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11. 发明申请

WO2008016237A1 POLYMER INJECTABLE DETACHABLE COIL 审中-公开
标题翻译：聚合物可注射的可拆卸线圈
公开(公告)号：WO2008016237A1
公开(公告)日：2008-02-07
申请号：PCT/KR2007/003614
申请日：2007-07-27
申请人： S & G BIOTECH, INC. , KIM, Sung-Hyun , KANG, Sung-Gwon
发明人： KIM, Sung-Hyun , KANG, Sung-Gwon
IPC分类号： A61M31/00
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/1214 , A61B17/12186 , A61B2017/12063
摘要： Disclosed is a detachable coil for embolization capable of injecting a liquid polymer and useful for treating cerebral aneurysms, comprising: (I) a platinum coil part 1 for embolization in which a polymer coating film Ia is formed around an outer circumference of a platinum coil Ib having a cavity; (II) a coil pusher 2 in which an insulation coating film 2b is formed around an outer circumference of a hypo-tube 2a having a cavity; (III) a connection part 3, which includes a channel for injecting a specific polymer, that connects the platinum coil to the coil pusher and disconnects the platinum coil from the coil pusher by electrolysis; and (IV) a power supply device 4 for providing the power and performing the electrolysis of the connection part 3.
摘要翻译：公开了一种用于注射液体聚合物并可用于治疗脑动脉瘤的栓塞的可拆卸线圈，包括：（I）用于栓塞的铂线圈部分1，其中围绕铂线圈1b的外周形成聚合物涂膜1a 具有空腔; （II）线圈推动器2，其中在具有空腔的下管2a的外周形成绝缘涂层膜2b; （III）连接部3，其包括用于注入特定聚合物的通道，其将铂线圈连接到线圈推动器，并通过电解将铂线圈与线圈推动器断开; 以及（IV）用于提供电力并执行连接部3的电解的供电装置4。

12. 发明申请

WO2007073549A3 COATED EMBOLIC COILS WITH FIBERS 审中-公开
标题翻译：带纤维的涂层嵌入式线圈
公开(公告)号：WO2007073549A3
公开(公告)日：2007-10-18
申请号：PCT/US2006062243
申请日：2006-12-18
申请人： BOSTON SCIENT SCIMED INC , BUISER MARCIA S , SEEHUSEN ASHLEY , NARDONE CHRISTOPHER , DICARLO PAUL D
发明人： BUISER MARCIA S , SEEHUSEN ASHLEY , NARDONE CHRISTOPHER , DICARLO PAUL D
IPC分类号： A61F2/06 , A61B17/12 , A61L31/12
CPC分类号： A61L31/10 , A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B17/1215 , A61B2017/00526 , A61B2017/00867 , A61B2017/00898 , A61B2017/12054 , A61B2017/12063 , A61L31/16 , A61L2300/114 , A61L2430/36 , B05D1/18 , B05D7/20
摘要： Coils, such as embolic coils, and related methods, devices, and compositions, arc disclosed. It shows the primary shape of an embolic coil (10) that includes an embolic coil body (12), fiber bundles (18) attached to coil body (12), and a coating (20). Coil body (12) is formed of windings (e.g., windings 14, 15, and 16) of a wire (17) (e.g., a platinum wire). Fiber bundles (18) are formed of fibers (22) (e.g., polyester fibers). Coating (20) is disposed on the exterior surface (24) of coil body (12), and encapsulates fiber bundles (18). Embolic coil (10) may be used, for example, in an embolization procedure, and/or may be used to deliver one or more therapeutic agents to a target site.
摘要翻译：公开了诸如栓塞线圈之类的线圈以及相关方法，装置和组合物。它示出了栓塞线圈（10）的主要形状，其包括栓塞线圈体（12），附接到线圈体（12）的纤维束（18）和涂层（20）。线圈体（12）由线（17）（例如，铂线）的绕组（例如，绕组14,15和16）形成。纤维束（18）由纤维（22）（例如聚酯纤维）形成。涂层（20）设置在线圈体（12）的外表面（24）上并封装纤维束（18）。栓塞线圈（10）可用于例如栓塞过程中，和/或可用于将一种或多种治疗剂递送至靶位点。

