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1. 发明申请

WO2017167660A1 USE OF GLUCOSE DEFICIENT STREPTOCOCCUS THERMOPHILES STRAINS IN A PROCESS FOR PRODUCING FERMENTED MILK PRODUCTS 审中-公开
标题翻译：葡萄糖缺陷型链球菌热亲和菌株在生产发酵乳产品的过程中的应用
公开(公告)号：WO2017167660A1
公开(公告)日：2017-10-05
申请号：PCT/EP2017/057083
申请日：2017-03-24
申请人： CHR. HANSEN A/S
发明人： CHRISTENSEN, Nanna , HOEGHOLM, Tina , JENSEN, Pia Frost , SVANE, Claus
IPC分类号： A23C9/12 , A23C9/127 , A23C19/032 , A23C17/02 , A23C9/123 , C12N1/20 , C12N9/12
CPC分类号： C12N9/1205 , A23C9/1234 , A23C9/1238 , A23C19/0684 , A23Y2240/75 , C07K14/315 , C12N1/20 , C12R1/225 , C12R1/23 , C12R1/46
摘要： The invention relates to the use of a Streptococcus thermophilus strain with a deficiency in glucose metabolism for improving growth of a Lactobacillus strain in a process for producing a fermented milk product.
摘要翻译：本发明涉及具有缺乏葡萄糖代谢的嗜热链球菌菌株在用于改进乳杆菌属菌株生长的方法中的用途，生产发酵奶产品。

2. 发明申请

WO2017131402A1 면역조절 작용을 가는 사람 소화관 유래 신규 유산균 및 이의 용도 审中-公开
标题翻译：来源于消化道的新型乳酸菌及其应用
公开(公告)号：WO2017131402A1
公开(公告)日：2017-08-03
申请号：PCT/KR2017/000792
申请日：2017-01-24
申请人： 경희대학교 산학협력단
发明人： 김동현 , 한명주
IPC分类号： C12N1/20 , A23L33/135 , A61K35/744 , A61K35/745 , A61K35/747 , C12R1/01 , C12R1/225 , C12R1/23 , C12R1/25 , C12R1/46
CPC分类号： A23L33/135 , A61K35/744 , A61K35/745 , A61K35/747 , C12N1/20 , C12R1/01 , C12R1/225 , C12R1/23 , C12R1/25 , C12R1/46
摘要： 본 발명에 따른 특정 락토바실러스속 균주, 특정 비피도박테리움속 균주, 특정 스트렙토코커스속 균주 또는 특정 콜린셀라속 균주는 사람의 분변에서 분리되어 안전성이 높고 면역조절 효능, 면역증강 효능, 항알러지 효능, 항염증 효능, 대장염 개선 효능, 관절염 개선 효능, 항비만 효능, 항스트레스 효능, 항불안 효능, 항우울 효능 또는 항정신분열 효능과 같은 다양한 생리활성을 갖는다. 본 발명에 따른 특정 락토바실러스속 균주, 특정 비피도박테리움속 균주, 특정 스트렙토코커스속 균주 또는 특정 콜린셀라속 균주는 면역조절, 면역증강, 염증반응 억제, 스트레스 완화를 위한 소재로 사용될 수도 있고, 알러지 질환, 염증 질환, 대장염, 관절염, 비만, 불안 장애, 우울증 또는 정신분열증 등을 예방, 개선 또는 치료하는데에 유용한 기능성 식의약 소재로도 사용될 수 있다.
摘要翻译：
特定乳酸杆菌，具体双歧杆菌菌株，某些链球菌属或根据本发明的特定胆碱酒窖SP被从人类粪便高安全性的免疫调节作用分离具有免疫增强作用，抗过敏作用，抗炎症功效，改善的效力结肠炎，关节炎改善效能，抗肥胖作用和抗应激功效，抗焦虑作用，抗抑郁功效或其中各种生理活性如精神分裂症功效。根据本发明的特定乳酸杆菌，具体双歧杆菌菌株，某些链球菌属或特定胆碱地窖SP可以被用作用于免疫调节的材料，增强免疫力，炎症抑制，消除应力，过敏性疾病，炎性疾病，其也可以用作结肠炎，关节炎，肥胖，焦虑，抑郁，或功能性表达如药材预防精神分裂症是有用的，改善或治疗。

