专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

41. 发明申请

WO2005018342A8 COMPOSITIONS AND METHODS FOR THE MAINTENANCE OF ORAL HEALTH 审中-公开
标题翻译：用于维持口腔健康的组合物和方法
公开(公告)号：WO2005018342A8
公开(公告)日：2006-03-30
申请号：PCT/US2004025899
申请日：2004-08-10
申请人： ORAGENICS INC , HILLMAN JEFFREY D
发明人： HILLMAN JEFFREY D
IPC分类号： A23L1/30 , A61P1/02 , A61K35/74
CPC分类号： A61K8/99 , A23L33/135 , A23Y2240/81 , A61K9/0053 , A61K9/0056 , A61K9/0058 , A61K35/744 , A61K2035/115 , A61Q11/00 , C12N1/20 , Y10S435/822 , Y10S435/885
摘要： The invention provides compositions comprising one or more isolated LDH-deficient mutans streptococcus strains and one or more isolated S. oralis strains and/or one or more isolated S. uberis strains. Compositions of the invention are useful to maintain oral health, by for example treating and/or preventing one or more symptoms of dental caries, periodontitis and/or other oral cavity diseases or wounds.
摘要翻译：本发明提供了包含一种或多种分离的LDH缺陷型变形链球菌链球菌菌株和一种或多种分离的口腔oral病毒株和/或一种或多种分离的乳房链球菌菌株的组合物。本发明的组合物通过例如治疗和/或预防龋齿，牙周炎和/或其它口腔疾病或伤口的一种或多种症状来维持口腔健康是有用的。

42. 发明申请

WO2005060498A2 COMPOSITION AND METHOD FOR INHIBITING SALMONELLA AND CAMPYLOBACTER COLONIZATION IN POULTRY 审中-公开
标题翻译：用于抑制家禽中沙门氏菌和弯孢菌菌落的组合物和方法
公开(公告)号：WO2005060498A2
公开(公告)日：2005-07-07
申请号：PCT/US2004/039142
申请日：2004-11-22
申请人： UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. , DOYLE, Michael, P. , ZHANG, Guodong , MA, Li
发明人： DOYLE, Michael, P. , ZHANG, Guodong , MA, Li
IPC分类号： A01N63/00 , A61K35/74 , A61K35/744 , A61K35/747 , C12N1/00 , C12N1/20 , C12R1/225 , C12R1/46
CPC分类号： C12R1/225 , A01N63/00 , A23K10/18 , A23K40/10 , A23K50/60 , A23K50/75 , A61K35/744 , A61K35/747 , C12N1/20 , C12R1/46 , Y10S424/826 , Y10S435/853 , Y10S435/885
摘要： One embodiment of the present invention is directed to the use of a novel competitive exclusion bacterial composition to prevent or reduce Salmonella or Campylobacter colonization in poultry.
摘要翻译：本发明的一个实施方案涉及新型竞争性排斥细菌组合物用于预防或减少家禽中沙门氏菌或弯曲杆菌定居的用途

43. 发明申请

WO2003055984A1 NEW STRAIN OF LACTIC ACID BACTERIUM AND EDIBLE COMPOSITIONS, DRUGS AND VETERINARY PRODUCTS CONTAINING IT 审中-公开
标题翻译：新鲜的酸性细菌和食用组合物，含有其的药物和兽医产品
公开(公告)号：WO2003055984A1
公开(公告)日：2003-07-10
申请号：PCT/IT2002/000812
申请日：2002-12-19
申请人： ACTIAL FARMACÊUTICA LDA. , VSL PHARMACEUTICALS INC. , DE SIMONE, Claudio
发明人： DE SIMONE, Claudio
IPC分类号： C12N1/20
CPC分类号： A61K31/34 , A23L33/135 , A23Y2220/67 , A23Y2240/75 , A23Y2300/45 , A61K31/56 , A61K31/685 , A61K35/744 , A61K35/745 , A61K35/747 , C12N1/20 , C12R1/46 , Y10S435/885 , A61K2300/00
摘要： Describes a new strain of Streptococcus thermophilus ssp. Salivarius (deposited on 4 December 2001 at the DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH, Braunschweig, Germany, with accession No. DSM 14667) and edible compositions, drugs and veterinary products containing it. The use of the said strain is particularly effective in the prevention/treatment of hepatic steatosis (fatty liver) and in nonalcoholic hepatic steatosis.
摘要翻译：描述了一种新的嗜热链球菌（Streptococcus thermophilus）ssp菌株。（i）Salivarius （于2001年12月4日在DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH（德国Braunschweig，保藏号DSM 14667））和含有它的食用组合物，药物和兽药产品保藏。所述菌株的使用在肝脂肪变性（脂肪肝）和非酒精性肝脂肪变性的预防/治疗中特别有效。

