专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

61. 发明申请

WO2006089389A1 DIAPHRAGM-SEALED VALVE, ANALYTICAL CHROMATOGRAPHIC SYSTEM AND METHOD USING THE SAME 审中-公开
标题翻译：隔膜密封阀，分析色谱系统及其使用方法
公开(公告)号：WO2006089389A1
公开(公告)日：2006-08-31
申请号：PCT/CA2005/000236
申请日：2005-02-22
申请人： 9134-1859 QUEBEC INC. , GAMACHE, Yves , FORTIER, André
发明人： GAMACHE, Yves , FORTIER, André
IPC分类号： F16K7/16 , F16K11/22 , G01N30/20 , G01N30/24
CPC分类号： G01N30/20 , F16K11/022 , F16K11/20 , F16K31/06 , G01N30/468 , G01N2030/205
摘要： There is provided a diaphragm sealed valve particularly advantageous in chromatographic systems. The valve is provided with first and second body and a seal member compressibly positioned therebetween. The first body comprises a first, a second and a common port, each opening and being interconnected to the others in a recessed fluid communication channel extending in a first interface of the first body. The valve is also provided with first and second plungers, each having a closed position wherein the plunger presses down the seal member against the seat of the corresponding port for closing said corresponding port, and an open position wherein the plunger extends away from the seat for allowing a fluid communication between the corresponding port and the channel. Complex valves are also provided as well as chromatographic systems and methods.
摘要翻译：提供了一种在色谱系统中特别有利的隔膜密封阀。阀设置有第一和第二主体以及可压缩地定位在其间的密封构件。第一主体包括第一，第二和公共端口，每个开口并在与第一主体的第一界面中延伸的凹进的流体连通通道中互相连接。阀还设置有第一和第二柱塞，每个具有关闭位置，其中柱塞将密封构件压靠在相应端口的座上以关闭所述相应的端口，以及打开位置，其中柱塞远离座椅延伸，允许相应端口和通道之间的流体通信。还提供复杂的阀门以及色谱系统和方法。

62. 发明申请

WO2006029017A1 SYSTEM AND METHOD FOR RAPID CHROMATOGRAPHY WITH FLUID TEMPERATURE AND MOBILE PHASE COMPOSITION CONTROL 审中-公开
标题翻译：具有流体温度和移动相组成控制的快速色谱的系统和方法
公开(公告)号：WO2006029017A1
公开(公告)日：2006-03-16
申请号：PCT/US2005/031417
申请日：2005-09-02
申请人： SYMYX TECHNOLOGIES, INC. , PETRO, Miroslav , DIAMOND, Gary, M. , McWAID, Thomas, Harding , HALL, Keith, Anthony , LI, Song , TREVOR G., Frank
发明人： PETRO, Miroslav , DIAMOND, Gary, M. , McWAID, Thomas, Harding , HALL, Keith, Anthony , LI, Song , TREVOR G., Frank
IPC分类号： G01N30/20 , G01N30/28 , B01D15/14 , B01D15/12
CPC分类号： G01N30/30 , B01D15/161 , B01D15/166 , G01N30/20 , G01N30/28 , G01N30/32 , G01N30/34 , G01N30/80
摘要： The invention relates to liquid chromatography techniques for rapidly characterizing samples, such as polymer solutions, emulsions and dispersions, and to devices for implementing such techniques. The system includes a design that provides the ability to perform chromatographic separations by using mobile phase composition gradients and temperature gradients during separations. The invention accomplishes this by providing mixing zones for a plurality of fluids as well as heated and chilled feeds feeding the fluids to the mixing zones. Additionally, the system provides the ability to analyze separated components with a detector and/or collect separated fractions into vessels of a fraction collector for further separation and/or analysis.
摘要翻译：本发明涉及用于快速表征样品的液相色谱技术，例如聚合物溶液，乳液和分散体，以及用于实施这些技术的装置。该系统包括通过在分离期间使用流动相组成梯度和温度梯度提供进行色谱分离的能力的设计。本发明通过为多种流体提供混合区域以及将流体供给到混合区域的加热和冷冻进料来实现。此外，该系统提供了利用检测器分析分离的组分和/或将分离的馏分收集到馏分收集器的容器中用于进一步分离和/或分析的能力。