13. 发明申请

WO2006135772A3 ASSEMBLY AND METHOD FOR FORMING AN OCCLUSION IN A VASCULAR CAVITY 审中-公开
标题翻译：用于在血管腔中形成闭塞的组装和方法
公开(公告)号：WO2006135772A3
公开(公告)日：2007-03-22
申请号：PCT/US2006022529
申请日：2006-06-09
申请人： BOSTON SCIENT SCIMED INC , GRIFFIN STEPHEN
发明人： GRIFFIN STEPHEN
IPC分类号： A61B17/12
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B90/39 , A61B2017/12063
摘要： A method and assembly for forming an occlusion within a vascular cavity. The assembly includes a catheter having an elongate shaft comprising a metallic tubular member extending from a proximal portion to a distal portion of the catheter, a delivery wire including an occlusion member detachably coupled thereto, and a power supply for providing an electrical current to initiate electrolysis at a sacrificial link between the delivery wire and the occlusion member in order to decouple the occlusion member from the delivery wire. The invention also includes a method of positioning and disposing an occlusion member within a vascular cavity using electrolysis, wherein a distal portion of the metallic tubular member serves as a first electrode and the sacrificial link serves as a second electrode. Thus, both the first electrode and the second electrode may be intravenously located proximate a vascular cavity.
摘要翻译：用于在血管腔内形成闭塞的方法和组件。组件包括具有细长轴的导管，该细长轴包括从导管的近端部分延伸到远端部分的金属管状构件，包括可拆卸地连接到其上的遮挡构件的输送线和用于提供电流以启动电解的电源在输送线和闭塞构件之间的牺牲连接处，以便将闭塞构件与输送线分离。本发明还包括一种使用电解定位和将阻塞构件设置在血管腔内的方法，其中金属管状构件的远侧部分用作第一电极，牺牲环用作第二电极。因此，第一电极和第二电极都可以静脉内定位在血管腔附近。

14. 发明申请

WO2006135772A2 ASSEMBLY AND METHOD FOR FORMING AN OCCLUSION IN A VASCULAR CAVITY 审中-公开
标题翻译：用于在血管腔中形成闭塞的组装和方法
公开(公告)号：WO2006135772A2
公开(公告)日：2006-12-21
申请号：PCT/US2006/022529
申请日：2006-06-09
申请人： BOSTON SCIENTIFIC SCIMED, INC. , GRIFFIN, Stephen
发明人： GRIFFIN, Stephen
IPC分类号： A61B17/12
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B90/39 , A61B2017/12063
摘要： A method and assembly for forming an occlusion within a vascular cavity. The assembly includes a catheter having an elongate shaft comprising a metallic tubular member extending from a proximal portion to a distal portion of the catheter, a delivery wire including an occlusion member detachably coupled thereto, and a power supply for providing an electrical current to initiate electrolysis at a sacrificial link between the delivery wire and the occlusion member in order to decouple the occlusion member from the delivery wire. The invention also includes a method of positioning and disposing an occlusion member within a vascular cavity using electrolysis, wherein a distal portion of the metallic tubular member serves as a first electrode and the sacrificial link serves as a second electrode. Thus, both the first electrode and the second electrode may be intravenously located proximate a vascular cavity.
摘要翻译：用于在血管腔内形成闭塞的方法和组件。组件包括具有细长轴的导管，该细长轴包括从导管的近端部分延伸到远端部分的金属管状构件，包括可拆卸地连接到其上的遮挡构件的输送线以及用于提供电流以启动电解的电源在输送线和闭塞构件之间的牺牲连接处，以便将闭塞构件与输送线分离。本发明还包括一种使用电解定位和将阻塞构件设置在血管腔内的方法，其中金属管状构件的远侧部分用作第一电极，牺牲环用作第二电极。因此，第一电极和第二电极都可以静脉内定位在血管腔附近。

