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61. 发明申请

WO2007149404A3 SELF-CLEANING STENT 审中-公开
标题翻译：自清洁手套
公开(公告)号：WO2007149404A3
公开(公告)日：2008-02-14
申请号：PCT/US2007014214
申请日：2007-06-18
申请人： WILSON COOK MEDICAL INC , CARTER MATTHEW P , JONES BRIAN K
发明人： CARTER MATTHEW P , JONES BRIAN K
IPC分类号： A61B17/22 , A61F2/82
CPC分类号： A61F2/82 , A61B17/22 , A61B2017/320004 , A61B2017/320012
摘要： A stent (10) is provided that is able to resist clogging from cumulative matter found within a fluid that passes therethrough. The stent includes a mass (13) moveably disposed therein, wherein movement of the stent tends to dislodge any cumulative matter accumulated within the stent. As a result, the device is able to remain resident within the patient for an extended period of time before becoming clogged and needing to be replaced.
摘要翻译：提供了能够抵抗在通过其中的流体内发现的累积物质堵塞的支架（10）。支架包括可移动地设置在其中的质量块（13），其中支架的运动倾向于移除在支架内积累的任何累积物质。因此，该设备能够在被阻塞并且需要更换之前长时间地保持在患者体内。

62. 发明申请

WO2007149103A2 VASCULAR TISSUE ENHANCEMENT AND SELECTIVE DESTRUCTION OF CANCEROUS CELLULAR TISSUE 审中-公开
标题翻译：血管组织增强和选择性破坏癌细胞组织
公开(公告)号：WO2007149103A2
公开(公告)日：2007-12-27
申请号：PCT/US2006025443
申请日：2006-06-28
申请人： KAISER DANIEL E
发明人： KAISER DANIEL E
IPC分类号： A61B19/00
CPC分类号： A61H9/005 , A61B17/1128 , A61B17/22 , A61B17/2251 , A61B2017/00535 , A61B2017/00561 , A61B2017/00911 , A61B2017/22001 , A61H9/0057 , A61H2201/5082 , A61H2201/5087 , A61H2201/5089 , A61H2205/06 , A61H2205/083 , A61H2205/10
摘要： An apparatus for delivering decompressive energy to soft tissues to stimulate cellular expansion through deep penetration of said applied decompressive energy to said soft tissues to stimulate a predetermined reaction to application of said decompressive energy comprising a vessel having an open end and adapted to encompass the soft tissue to be stimulated. A source of decompressive energy in communication with said vessel and a flexible mass affixed to said open end of said vessel to absorb the pressure exerted by delivery of said decompressive energy to said soft tissue, thereby acting as a seal and force diffuser between said vessel and the soft tissue adjacent the periphery of said vessel. A method for the treatment of peripheral vascular disease (PVD) and other medical disorders and ailments that would benefit from increased and enhanced tissue response due to increases in blood flow on macro-vascular, micro-vascular and a collateral level including increased cellular stimulation and response. The method works by surrounding said tissues with a vessel or dome configured to fit over the tissue for treatment with decompressive energy (vacuum forces). The decompressive energy is applied in a controlled manner at a pre-selected level of decompressive force thereby increasing blood flow through the treated tissue. Loading forces generated by applied decompressive energy and the resulting forces generated between the interior of the vessel and the treated tissue which the vessel encompasses are diffused. A method and apparatus for applying decompressive energy to tissue for the selective destruction of cancerous cells is disclose and claimed. The tissue to be treated is enclosed within a vessel subjected to decompressive energy supplied by said decompressive energy source to said vessel. The decompressive energy is applied in a controlled manner to said tissue in at a pre-selected level of decompressive energy. Loading forces generated by applied decompressive energy and the forces generated between the interior of said vessel and said tissue which said vessel encompasses are to be diffused. As disclosed and claimed, a mass of elastic material comprising an inner radius and outer radius with the inner radius forming a seal with said tissue while allowing said tissue to move in relation to said inner radius and a fluid pocket circumf erentially positioned within said elastic mass in combination with a collar positioned at the perimeter of the vessel opening is claimed.
摘要翻译：一种用于向软组织递送减压能量以通过将所述施加的减压能量深入渗透到所述软组织来刺激细胞扩张的装置，以刺激施加所述减压能量的预定反应，所述减压能量包括具有开口端的容器并且适于包围软组织被刺激。与所述容器连通的减压能量源和固定在所述容器的所述开口端的柔性块，以吸收通过将所述减压能量递送到所述软组织而施加的压力，由此用作所述容器和所述软组织邻近所述容器的周边。一种用于治疗外周血管疾病（PVD）和其他医学疾病和疾病的方法，其将受益于由于血管，微血管和附属水平的血流增加而增加和增强的组织反应，包括增加的细胞刺激和响应。该方法通过用构造成适合于组织上的血管或圆顶围绕所述组织进行工作，以用减压能（真空力）进行治疗。减压能量以受控的方式以预选的减压力水平施加，从而增加经过处理的组织的血液流量。通过施加的减压能量产生的装载力和在容器内部和容器所包括的经处理的组织之间产生的所产生的力被扩散。公开并要求保护用于将选择性破坏癌细胞的减压能量应用于组织的方法和装置。要处理的组织被包封在经受由所述减压能源供应给所述容器的减压能量的容器内。减压能量以受控的方式以预先选择的减压能量水平施加到所述组织。通过施加的减压能量产生的装载力和在所述容器的内部和所述容器所包围的所述组织之间产生的力将被扩散。如所公开和要求保护的，包括内半径和外半径的弹性材料块，其中内半径与所述组织形成密封，同时允许所述组织相对于所述内半径移动，并且周向地定位在所述弹性质量块内的流体袋与位于容器开口的周边的套环组合。

