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1. 发明申请

WO2006115693A2 METHOD AND APPARATUS FOR PACING DURING REVASCULARIZATION 审中-公开
标题翻译：用于在重新血液化期间起搏的方法和设备
公开(公告)号：WO2006115693A2
公开(公告)日：2006-11-02
申请号：PCT/US2006011972
申请日：2006-03-30
申请人： CARDIAC PACEMAKERS INC , SHUROS ALLAN , BAYNHAM TAMARA COLETTE , QU JIHONG , PASTORE JOSEPH M , KRAMER ANDREW P , PRINZEN FRITS W , VANAGT WARD Y R , CORNELUSSEN RICHARD N
发明人： SHUROS ALLAN , BAYNHAM TAMARA COLETTE , QU JIHONG , PASTORE JOSEPH M , KRAMER ANDREW P , PRINZEN FRITS W , VANAGT WARD Y R , CORNELUSSEN RICHARD N
IPC分类号： A61N1/37 , A61B18/14 , A61M25/00
CPC分类号： A61N1/362 , A61B17/22 , A61B18/1492 , A61B2017/22001 , A61B2018/00214 , A61B2018/0041 , A61B2018/00422 , A61N1/056 , A61N1/3625 , A61N5/1001 , A61N2001/0585
摘要： Cardiac protection pacing is applied to prevent or reduce cardiac injury and/or occurrences of arrhythmia associated with an ischemic event including the occlusion of a blood vessel during a revascularization procedure. Pacing pulses are generated from a pacemaker and delivered through one or more pacing electrodes incorporated onto a percutaneous transluminal vascular intervention (PTVI) device used in the revascularization procedure. The pacemaker generates the pacing pulses according to a predetermined cardiac protection pacing sequence before, during, and/or after the ischemic event.
摘要翻译：应用心脏保护起搏以预防或减少心脏损伤和/或与缺血事件相关的心律失常的发生，所述缺血事件包括血管重建术过程中血管的闭塞。起搏脉冲由心脏起搏器产生并通过一个或多个起搏电极输入，所述起搏电极结合到血管再通术中使用的经皮腔内血管介入（PTVI）装置上。起搏器根据预先确定的心脏保护起搏序列在缺血事件之前，期间和/或之后产生起搏脉冲。

2. 发明申请

WO2007133962A3 CARDIAC PROTECTION PACING METHOD AND APPARATUS 审中-公开
标题翻译：心脏保护方法和装置
公开(公告)号：WO2007133962A3
公开(公告)日：2008-01-10
申请号：PCT/US2007068217
申请日：2007-05-04
申请人： CARDIAC PACEMAKERS INC , BAYNHAM TAMARA COLETTE , SPINELLI JULIO C , PRINZEN FRITS W , CORNELUSSEN RICHARD N , VANAGT WARD Y R
发明人： BAYNHAM TAMARA COLETTE , SPINELLI JULIO C , PRINZEN FRITS W , CORNELUSSEN RICHARD N , VANAGT WARD Y R
IPC分类号： A61N1/362 , A61N1/365 , A61N1/372
CPC分类号： A61N1/36557 , A61B5/026 , A61N1/3621 , A61N1/36521 , A61N1/36564 , A61N1/36578 , A61N1/36592 , A61N1/3702
摘要： A pacing system delivers cardiac protection pacing to protect the heart from injuries associated with ischemic events. The pacing system detects an ischemic event and, in response, initiates one or more cardiac protection pacing sequences each including alternative pacing and non-pacing periods. In one embodiment, the pacing system initiates a cardiac protection pacing sequence in response to the detection of the onset of an ischemic event, such that a pacing concurrent conditioning therapy is applied during the detected ischemic event.
摘要翻译：起搏系统提供心脏保护起搏，以保护心脏免受与缺血事件相关的损伤。起搏系统检测缺血事件，并作为响应启动一个或多个心脏保护起搏序列，每个起搏序列包括替代起搏和非起搏期。在一个实施例中，响应于检测到缺血事件的发作，起搏系统启动心脏保护起搏序列，使得在检测到的缺血事件期间应用起搏并发调节疗法。

3. 发明申请

WO2004096345A3 CARDIAC PACING FOR OPTIMAL INTRA-LEFT VENTRICULAR RESYNCHRONIZATION 审中-公开
标题翻译： CARDIAC PACING用于最佳的左心室再生
公开(公告)号：WO2004096345A3
公开(公告)日：2005-02-03
申请号：PCT/US2004011649
申请日：2004-04-14
申请人： MEDTRONIC INC , PRINZEN FRITS W , VERBEEK MARCEL A E
发明人： PRINZEN FRITS W , VERBEEK MARCEL A E
IPC分类号： A61N1/368 , A61N1/365
CPC分类号： A61N1/368
摘要： Cardiac pacing to treat ventricle dysynchrony for improved cardiac function is performed as follows. Early paced inter-ventricular asynchrony is determined during ventricular pacing. Baseline inter-ventricular asynchrony is determined without pacing. Average inter-ventricular asynchrony is calculated by averaging the early paced inter-ventricular asynchrony and the baseline inter-ventricular asynchrony. Atrio-ventricular delay and ventricular-ventricular delay are adjusted during ventricular pacing to yield the average nter-ventricular asynchrony for optimal intra-left ventricular resynchronization and maximal cardiac function. The elements above can be configured in software contained in an implantable medical device or embodied as a computer software product that includes a medium readable by a processor.
摘要翻译：心脏起搏治疗心室异常以改善心脏功能如下进行。在心室起搏期间确定早期起搏心室间不同步。确定基线心室间不同步，无起搏。平均心室间异常是通过平均早期起搏心室间不同步和基线心室间不同步来计算的。在心室起搏期间调节心室延迟和心室 - 心室延迟，以产生最佳左心室再同步和最大心脏功能的平均心室不同步。上述元件可以用包含在可植入医疗设备中的软件来配置，或者被实现为包括可由处理器读取的介质的计算机软件产品。

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