15. 发明申请

WO2005074845A1 ENHANCING TISSUE INGROWTH FOR CONTRACEPTION 审中-公开
标题翻译：增强组织生物合成
公开(公告)号：WO2005074845A1
公开(公告)日：2005-08-18
申请号：PCT/US2005/003310
申请日：2005-01-31
申请人： OVION, INC.
发明人： CALLISTER, Jeffrey, P. , TREMULIS, William, S.
IPC分类号： A61F6/22
CPC分类号： A61B17/12022 , A61B17/12104 , A61B17/12109 , A61B17/12131 , A61B17/12136 , A61B17/12172 , A61B17/12177 , A61B17/12181 , A61B2017/00893 , A61B2017/1205 , A61B2017/12063 , A61B2017/320008 , A61F6/225
摘要： This invention is directed to occluding devices and methods of using such devices for occluding a patient’s body lumen, such as a reproductive lumen for contraceptive purposes. The occluding device generally has an occluding component (11), a first metallic element (16) associated with the occluding component, a second metallic element (17) associated with the occluding component. The first and second metallic elements are configured to generate electrical activity which enhances tissue growth into and/or onto the occluding component to aid in lumen occlusion. In one embodiment the first and second metallic elements are formed of different metallic materials and generate galvanic activity. In a second embodiment electrical power is applies to the first and second metallic elements to generate electrical activity that enhances tissue growth.
摘要翻译：本发明涉及使用这种装置遮挡患者体腔（例如用于避孕目的的生殖腔）的装置和方法。闭塞装置通常具有闭塞部件（11），与闭塞部件相关联的第一金属元件（16），与闭塞部件相关联的第二金属元件（17）。第一和第二金属元件被配置为产生电活动，其增强组织生长进入和/或闭塞组件以帮助管腔闭塞。在一个实施例中，第一和第二金属元件由不同的金属材料形成并产生电流活性。在第二实施例中，电力适用于第一和第二金属元件以产生增强组织生长的电活动。

16. 发明申请

WO2005070308A2 VORRICHTUNG ZUR IMPLANTATION VON ELEKTRISCH ISOLIERTEN OKKLUSIONSWENDELN 审中-公开
标题翻译：用于植入电绝缘闭塞磁砖的装置
公开(公告)号：WO2005070308A2
公开(公告)日：2005-08-04
申请号：PCT/EP2005/000587
申请日：2005-01-21
申请人： DENDRON GMBH , MONSTADT, Hermann
发明人： MONSTADT, Hermann
IPC分类号： A61B17/12
CPC分类号： A61B17/12195 , A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B2017/00477 , A61B2017/12063
摘要： Die Erfindung betrifft eine Vorrichtung zur Implantation von durch Elektrolyse ablösbaren Okklusionswendeln (3) in Blutgefäßen und Körperhohlräumen, insbesondere Aneurysmen (12), mit einer Einführhilfe (4), wenigstens einer distal zur Einführhilfe (4) angeordneten Okklusionswendel (3) und wenigstens einem elektrolytisch korrodierbar ausgebildeten Ablöseelement (2), wobei zwischen Ablöseelement (2) und Okklusionswendel (3) wenigstens eine Stabilisierungswendel (5) angeordnet worden ist und wobei die Stabilisierungswendel (5) über eine elektrisch isolierende Klebeschicht (7) mit der Okklusionswendel (3) verbunden ist, so daß die Okklusionswendel (3) bei Anlegen einer elektrischen Spannung an das Ablöseelement (2) von der Spannung isoliert ist. Auf diese Weise wird zum einen die Stromdichte im Ablöseelement (2) weiter erhöht, was mit kürzeren Ablösezeiten verbunden ist. Zum anderen wird die Verbindung einer der Stabilisierung des Implantates dienenden Stabilisierungswendel (5) mit der Okklusionswendel (3) im Vergleich aus dem Stand der Technik bekannten Laserschweißverfahren deutlich vereinfacht.
摘要翻译：
本发明涉及一种用于通过电解ABL＆OUML注入;在血管BEAR道南和K释放闭塞螺旋（3）＆ouml; rperhohlr树木，特别是动脉瘤（12），具有插入导航用途hrhilfe（ 4），至少一个远端导航使用用于插入和布置hrhilfe（4）闭塞螺旋（3）和至少一个电解腐蚀形成的Abl＆oUML;灵魂包换（2），其中，Abl的＆oUML之间;灵魂元件（2）和闭塞螺旋（3）至少一种稳定剂＆害羞;螺旋（ 5）已被布置，且其中所述稳定线圈（5）通过一个电绝缘的粘接剂层（7）的闭塞螺旋（3）的版本与害羞;被抑制，从而使道当电压施加到漏极元件（2）时，闭塞螺旋线（3）与电压隔离。这样，一方面，漏极元件（2）中的电流密度进一步增加，这与更短的漏极时间相关联。在另一方面，闭塞螺旋（3）的所述植入物服务稳定线圈（5）的稳定化的在现有技术中已知的激光焊接的比较化合物是ROAD过程显著简化。