3. 发明申请

WO2017108126A1 COMPOSITIONS AND METHODS FOR INCREASING OR MAINTAINING FAECALIBACTERIUM PRAUSNITZII POPULATIONS 审中-公开
标题翻译：增加或维持脆弱类群的组合物和方法
公开(公告)号：WO2017108126A1
公开(公告)日：2017-06-29
申请号：PCT/EP2015/081148
申请日：2015-12-23
申请人： COMPAGNIE GERVAIS DANONE
发明人： DERRIEN, Muriel , LEBAS, Mathilde , GARAULT, Peggy
IPC分类号： C12R1/145 , C12R1/46 , A23C9/123 , A61K35/74 , C12N1/20 , A23L33/10
CPC分类号： A23L33/135 , A23C9/123 , A23C9/1236 , A23C9/1238 , A23Y2240/41 , A23Y2240/75 , A61K35/744 , C12N1/20 , C12R1/46
摘要： The present invention relates to the use of at least one lactic acid bacterium, or a composition comprising thereof or conditioned thereby, for increasing or maintaining a Faecalibacterium prausnitzii population.
摘要翻译：本发明涉及至少一种乳酸菌或包含其或由其调节的组合物用于增加或维持Faecalibacterium prausnitzii种群的用途。 p>

4. 发明申请

WO2015124718A1 PHAGE INSENSITIVE STREPTOCOCCUS THERMOPHILUS 审中-公开
标题翻译： PHAGE隐性STREPTOCOCCUS热水器
公开(公告)号：WO2015124718A1
公开(公告)日：2015-08-27
申请号：PCT/EP2015/053601
申请日：2015-02-20
申请人： DSM IP ASSETS B.V.
发明人： KOUWEN, Roelof Hendrik Matthijs , HEE, VAN, Pim , VAN SINDEREN, Douwe , MCDONNELL, Brian , MAHONY, Jennifer
IPC分类号： C12N15/01 , C12N15/10 , C12Q1/68 , A23C9/123 , C12R1/46
CPC分类号： C12R1/46 , A23C9/1238 , A23C19/0323 , A23Y2240/75 , C12N1/04 , C12N1/20 , C12N15/01 , C12Q1/689 , G06F19/22
摘要： Bacteriophage Insensitive Mutants (BIMs) of three Streptococcus thermophilus parent strains were generated and characterized for phage sensitivity, sedimentation rate, cell chain length, phage adsorption and CRISPR locialterations. Several BIMs showed an altered sedimentation phenotype as well as an increase cell chain length, reduced phage sensitivity, reduced phage adsorption and 100% identity in three CRISPR loci. The results show that the derived BIMs have become phage-resistant through a mechanism other than CRISPR.
摘要翻译：产生三种嗜热链球菌亲本菌株的噬菌体不敏感突变体（BIM），其特征在于噬菌体敏感性，沉降速率，细胞链长度，噬菌体吸附和CRISPR定位。几个BIM显示出改变的沉降表型以及增加的细胞链长度，降低的噬菌体敏感性，减少的噬菌体吸附和100个同一性在三个CRISPR基因座。结果表明，衍生的BIMs通过CRISPR以外的机制已经成为抗噬菌体。