63. 发明申请

WO2005017491A3 LOOP DILUTION SYSTEM 审中-公开
标题翻译：循环稀释系统
公开(公告)号：WO2005017491A3
公开(公告)日：2005-06-09
申请号：PCT/US2004026303
申请日：2004-08-13
申请人： METARA INC , ANDERSON MARC R , WEST MICHAEL J , TAPPAN JAMES
发明人： ANDERSON MARC R , WEST MICHAEL J , TAPPAN JAMES
IPC分类号： B01L99/00 , G01N1/00 , G01N30/20 , G01N30/24 , B01L11/00 , G01N33/00
CPC分类号： G01N35/1097 , G01N30/24 , G01N2030/201 , G01N2030/202 , Y10T436/24
摘要： A loop dilution system (Figure 2a) includes a dual-loop multi-way valve (200). In a first configuration of the multi-way valve, a first loop (210) may be filled with a first solution and a second loop (205) may be filled with a second solution. In a second configuration of the multi-way valve, the first and second loops are serially connected with a pump so that their contents may be mixed with a diluent. In another aspect of the invention, an in-process mass spectrometry (IPMS) system is disclosed that uses an internal standard to determine the concentration of an analyte in a sample. The internal standard has a different molecular composition than the analyte but is sufficiently similar chemically and physically to the analyte such that it behaves substantially the same as the analyte during an ionization process in the mass spectrometer
摘要翻译：循环稀释系统（图2a）包括双回路多通阀（200）。在多通阀的第一构造中，可以用第一溶液填充第一回路（210），并且可以用第二溶液填充第二回路（205）。在多通阀的第二配置中，第一和第二回路与泵串联连接，使得它们的内容物可以与稀释剂混合。在本发明的另一方面，公开了一种使用内部标准来确定样品中分析物的浓度的过程中质谱（IPMS）系统。内标与分析物具有不同的分子组成，但与分析物的化学和物理性质充分相似，使得其在质谱仪中的离子化过程中与分析物基本相同

64. 发明申请

WO2005047826A2 A DEVICE AND METHOD FOR CONTROLLING THE FLOW OF FLUID IN A CONDUIT 审中-公开
标题翻译：用于控制流体中流体流动的装置和方法
公开(公告)号：WO2005047826A2
公开(公告)日：2005-05-26
申请号：PCT/US2004037640
申请日：2004-11-10
申请人： WATERS INVESTMENTS LTD , KEENE RUSSELL , MOELLER MARK , CIOLKOSZ THEODORE
发明人： KEENE RUSSELL , MOELLER MARK , CIOLKOSZ THEODORE
IPC分类号： F16K11/07 , G01F20060101 , G01N30/20 , G01N30/32 , G01N30/36 , G01F
CPC分类号： G01N30/36 , F16K11/07 , F16K41/043 , G01N2030/202 , G01N2030/328 , Y10T137/8242 , Y10T137/86501 , Y10T137/86863
摘要： The present invention provides devices and methods for controlling the flow of fluids in very high pressure situations. The devices feature valve shafts having bearings and pins to hold stator surfaces and rotor surfaces in proper alignment.
摘要翻译：本发明提供用于控制在非常高压力情况下的流体流动的装置和方法。这些装置具有带有轴承和销的阀轴，用于保持定子表面和转子表面的正确对准。