63. 发明申请

WO2006121606A3 MINIMALLY INVASIVE APPARATUS AND METHOD FOR TREATMENT OF A TUMOR ASSOCIATED WITH A BONE 审中-公开
标题翻译：用于治疗与骨骼相关的肿瘤的微型入侵装置和方法
公开(公告)号：WO2006121606A3
公开(公告)日：2007-10-25
申请号：PCT/US2006015620
申请日：2006-04-26
申请人： KYPHON INC , PALMER ERIKA I
发明人： PALMER ERIKA I
IPC分类号： A61M31/00
CPC分类号： A61B10/025 , A61B10/0283 , A61B17/22 , A61B17/3421 , A61B17/3472 , A61B17/3478 , A61B2017/00261 , A61B2017/306 , A61B2017/3445 , A61B2090/3916 , A61B2090/3995 , A61B2217/005
摘要： A method includes percutaneously accessing a patient via a cannula, such that a distal end of the cannula is disposed substantially adjacent a tumor associated with a bone of the patient. A composition of the tumor is modified via a medical device movably disposed within the cannula. At least a portion of the tumor is removed through the cannula. The modifying is performed during a first time period and the removing is performed during a second time period. At least a portion of the first time period overlaps with at least a portion of the second time period.
摘要翻译：一种方法包括经由插管经皮访问患者，使得套管的远端基本上邻近于与患者的骨骼相关联的肿瘤。通过可移动地设置在套管内的医疗装置来改变肿瘤的组成。通过套管去除肿瘤的至少一部分。在第一时间段期间执行修改，并且在第二时间段期间执行删除。第一时间段的至少一部分与第二时间段的至少一部分重叠。

64. 发明申请

WO2006110773A3 ULTRASOUND CATHETER WITH CAVITATION PROMOTING SURFACE 审中-公开
标题翻译：超声波导管带孔加速表面
公开(公告)号：WO2006110773A3
公开(公告)日：2007-07-26
申请号：PCT/US2006013531
申请日：2006-04-12
申请人： EKOS CORP , SOLTANI AZITA , HANSMANN DOUGLAS R
发明人： SOLTANI AZITA , HANSMANN DOUGLAS R
IPC分类号： A61B8/14 , A61B17/20
CPC分类号： A61B17/22 , A61B17/2202 , A61B2017/00154 , A61B2017/22008 , A61B2017/22088 , A61M37/0092 , A61N7/00 , A61N2007/0039
摘要： In one embodiment of the present invention, a method of applying ultrasonic energy to a treatment site within a patient's vasculature comprises positioning an ultrasound radiating member at a treatment site within a patient's vasculature. The method further comprises activating the ultrasound radiating member to produce pulses of ultrasonic energy at a cycle period T = 1 second. Each pulse of ultrasonic energy has a first peak amplitude for a first duration, and a second reduced amplitude that is less than the first peak amplitude for a second duration.
摘要翻译：在本发明的一个实施例中，将超声波能量施加到患者脉管系统内的治疗部位的方法包括将超声波辐射构件定位在患者脉管系统内的治疗部位。该方法还包括激活超声辐射构件以在循环周期T = 1秒产生超声能量的脉冲。超声能量的每个脉冲具有第一持续时间的第一峰值幅度，以及在第二持续时间内小于第一峰值幅度的第二减小幅度。