17. 发明申请

WO2004091712A3 BIOACTIVE COMPONENTS FOR INCORPORATION WITH VASO-OCCLUSIVE MEMBERS 审中-公开
标题翻译：与VASO-OCCLUSIVE会员合作的生物成分
公开(公告)号：WO2004091712A3
公开(公告)日：2005-04-21
申请号：PCT/US2004011091
申请日：2004-04-09
申请人： SCIMED LIFE SYSTEMS INC
发明人： HO HANH , QUAN KENNTH W JR , TEOH CLIFFORD , EDER JOSEPH C , SLAIKEU PAUL C , WALLACE MICHAEL P , BARRY JAMES
IPC分类号： A61B17/00 , A61B17/12 , A61B19/00 , A61F2/00 , A61L31/04 , A61L31/06 , A61L31/10 , A61L31/16 , A61M29/00
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B17/1215 , A61B17/12172 , A61B17/12177 , A61B90/39 , A61B2017/00004 , A61B2017/12063 , A61F2/0077 , A61L31/044 , A61L31/06 , A61L31/10 , A61L31/16 , A61L2430/36 , C08L67/04 , C08L65/04
摘要： A vaso-occlusive device is disclosed. The device includes a vaso-occlusive member (200, 1100) having a coating disposed thereon. In accordance with one embodiment, the coating comprises a polyacrylic material. In accordance with another embodiment, the coating comprises a polyvinyl alcohol-based material. In accordance with other embodiments, various other materials and coatings are applied to at least a portion of a vaso-occlusive device.
摘要翻译：公开了一种血管闭塞装置。该装置包括其上设置有涂层的血管闭塞构件（200,1100）。根据一个实施方案，涂层包含聚丙烯酸材料。根据另一个实施方案，涂层包含聚乙烯醇基材料。根据其他实施例，各种其它材料和涂层被应用于血管闭塞装置的至少一部分。

18. 发明申请

WO2004054452A2 DETACHABLE ANEURYSM NECK BRIDGE 审中-公开
标题翻译：可拆卸的ANEURYSM NECK BRIDGE
公开(公告)号：WO2004054452A2
公开(公告)日：2004-07-01
申请号：PCT/US0336539
申请日：2003-11-13
申请人： SCIMED LIFE SYSTEMS INC
发明人： MURPHY RICHARD , WALLACE MICHAEL P , TRAN TRI , NGUYEN KIM , HO HANH , DOAN MY , ABRAMS ROBERT M , CARRISON HAROLD F
IPC分类号： A61B17/12 , A61B19/00
CPC分类号： A61B17/12113 , A61B17/12022 , A61B17/1214 , A61B17/12168 , A61B17/12172 , A61B90/39 , A61B2017/1205 , A61B2017/12063
摘要： In one embodiment, a neck bridge for bridging the neck of an aneurysm includes a junction region, a number of radially extending array elements attached to the junction region, and a cover attached to one or both of the junction region and an array element. The array elements are configured to be positioned within the aneurysm after the neck bridge is deployed from a delivery device. In a second embodiment, the neck bridge includes a junction region and a braided or mesh-like structure secured to the junction region. The braided or mesh-like structure is made from an elastic material.
摘要翻译：在一个实施例中，用于桥接动脉瘤颈部的颈桥包括连接区域，连接到接合区域的多个径向延伸的阵列元件以及附接到接合区域和阵列元件中的一个或两者的盖。阵列元件构造成在颈桥从输送装置部署之后定位在动脉瘤内。在第二实施例中，颈桥包括固定到接合区域的连接区域和编织或网状结构。编织或网状结构由弹性材料制成。

