器基于从潜在的快门叶片候选中提取的一组特征以及对快门，人体解剖学的预期放置的预定知识。预计最多可以检测到四个快门叶片，并且基于这些刀片，由于百叶窗而发生的图像中的明亮区域被去除。

4. 发明申请

WO2009042135A3 MRI SURGICAL SYSTEMS FOR REAL-TIME VISUALIZATIONS USING MRI IMAGE DATA AND PREDEFINED DATA OF SURGICAL TOOLS 审中-公开
公开(公告)号：WO2009042135A3
公开(公告)日：2009-04-02
申请号：PCT/US2008/011050
申请日：2008-09-24
申请人： SURGIVISION, INC. , CEDARA SOFTWARE CORPORATION , JENKINS, Kimble, L. , PIFERI, Peter , HOTTE, Philip, Bradley , FARBEROV, Pavel , ORR, Timothy, Neil , GEIGER, Paul, Arthur
发明人： JENKINS, Kimble, L. , PIFERI, Peter , HOTTE, Philip, Bradley , FARBEROV, Pavel , ORR, Timothy, Neil , GEIGER, Paul, Arthur
IPC分类号： G01R33/28 , G01R33/34 , A61B19/00
摘要： MRI-Surgical systems include: (a) at least one MRI-compatible surgical tool (50); (b) a circuit (30c) adapted to communicate with an MRI scanner (20); and (c) at least one display (32) in communication with the circuit. The circuit electronically recognizes predefined physical characteristics of the at least one tool to automatically segment MR image data provided by the MRI scanner whereby the at least one tool constitutes a point of interface with the system. The circuit is configured to provide a User Interface that defines workflow progression for an MRI-guided surgical procedure and allows a user to select steps in the workflow, and wherein the circuit is configured to generate multi-dimensional visualizations using the predefined data of the at least one tool and data from MRI images of the patient in substantially real time during the surgical procedure.

5. 发明申请

WO2005073914A1 SYSTEM AND METHOD FOR APPLYING ACTIVE APPEARANCE MODELS TO IMAGE ANALYSIS 审中-公开
标题翻译：将活动外观模型应用于图像分析的系统和方法
公开(公告)号：WO2005073914A1
公开(公告)日：2005-08-11
申请号：PCT/CA2004/000134
申请日：2004-01-30
申请人： CEDARA SOFTWARE CORPORATION , ACCOMAZZI, Vittorio , BORDEGARI, Diego , JAN, Ellen , TATE, Peter , GEIGER, Paul
发明人： ACCOMAZZI, Vittorio , BORDEGARI, Diego , JAN, Ellen , TATE, Peter , GEIGER, Paul
IPC分类号： G06T7/00
CPC分类号： G06K9/621 , G06T7/0012 , G06T7/11 , G06T7/149 , G06T7/251 , G06T2207/20081 , G06T2207/30004
摘要： An image processing system and method having a statistical appearance model for interpreting a digital image. The appearance model has at least one model parameter. The system and method comprises a two dimensional first model object including an associated first statistical relationship, the first model object configured for deforming to approximate,a shape and texture of a two dimensional first target object in the digital image. Also included is a search module for selecting and applying the first model object to the image for generating a two dimensional first output object approximating the shape and texture of the first target object, the search module calculating a first error between the first output object and the first target object. Also included is an output module for providing data representing the first output object to an output. The processing system uses interpolation for improving image segmentation, as well as multiple models optimised for various target object configurations. Also included is a model labelling that is associated with model parameters, such that the labelling is attributed to solution images to aid in patient diagnosis.
摘要翻译：一种具有用于解释数字图像的统计外观模型的图像处理系统和方法。外观模型至少有一个模型参数。所述系统和方法包括包括相关联的第一统计关系的二维第一模型对象，所述第一模型对象被配置为在数字图像中变形以近似二维第一目标对象的形状和纹理。还包括一个搜索模块，用于选择和应用第一模型对象到图像上，用于生成近似第一目标对象的形状和纹理的二维第一输出对象，搜索模块计算第一输出对象和第一个目标对象。还包括用于将表示第一输出对象的数据提供给输出的输出模块。处理系统使用内插来改善图像分割，以及针对各种目标对象配置优化的多个模型。还包括与模型参数相关联的模型标签，使得标签归因于溶液图像以辅助患者诊断。