65. 发明申请

WO2007038150A3 THROMBECTOMY CATHETER DEPLOYMENT SYSTEM 审中-公开
标题翻译：血栓导管部署系统
公开(公告)号：WO2007038150A3
公开(公告)日：2007-07-05
申请号：PCT/US2006036684
申请日：2006-09-21
申请人： POSSIS MEDICAL INC , THOR ERIC JOEL , BONNETTE MICHAEL JOHN , AASEN NICOLE JAYE , ABBOTT MARTYN STUART , BALL DOUGLAS JAMES , CROLL WALTER CHARLES , CUMMINGS DAVID CHARLES , GRANT CHAD NICHOLAS , HILSE MARK ALFRED , KARPINSKI JAMES FREDRICK , KNEIP DANIEL JOSEPH , ROGERS JEFFREY WILLIAM , SCHERGER ERNEST RALPH , TESCHENDORF JOHN LLOYD , WEISEL STEPHEN EARL , WEST DAVID WOODRUFF
发明人： THOR ERIC JOEL , BONNETTE MICHAEL JOHN , AASEN NICOLE JAYE , ABBOTT MARTYN STUART , BALL DOUGLAS JAMES , CROLL WALTER CHARLES , CUMMINGS DAVID CHARLES , GRANT CHAD NICHOLAS , HILSE MARK ALFRED , KARPINSKI JAMES FREDRICK , KNEIP DANIEL JOSEPH , ROGERS JEFFREY WILLIAM , SCHERGER ERNEST RALPH , TESCHENDORF JOHN LLOYD , WEISEL STEPHEN EARL , WEST DAVID WOODRUFF
IPC分类号： A61M5/00 , A61B9/00 , A61M29/00 , A61M37/00
CPC分类号： A61B17/22 , A61B17/32037 , A61B50/10 , A61B50/13 , A61M5/14216 , A61M5/14232 , A61M5/36 , A61M25/0122 , A61M2205/6018
摘要： A thrombectomy catheter deployment system which greatly simplifies setup procedures and operation of a thrombectomy catheter includes a stand alone drive unit and a disposable pump/catheter assembly which is manually placed into a carriage assembly in the drive unit. The pump/catheter assembly has a plurality of preconnected components including tubular structure and a thrombectomy catheter connected thereto and is transported into or out of the interior of the drive unit for automatic high pressure pump piston head engagement or disengagement with a reciprocating linear actuator and for automatic engagement or disengagement of an effluent waste tube with a roller pump. A barcode reader senses specific operational data pertaining to an individual pump and provides an interface for operation of the reciprocating linear actuator. A bubble trap incorporated for effective debubbling of saline solution is closely coupled to an insert molded pump having an improved valve arrangement.
摘要翻译：大大简化了血栓切除术导管的设置步骤和操作的血栓切除术导管展开系统包括一个独立的驱动单元和一个一次性的泵/导管组件，其被手动放置在驱动单元中的托架组件中。泵/导管组件具有多个预先连接的组件，包括管状结构和连接到其上的血栓切除术导管，并且被输送到驱动单元的内部或外部，用于自动高压泵活塞头与往复式线性致动器的接合或分离，并且废水管与滚筒泵的自动接合或分离。条形码读取器感测与单个泵相关的特定操作数据，并提供用于往复式线性致动器的操作的接口。结合用于盐溶液有效脱泡的气泡阱紧密耦合到具有改进的阀布置的插入式模制泵。

