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21. 发明申请

WO2011123789A1 COMBINATION HEART ASSIST SYSTEMS, METHODS, AND DEVICES 审中-公开
标题翻译：组合心脏辅助系统，方法和装置
公开(公告)号：WO2011123789A1
公开(公告)日：2011-10-06
申请号：PCT/US2011/030954
申请日：2011-04-01
申请人： SUNSHINE HEART COMPANY PTY LTD , PETERS, William, S. , PARKIN, Rodney, G. , ROSA, David , LAFONTAINE, Daniel, M. , ABRAHAM, William, T. , SUN, Benjamin
发明人： PETERS, William, S. , PARKIN, Rodney, G. , ROSA, David , LAFONTAINE, Daniel, M. , ABRAHAM, William, T. , SUN, Benjamin
IPC分类号： A61M1/10 , A61M1/12 , A61N1/365
CPC分类号： A61N1/3702 , A61B5/0084 , A61B5/02028 , A61B5/021 , A61B5/026 , A61B5/0402 , A61B5/4836 , A61B5/686 , A61B7/023 , A61B7/04 , A61M1/006 , A61M1/1055 , A61M1/106 , A61M1/1067 , A61M1/1068 , A61M1/1072 , A61M1/1086 , A61M1/12 , A61M1/122 , A61M2205/33 , A61M2205/3303 , A61N1/3627 , A61N1/36514 , A61N1/36521 , A61N1/36542 , A61N1/3962
摘要： The various embodiments disclosed herein relate to combination heart assist systems, methods, and devices that include both an electrical therapy device and a mechanical heart assist device. Various operational modes can be implemented using these embodiments, including a synchronized pacing mode, an internal CPR mode, and an internal workout mode.
摘要翻译：本文公开的各种实施例涉及包括电疗设备和机械心脏辅助装置的组合心脏辅助系统，方法和装置。可以使用这些实施例来实现各种操作模式，包括同步起搏模式，内部CPR模式和内部锻炼模式。

22. 发明申请

WO2009099597A1 MULTI-SITE ATRIAL ELECTROSTIMULATION 审中-公开
标题翻译：多场ATRIAL电化学
公开(公告)号：WO2009099597A1
公开(公告)日：2009-08-13
申请号：PCT/US2009/000693
申请日：2009-02-04
申请人： CARDIAC PACEMAKERS, INC. , HASTINGS, Roger , BECKER, John, A. , PIKUS, Michael, J. , LAFONTAINE, Daniel, M. , EDMUNDS, Kevin, D.
发明人： HASTINGS, Roger , BECKER, John, A. , PIKUS, Michael, J. , LAFONTAINE, Daniel, M. , EDMUNDS, Kevin, D.
IPC分类号： A61N1/05
CPC分类号： A61N1/3787 , A61N1/0565 , A61N1/057 , A61N1/0573 , A61N1/3622 , A61N1/3624 , A61N1/3684 , A61N1/37205 , A61N1/37223 , A61N1/37229 , A61N1/3756
摘要： An apparatus and method can receive wireless energy using a wireless electrostimulation electrode assembly. In certain examples, at least some of the received wireless energy can be delivered as an electrostimulation to a heart. In certain examples, the wireless electrostimulation electrode can be mechanically supported at least partially using a ring formed by an annulus of a mitral valve of the heart. In certain examples, the wireless electrostimulation electrode assembly can be configured to be intravascularly delivered to an implant location within a chamber of the heart at the annulus of the mitral valve of the heart, and can fit entirely within the heart.
摘要翻译：一种装置和方法可以使用无线电刺激电极组件接收无线能量。在某些示例中，所接收的无线能量中的至少一些可以作为电刺激递送到心脏。在某些示例中，无线电刺激电极可以至少部分地使用由心脏的二尖瓣的环形成的环机械地支撑。在某些实例中，无线电刺激电极组件可被配置为在心脏的二尖瓣的环处血管内递送到心脏腔室内的植入位置，并且可以完全适合于心脏内。