65. 发明申请

WO0146687A3 SYSTEM AND METHOD FOR AUTOMATED MATCHED ION POLYNUCLEOTIDE CHROMATOGRAPHY 审中-公开
标题翻译：自动匹配离子多核苷酸色谱的系统和方法
公开(公告)号：WO0146687A3
公开(公告)日：2003-04-17
申请号：PCT/US0029387
申请日：2000-10-25
申请人： TRANSGENOMIC INC
发明人： GJERDE DOUGLAS T , TAYLOR PAUL D
IPC分类号： G01N33/50 , B01D15/16 , B01D15/36 , B01J20/281 , B01J20/285 , C12N15/10 , C12Q1/68 , G01N30/04 , G01N30/20 , G01N30/24 , G01N30/26 , G01N30/30 , G01N30/32 , G01N30/34 , G01N30/54 , G01N30/74 , G01N30/80 , G01N30/82 , G01N30/86 , G01N30/88 , G01N30/96 , B01D15/08
CPC分类号： C12N15/101 , B01D15/166 , B01D15/366 , C12Q1/6869 , G01N30/30 , G01N30/96 , G01N2030/8827 , C12Q2565/137 , C12Q2527/107
摘要： In an extensive Matched Ion Polynucleotide Chromatography (MIPC) system and method, and the computer programs or software associated therewith, the system provides automated options for sample selection, mobile phase gradient selection and control, column and mobile phase temperature control, and fragment collection for a wide variety of MIPC separation processes. MIPC separation processes can be applied to effect size-based separation of DNA fragments, mutation detection, DNA fragment purification, PCR process monitoring and other novel processes. This invention is directed to the system and software which automates many of these procedures, facilitating use of the system to achieve complex separation methods. In one embodiment of the invention, a user specifies a size range of double stranded DNA fragment(s) in a mixture, the software calculates a solvent gradient to elute the fragment(s), and the system performs the chromatographic separation using the calculated gradient. In an embodiment useful in DNA mutation detection, a user specifies the base sequence of a wild type DNA molecule, the software calculates a temperature for partially denaturing heteroduplex and homoduplex molecules of the DNA in a mixture, the software calculates a solvent gradient to elute the fragments, and the system performs the chromatographic separation using the calculated gradient and temperature.
摘要翻译：在广泛的匹配离子多核苷酸色谱（MIPC）系统和方法以及与其相关的计算机程序或软件中，系统提供用于样品选择，流动相梯度选择和控制，色谱柱和流动相温度控制以及片段收集的自动选择各种MIPC分离过程。可以应用MIPC分离过程来实现基于大小的DNA片段分离，突变检测，DNA片段纯化，PCR过程监控等新方法。本发明涉及自动化许多这些程序的系统和软件，便于使用该系统来实现复杂的分离方法。在本发明的一个实施方案中，用户指定混合物中双链DNA片段的大小范围，软件计算溶剂梯度以洗脱片段，并且系统使用计算的梯度进行色谱分离。在DNA突变检测中有用的实施方案中，用户指定野生型DNA分子的碱基序列，软件计算混合物中DNA的部分变性异源双链体和同源双链体分子的温度，软件计算溶剂梯度洗脱片段，系统使用计算的梯度和温度进行色谱分离。

66. 发明申请

WO02039105A1 SAMPLE INJECTION VALVE FOR HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC) DEVICES 审中-公开
标题翻译：示例任务阀用于HPLC设备
公开(公告)号：WO02039105A1
公开(公告)日：2002-05-16
申请号：PCT/CH2001/000661
申请日：2001-11-12
IPC分类号： G01N35/10 , G01N30/20 , G01N30/24
CPC分类号： G01N30/20 , G01N30/24 , G01N2030/201 , G01N2030/202 , Y10T137/86743 , G01N2030/402
摘要： The sample injection valve for high-performance liquid chromatography (HPLC) devices comprises a stator with inlets for the sample and the mobile phase, outlets leading to the chromatography column and to a waste collector, as well as connections for both ends of a sample loop. Its rotor has the customary connection channels. An additional washing liquid inlet (7) opens into the connecting channel (9) that, in one valve position, connects the sample inlet (1) to the outlet (2) leading to the waste collector. This enables the sample inlet and the pipette or syringe located therein to be rinsed.
摘要翻译：样本喷射阀具有用于样品输入和流动相，输出到层析柱并至废物收集器，以及连接于进样环的两个端部的定子HPLC设备。其转子具有通常的通信信道。额外的洗涤液入口（7）通入所述样品输入的在阀位置（1）到输出端（2），用于废物收集器连接的连接通道（9）。这允许样品入口和在其内的移液管或注射器的冲洗。