66. 发明申请

WO2007047368A9 CHANNELED ENDOMURAL THERAPY 审中-公开
标题翻译：通道内膜治疗
公开(公告)号：WO2007047368A9
公开(公告)日：2007-06-21
申请号：PCT/US2006039891
申请日：2006-10-13
申请人： ENDOLUMINAL THERAPEUTICS INC , SLEPIAN MARVIN J
发明人： SLEPIAN MARVIN J
IPC分类号： A61B17/22 , A61B17/00 , A61B17/88 , A61B18/24 , A61F2/958
CPC分类号： A61B17/3207 , A61B17/00491 , A61B17/12022 , A61B17/12186 , A61B17/1219 , A61B17/12195 , A61B17/22 , A61B18/24 , A61B2017/00247 , A61B2017/1205 , A61B2017/22077 , A61B2018/00392 , A61K35/545
摘要： Diseases, aging, trauma, environmental exposure, infection and other events or agents can alter tissue function. In one embodiment, treatment is provided by therapeutically altering tissue function. This may be by continuing normal tissue function, suppressing tissue function, or enhancing tissue function. In a preferred embodiment, this treatment is effectuated by penetrating an organ, organ component or tissue structure and placing a supplemental material in a newly created space. This space is generally referred to herein as a "privileged space", i.e. a space not otherwise present in native tissue. Supplemental materials can be deposited and secured within the zone. Supplemental materials include materials forming barriers, supports, and/or materials that deliver agents having a pharmacologic, biochemical, or physiologic effect in vivo. Suitable supplemental materials include polymeric and non-polymeric materials, pharmacologic agents, cells, tissue fragments, microorganisms, viral agents, or other reagents modifying tissue function. The supplemental material is typically in the form of a reservoir/depot, or continuous or discontinuous layer. In one embodiment, supplemental materials, and methods of use thereof, are provided for the continuous or discontinuous therapy of defined regions of an organ, organ component or tissue structure. The supplemental materials may be delivered directly to any one or more of the three zones, endoluminal (or ectomural, for solid organs), endomural, or ectoluminal, of organs, organ components, or tissue structures. The supplemental materials can include natural or synthetic polymeric materials that are biodegradable or non-biodegradable. The supplemental materials can also contain bioactive agents to effectuate a change in an organ or organ component in need thereof. For example, agents that result in a reduced/hyponormal response or an amplified/hypernormal response may be included in the supplemental materials.
摘要翻译：疾病，老化，创伤，环境暴露，感染等事件或药剂可改变组织功能。在一个实施方案中，通过治疗性改变组织功能来提供治疗。这可能是通过持续正常的组织功能，抑制组织功能或增强组织功能。在优选的实施方案中，通过穿透器官，器官组分或组织结构并将补充材料放置在新创建的空间中来实现该治疗。该空间在本文中通常被称为“特权空间”，即在天然组织中不存在的空间。补充材料可以在区域内沉积并固定。补充材料包括形成屏障，载体和/或递送在体内具有药理学，生物化学或生理学作用的物质的材料。合适的补充材料包括聚合物和非聚合材料，药理学试剂，细胞，组织碎片，微生物，病毒试剂或修饰组织功能的其他试剂。补充材料通常是储存器/储存器或连续或不连续层的形式。在一个实施方案中，提供补充材料及其使用方法用于器官，器官组分或组织结构的限定区域的连续或不连续治疗。补充材料可以直接递送到器官，器官成分或组织结构的内腔（或体外，对于固体器官），内膜或体腔内的三个区域中的任何一个或多个。补充材料可以包括可生物降解或不可生物降解的天然或合成聚合材料。补充材料还可以含有生物活性剂以实现有需要的器官或器官成分的变化。例如，可以在补充材料中包括导致减少/低反应或者放大/超正常反应的药剂。