23. 发明申请

WO2009076759A1 AUTOMATED ORDER SEQUENCING METHOD AND SYSTEM 审中-公开
标题翻译：自动排序顺序方法和系统
公开(公告)号：WO2009076759A1
公开(公告)日：2009-06-25
申请号：PCT/CA2008/002181
申请日：2008-12-15
申请人： 3584925 Canada Inc. , LAFONTAINE, Daniel, R.
发明人： LAFONTAINE, Daniel, R.
IPC分类号： B65G1/137 , B07C5/02 , B07C5/38 , B65G1/04
CPC分类号： B65G1/08 , B65G1/1376
摘要： An automated case order preparation system (100,200,300) including a crane 6 for transporting groups 4 of depalletized product cases 1 to temporary storage on shelving 30, and to a plurality of gravity-powered case guides 8, for accumulating and dispensing cases 1 to fulfill client order pallets.
摘要翻译：一种自动化案例订单准备系统（100,200,300），包括用于将卸载产品箱1的组4运送到搁架30上的临时存储的起重机6以及用于累积和分配箱1以满足客户的多个重力动力的箱子引导件8 订单托盘

24. 发明申请

WO2009046073A1 CONNECTIVE TISSUE CLOSURE DEVICE AND METHOD 审中-公开
标题翻译：连接组织封闭装置及方法
公开(公告)号：WO2009046073A1
公开(公告)日：2009-04-09
申请号：PCT/US2008/078405
申请日：2008-10-01
申请人： BOSTON SCIENTIFIC SCIMED, INC. , LAFONTAINE, Daniel M.
发明人： LAFONTAINE, Daniel M.
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B17/0401 , A61B17/0487 , A61B2017/00004 , A61B2017/00663 , A61B2017/0409 , A61B2017/0448 , A61B2017/045 , A61B2017/0488
摘要： A device (20) for closing wounds such as openings in blood vessels as well as a method of doing so are disclosed. The device employs a fabric wrapped (24) around an expandable frame (22) both of which are inserted into a blood vessel through an introducer sheath (26). Once inserted, the expandable frame expands thereby expanding the fabric therewith. The fabric is made from a bioabsorable material and includes a plurality of microhooks (62) extending therefrom. One suitable material is polylactic acid fiber. Upon retraction of the device, the microhooks engage the adventitia surrounding the blood vessel causing the fabric to remain in position sealing the opening even after the expandable member is retracted and removed as well as the introducer sheath. As the fabric is made from a bioabsorable material, the device can remain in place even after hemostasis is reached and eventually dissolve within the body.
摘要翻译：公开了用于关闭诸如血管中的开口的伤口的装置（20）以及这样做的方法。该装置采用在可扩展框架（22）周围包裹（24）的织物，两者都通过引导器护套（26）插入血管。一旦插入，可膨胀框架膨胀，从而使织物膨胀。织物由生物可吸收材料制成并且包括从其延伸的多个微钩（62）。一种合适的材料是聚乳酸纤维。当装置缩回时，微钩与血管周围的外膜接合，导致即使在可扩张构件缩回和移除以及导引鞘之后，织物也保持在密封开口的位置。由于织物由生物可吸收材料制成，所以即使达到止血之后，该装置也可以保持在适当位置，并最终溶解在体内。

25. 发明申请

WO2009099550A1 WIRELESS TISSUE ELECTROSTIMULATION 审中-公开
标题翻译：无线组织电化学
公开(公告)号：WO2009099550A1
公开(公告)日：2009-08-13
申请号：PCT/US2009/000587
申请日：2009-01-29
申请人： CARDIAC PACEMAKERS, INC. , HASTINGS, Roger , BECKER, John A. , PIKUS, Michael J. , LAFONTAINE, Daniel M. , EDMUNDS, Kevin D.
发明人： HASTINGS, Roger , BECKER, John A. , PIKUS, Michael J. , LAFONTAINE, Daniel M. , EDMUNDS, Kevin D.
IPC分类号： A61N1/378 , A61N1/362 , A61N1/05
CPC分类号： A61N1/3787 , A61N1/0565 , A61N1/057 , A61N1/0573 , A61N1/3622 , A61N1/3624 , A61N1/3684 , A61N1/37205 , A61N1/37223 , A61N1/37229 , A61N1/3756
摘要： A wireless electrostimulation system can comprise a wireless energy transmission source, and an implantable cardiovascular wireless electrostimulation node. A receiver circuit comprising an inductive antenna can be configured to capture magnetic energy to generate a tissue electrostimulation. A tissue electrostimulation circuit, coupled to the receiver circuit, can be configured to deliver energy captured by the receiver circuit as a tissue electrostimulation waveform. Delivery of tissue electrostimulation can be initiated by a therapy control unit.
摘要翻译：无线电刺激系统可以包括无线能量传输源和可植入心血管无线电刺激节点。包括感应天线的接收机电路可被配置为捕获磁能以产生组织电刺激。耦合到接收器电路的组织电刺激电路可以被配置为将由接收器电路捕获的能量作为组织电刺激波形传送。组织电刺激的递送可以由治疗控制单元启动。