67. 发明申请

WO02012878A1 HPLC VALVE 审中-公开
公开(公告)号：WO02012878A1
公开(公告)日：2002-02-14
申请号：PCT/CH2000/000531
申请日：2000-09-29
IPC分类号： G01N30/20
CPC分类号： G01N30/20 , G01N2030/202
摘要： The HPLC valve (1) comprises a rotor (11) with connector channels (12, 13) which connect together not just the usual two, but three connections on the stator (10) in particular rotor positions. A pressure equalisation is thus possible during the rotor turning, as well as further functions being possible.
摘要翻译： HPLC的阀（1）具有转子（11）与连接在一定的转子位置，连接通道（12,13）不仅像往常一样，两个，而是三个端子在定子（10）彼此连接。转子旋转过程中，该压力平衡等功能是可能的。

68. 发明申请

WO0155714A8 METHOD AND APPARATUS FOR CONCENTRATING SAMPLES FOR ANALYSIS 审中-公开
标题翻译：浓缩样品分析方法与装置
公开(公告)号：WO0155714A8
公开(公告)日：2002-02-07
申请号：PCT/US0102607
申请日：2001-01-25
申请人： OREGON STATE , BRIEN ROBERT J JR O
发明人： O'BRIEN ROBERT J JR
IPC分类号： G01N33/497 , G01N1/00 , G01N1/02 , G01N1/22 , G01N1/24 , G01N1/36 , G01N1/40 , G01N15/00 , G01N21/27 , G01N21/33 , G01N21/35 , G01N30/02 , G01N30/04 , G01N30/06 , G01N30/08 , G01N30/20 , G01N30/22 , G01N30/32 , G01N30/34 , G01N30/46 , G01N30/62 , G01N30/64 , G01N30/68 , G01N30/70 , G01N30/74 , G01N30/78 , G01N30/86 , G01N30/88 , G01N33/00 , G01W1/17 , B01D15/00 , G01M19/00 , G01N25/00
CPC分类号： G01N1/2202 , G01N1/24 , G01N1/40 , G01N30/06 , G01N30/22 , G01N30/78 , G01N30/8606 , G01N30/8641 , G01N2001/2223 , G01N2001/4027 , G01N2015/0046 , G01N2015/0092 , G01N2030/025 , G01N2030/328 , G01N2030/625 , G01N2030/626 , G01N30/32
摘要： A method for analyzing a gas sample is described (10). The method comprises providing a gas sample, increasing pressure applied to the gas sample to compress the sample to a smaller volume and provide a pneumatically focused gas sample, and analyzing the pneumatically focused gas sample using any of a variety of analytical techniques. Pneumatic Focusing generally means increasing the pressure of the sample, column or cell to a pressure of from about 100 psi to about 15,000 psi, more typically from about 200 psi to about 2,000 psi. Examples including gas chromatography and absorption spectroscopy are illustrated herein. Numerous other examples could be given. The method is well suited for analyzing gaseous samples, such as ambient air samples, both continuously, and remotely, using computer control. Continuously sampling ambient air provides a method for real-time monitoring of air quality. Continuous monitoring (58) allows for pollutant exposure and allows for the identification of emission sources. The method is also well suited for analysis of breath exhalations from respiring organisms useful in metabolic studies or disease diagnosis.
摘要翻译：（10）描述气体样品分析方法。该方法包括提供气体样品，增加施加到气体样品的压力以将样品压缩到更小的体积并提供气动聚焦的气体样品，以及使用各种分析技术中的任何一种分析气动聚焦的气体样品。气动聚焦通常意味着将样品，柱或细胞的压力提高到约100psi至约15,000psi，更典型地约200psi至约2,000psi的压力。本文说明了包括气相色谱和吸收光谱的实例。可以给出很多其他例子。该方法非常适用于使用计算机控制连续和远程分析气态样品，如环境空气样品。连续采样环境空气提供了一种实时监测空气质量的方法。持续监测（58）允许污染物暴露并允许识别排放源。该方法也非常适用于分析代谢研究或疾病诊断中有用的呼吸生物的呼吸呼气。

