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11. 发明申请

WO2008104977A2 TISSUE-CHARACTERIZATION SYSTEM AND METHOD 审中-公开
标题翻译：组织表征系统和方法
公开(公告)号：WO2008104977A2
公开(公告)日：2008-09-04
申请号：PCT/IL2008/000247
申请日：2008-02-27
申请人： DUNE MEDICAL DEVICES LTD. , HASHIMSHONY, Dan , AHARONOWITZ, Gal , COHEN, Gil , GELTNER, Iddo
发明人： HASHIMSHONY, Dan , AHARONOWITZ, Gal , COHEN, Gil , GELTNER, Iddo
IPC分类号： A61B5/00
CPC分类号： A61B5/0059 , A61B5/0064 , A61B5/05 , A61B5/6834
摘要： A measurement system and method are provided for use in characterizing a tissue. The system comprises a probe adapted for operating in either a scan mode or a measure mode, and a control unit for operating the probe. The probe comprises a sensing module for measuring one or more parameters indicative of one or more states of the tissue; and an attachment module configured and operable to enable selective operation of the probe in either one of the scan mode and the measure modes. The control unit is configured and operative to selectively operate the probe in either one of the scan and measure modes.
摘要翻译：提供了用于表征组织的测量系统和方法。该系统包括适合于在扫描模式或测量模式下操作的探针以及用于操作探针的控制单元。探针包括用于测量指示组织的一个或多个状态的一个或多个参数的感测模块; 以及附件模块，其被配置并且可操作以使得能够在所述扫描模式和所述测量模式中的任一者中选择性操作所述探针。控制单元被配置和操作以选择性地在扫描和测量模式中的任一模式下操作探针。

12. 发明申请

WO2005009200A2 METHOD AND APPARATUS FOR EXAMINING A SUBSTANCE,PARTICULARLY TISSUE, TO CHARACTERIZE ITS TYPE 审中-公开
标题翻译：用于检查物质，特别是组织的特征类型的方法和装置
公开(公告)号：WO2005009200A2
公开(公告)日：2005-02-03
申请号：PCT/IL2004/000641
申请日：2004-07-15
申请人： DUNE MEDICAL DEVICES LTD. , HASHIMSHONY, Dan , COHEN, Gil
发明人： HASHIMSHONY, Dan , COHEN, Gil
IPC分类号： A61B
CPC分类号： G01R33/60 , A61B5/053 , A61B5/055 , A61B10/0266 , A61B90/39 , G01R33/3808
摘要： A method and apparatus for examining a substance volume to characterize its type, particularly useful for examining tissue to characterize it as cancerous or non-cancerous , by: applying a polarizing magnetic field through the examined substance: applying RF pulses locally to the examined substance volume such as to invoke electrical impedance (EI) responses signals corresponding to the electrical impedance of the substance, and magnetic resonance (MR) responses signals corresponding to the MR properties of the substance; detecting the EI and MR response signals; and utilizing the detected response signals for characterizing the examined substance volume type.
摘要翻译：一种用于检查物质体积以表征其类型的方法和装置，特别用于通过以下方式检查组织以将其表征为癌性或非癌性：通过检查的物质施加极化磁场：将RF脉冲局部施加到被检物质体积例如调用对应于物质的电阻抗的电阻抗（EI）响应信号，以及对应于物质的MR性质的磁共振（MR）响应信号; 检测EI和MR响应信号; 以及利用检测到的响应信号来表征所检查的物质体积类型。

13. 发明申请

WO2005011754A1 METHOD FOR ENERGY COUPLING ESPECIALLY USEFUL FOR DISINFECTING, AND VARIOUS SYSTEMS USING IT 审中-公开
标题翻译：能够有效地消毒的能量耦合方法以及使用它的各种系统
公开(公告)号：WO2005011754A1
公开(公告)日：2005-02-10
申请号：PCT/IL2004/000718
申请日：2004-08-04
申请人： ATLANTIUM LASERS LIMITED , TRIBELSKY, Zamir , RABANI, Joseph , NAVON, Mordechai , COHEN, Gil
发明人： TRIBELSKY, Zamir , RABANI, Joseph , NAVON, Mordechai , COHEN, Gil
IPC分类号： A61L2/10
CPC分类号： A61L9/205 , A61L2/10 , A61L2/183 , C02F1/32 , C02F1/34
摘要： Method and system are disclosed for coupling energy from at least on energy source, e.g. UV light source, ultrasonic transducer, or combination thereof, to a target site, e.g. hazardous bacteria, through a streaming liquid, e.g. water. The bacteria toward which energy is to be coupled could be present in the water stream itself and/or on a surface toward which the water stream is to be launched at the end of its flow. Accordingly, in-line aseptic filling is provided, which can fill and simultaneously disinfect a container. According to another embodiment where the water is used for washing, in-line aseptic washing device is provided. A variety of other embodiments is disclosed as well.
摘要翻译：公开了用于耦合至少在能量源上的能量的方法和系统，例如， UV光源，超声波换能器或其组合，到目标部位，例如，有害细菌，通过流动液体，例如，水。能量耦合的细菌可以存在于水流本身和/或水流在其流动结束时将被发射的表面上。因此，提供了可以填充并同时消毒容器的在线无菌填充物。根据其中水用于清洗的另一实施例，提供了在线无菌洗涤装置。还公开了各种其它实施例。