26. 发明申请

WO2008034005A3 CARDIAC STIMULATION USING LEADLESS ELECTRODE ASSEMBLIES 审中-公开
标题翻译：使用无铅电极组件进行心脏刺激
公开(公告)号：WO2008034005A3
公开(公告)日：2008-07-10
申请号：PCT/US2007078405
申请日：2007-09-13
申请人： BOSTON SCIENT SCIMED INC , HASTINGS ROGER N , LAFONTAINE DANIEL M , PIKUS MICHAEL J , WILLARD MARTIN R
发明人： HASTINGS ROGER N , LAFONTAINE DANIEL M , PIKUS MICHAEL J , WILLARD MARTIN R
IPC分类号： A61N1/362 , A61N1/05 , A61N1/372 , A61N1/378
CPC分类号： A61N1/059 , A61N1/365 , A61N1/372 , A61N1/37205 , A61N1/37288 , A61N1/375 , A61N1/3756
摘要： An implantable cardiac tissue excitation system includes an implantable pacing controller unit with a pulse generation circuit. The system also includes a lead with a lead body extending between a proximal lead end attachable to the pacing controller unit and a distal lead end configured to be implanted within a heart. A lead conductor extends within the lead body. The system also includes a transmitter assembly located near the distal lead end that is electrically connected to the pulse generation circuit through the lead conductor to wirelessly transmit pacing control information and pacing energy. The system also includes a leadless electrode assembly configured to be implanted within the heart that includes a receiver to receive the wireless transmission, a charge storage unit to store the charge energy, and an electrical stimulation circuit to deliver an electrical stimulus to cardiac tissue using the pacing control information and the charge energy.
摘要翻译：可植入心脏组织激励系统包括具有脉冲发生电路的可植入起搏控制器单元。该系统还包括引线，引线本体在可附接到起搏控制器单元的近端引导端与构造成植入心脏内的远端引线端之间延伸。引线导体在引线体内延伸。该系统还包括位于远端引导端附近的发射器组件，其通过引线导体电连接到脉冲发生电路，以无线地发送起搏控制信息和起搏能量。该系统还包括被配置为植入在心脏内的无引线电极组件，其包括用于接收无线传输的接收器，用于存储充电能量的电荷存储单元，以及电刺激电路，以使用起搏控制信息和充电能量。

27. 发明申请

WO2008073214A2 THERAPEUTIC CATHETER WITH DISPLACEMENT SENSING TRANSDUCER 审中-公开
标题翻译：带位移感应传感器的治疗导管
公开(公告)号：WO2008073214A2
公开(公告)日：2008-06-19
申请号：PCT/US2007024170
申请日：2007-11-16
申请人： BOSTON SCIENT SCIMED INC , ESKURI ALAN , LAFONTAINE DANIEL
发明人： ESKURI ALAN , LAFONTAINE DANIEL
IPC分类号： A61M25/00
CPC分类号： A61B5/00 , A61B5/061 , A61B5/6848 , A61B8/12 , A61B17/3478 , A61B18/24 , A61B2017/0003 , A61B2017/00247 , A61B2018/00392 , A61B2090/062 , A61B2090/0811 , A61M5/46 , A61M25/0084
摘要： A catheter device having a proboscis, such as a needle, and a transducer which detects the axial displacement of the proboscis in relation to the distal tip or the catheter. The transducer is positioned at a distal portion of the catheter and may comprise an induction coil or a potentiometer. Axial displacement of the proboscis changes the amount of inductance or resistance in the transducer. This change in inductance or resistance can be calibrated to the amount of axial displacement of the proboscis and provided as feedback to the user.
摘要翻译：具有诸如针的长鼻子的导管装置和检测长鼻相对于远端尖端或导管的轴向位移的换能器。换能器定位在导管的远端部分，并且可以包括感应线圈或电位计。长鼻子的轴向位移会改变传感器的电感或电阻。电感或电阻的这种变化可以校准到长鼻子的轴向位移量，并作为反馈提供给用户。