5. 发明申请

WO2015100405A1 METHOD OF PRODUCING PARTIALLY PURIFIED EXTRACELLULAR METABOLITE PRODUCTS FROM BACILLUS COAGULANS AND BIOLOGICAL APPLICATIONS THEREOF 审中-公开
标题翻译：生产部分纯化的细菌性代谢产物的方法及其生物应用
公开(公告)号：WO2015100405A1
公开(公告)日：2015-07-02
申请号：PCT/US2014/072331
申请日：2014-12-24
申请人： MAJEED, Muhammed
发明人： MAJEED, Muhammed , NAGABHUSHANAM, Kalyanam , ARUMUGAM, Sivakumar , ALI, Furqan
IPC分类号： C12N1/20
CPC分类号： A01N63/02 , A01N31/08 , A01N37/12 , C12N1/20 , C12R1/07 , C12R1/085 , C12R1/19 , C12R1/385 , C12R1/42 , C12R1/445 , C12R1/45 , C12R1/46 , A01N65/08
摘要： Disclosed is a method for producing partially purified extracellular metabolite preparation from the probiotic bacterial strain Bacillus coagulans SBC-37 (Deposited in the Microbial Type Culture Collection and Gene Bank as strain number MTCC 5856) exhibiting 99% genetic homology with the known bacterial strains Bacillus coagulans ATCC 31284, Bacillus coagulans NBRC 3887 and Bacillus coagulans ATCC 7050. Also disclosed is the anti-microbial profile of said extracellular metabolite preparation against a panel of microbial pathogens, including synergistic anti-microbial effects of preparation when combined with a synergistic preservative blend comprising from about 61% w/w of thymol, about 38% of monolaurin and about 1% w/w of magnolol obtained from supercritical fluid extracts of Magnolia officinalis. The extracellular metabolite preparation alone or the combination of said extracellular metabolite preparation and preservative blend also inhibits microbial biofilm formation in a synergistic manner.
摘要翻译：公开了一种从已知菌株凝结芽孢杆菌（Bacillus coagulans）显示出99％的遗传同源性的益生菌菌株凝结芽孢杆菌凝结芽孢杆菌SBC-37（沉积在微生物型培养物收集和基因库中的菌株号MTCC 5856）的部分纯化细胞外代谢物制剂的方法 ATCC 31284，凝结芽孢杆菌NBRC 3887和凝结芽孢杆菌ATCC 7050.还公开了所述细胞外代谢产物针对一组微生物病原体的抗微生物特征，包括与协同防腐混合物组合时的制备的协同抗微生物作用，约61％w / w的百里酚，约38％的单月桂酸和约1％w / w的从木兰超临界流体提取物获得的厚朴酚。单独的胞外代谢物制剂或所述细胞外代谢物制剂和防腐剂混合物的组合也以协同方式抑制微生物生物膜形成。

6. 发明申请

WO2015024097A1 MODERN PREFERMENT METHOD FOR MANUFACTURING DOUGH MIXTURE 审中-公开
标题翻译：用于制造DOUGH MIXTURE的现代优选方法
公开(公告)号：WO2015024097A1
公开(公告)日：2015-02-26
申请号：PCT/CA2014/000617
申请日：2014-08-13
申请人： LALLEMAND INC.
发明人： SANCHEZ JIMENA, Ana , KRAUS, Kevin
IPC分类号： C12N1/20 , A21D10/00 , A21D6/00 , A21D8/04 , C12N1/16
CPC分类号： A21D8/045 , A21D6/001 , A21D8/047 , C12R1/46
摘要： There is provided a lactic acid bacteria strain, Lactococcus lactis with accession number IDAC 270613-01, having a short fermentation lag phase of 1 to 5 hours which is compatible with modern bread making methods. Pre-ferment methods which use the strain for manufacture of leavened products and the leavened products produced therefrom are also disclosed.
摘要翻译：提供了与现代面包制作方法兼容的乳酸菌菌株，乳酸乳球菌，具有登录号IDAC 270613-01，具有1至5小时的短发酵滞后期。还公开了使用该菌株制造发酵产品的预发酵方法和由其制备的发酵产品。

7. 发明申请

WO2015014940A1 GLUCOSE SECRETING LACTIC ACID BACTERIA STRAINS 审中-公开
标题翻译：葡萄糖分泌乳酸菌菌株
公开(公告)号：WO2015014940A1
公开(公告)日：2015-02-05
申请号：PCT/EP2014/066502
申请日：2014-07-31
申请人： TINE SA
发明人： KLINKENBERG, Geir , HOLO, Helge , ØYAAS, Jorun
IPC分类号： A23C9/12 , A23C9/123 , C12N1/20 , G01N33/569
CPC分类号： G01N33/56911 , A23C9/1238 , A23Y2240/75 , C12R1/46
摘要： The present invention relates to a method for obtaining a glucose secreting lactic acid bacteria strains useful for the preparation of fermented diary products, such as e.g. yogurt, and to lactic acid bacteria strains obtained by said method.
摘要翻译：本发明涉及一种获得用于制备发酵日记产品的葡萄糖分泌型乳酸菌菌株的方法，酸奶，以及通过所述方法获得的乳酸菌菌株。