44. 发明申请

WO0145722A9 SOMNOGENIC ACTIVITY OF NON-PATHOGENIC LACTIC ACID BACTERIA 审中-公开
标题翻译：非致病性酸性细菌的致瘤活性
公开(公告)号：WO0145722A9
公开(公告)日：2002-09-12
申请号：PCT/EP0013020
申请日：2000-12-20
申请人： GERVAIS DANONE SA
发明人： KRUEGER JAMES M , PABST MICHAEL J , CAYUELA CHANTAL , DEGIVRY MARIE-CHRISTINE , HARTLEY DONNA
IPC分类号： A23L1/30 , A23C9/123 , A23C11/10 , A23L1/03 , A61K35/74 , A61P25/20 , C12R1/225 , C12R1/46
CPC分类号： C12R1/225 , A23C9/1234 , A23C9/1238 , A23C11/106 , A23L29/065 , A61K35/747 , C12R1/46 , Y10S435/854 , Y10S435/885
摘要： Non-pathogenic lactic acid bacteria have cell walls which are susceptible to digestion by muramidase-type enzymes, which produce fragments referred to as muramylpeptides. The ingestion of muramylpeptides, either directly, or by digestion of non-pathogenic lactic acid bacteria, promote sleep and improves the quality of sleep. In particular, non-rapid eye movement sleep phase enhanced. The muramylpeptide digestion-products of non-pathogenic lactic acid bacteria promote monocyte production of superoxide anion and the cytokines of IL-1 beta and TNF alpha .
摘要翻译：非致病性乳酸菌具有容易被消灭的胞壁蛋白酶抑制的细胞壁，产生称为胞壁酰胺肽的片段。直接或通过消化非致病性乳酸菌摄入胞壁酰胺促进睡眠，提高睡眠质量。特别是非快速眼动睡眠期增强。非致病性乳酸菌的胞壁酰胺消化产物促进超氧化物阴离子和IL-1β和TNFα的细胞因子的单核细胞产生。

45. 发明申请

WO99059413A1 A BENEFICIAL MICROBE COMPOSITION, NEW PROTECTIVE MATERIALS FOR THE MICROBES, THE METHOD TO PREPARE AND USES THEREOF 审中-公开
标题翻译：微生物的优点微生物组合物，微生物的新保护材料，其制备方法及其用途
公开(公告)号：WO99059413A1
公开(公告)日：1999-11-25
申请号：PCT/US1999/010773
申请日：1999-05-14
IPC分类号： A01N63/00 , A01N65/00 , C12N1/00 , C12N1/20
CPC分类号： C12R1/225 , Y10S435/853 , Y10S435/854 , Y10S435/885
摘要： This invention provides a microbe composition comprising three viable and beneficial lactic acid producing bacteria of new strains: Bifidobacterium bifidum 6-1 (CCTCC Number M 98003), Lactobacillus acidophilus YIT 2004 (CCTCC Number M 98004) and Streptococcus faecalis YIT 0027 (CCTCC Number M 98005). This invention also provides the materials to protect the viability of the lactic acid producing bacteria in lyophilized form and the method to prepare the composition. Finally, this invention provides various uses of the composition.
摘要翻译：本发明提供一种微生物组合物，其包含新的菌株的三种有效和有益的乳酸生产细菌：双歧双歧杆菌6-1（CCTCC号M 98003），嗜酸乳杆菌YIT 2004（CCTCC号M 98004）和粪链球菌YIT 0027（CCTCC M号 98005）。本发明还提供了用于保护冻干形式的乳酸生产细菌的活力的材料以及制备组合物的方法。最后，本发明提供了组合物的各种用途。