14. 发明申请

WO2011016035A1 ELECTROMAGNETIC SENSOR FOR USE IN MEASUREMENTS ON A SUBJECT 审中-公开
标题翻译：电磁传感器用于测量一个主体
公开(公告)号：WO2011016035A1
公开(公告)日：2011-02-10
申请号：PCT/IL2010/000630
申请日：2010-08-03
申请人： DUNE MEDICAL DEVICES LTD. , COHEN, Gil , HASHIMSHONY, Dan , GELTNER, Iddo , GOLOMBEK, Harel
发明人： COHEN, Gil , HASHIMSHONY, Dan , GELTNER, Iddo , GOLOMBEK, Harel
IPC分类号： A61B5/05
CPC分类号： A61B5/053 , A61B5/05 , A61B2560/04 , A61B2562/0209 , A61B2562/046 , A61B2562/227
摘要： A sensor unit for use in measurements on a subject is presented. The sensor unit includes a near field electromagnetic sensor and a flexible signal transmission structure, which are integral with one another by means of at least one common continuous surface. The flexible signal transmission structure is constructed from a first layer including signal connection lines associated with sensor cells near field electromagnetic sensor and a second electrically conductive layer electrically coupled to the electrically conductive material of the sensor.
摘要翻译：介绍了一种用于测量对象的传感器单元。传感器单元包括通过至少一个公共连续表面彼此成一体的近场电磁传感器和柔性信号传输结构。柔性信号传输结构由包括与传感器单元近场电磁传感器相关联的信号连接线的第一层和与传感器的导电材料电耦合的第二导电层构成。

15. 发明申请

WO2009156982A2 RF CALIBRATION DEVICE AND METHOD 审中-公开
标题翻译：射频校准装置和方法
公开(公告)号：WO2009156982A2
公开(公告)日：2009-12-30
申请号：PCT/IL2009/000611
申请日：2009-06-18
申请人： DUNE MEDICAL DEVICES LTD. , HASHIMSHONY, Dan , COHEN, Gil , GELTNER, Iddo
发明人： HASHIMSHONY, Dan , COHEN, Gil , GELTNER, Iddo
IPC分类号： G01R35/00
CPC分类号： G01R27/32 , G01R35/007
摘要： A measurement device is presented being configured to be connectable to an analyzer unit (comprising a network analyzer) via at least one RF port connection. The measurement device comprises at least one measuring unit and at least one calibration and control unit connected to and integral with said at least one measuring unit. The calibration and control unit is configured to enable connection of the at least one measuring unit to the analyzer unit. The calibration and control unit comprises a number of terminals associated with a plurality of calibration loads of known RF reflection coefficients respectively and comprises a memory utility carrying recorded data indicative of said RF reflection coefficients and recorded data indicative of RF transfer coefficients of the calibration and control unit. This configuration enables calculation of the RF response of each of said at least one measuring unit while remaining integral with the calibration and control unit.
摘要翻译：呈现经由至少一个RF端口连接可连接到分析器单元（包括网络分析器）的测量装置。测量装置包括至少一个测量单元和连接到所述至少一个测量单元并与所述至少一个测量单元一体的至少一个校准和控制单元。校准和控制单元被配置为使得能够将至少一个测量单元连接到分析器单元。校准和控制单元分别包括与已知RF反射系数的多个校准负载相关联的多个终端，并且包括存储器实用工具，其承载表示所述RF反射系数的记录数据和指示校准和控制的RF传输系数的记录数据单元。该配置使得能够计算所述至少一个测量单元中的每一个的RF响应，同时与校准和控制单元保持一体。