67. 发明申请

WO2006007410A3 MINIMALLY INVASIVE CORING VEIN HARVESTER 审中-公开
标题翻译：最小的入侵角钢收割机
公开(公告)号：WO2006007410A3
公开(公告)日：2007-04-19
申请号：PCT/US2005021361
申请日：2005-06-16
申请人： MEDTRONIC INC , BONNER MATTHEW D , KEOGH JAMES R , BRISCOE RODERICK E , JOLLY KATHERINE S , USHER RAYMOND W , BUHR REBECCA A , CHRISTIAN STEVEN C , CLAGUE CYNTHIA T , HOBDAY MICHAEL J , JAHNS SCOTT E , HAARSTAD PHILIP J , DAIGLE TOM P , REETZ ROBERT H , SANDSTROM JEFFREY D
发明人： BRISCOE RODERICK E , JOLLY KATHERINE S , USHER RAYMOND W , BUHR REBECCA A , CHRISTIAN STEVEN C , CLAGUE CYNTHIA T , HOBDAY MICHAEL J , JAHNS SCOTT E , HAARSTAD PHILIP J , DAIGLE TOM P , REETZ ROBERT H , SANDSTROM JEFFREY D
IPC分类号： A61B17/00
CPC分类号： A61B17/22 , A61B17/00008 , A61B17/320016 , A61B17/32002 , A61B17/32053 , A61B2017/00557 , A61B2017/00778 , A61B2017/22062 , A61B2017/22068
摘要： The invention provides a system and method for harvesting a vessel section. The system comprises a vessel support member, a handle, and a tubular cutting device. The vessel support member is introduced into the vessel section to be harvested. The tubular cutting device may comprise an outer tubular member or an outer and an inner tubular member. The outer tubular member carries at least one cutting element. The tubular member or members are advanced over the vessel section and vessel support member to core out the vessel section and tissue adjoining the vessel section.
摘要翻译：本发明提供了一种收集血管部分的系统和方法。该系统包括容器支撑构件，手柄和管状切割装置。将容器支撑构件引入待收获的容器部分。管状切割装置可以包括外部管状构件或外部管状构件和内部管状构件。外部管状构件承载至少一个切割元件。管状构件在容器部分和容器支撑构件上前进，以将与容器部分相邻的容器部分和组织芯出。

68. 发明申请

WO2007038150A2 THROMBECTOMY CATHETER DEPLOYMENT SYSTEM 审中-公开
标题翻译：血栓导管部署系统
公开(公告)号：WO2007038150A2
公开(公告)日：2007-04-05
申请号：PCT/US2006/036684
申请日：2006-09-21
申请人： POSSIS MEDICAL, INC. , THOR, Eric, Joel , BONNETTE, Michael, John , AASEN, Nicole, Jaye , ABBOTT, Martyn, Stuart , BALL, Douglas, James , CROLL, Walter, Charles , CUMMINGS, David, Charles , GRANT, Chad, Nicholas , HILSE, Mark, Alfred , KARPINSKI, James, Fredrick , KNEIP, Daniel, Joseph , ROGERS, Jeffrey, William , SCHERGER, Ernest, Ralph , TESCHENDORF, John, Lloyd , WEISEL, Stephen, Earl , WEST, David, Woodruff
发明人： THOR, Eric, Joel , BONNETTE, Michael, John , AASEN, Nicole, Jaye , ABBOTT, Martyn, Stuart , BALL, Douglas, James , CROLL, Walter, Charles , CUMMINGS, David, Charles , GRANT, Chad, Nicholas , HILSE, Mark, Alfred , KARPINSKI, James, Fredrick , KNEIP, Daniel, Joseph , ROGERS, Jeffrey, William , SCHERGER, Ernest, Ralph , TESCHENDORF, John, Lloyd , WEISEL, Stephen, Earl , WEST, David, Woodruff
IPC分类号： A61M1/00
CPC分类号： A61B17/22 , A61B17/32037 , A61B50/10 , A61B50/13 , A61M5/14216 , A61M5/14232 , A61M5/36 , A61M25/0122 , A61M2205/6018
摘要： A thrombectomy catheter deployment system which greatly simplifies setup procedures and operation of a thrombectomy catheter includes a stand alone drive unit and a disposable pump/ catheter assembly which is manually placed into a carriage assembly in the drive unit. The pump/catheter assembly has a plurality of preconnected components including tubular structure and a thrombectomy catheter connected thereto and is transported into or out of the interior of the drive unit for automatic high pressure pump piston head engagement or disengagement with a reciprocating linear actuator and for automatic engagement or disengagement of an effluent waste tube with a roller pump. A barcode reader senses specific operational data pertaining to an individual pump and provides an interface for operation of the reciprocating linear actuator. A bubble trap incorporated for effective debubbling of saline solution is closely coupled to an insert molded pump having an improved valve arrangement. A spiked bag with large tubing is incorporated for bubble-free transfer of saline.
摘要翻译：大大简化了血栓切除术导管的设置步骤和操作的血栓切除术导管展开系统包括一个独立的驱动单元和一个一次性的泵/导管组件，其被手动放置在驱动单元中的托架组件中。泵/导管组件具有多个预先连接的组件，包括管状结构和连接到其上的血栓切除术导管，并被输送到驱动单元的内部或外部，用于自动高压泵活塞头与往复式线性致动器的接合或分离，并且废水管与滚筒泵的自动接合或分离。条形码读取器感测与单个泵相关的特定操作数据，并提供用于往复式线性致动器的操作的接口。结合用于盐溶液有效脱泡的气泡阱紧密耦合到具有改进的阀布置的插入式模制泵。掺有大管的加注袋用于无气泡转移盐水。