69. 发明申请

WO00011462A1 METHOD AND DEVICE FOR DRAWING MICRO-SAMPLES OF PRESSURISED FLUID CONTAINED IN A CONTAINER 审中-公开
标题翻译：用于绘制集装箱中包含的加压流体的微型样品的方法和装置
公开(公告)号：WO00011462A1
公开(公告)日：2000-03-02
申请号：PCT/FR1999/002015
申请日：1999-08-19
IPC分类号： G01N1/20 , G01N30/20 , G01N30/22 , G01N30/60
CPC分类号： G01N30/20 , G01N30/22 , G01N2001/205 , G01N2030/6008
摘要： The invention concerns a method and a device for drawing micro-samples of a pressurised fluid contained in a container (1), for analysis of said samples, in particular by chromatography. The method comprises steps which consist in: communicating a container (1) containing the pressurised fluid to be sampled with a transfer circuit (6) traversed by a driving fluid, through a capillary orifice (4) located at the capillary tube (5) end; opening and closing said capillary orifice (4) using a mobile lock piston (7); actuating said lock piston (7) by deforming an extensible chamber (8) containing said mobile lock piston (7) sealed. Thus, the tightness around said mobile lock piston is ensured without requiring a sliding fluid seal.
摘要翻译：本发明涉及一种用于抽取包含在容器（1）中的加压流体的微样品的方法和装置，用于分析所述样品，特别是通过色谱法。该方法包括以下步骤：将包含被采样的加压流体的容器（1）与由驱动流体穿过的传送回路（6）通过位于毛细管（5）端部的毛细孔（4）连通 ; 使用移动锁定活塞（7）打开和关闭所述毛细管孔（4）; 通过使包含所述可移动锁定活塞（7）的可伸展室（8）变形来致动所述锁定活塞（7）。因此，确保了所述移动锁定活塞周围的紧密度，而不需要滑动流体密封。

70. 发明申请

WO1995027199A1 CHROMATOGRAPHY SYSTEM AND METHODOLOGY 审中-公开
标题翻译：色谱系统和方法学
公开(公告)号：WO1995027199A1
公开(公告)日：1995-10-12
申请号：PCT/GB1995000693
申请日：1995-03-28
申请人： HJELM, Nils, Magnus
IPC分类号： G01N30/20
CPC分类号： G01N30/34 , B01L3/5023 , G01N30/20 , G01N30/6091 , G01N35/1097 , G01N2030/204 , G01N2030/207 , G01N2030/326 , G01N2030/8417
摘要： A liquid chromatography system comprises a chromatographic disc (4) for resolving molecules in a liquid sample, a sample loader (2) adapted to house the disc (4), the loader (2) having one or more storage channels (16) for taking up a predetermined volume of the sample by capillary action and delivering it to the disc (4) and means (18) for delivering a buffer and/or eluent to the disc. The sample loader (2) may comprise a body portion (6) acting as a housing for the disc (4), and having (i) a loading channel (8) for conducting liquid onto or through the disc (4), comprising an afferent portion having an inlet (10) for conducting liquid to the disc (4) and an afferent portion having an outlet (12) for conducting liquid away from the disc, and (ii) a selector element (14) (e.g. a rotatable disc or a slideable bar) movably mounted on the body portion (6) so as to break the afferent portion of the loading channel (8).
摘要翻译：液相色谱系统包括用于分解液体样品中的分子的色谱盘（4），适于容纳盘（4）的样品装载器（2），装载器（2）具有一个或多个存储通道（16）通过毛细作用提取样品的预定体积并将其递送到盘（4）和用于将缓冲液和/或洗脱液输送到盘的装置（18）。样品装载器（2）可以包括用作盘（4）的壳体的主体部分（6），并且具有（i）用于将液体导入或通过盘（4）的装载通道（8），包括传入部分具有用于将液体引导到盘（4）的入口（10）和具有用于将液体远离盘的出口（12）的传入部分，以及（ii）选择器元件（14）（例如旋转盘或可滑动杆）可移动地安装在主体部分（6）上，以便打破装载通道（8）的传入部分。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式