16. 发明申请

WO2009010960A2 MEDICAL DEVICE AND METHOD FOR USE IN TISSUE CHARACTERIZATION AND TREATMENT 审中-公开
标题翻译：医疗装置和组织特征和治疗方法
公开(公告)号：WO2009010960A2
公开(公告)日：2009-01-22
申请号：PCT/IL2008/000965
申请日：2008-07-13
申请人： DUNE MEDICAL DEVICES LTD. , HASHIMSHONY, Dan , COHEN, Gil
发明人： HASHIMSHONY, Dan , COHEN, Gil
IPC分类号： A61B10/02 , A61B17/00 , A61B5/00 , A61B19/00
CPC分类号： A61B10/0233 , A61B5/00 , A61B10/0266 , A61B90/37 , A61B2017/00022 , A61B2017/00128 , A61B2017/00199 , A61B2018/1475 , A61B2090/061
摘要： A medical device is presented for use in tissue characterization and treatment. The device comprises: a tissue characterization probe comprising an elongated carrier for carrying an array of tissue characterization sensors arranged in a spaced-apart relationship at least along an axis of said carrier, such that progression of the probe through a tissue mass provides for locating and determining a dimension of an abnormal tissue specimen inside said tissue mass based on characterization signals from the sensors in the array, thereby enabling consequent treatment of the abnormal tissue specimen by a treatment tool.
摘要翻译：呈现用于组织表征和治疗的医疗装置。该装置包括：组织表征探针，其包括细长载体，用于承载至少沿所述载体的轴线以间隔关系布置的组织表征传感器阵列，使得探针通过组织块的进展提供定位和基于来自阵列中的传感器的表征信号，确定所述组织块内部的异常组织标本的尺寸，由此由治疗工具进行异常组织标本的治疗。

17. 发明申请

WO2005089065A2 CLEAN MARGIN ASSESSMENT TOOL 审中-公开
标题翻译：清洁评估工具
公开(公告)号：WO2005089065A2
公开(公告)日：2005-09-29
申请号：PCT/IL2005/000330
申请日：2005-03-23
申请人： DUNE MEDICAL DEVICES LTD. , HASHIMSHONY, Dan , COHEN, Gil , GELTNER, Iddo
发明人： HASHIMSHONY, Dan , COHEN, Gil , GELTNER, Iddo
IPC分类号： A61B5/00 , A61B5/05 , A61B5/053 , A61B5/055 , A61B5/06 , A61B8/08 , A61B8/12 , A61B17/00 , A61B18/08 , A61B19/00
CPC分类号： A61B5/415 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/0086 , A61B5/0091 , A61B5/01 , A61B5/015 , A61B5/0507 , A61B5/053 , A61B5/055 , A61B5/06 , A61B5/4312 , A61B8/0858 , A61B8/12 , A61B8/4245 , A61B8/4472 , A61B18/082 , A61B34/20 , A61B2017/00026 , A61B2034/107 , A61B2034/2051 , A61B2034/2055 , A61B2090/061 , A61B2090/367 , A61B2090/378
摘要： An integrated tool is provided, having a tissue-type sensor, for determining the tissue type at a near zone volume of a tissue surface, and a distance-measuring sensor, for determining the distance to an interface with another tissue type, for (i) confirming an existence of a clean margin of healthy tissue around a malignant tumor, which is being removed, and (ii) determining the depth of the clean margin. The integrated tool may further include a position tracking device and an incision instrument. The soft tissue may be held within a fixed frame, while the tumor is being removed. Additionally a method for malignant tumor removal is provided, comprising, fixing the soft tissue within a frame, performing imaging with the hand-held, integrated tool, from a plurality of locations and orientations around the soft tissue, reconstructing a three-dimensional image of the soft tissue and the tumor within, defining a desired clean margin on the reconstructed image, calculating a recommended incision path, displaying the recommended path on the reconstructed image, and cutting the tissue while determining its type, at the near zone volume of the incision surface. The method may further include continuously imaging with the cutting, continuously correcting the reconstructed image and the recommended incision path, and continuously determining the tissue type, at the near zone volume of the incision surface.
摘要翻译：提供了一种集成工具，具有用于确定组织表面的近区域体积处的组织类型的组织型传感器和用于确定与另一组织类型的界面的距离的距离测量传感器，用于（i ）确认正在被去除的恶性肿瘤周围存在健康组织的清洁边缘，以及（ii）确定清洁边缘的深度。集成工具还可以包括位置跟踪装置和切口装置。当肿瘤被移除时，软组织可以保持在固定框架内。另外，提供了一种用于恶性肿瘤去除的方法，包括：将软组织固定在框架内，利用手持式集成工具从软组织周围的多个位置和取向进行成像，重建三维图像软组织和肿瘤内，在重建图像上限定所需的清洁边缘，计算推荐切口路径，在重建图像上显示推荐路径，以及在确定其类型的同时切割组织，在切口的近区域处表面。该方法可以进一步包括连续成像切割，连续校正重建图像和推荐切口路径，以及在切口表面的近区域体积处连续地确定组织类型。