69. 发明申请

WO2006119009A1 NON-LITHOTRIPSIC KIDNEY-STONE THERAPY 审中-公开
标题翻译：非理想KIDNEY-STONE治疗
公开(公告)号：WO2006119009A1
公开(公告)日：2006-11-09
申请号：PCT/US2006/016208
申请日：2006-04-27
申请人： PLUROMED, INC. , MCDOUGAL, W., Scott , SACCO, Dianne, E. , SCHWARZ, Alexander , VOGEL, Jean-Marie
发明人： MCDOUGAL, W., Scott , SACCO, Dianne, E. , SCHWARZ, Alexander , VOGEL, Jean-Marie
IPC分类号： A61K47/10 , A61K47/36 , A61K9/00
CPC分类号： A61B17/22 , A61B17/32056 , A61B2017/00818 , A61B2017/00849 , A61B2017/00853 , A61B2017/22037 , A61B2017/22082 , A61B2018/005 , A61B2018/00511 , A61K9/0019 , A61K47/10 , A61K47/36 , A61K49/0002 , A61L24/001 , A61L24/046 , A61L2400/06 , C08L71/02
摘要： One aspect of the present invention relates to a method of using peristalsis to force a polymer plug through a mammalian lumen, thereby removing any calculi and/or calculi fragments present in the lumen. In one embodiment, the method is used as an alternative to conventional lithotripsy. In another embodiment, the method is used in conjunction with lithotripsy, thereby removing the small calculi fragments that result from such procedures.
摘要翻译：本发明的一个方面涉及使用蠕动来迫使聚合物塞通过哺乳动物腔，从而去除内腔中存在的任何结石和/或结石碎片的方法。在一个实施例中，该方法用作常规碎石术的替代方案。在另一个实施方案中，该方法与碎石结合使用，从而去除由此类程序产生的小结石碎片。

70. 发明申请

WO2006115693A2 METHOD AND APPARATUS FOR PACING DURING REVASCULARIZATION 审中-公开
标题翻译：用于在重新血液化期间起搏的方法和设备
公开(公告)号：WO2006115693A2
公开(公告)日：2006-11-02
申请号：PCT/US2006011972
申请日：2006-03-30
申请人： CARDIAC PACEMAKERS INC , SHUROS ALLAN , BAYNHAM TAMARA COLETTE , QU JIHONG , PASTORE JOSEPH M , KRAMER ANDREW P , PRINZEN FRITS W , VANAGT WARD Y R , CORNELUSSEN RICHARD N
发明人： SHUROS ALLAN , BAYNHAM TAMARA COLETTE , QU JIHONG , PASTORE JOSEPH M , KRAMER ANDREW P , PRINZEN FRITS W , VANAGT WARD Y R , CORNELUSSEN RICHARD N
IPC分类号： A61N1/37 , A61B18/14 , A61M25/00
CPC分类号： A61N1/362 , A61B17/22 , A61B18/1492 , A61B2017/22001 , A61B2018/00214 , A61B2018/0041 , A61B2018/00422 , A61N1/056 , A61N1/3625 , A61N5/1001 , A61N2001/0585
摘要： Cardiac protection pacing is applied to prevent or reduce cardiac injury and/or occurrences of arrhythmia associated with an ischemic event including the occlusion of a blood vessel during a revascularization procedure. Pacing pulses are generated from a pacemaker and delivered through one or more pacing electrodes incorporated onto a percutaneous transluminal vascular intervention (PTVI) device used in the revascularization procedure. The pacemaker generates the pacing pulses according to a predetermined cardiac protection pacing sequence before, during, and/or after the ischemic event.
摘要翻译：应用心脏保护起搏以预防或减少心脏损伤和/或与缺血事件相关的心律失常的发生，所述缺血事件包括血管重建术过程中血管的闭塞。起搏脉冲由心脏起搏器产生并通过一个或多个起搏电极输入，所述起搏电极结合到血管再通术中使用的经皮腔内血管介入（PTVI）装置上。起搏器根据预先确定的心脏保护起搏序列在缺血事件之前，期间和/或之后产生起搏脉冲。

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