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1. 发明申请

WO2010005897A3 APPARATUS FOR OCCLUDING A FALLOPIAN TUBE 审中-公开
标题翻译：装置倒装管的装置
公开(公告)号：WO2010005897A3
公开(公告)日：2010-04-22
申请号：PCT/US2009049689
申请日：2009-07-06
申请人： COHEREX MEDICAL INC , CARTER PHILLIP J , LINDER RICHARD J , JONES RANDALL K , MILES SCOTT D , DAVIS CLARK C , EDMISTON DARYL R , FOX DEWAYNE C
发明人： CARTER PHILLIP J , LINDER RICHARD J , JONES RANDALL K , MILES SCOTT D , DAVIS CLARK C , EDMISTON DARYL R , FOX DEWAYNE C
IPC分类号： A61F6/22 , A61B17/12
CPC分类号： A61F6/225
摘要： The present invention is directed to a medical device for occluding a fallopian tube for contraception and sterilization. The medical device includes an outer member (12), an inner member (14) and a tissue growth member (16). The outer member includes an outer surface (20) and an inner surface (22), wherein the inner surface defines a bore (24) in the outer member. The inner member is configured to be positioned within the bore of the outer member. The tissue growth member is attached to the outer surface of the outer member and is configured to induce tissue growth thereto. With this arrangement, the medical device can be implanted within the fallopian tube and serve as an occluding device therein. If desired, the medical device can be partially removed from the fallopian tube to restore the ability for conception.
摘要翻译：本发明涉及一种用于闭塞输卵管用于避孕和灭菌的医疗装置。医疗装置包括外部构件（12），内部构件（14）和组织生长构件（16）。外部构件包括外表面（20）和内表面（22），其中内表面在外部构件中限定孔（24）。内部构件构造成定位在外部构件的孔内。组织生长构件附接到外部构件的外表面并且构造成诱导组织生长。通过这种布置，医疗装置可以植入输卵管内并用作其中的闭塞装置。如果需要，医疗设备可以部分地从输卵管中移除以恢复受孕的能力。

2. 发明申请

WO2009094588A2 SYSTEMS AND METHODS FOR REDUCTION OF ATRIAL FIBRILLATION 审中-公开
标题翻译：用于减少心房颤动的系统和方法
公开(公告)号：WO2009094588A2
公开(公告)日：2009-07-30
申请号：PCT/US2009031903
申请日：2009-01-23
申请人： COHEREX MEDICAL INC , DAVIS CLARK C , LINDER RICHARD J , MILES SCOTT D , EDMISTON DARYL R
发明人： DAVIS CLARK C , LINDER RICHARD J , MILES SCOTT D , EDMISTON DARYL R
IPC分类号： A61B5/027 , A61M25/00
CPC分类号： A61B18/1492 , A61B5/042 , A61B18/082 , A61B18/18 , A61B2017/00367 , A61B2017/0046 , A61B2017/00575 , A61B2017/00867 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00351 , A61B2018/00375 , A61B2018/00577 , A61B2018/00839 , A61B2018/1435 , A61M2025/0183 , A61M2025/1047 , A61M2025/1052
摘要： Embodiments of the present invention are directed to ablation catheter systems configured, for example, to ablate tissue adjacent an ostium of the pulmonary vein in a left atria of a heart, hi one embodiment, an ablation catheter system includes a handle including an actuator and a catheter coupled to the handle defining a lumen extending through a length of the catheter, the catheter including a tip portion at a distal end thereof. The ablation catheter system may also include an electrode coupled to the handle with lines extending through the lumen of the catheter, the electrode being configured to be constrained within the tip portion of the catheter and configured to be deployed from the tip portion and self expand to an expanded configuration. With this arrangement, the electrode is configured to self expand to a conical configuration with a tip portion configured to be disposed within the pulmonary vein.
摘要翻译：本发明的实施例涉及消融导管系统，其被配置为例如消融心脏的左心房中的肺静脉口附近的组织。在一个实施例中，消融导管系统包括手柄，该手柄包括致动器和连接至所述手柄的导管，所述导管限定延伸穿过所述导管的一段的内腔，所述导管在其远端处包括尖端部分。消融导管系统还可以包括电极，该电极通过延伸穿过导管的管腔的线连接到手柄，该电极被配置为被约束在导管的尖端部分内并且被配置为从尖端部分展开并且自扩张到一个扩展的配置。利用这种布置，电极被配置为自膨胀成圆锥形构造，其中末端部分被配置为布置在肺静脉内。