46. 发明申请

WO98045469A1 UNIVERSAL TEST SYSTEMS AND METHODS OF USE THEREOF FOR IDENTIFYING MULTIPLE FAMILIES OF MICROORGANISMS 审中-公开
标题翻译：通用测试系统及其使用方法用于识别微生物的多个家族
公开(公告)号：WO98045469A1
公开(公告)日：1998-10-15
申请号：PCT/US1998/005097
申请日：1998-03-16
IPC分类号： C12Q1/04 , C12Q1/00
CPC分类号： C12Q1/04 , Y10S435/843 , Y10S435/851 , Y10S435/853 , Y10S435/871 , Y10S435/882 , Y10S435/885 , Y10S435/968
摘要： The present invention relates to universal test systems and methods of use thereof for identifying a microorganism among at least two groups of widely divergent microorganisms. The universal test system comprises a predetermined combination of non-redundant biochemical tests comprising a substrate for at least one enzyme wherein the substrate, if acted on by the enzyme results in formation of a detectable product. Detectable products from the combination of biochemical tests are then used to identify the microorganism.
摘要翻译：本发明涉及通用测试系统及其使用方法，用于在至少两组广泛分散的微生物中识别微生物。通用测试系统包括非冗余生物化学测试的预定组合，其包含用于至少一种酶的底物，其中如果由酶起作用的底物导致可检测产物的形成。然后使用生物化学检测结合的可检测产物鉴定微生物。

47. 发明申请

WO1996023896A1 ANTITUMOR AND ANTICHOLESTEROL PREPARATIONS CONTAINING A LIPOTEICHOIC ACID FROM STEPTOCOCCUS 审中-公开
标题翻译：含有来自STEPTOCOCCUS的LIPOTEICHOIC酸的抗菌素和抗胆固醇制剂
公开(公告)号：WO1996023896A1
公开(公告)日：1996-08-08
申请号：PCT/EP1996000309
申请日：1996-01-24
申请人： TRUOG, Peter , RÖTHLISBERGER, Peter
IPC分类号： C12P19/44
CPC分类号： C07H15/04 , A61K38/212 , A61K38/51 , C07H15/06 , C12P19/44 , Y10S435/885 , A61K31/70 , A61K2300/00
摘要： The invention concerns a new lipoteichoic acid which can be isolated from the new Streptococcus sp DSM 8747. The new LTA is called LTA-T. It has a lipid anchor, which is a galacto-furanosyl-beta-1-3-glycerol with different rests of fatty acids esterified to the two adjacent hydroxy groups in the glycerol moiety and a non-glycosylated, linear, unbranched GroP chain with an unusual short hydrophilic GroP chain. The hydrophilic backbone consists of only 10 glycerophosphate units esterified with D-alanine in an extent of 30 %. The invention further concerns a pharmaceutical composition with the new LTA-T, optionally together with a monokine and/or hyaluronidase, a method of treating cancer comprising administration of an antitumor effective amount thereof, a method of producing the new compound and the new pharmaceutical composition, two degradation products of the new LTA-T and their use, and the new Streptococcus strain from which the new compound can be isolated.
摘要翻译：本发明涉及可以从新型链球菌DSM 8747中分离的新的脂磷壁酸。新的LTA称为LTA-T。它具有脂质锚，其是半乳糖 - 呋喃糖基-β-1-3-甘油，其中不同的脂肪酸残基被酯化到甘油部分中的两个相邻羟基和非糖基化，线性，无支链的GroP链，其具有不寻常的短亲水性GroP链。亲水性主链由只有10％D-丙氨酸酯化的10个甘油磷酸酯单元组成。本发明还涉及具有新的LTA-T，任选地与单核因子和/或透明质酸酶一起使用的治疗癌症的方法的药物组合物，包括施用抗肿瘤有效量的方法，制备新化合物的方法和新的药物组合物，新的LTA-T的两种降解产物及其用途，以及可以从其中分离出新化合物的新型链球菌菌株。