18. 发明申请

WO2002071133A3 FIBER OPTICAL ATTENUATOR 审中-公开
公开(公告)号：WO2002071133A3
公开(公告)日：2002-09-12
申请号：PCT/IL2002/000188
申请日：2002-03-08
申请人： XTELLUS INC. , COHEN, Gil
发明人： COHEN, Gil
IPC分类号： G02F1/01
摘要： A fiber optical attenuator utilizing the cut-off phenomenon for single mode propagation of an optical wave down a single mode fiber, comprising an element such as a pixelated liquid crystal element, capable of spatially changing the phase across the cross section of an input optical signal. Such a spatial phase change is equivalent to a change in the mode structure of the propagating wave. The signal propagating in the single mode output fiber is attenuated in accordance with the extent to which higher order modes are mixed into the low order mode originally present. When the mode is completely transformed to higher order modes, the wave is effectively completely blocked from entering the output single-mode fiber, and the attenuation is high. The level of attenuation is determined by the fraction of the wave which is converted to modes other than the lowest order mode, and is thus controllable by the voltage applied to the pixels of the liquid crystal element.

19. 发明申请

WO2012164567A1 TISSUE SAMPLING FOR PATHOLOGICAL STUDY 审中-公开
标题翻译：组织采集的病理学研究
公开(公告)号：WO2012164567A1
公开(公告)日：2012-12-06
申请号：PCT/IL2012/050196
申请日：2012-06-03
申请人： DUNE MEDICAL DEVICES LTD. , HASHIMSHONY, Dan , COHEN, Gil
发明人： HASHIMSHONY, Dan , COHEN, Gil
IPC分类号： A61B5/01 , A61B10/00
CPC分类号： G01N33/4833 , A61B10/00 , A61B10/02 , A61B2034/107 , G01N1/06 , G01N1/286 , G16H40/63
摘要： A probe device for use in a tissue inspection system is presented. The probe device comprises a probe body and a control unit at least partially incorporated in the probe body. The probe body carries at least a tissue characterization unit operable for providing sensing data indicative of at least one tissue property at measurement locations in the tissue portion being held by the probe. The control unit comprises: a processor utility for receiving and processing the sensing data and generating measured data indicative of a spatial profile of said at least one tissue property distribution within the tissue portion, and comprises at least one of the following: an imaging utility for receiving said measured data and generating and displaying an image indicative thereof thereby enabling a user to select a region of said tissue portion for further analysis; and a pattern generator module configured for receiving and analyzing said measured data and determining a pattern indicative of an arrangement of regions in said tissue portion, thereby enabling selection of at least one of the regions for further analysis.
摘要翻译：提出了一种用于组织检测系统的探针装置。探针装置包括探针体和至少部分地结合在探针体内的控制单元。探针体携带至少一个组织表征单元，其可操作用于提供感测数据，该感测数据指示由探针保持的组织部分中的测量位置处的至少一个组织属性。所述控制单元包括：处理器实用程序，用于接收和处理所述感测数据并产生指示所述组织部分内的所述至少一个组织属性分布的空间分布的测量数据，并且包括以下中的至少一个：用于接收所述测量数据并产生和显示指示其的图像，从而使用户能够选择所述组织部分的区域用于进一步分析; 以及图案生成器模块，被配置为接收和分析所述测量数据并且确定指示所述组织部分中的区域布置的图案，由此能够选择所述区域中的至少一个用于进一步分析。

20. 发明申请

WO2011016034A2 SURGICAL TOOL 审中-公开
标题翻译：手术工具
公开(公告)号：WO2011016034A2
公开(公告)日：2011-02-10
申请号：PCT/IL2010/000629
申请日：2010-08-03
申请人： DUNE MEDICAL DEVICES LTD. , HASHIMSHONY, Dan , COHEN, Gil
发明人： HASHIMSHONY, Dan , COHEN, Gil
IPC分类号： A61B17/34
CPC分类号： A61B10/0266 , A61B5/05 , A61B5/0538 , A61B10/0275 , A61B10/06 , A61B2505/05 , A61B2562/227
摘要： A surgical tool for use in a tissue removal procedure from a subject is described. The surgical tool has proximal and distal regions and at least one sensor for sensing one or more predetermined conditions located at a distal region of the surgical tool. And a substantially flat signal transmission structure electrically connected with the at least one sensor and extending between the location at the distal region and the proximal region. The signal transmission structure is configured for providing impedance controlled signal transmission between the at least one sensor and the proximal region.
摘要翻译：描述了用于来自受试者的组织去除程序的外科手术工具。外科手术工具具有近端和远端区域和至少一个传感器，用于感测位于手术工具的远端区域的一个或多个预定条件。以及基本上平坦的信号传输结构，其与所述至少一个传感器电连接并且在远端区域和近侧区域之间的位置之间延伸。信号传输结构被配置为在至少一个传感器和近端区域之间提供阻抗控制的信号传输。

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