8. 发明申请

WO2012143787A8 COMPOSITION COMPRISING PROBIOTIC BACTERIA CAPABLE OF RESTORING THE BARRIER EFFECT OF THE STOMACH WHICH IS LOST DURING PHARMACOLOGICAL TREATMENT OF GASTRIC HYPERACIDITY 审中-公开
标题翻译：包含生物细菌的组合物能够恢复在胃肠病学治疗胃肠功能不全期间失去的STOMACHE的障碍效应
公开(公告)号：WO2012143787A8
公开(公告)日：2013-12-12
申请号：PCT/IB2012000779
申请日：2012-04-18
申请人： MOGNA GIOVANNI
发明人： MOGNA GIOVANNI
IPC分类号： A61K35/74 , A23L1/29 , A61K45/06 , A61P1/04 , C12R1/225
CPC分类号： A61K35/745 , A23L33/135 , A23V2002/00 , A61K35/74 , A61K35/747 , A61K45/06 , C12N1/20 , C12R1/01 , C12R1/225 , C12R1/23 , C12R1/25 , C12R1/46 , A61K2300/00 , A23V2200/3204
摘要： The present invention relates to a composition comprising probiotic bacteria for use in the pharmacological treatment of gastric hyperacidity. Said composition is capable of restoring the barrier effect of the stomach which is lost during pharmacological treatment of gastric hyperacidity and of minimizing the secondary effects due to said pharmacological treatment.
摘要翻译：本发明涉及一种用于药物治疗胃酸过度的益生菌的组合物。所述组合物能够恢复在胃酸过量的药理学治疗期间损失的胃的屏障作用，并且使由于所述药物治疗引起的次要作用最小化。

9. 发明申请

WO2013026033A2 STRAINS AND METHODS USEFUL FOR MYCOTOXINS 审中-公开
标题翻译：应用于霉菌毒素的菌株和方法
公开(公告)号：WO2013026033A2
公开(公告)日：2013-02-21
申请号：PCT/US2012/051452
申请日：2012-08-17
申请人： DUPONT NUTRITION BIOSCIENCES APS , DAVIS, Mari Ellen , REHBERGER, Joshua , NOVAK, Kimberly , REHBERGER, Thomas G.
发明人： DAVIS, Mari Ellen , REHBERGER, Joshua , NOVAK, Kimberly , REHBERGER, Thomas G.
IPC分类号： C12N1/20 , A61P1/00 , A61P37/02 , A61K35/74
CPC分类号： A61K35/742 , A61K35/747 , A61K2035/11 , C12R1/10 , C12R1/125 , C12R1/225 , C12R1/24 , C12R1/46
摘要： The disclosure relates to strains, compositions and methods for detoxifying a mycotoxin. In another embodiment, the disclosure relates to strains, compositions and methods for alleviating the gastrointestinal inflammatory response resulting from ingestion of mycotoxins. In one embodiment, the strains are Bacillus strains. In another embodiment, the strains are lactic acid bacteria.
摘要翻译：本公开涉及用于解毒霉菌毒素的菌株，组合物和方法。在另一个实施方案中，本公开涉及用于缓解由摄入真菌毒素引起的胃肠炎症反应的菌株，组合物和方法。在一个实施方案中，菌株是芽孢杆菌菌株。在另一个实施方案中，菌株是乳酸菌。

10. 发明申请

WO2013024178A1 METHOD FOR PURIFYING BACTERIAL CELLS 审中-公开
标题翻译：净化细菌细胞的方法
公开(公告)号：WO2013024178A1
公开(公告)日：2013-02-21
申请号：PCT/EP2012/066208
申请日：2012-08-20
申请人： CHR. HANSEN A/S , GEORGIEVA, Tania Ivanova , CLAUSEN, Anders , THORSEN, Tina Malling
发明人： GEORGIEVA, Tania Ivanova , CLAUSEN, Anders , THORSEN, Tina Malling
IPC分类号： C12N1/04 , C12R1/225 , C12R1/23
CPC分类号： C12N1/20 , C12N1/04 , C12R1/01 , C12R1/225 , C12R1/23 , C12R1/46
摘要： The present invention relates to a process for providing purified bacteria-containing concentrates, comprising at least the steps of adding an aqueous solution to a first bacteria- containing concentrate to provide a bacteria-containing suspension, wherein the volume of the added aqueous solution is in the range of 0.3 liters to 10 liters per liter of said first bacteria- containing concentrate; and concentrating said bacteria-containing suspension to provide a second bacteria-containing concentrate. Further, the present invention relates to the purified concentrates per se.
摘要翻译：本发明涉及提供纯化的含细菌的浓缩物的方法，该方法至少包括将水溶液加入第一含细菌的浓缩物中以提供含细菌的悬浮液，其中加入的水溶液的体积为每升所述第一含细菌浓缩物0.3升至10升的范围; 并浓缩所述含细菌的悬浮液以提供第二细菌浓缩物。此外，本发明涉及纯化的浓缩物本身。

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