28. 发明申请

WO2006113496A2 VALVE APPARATUS, SYSTEM AND METHOD 审中-公开
标题翻译：阀门装置，系统和方法
公开(公告)号：WO2006113496A2
公开(公告)日：2006-10-26
申请号：PCT/US2006/014192
申请日：2006-04-17
申请人： BOSTON SCIENTIFIC SCIMED, INC. , LAFONTAINE, Daniel M.
发明人： LAFONTAINE, Daniel M.
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61M25/1011
摘要： A cardiac valve with a first anchor frame and a cover on the first anchor frame for unidirectional flow of a liquid through the valve.
摘要翻译：一种心脏瓣膜，其具有第一锚固框架和第一锚固框架上的盖子，用于液体通过所述瓣膜的单向流动。

29. 发明申请

WO2006102023A1 TREATING INTERNAL BODY TISSUE 审中-公开
标题翻译：治疗内部身体组织
公开(公告)号：WO2006102023A1
公开(公告)日：2006-09-28
申请号：PCT/US2006/009605
申请日：2006-03-16
申请人： BOSTON SCIENTIFIC SCIMED, INC. , MARROUCHE, Nassir , LAFONTAINE, Daniel, M.
发明人： MARROUCHE, Nassir , LAFONTAINE, Daniel, M.
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B18/04 , A61B2017/00243 , A61B2017/22069 , A61B2018/0022 , A61B2018/0212
摘要： Some embodiments of the invention relate to a system for treating tissue internal to a body, such as heart tissue. For example, the system may be used to ablate tissue as a treatment for atrial fibrillation. In certain embodiments, the system is capable of causing scar tissue to form in ostial areas of the atrium rather than inside the pulmonary vein. In such embodiments, the system may include a tissue treatment member that is operable to form an annular area of ablated tissue along the outer portion of the ostium in an area known as the antrum.
摘要翻译：本发明的一些实施方案涉及用于治疗身体内部的组织例如心脏组织的系统。例如，该系统可用于消融组织作为心房颤动的治疗。在某些实施方案中，该系统能够在心房的口部区域中形成瘢痕组织，而不是在肺静脉内部。在这样的实施例中，系统可以包括组织处理构件，其可操作以沿着称为窦的区域沿着口的外部部分形成消融组织的环形区域。

30. 发明申请

WO2006045074A2 LEADLESS CARDIAC STIMULATION SYSTEMS 审中-公开
标题翻译：无铅心脏刺激系统
公开(公告)号：WO2006045074A2
公开(公告)日：2006-04-27
申请号：PCT/US2005/037978
申请日：2005-10-19
申请人： BOSTON SCIENTIFIC SCIMED, INC. , HASTINGS, Roger N. , DRASSLER, William J. , LAFONTAINE, Daniel M. , SADASIVA, Anupama , SMITH, Scott R.
发明人： HASTINGS, Roger N. , DRASSLER, William J. , LAFONTAINE, Daniel M. , SADASIVA, Anupama , SMITH, Scott R.
IPC分类号： A61N1/05 , A61N1/378 , A61N1/372 , A61M31/00
CPC分类号： A61N1/3756 , A61N1/0587 , A61N1/059 , A61N1/08 , A61N1/3627 , A61N1/365 , A61N1/37205 , A61N1/37217 , A61N1/37223 , A61N1/37229 , A61N1/37241 , A61N1/37288 , A61N1/375 , A61N1/3787
摘要： Various configurations of systems that employ leadless electrodes to provide pacing therapy are provided. In one example, a system that provides multiple sites for pacing of myocardium of a heart includes wireless pacing electrodes that are implantable at sites proximate the myocardium using a percutaneous, transluminal, catheter delivery system. Each of the electrodes contains a source of electrical energy for pacing the myocardium and is adapted to receive electromagnetic energy from a source outside the myocardium. The system also includes a source adapted for placement outside the myocardium and that uses locally measured electrocardiograms to synchronize pacing of the heart by sending electromagnetic commands to the electrodes to pace the myocardium surrounding the electrodes. Also disclosed is various configurations of such systems, wireless electrode assemblies, and delivery catheters for delivering and implanting the electrode assemblies.
摘要翻译：提供了使用无引线电极来提供起搏治疗的各种构造的系统。在一个示例中，提供用于心脏心肌的多个部位的系统包括使用经皮，经腔，导管递送系统可植入位于心肌附近的位置的无线起搏电极。每个电极包含用于起搏心肌的电能源，并且适于从心肌外部的源接收电磁能。该系统还包括适于放置在心肌外部的源，并且使用局部测量的心电图来通过向电极发送电磁命令来同步心脏的起搏，以对电极周围的心肌进行加速。还公开了用于递送和植入电极组件的这种系统，无线电极组件和输送导管的各种配置。

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