6. 发明申请

WO2008052312A1 SYSTEM AND METHOD FOR SEGMENTING A REGION IN A MEDICAL IMAGE 审中-公开
标题翻译：用于在医学图像中分割区域的系统和方法
公开(公告)号：WO2008052312A1
公开(公告)日：2008-05-08
申请号：PCT/CA2007/001772
申请日：2007-10-10
申请人： CEDARA SOFTWARE CORP. , GEIGER, Paul , ACCOMAZZI, Vittorio
发明人： GEIGER, Paul , ACCOMAZZI, Vittorio
IPC分类号： G06T7/60 , A61B8/14 , G06T5/00
CPC分类号： G01S7/52084 , A61B8/13 , A61B8/469 , G01S7/52036 , G01S7/52074 , G01S15/8993 , G06K9/4638 , G06K2009/366 , G06K2209/051 , G06T7/12 , G06T7/149 , G06T2207/10132 , G06T2207/20092
摘要： A method and computer program are provided for segmenting a prostate from a medical image such as an ultrasound image. Each slice in a study is analysed and uses a manual initialization to obtain an initial contour, in which a user selects initial points that are automatically rendered on the image. An automatic refinement stage then snaps the contour to the prostate boundary in the image based on a pre-stored anatomical atlas and edge information obtained from the image. A manual adjustment stage may then be performed and if selected, the contour is automatically propagated to the next image slice to avoid the manual initialization. An auxiliary image slice may be referred to, which indicates how the prostate shape changes from slice to slice, e.g. by providing a perpendicular profile.
摘要翻译：提供了一种用于从诸如超声图像的医学图像分割前列腺的方法和计算机程序。分析研究中的每个切片，并使用手动初始化来获取初始轮廓，其中用户选择自动呈现在图像上的初始点。然后，自动细化阶段基于从图像获得的预先存储的解剖图谱和边缘信息将轮廓锁定到图像中的前列腺边界。然后可以执行手动调整阶段，如果选择，轮廓将自动传播到下一个图像切片，以避免手动初始化。可以参考辅助图像切片，其指示前列腺形状如何从切片切换到切片。通过提供垂直轮廓。

7. 发明申请

WO2007059602A1 METHOD AND SYSTEM FOR ENHANCING DIGITAL IMAGES 审中-公开
标题翻译：用于增强数字图像的方法和系统
公开(公告)号：WO2007059602A1
公开(公告)日：2007-05-31
申请号：PCT/CA2006/001707
申请日：2006-10-19
申请人： CEDARA SOFTWARE CORP. , GEIGER, Paul , ACCOMAZZI, Vittorio
发明人： GEIGER, Paul , ACCOMAZZI, Vittorio
IPC分类号： G06T5/00
CPC分类号： G06T5/20 , G06T5/004 , G06T5/007 , G06T2207/20016 , G06T2207/20032 , G06T2207/20048 , G06T2207/30004
摘要： A system and method for enhancing digital images is described. A digital image is transformed into a series of decomposed images in frequency bands, or different resolution grids A decomposed image is noise suppressed and contrast enhanced Representative value of signal at each pixel is computed based on contributions to signals from pixels in a neighborhood of the pixel. Lookup tables are applied to pixel values to selectively enhance signal in a predetermined range of signal strength. Another set of lookup tables are applied to pixel values to suppress noise components contained therein Optionally, operations are applied to decomposed images to suppress quantum noise, enhance object edges or enhance global contrast, among others These decomposed images, after signal enhancement and noise suppression, are then recombined to result in an enhanced image
摘要翻译：描述了用于增强数字图像的系统和方法。数字图像被转换成频带中的一系列分解图像，或不同的分辨率网格A分解图像被噪声抑制和对比度增强基于对像素附近的像素的信号的贡献来计算每个像素处的信号的代表值。将查找表应用于像素值以选择性地增强在预定信号强度范围内的信号。将另一组查找表应用于像素值以抑制包含在其中的噪声分量。可选地，将操作应用于分解图像以抑制量子噪声，增强对象边缘或增强全局对比度等。在信号增强和噪声抑制之后，这些分解图像，然后重新组合以产生增强的图像

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