48. 发明申请

WO1996015435A2 MEDIUM FOR DETECTING ENTEROCOCCI IN A SAMPLE 审中-公开
标题翻译：用于在样品中检测食品的中间体
公开(公告)号：WO1996015435A2
公开(公告)日：1996-05-23
申请号：PCT/US1995013579
申请日：1995-10-23
申请人： IDEXX LABORATORIES, INC.
发明人： IDEXX LABORATORIES, INC. , CHEN, Chun-Ming , GU, Haoyi
IPC分类号： G01N00/00
CPC分类号： C12Q1/10 , Y10S435/885
摘要： Medium for growing Enterococci so that detection may be obtained within 24 hours.
摘要翻译：培养肠球菌，以便24小时内可以获得检测。

49. 发明申请

WO9533467A3 MODULATORS OF PNEUMOCOCCAL ADHERENCE TO PULMONARY AND VASCULAR CELLS AND DIAGNOSTIC AND THERAPEUTIC APPLICATIONS 审中-公开
标题翻译：肺血管密度与血管和血管细胞的调节剂和诊断和治疗应用
公开(公告)号：WO9533467A3
公开(公告)日：1996-01-04
申请号：PCT/US9507209
申请日：1995-06-06
申请人： UNIV ROCKEFELLER
发明人： TUOMANEN ELAINE I , CUNDELL DIANA R
IPC分类号： G01N33/566 , A61K9/12 , A61K9/14 , A61K9/72 , A61K31/70 , A61K31/7024 , A61K31/7028 , A61P11/00 , A61P31/04 , C07H13/06 , C07H15/04 , C12Q1/04 , G01N33/569 , A61K31/34 , A61K31/55 , G01N33/53
CPC分类号： A61K31/7016 , A61K31/7032 , C12Q1/04 , G01N33/56944 , G01N2333/315 , Y10S435/885 , Y10S435/975 , A61K31/7004 , A61K2300/00
摘要： The present invention relates to compositions and methods for preventing pneumococcal infection. In particular, this invention relates to the identification of the minimum receptor targets of pneumococcal adherence to pulmonary and vascular endothelium, and to compositions and methods for preventing such adherence. In particular, the invention relates to the ability of one or more carbohydrate entities having the following motif or motifs: a disaccharide N-acetyl-D-galactosamine β1-3Gal motif, a disaccharide N-acetyl-D-galatosamine β1-4Gal motif, and an N-acetyl-D-glucosamine motif, effective to induce elution of adherent S. pneumoniae from host cells. In particular, a composition containing all three motifs can elute about 100 % of pneumococcal bacteria from lung epithelial cells, and from venous endothelial cells. In a particular embodiment, a pharmaceutical composition of the invention can be used to treat pneumococcal infections in which the host cells are lung epithelial cells. For use in blocking adherence to, or eluting adherent bacteria from, lung epithelial cells, the pharmaceutical composition is an aerosol formulation. The invention further provides formulations for parenteral administration for treating systemic blood-borne infections by preventing or reversing binding to venous endothelial cells. The invention further relates to methods and kits for determining the presence of pneumococci in a biological sample from a subject.

50. 发明申请

WO1991009608A1 PHARMACEUTICAL PREPARATION FOR CONTROLLING PATHOGENIC INTESTINAL BACTERIA 审中-公开
标题翻译：用于控制病原体细菌的药物制备
公开(公告)号：WO1991009608A1
公开(公告)日：1991-07-11
申请号：PCT/SE1990000850
申请日：1990-12-19
申请人： GRAHN, Eva, Elisabeth , HOLM, Stig, Edvin, Folke
IPC分类号： A61K35/74
CPC分类号： B01J23/622 , A23C9/1236 , A23K10/18 , A61K35/744 , B01J27/10 , C07C5/226 , C07C2521/04 , C07C2523/14 , C07C2523/42 , C07C2523/62 , Y10S435/885
摘要： A pharmaceutical preparation for controlling pathogenic microorganisms causing diarrhoea and other gastrointestinal troubles in man and in animals contains Streptococcus lactis strain LIa in at least one pharmaceutically acceptable carrier medium in which the microorganism retains its viability. The use of the preparation for controlling pathogenic microorganisms causing diarrhoea and other gastrointestinal infections in man and in animals is also described.
摘要翻译：用于控制在人和动物中引起腹泻和其他胃肠道疾病的致病微生物的药物制剂在至少一种药学上可接受的载体介质中含有乳链球菌菌株LIa，其中微生物保持其活力。还描述了用于控制在人和动物中引起腹泻和其他胃肠道感染的致病微生物的制剂的用途。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式