3. 发明申请

WO2006075990A3 STITCHING DEVICE AND METHODS OF USE 审中-公开
标题翻译：缝合装置及其使用方法
公开(公告)号：WO2006075990A3
公开(公告)日：2009-04-16
申请号：PCT/US2005009601
申请日：2005-03-22
申请人： RUBICON MEDICAL INC , HAMATAKE BRET , EDMISTON DARYL R , SCHLEGEL KARRI L , JOHNSON STEVEN W
发明人： HAMATAKE BRET , EDMISTON DARYL R , SCHLEGEL KARRI L , JOHNSON STEVEN W
IPC分类号： B23P11/00 , A61M29/00 , B21D39/00 , B23P19/04
CPC分类号： A61F2/01 , A61F2/013 , Y10T29/49826 , Y10T29/49908 , Y10T29/53657
摘要： A stitching device (110) and method of operating the stitching device to form an embolic protection device is disclosed. The stitching device (110) includes a clamping assembly (114) and an advancing assembly (116). The clamping assembly (114) holds a restraining member about a filter assembly while the advancing assembly threads or stitches a securing member through the restraining member. The clamping assembly (114) includes a first clamping portion (118) and a second clamping portion (120), each having an upper row of teeth and a lower row of teeth divided by a channel. The advancing assembly (116) includes a threading assembly (186) with an engagement member (200) for engaging and advancing the securing member.
摘要翻译：公开了缝合装置（110）和操作缝合装置以形成栓塞保护装置的方法。缝合装置（110）包括夹紧组件（114）和前进组件（116）。夹持组件（114）将限制构件保持在过滤器组件周围，而前进组件通过限制构件螺纹或缝合固定构件。夹紧组件（114）包括第一夹紧部分（118）和第二夹持部分（120），每个夹紧部分具有上排的齿和由一个通道分开的下排齿。前进组件（116）包括具有用于接合和推进固定构件的接合构件（200）的螺纹组件（186）。

4. 发明申请

WO2007140419A3 METHODS AND SYSTEMS FOR CLOSURE OF A PATENT FORAMEN OVALE 审中-公开
标题翻译：用于封闭玻璃瓶的方法和系统
公开(公告)号：WO2007140419A3
公开(公告)日：2008-09-25
申请号：PCT/US2007069994
申请日：2007-05-30
申请人： COHEREX MEDICAL INC , FOX DEWAYNE C , EDMISTON DARYL R , MILES SCOTT D , DAVIS CLARK C , WHISENANT BRIAN K
发明人： FOX DEWAYNE C , EDMISTON DARYL R , MILES SCOTT D , DAVIS CLARK C , WHISENANT BRIAN K
IPC分类号： A61B18/18
CPC分类号： A61B17/0057 , A61B18/1492 , A61B2017/00026 , A61B2017/00084 , A61B2017/00575 , A61B2017/00623 , A61B2017/00867 , A61B2018/00791 , A61B2018/00875 , A61B2090/378
摘要： A medical device for reducing the size of a Patent Foramen Ovale is disclosed. The medical device can include a first electrode (116a), a second electrode (111a), and at least one sensor mounted to at least one of the first electrode or the second electrode, the at least one sensor adapted to sense at least one operating parameter of the medical device or the patient to facilitate closure of the Patent Foramen Ovale. The medical device can also include a delivery shaft (120c) coupled to the first electrode, wherein the delivery shaft includes an indicia for determining the position of the first electrode relative to the second electrode. A method for determining a characteristic of an internal tissue opening is also disclosed. The method can include the steps of introducing a detectable fluid in the right atrium of a heart and then detecting the location of the detectable fluid in the heart.
摘要翻译：公开了一种用于减小专利孔径的医疗装置。医疗装置可以包括第一电极（116a），第二电极（111a）和安装到第一电极或第二电极中的至少一个的至少一个传感器，所述至少一个传感器适于感测至少一个操作医疗设备或患者的参数，以便于关闭专利孔洞。医疗装置还可以包括联接到第一电极的输送轴（120c），其中输送轴包括用于确定第一电极相对于第二电极的位置的标记。还公开了一种用于确定内部组织开口的特性的方法。该方法可以包括在心脏的右心房中引入可检测流体，然后检测心脏中可检测流体的位置的步骤。