19. 发明申请

WO2003099370A2 SOLID EMBOLIC MATERIAL WITH VARIABLE EXPANSION 审中-公开
标题翻译：具有可变扩展性的固体材料
公开(公告)号：WO2003099370A2
公开(公告)日：2003-12-04
申请号：PCT/US2003/014217
申请日：2003-05-05
申请人： SCIMED LIFE SYSTEMS, INC.
发明人： MIRIGIAN, Gregory, E. , CHAN, Huey, Quoc , CHIEN, Thomas, Yung-Hui , PORTER, Stephen, C. , EURY, Robert, P.
IPC分类号： A61M25/00
CPC分类号： A61B17/12195 , A61B17/12022 , A61B17/12113 , A61B17/12136 , A61B17/12186 , A61B2017/1205 , A61B2017/12063
摘要： A solid embolic material that is capable of filling irregularly shaped and asymmetrical vascular defects in a controlled and predictable manner, without the difficulties associated with delivery of the embolic material through a microcatheter and containment of the embolic material in a defect. A detachable embolic balloon with optional check valve for maintaining liquid in the balloon prior to curing and optional multi-leaflet covering to prevent the balloon from expanding into the native vascular lumen.
摘要翻译：一种固体栓塞材料，其能够以受控和可预测的方式填充不规则形状和不对称的血管缺陷，而不需要通过微导管输送栓塞材料并将栓塞材料容纳在缺陷中。一种可拆卸的栓塞气囊，其具有可选的止回阀，用于在固化之前保持气囊中的液体，并且可选的多叶片覆盖物以防止气囊扩张到天然血管腔中。

20. 发明申请

WO2003094805A2 TACTICAL DETACHABLE ANATOMIC CONTAINMENT DEVICE AND THERAPEUTIC TREATMENT SYSTEM 审中-公开
标题翻译：战术可拆卸解剖装置和治疗系统
公开(公告)号：WO2003094805A2
公开(公告)日：2003-11-20
申请号：PCT/US2003/013197
申请日：2003-04-28
申请人： SCIMED LIFE SYSTEMS, INC.
发明人： OLSON JR., Stanley, W. , JANSEN, Lex, P. , BURNS, Michael
IPC分类号： A61F2/44
CPC分类号： A61B17/7097 , A61B17/12027 , A61B17/1204 , A61B17/12099 , A61B17/12136 , A61B17/12172 , A61B17/7098 , A61B2017/1205 , A61B2017/12063 , A61B2017/22051
摘要： Devices and methods for the controlled delivery of therapeutic agents into bone and soft tissue to prevent the unintentional migration of therapeutic agents from the treatment site. The containment device can be made of a fabric or membrane that is porous, semi-porous, non-porous, bio-resorbable, or non-resorbable materials. A containment device is advanced to the interior of the target structure and filled with a therapeutic agent. The containment device may be permanently or temporarily implanted. Where permanent implantation is desired, the containment device may be detached via a severable junction.
摘要翻译：用于将治疗剂控制递送到骨和软组织中以防止治疗剂从治疗部位意外迁移的装置和方法。容纳装置可以由多孔，半多孔，无孔，生物可吸收或不可再吸收材料的织物或膜制成。容纳装置前进到目标结构的内部并填充有治疗剂。容纳装置可以永久地或临时植入。在需要永久性植入的情况下，容纳装置可以通过可分离的连接部分离。

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