5. 发明申请

WO2007092860A2 PATENT FORAMEN OVALE CLOSURE DEVICE AND METHODS FOR DETERMINING RF DOSE FOR PATENT FORAMEN OVALE CLOSURE 审中-公开
标题翻译：专利文献OVALE封闭装置及其用于确定OVO封闭专利的RF剂量的方法
公开(公告)号：WO2007092860A2
公开(公告)日：2007-08-16
申请号：PCT/US2007/061713
申请日：2007-02-06
申请人： COHEREX MEDICAL, INC. , WHISENANT, Brian, K. , DAVIS, Clark, C. , MILES, Scott, D. , LINDER, Richard, J. , EDMISTON, Daryl, R.
发明人： WHISENANT, Brian, K. , DAVIS, Clark, C. , MILES, Scott, D. , LINDER, Richard, J. , EDMISTON, Daryl, R.
CPC分类号： A61B5/053
摘要： A medical system and device for use in delivering RF energy to a tissue opening and a method for determining an RP dose is disclosed. In one embodiment, the medical device includes an electrode or anchor and one or more devices, such as an impedance electrode, RF electrode and/or thermocouple. The electrode or anchor can be deployed from a delivery shaft inside the left atrium, for example, of a heart and substantially conform to the tissue proximate the tissue opening. Tissue characteristics, such as temperature and/or impedance, can be measured, before, during and after application of RF energy to the tissue, by one or more devices to determine an RF dose. After energy is applied to the tissue between the left and right electrodes, the left electrode can be removed from the left atrium by being received back into the delivery shaft and the delivery shaft thereafter removed from the opening.
摘要翻译：公开了一种用于向组织开口输送RF能量的医疗系统和装置以及用于确定RP剂量的方法。在一个实施例中，医疗装置包括电极或锚定器以及一个或多个装置，例如阻抗电极，RF电极和/或热电偶。电极或锚固件可以从左心房内的输送轴例如心脏部署并且基本上符合组织开口附近的组织。组织特征如温度和/或阻抗可以在RF能量施加到组织之前，期间和之后由一个或多个装置测量以确定RF剂量。在将能量施加到左右电极之间的组织之后，左电极可以通过被收回到输送轴中而从左心房移除，此后从开口排出输送轴。

6. 发明申请

WO2007038609A2 COMPLIANT ELECTRODE FOR PATENT FORAMEN OVALE CLOSURE DEVICE 审中-公开
标题翻译：符合专利法案的电弧封闭装置
公开(公告)号：WO2007038609A2
公开(公告)日：2007-04-05
申请号：PCT/US2006/037691
申请日：2006-09-26
申请人： COHEREX MEDICAL, INC. , WHISENANT, Brian, K. , DAVIS, Clark, C. , EDMISTON, Daryl, R.
发明人： WHISENANT, Brian, K. , DAVIS, Clark, C. , EDMISTON, Daryl, R.
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B2017/00575 , A61B2017/00867 , A61B2018/00214 , A61B2018/00351 , A61B2018/0063 , A61B2018/1435 , A61B2018/1467 , A61B2018/1475 , A61B2090/3966 , C08L2201/12
摘要： A medical device for use in delivering RF energy to a tissue opening is disclosed. In one embodiment, the medical device comprises a compliant electrode. The compliant electrode can include a shape memory material, such as NITINOL, to facilitate the electrode having at least one relaxed orientation. The electrode can be deployed from a delivery shaft inside the left atrium, for example, of a heart through the delivery shaft. The electrode can be configured to substantially conform to the tissue proximate the tissue opening. After energy is applied to the tissue between the left and right electrodes, the left electrode can be removed from the left atrium by being received back into the delivery shaft and the delivery shaft thereafter removed from the opening.
摘要翻译：公开了用于将RF能量递送到组织开口的医疗装置。在一个实施例中，医疗装置包括柔性电极。柔性电极可以包括形状记忆材料，例如NITINOL，以促进电极具有至少一个松弛取向。电极可以通过输送轴从例如心脏的左心房内的输送轴展开。电极可以被配置成基本符合靠近组织开口的组织。在向左右电极之间的组织施加能量后，通过将左电极收回到输送轴中并且随后从开口移除输送轴，左电极可以从左心房移除。

7. 发明申请

WO2009155571A1 CLOT RETRIEVAL METHOD AND DEVICE 审中-公开
标题翻译：衣物检索方法和装置
公开(公告)号：WO2009155571A1
公开(公告)日：2009-12-23
申请号：PCT/US2009/048049
申请日：2009-06-19
申请人： COHEREX MEDICAL, INC. , LINDER, Richard, J. , EDMISTON, Daryl, R.
发明人： LINDER, Richard, J. , EDMISTON, Daryl, R.
IPC分类号： A61B17/22 , A61B17/221
CPC分类号： A61B17/221 , A61B17/22031 , A61B17/22032 , A61B2017/22034 , A61B2017/22094
摘要： Devices, systems and methods for retrieving clot material from a vasculature lumen are provided. In one embodiment, a medical device includes a handle, a catheter, a tether member and a clot retrieval element. The catheter extends from the handle and the clot retrieval element is configured to be positioned within a distal portion of the catheter with the tether member extending between the handle and the clot retrieval element. The clot retrieval element is configured to be deployed from within the catheter so that the catheter moves proximally relative to and separate from the clot retrieval element while maintaining attachment to the clot retrieval element via the tether member. Further, the clot retrieval element is configured to be pulled by the tether member to abut against a distal side of a clot with proximal movement of the tether member to pull the clot from the vasculature lumen.
摘要翻译：提供了用于从脉管系统腔内检索凝块材料的装置，系统和方法。在一个实施例中，医疗装置包括手柄，导管，系绳构件和凝块回收元件。导管从手柄延伸并且凝块回收元件构造成定位在导管的远端部分内，系链构件在手柄和凝块回收元件之间延伸。凝块回收元件构造成从导管内展开，使得导管相对于凝块回收元件并且与凝块回收元件分离，同时通过绳索构件保持与凝块回收元件的连接。此外，凝块回收元件被构造成被系绳构件拉动以抵靠凝块的远侧，并且系绳构件的近端运动以从脉管系统腔拉动凝块。

8. 发明申请

WO2009052432A3 MEDICAL DEVICE FOR MODIFICATION OF LEFT ATRIAL APPENDANGE AND RELATED SYSTEMS AND METHODS 审中-公开
标题翻译：用于修改左心室附件的医疗装置及相关系统及方法
公开(公告)号：WO2009052432A3
公开(公告)日：2009-07-30
申请号：PCT/US2008080374
申请日：2008-10-17
申请人： COHEREX MEDICAL INC , MILES SCOTT D , LINDER RICHARD J , DAVIS CLARK C , WHISENANT BRIAN K , EDMISTON DARYL R , FOX DEWAYNE C
发明人： MILES SCOTT D , LINDER RICHARD J , DAVIS CLARK C , WHISENANT BRIAN K , EDMISTON DARYL R , FOX DEWAYNE C
IPC分类号： A61B17/12
CPC分类号： A61B17/12122 , A61B17/00491 , A61B17/12022 , A61B17/1214 , A61B17/1215 , A61B17/12159 , A61B17/12172 , A61B17/12186 , A61B17/1219 , A61B2017/00243 , A61B2017/00898 , A61B2017/0412 , A61B2017/0427 , A61B2017/0649 , A61B2017/1205
摘要： Several embodiments are set forth of devices, systems and methods for modifying an atrial appendage such as a left atrial appendage (LAA). In one embodiment, a device includes a body (300, 320) that is collapsible and self -expanding. The body includes a textured surface with protruding portions (304, 322) and recessed portions (306,326). The body may be formed of a reticulated foam material and may exhibit a substantially spherical geometry or a truncated spherical geometry. The body may be substantially hollow. In one embodiment, portions of the textured surface may be metalized or have a coating placed thereon to enhance frictional engagement of the body with the atrial appendage wall. In another embodiment (360), a mesh bag (362) is disposed within an LAA and one or more self- expanding bodies (364) are disposed within the mesh bag. The mesh bag is then secured to retain the self -expanding bodies within the bag and the LAA.
摘要翻译：阐述用于修改诸如左心耳（LAA）的心房附件的装置，系统和方法的几个实施例。在一个实施例中，装置包括可折叠和自展开的主体（300,320）。主体包括具有突出部分（304,322）和凹陷部分（306,326）的织纹表面。主体可以由网状泡沫材料形成，并且可以呈现基本上球形的几何形状或截顶的球形几何形状。身体可以是基本上中空的。在一个实施例中，纹理表面的部分可以被金属化或者具有放置在其上的涂层，以增强身体与心耳壁的摩擦接合。在另一实施例（360）中，网袋（362）设置在LAA内，并且一个或多个自扩张体（364）设置在网袋内。然后将网袋固定，以将自发展体保持在袋和LAA内。

9. 发明申请

WO2007092860A3 PATENT FORAMEN OVALE CLOSURE DEVICE AND METHODS FOR DETERMINING RF DOSE FOR PATENT FORAMEN OVALE CLOSURE 审中-公开
标题翻译：用于确定射频剂量的专利封闭式封闭装置和方法专利封闭式封闭装置
公开(公告)号：WO2007092860A3
公开(公告)日：2007-12-27
申请号：PCT/US2007061713
申请日：2007-02-06
申请人： COHEREX MEDICAL INC , WHISENANT BRIAN K , DAVIS CLARK C , MILES SCOTT D , LINDER RICHARD J , EDMISTON DARYL R
发明人： WHISENANT BRIAN K , DAVIS CLARK C , MILES SCOTT D , LINDER RICHARD J , EDMISTON DARYL R
IPC分类号： A61B5/04 , A61F2/00
CPC分类号： A61B5/053
摘要： A medical system and device for use in delivering RF energy to a tissue opening and a method for determining an RP dose is disclosed. In one embodiment, the medical device includes an electrode or anchor and one or more devices, such as an impedance electrode, RF electrode and/or thermocouple. The electrode or anchor can be deployed from a delivery shaft inside the left atrium, for example, of a heart and substantially conform to the tissue proximate the tissue opening. Tissue characteristics, such as temperature and/or impedance, can be measured, before, during and after application of RF energy to the tissue, by one or more devices to determine an RF dose. After energy is applied to the tissue between the left and right electrodes, the left electrode can be removed from the left atrium by being received back into the delivery shaft and the delivery shaft thereafter removed from the opening.
摘要翻译：公开了用于将RF能量递送至组织开口的医疗系统和装置以及用于确定RP剂量的方法。在一个实施例中，医疗装置包括电极或锚以及一个或多个装置，例如阻抗电极，RF电极和/或热电偶。电极或锚可以从例如心脏的左心房内的输送轴部署并且基本上贴合组织开口附近的组织。可以在通过一个或多个装置将RF能量施加到组织之前，期间和之后测量组织特性，例如温度和/或阻抗，以确定RF剂量。在向左右电极之间的组织施加能量之后，左电极可以通过被接收回到输送轴中而从左心房移除，并且随后从开口移除递送轴。

10. 发明申请

WO2007140419A2 METHODS, SYSTEMS, AND DEVICES FOR SENSING, MEASURING, AND CONTROLLING CLOSURE OF A PATENT FORAMEN OVALE 审中-公开
标题翻译：用于传感，测量和控制专利的封闭的方法，系统和装置
公开(公告)号：WO2007140419A2
公开(公告)日：2007-12-06
申请号：PCT/US2007/069994
申请日：2007-05-30
申请人： COHEREX MEDICAL, INC. , FOX, Dewayne, C. , EDMISTON, Daryl, R. , MILES, Scott, D. , DAVIS, Clark, C. , WHISENANT, Brian, K.
发明人： FOX, Dewayne, C. , EDMISTON, Daryl, R. , MILES, Scott, D. , DAVIS, Clark, C. , WHISENANT, Brian, K.
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B18/1492 , A61B2017/00026 , A61B2017/00084 , A61B2017/00575 , A61B2017/00623 , A61B2017/00867 , A61B2018/00791 , A61B2018/00875 , A61B2090/378
摘要： A medical device for reducing the size of a Patent Foramen Ovale is disclosed. The medical device can include a first electrode, a second electrode, and at least one sensor mounted to at least one of the first electrode or the second electrode, the at least one sensor adapted to sense at least one operating parameter of the medical device or the patient to facilitate closure of the Patent Foramen Ovale. The medical device can also include a delivery shaft coupled to the first electrode, wherein the delivery shaft includes an indicia for determining the position of the first electrode relative to the second electrode. A method for determining a characteristic of an internal tissue opening is also disclosed. The method can include the steps of introducing a detectable fluid in the right atrium of a heart and then detecting the location of the detectable fluid in the heart.
摘要翻译：公开了一种用于减小专利孔径的医疗装置。医疗装置可以包括第一电极，第二电极和安装到第一电极或第二电极中的至少一个的至少一个传感器，所述至少一个传感器适于感测医疗装置的至少一个操作参数或患者便利关闭专利孔卵巢。医疗装置还可以包括联接到第一电极的输送轴，其中输送轴包括用于确定第一电极相对于第二电极的位置的标记。还公开了一种用于确定内部组织开口的特性的方法。该方法可以包括在心脏的右心房中引入可检测流体，然后检测心脏中可检测流体的位置的步骤。

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