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1. 发明申请

WO2008104977A2 TISSUE-CHARACTERIZATION SYSTEM AND METHOD 审中-公开
标题翻译：组织表征系统和方法
公开(公告)号：WO2008104977A2
公开(公告)日：2008-09-04
申请号：PCT/IL2008/000247
申请日：2008-02-27
申请人： DUNE MEDICAL DEVICES LTD. , HASHIMSHONY, Dan , AHARONOWITZ, Gal , COHEN, Gil , GELTNER, Iddo
发明人： HASHIMSHONY, Dan , AHARONOWITZ, Gal , COHEN, Gil , GELTNER, Iddo
IPC分类号： A61B5/00
CPC分类号： A61B5/0059 , A61B5/0064 , A61B5/05 , A61B5/6834
摘要： A measurement system and method are provided for use in characterizing a tissue. The system comprises a probe adapted for operating in either a scan mode or a measure mode, and a control unit for operating the probe. The probe comprises a sensing module for measuring one or more parameters indicative of one or more states of the tissue; and an attachment module configured and operable to enable selective operation of the probe in either one of the scan mode and the measure modes. The control unit is configured and operative to selectively operate the probe in either one of the scan and measure modes.
摘要翻译：提供了用于表征组织的测量系统和方法。该系统包括适合于在扫描模式或测量模式下操作的探针以及用于操作探针的控制单元。探针包括用于测量指示组织的一个或多个状态的一个或多个参数的感测模块; 以及附件模块，其被配置并且可操作以使得能够在所述扫描模式和所述测量模式中的任一者中选择性操作所述探针。控制单元被配置和操作以选择性地在扫描和测量模式中的任一模式下操作探针。

2. 发明申请

WO2005009200A2 METHOD AND APPARATUS FOR EXAMINING A SUBSTANCE,PARTICULARLY TISSUE, TO CHARACTERIZE ITS TYPE 审中-公开
标题翻译：用于检查物质，特别是组织的特征类型的方法和装置
公开(公告)号：WO2005009200A2
公开(公告)日：2005-02-03
申请号：PCT/IL2004/000641
申请日：2004-07-15
申请人： DUNE MEDICAL DEVICES LTD. , HASHIMSHONY, Dan , COHEN, Gil
发明人： HASHIMSHONY, Dan , COHEN, Gil
IPC分类号： A61B
CPC分类号： G01R33/60 , A61B5/053 , A61B5/055 , A61B10/0266 , A61B90/39 , G01R33/3808
摘要： A method and apparatus for examining a substance volume to characterize its type, particularly useful for examining tissue to characterize it as cancerous or non-cancerous , by: applying a polarizing magnetic field through the examined substance: applying RF pulses locally to the examined substance volume such as to invoke electrical impedance (EI) responses signals corresponding to the electrical impedance of the substance, and magnetic resonance (MR) responses signals corresponding to the MR properties of the substance; detecting the EI and MR response signals; and utilizing the detected response signals for characterizing the examined substance volume type.
摘要翻译：一种用于检查物质体积以表征其类型的方法和装置，特别用于通过以下方式检查组织以将其表征为癌性或非癌性：通过检查的物质施加极化磁场：将RF脉冲局部施加到被检物质体积例如调用对应于物质的电阻抗的电阻抗（EI）响应信号，以及对应于物质的MR性质的磁共振（MR）响应信号; 检测EI和MR响应信号; 以及利用检测到的响应信号来表征所检查的物质体积类型。

3. 发明申请

WO2011016035A1 ELECTROMAGNETIC SENSOR FOR USE IN MEASUREMENTS ON A SUBJECT 审中-公开
标题翻译：电磁传感器用于测量一个主体
公开(公告)号：WO2011016035A1
公开(公告)日：2011-02-10
申请号：PCT/IL2010/000630
申请日：2010-08-03
申请人： DUNE MEDICAL DEVICES LTD. , COHEN, Gil , HASHIMSHONY, Dan , GELTNER, Iddo , GOLOMBEK, Harel
发明人： COHEN, Gil , HASHIMSHONY, Dan , GELTNER, Iddo , GOLOMBEK, Harel
IPC分类号： A61B5/05
CPC分类号： A61B5/053 , A61B5/05 , A61B2560/04 , A61B2562/0209 , A61B2562/046 , A61B2562/227
摘要： A sensor unit for use in measurements on a subject is presented. The sensor unit includes a near field electromagnetic sensor and a flexible signal transmission structure, which are integral with one another by means of at least one common continuous surface. The flexible signal transmission structure is constructed from a first layer including signal connection lines associated with sensor cells near field electromagnetic sensor and a second electrically conductive layer electrically coupled to the electrically conductive material of the sensor.
摘要翻译：介绍了一种用于测量对象的传感器单元。传感器单元包括通过至少一个公共连续表面彼此成一体的近场电磁传感器和柔性信号传输结构。柔性信号传输结构由包括与传感器单元近场电磁传感器相关联的信号连接线的第一层和与传感器的导电材料电耦合的第二导电层构成。

4. 发明申请

WO2009156982A2 RF CALIBRATION DEVICE AND METHOD 审中-公开
标题翻译：射频校准装置和方法
公开(公告)号：WO2009156982A2
公开(公告)日：2009-12-30
申请号：PCT/IL2009/000611
申请日：2009-06-18
申请人： DUNE MEDICAL DEVICES LTD. , HASHIMSHONY, Dan , COHEN, Gil , GELTNER, Iddo
发明人： HASHIMSHONY, Dan , COHEN, Gil , GELTNER, Iddo
IPC分类号： G01R35/00
CPC分类号： G01R27/32 , G01R35/007
摘要： A measurement device is presented being configured to be connectable to an analyzer unit (comprising a network analyzer) via at least one RF port connection. The measurement device comprises at least one measuring unit and at least one calibration and control unit connected to and integral with said at least one measuring unit. The calibration and control unit is configured to enable connection of the at least one measuring unit to the analyzer unit. The calibration and control unit comprises a number of terminals associated with a plurality of calibration loads of known RF reflection coefficients respectively and comprises a memory utility carrying recorded data indicative of said RF reflection coefficients and recorded data indicative of RF transfer coefficients of the calibration and control unit. This configuration enables calculation of the RF response of each of said at least one measuring unit while remaining integral with the calibration and control unit.
摘要翻译：呈现经由至少一个RF端口连接可连接到分析器单元（包括网络分析器）的测量装置。测量装置包括至少一个测量单元和连接到所述至少一个测量单元并与所述至少一个测量单元一体的至少一个校准和控制单元。校准和控制单元被配置为使得能够将至少一个测量单元连接到分析器单元。校准和控制单元分别包括与已知RF反射系数的多个校准负载相关联的多个终端，并且包括存储器实用工具，其承载表示所述RF反射系数的记录数据和指示校准和控制的RF传输系数的记录数据单元。该配置使得能够计算所述至少一个测量单元中的每一个的RF响应，同时与校准和控制单元保持一体。

5. 发明申请

WO2009010960A2 MEDICAL DEVICE AND METHOD FOR USE IN TISSUE CHARACTERIZATION AND TREATMENT 审中-公开
标题翻译：医疗装置和组织特征和治疗方法
公开(公告)号：WO2009010960A2
公开(公告)日：2009-01-22
申请号：PCT/IL2008/000965
申请日：2008-07-13
申请人： DUNE MEDICAL DEVICES LTD. , HASHIMSHONY, Dan , COHEN, Gil
发明人： HASHIMSHONY, Dan , COHEN, Gil
IPC分类号： A61B10/02 , A61B17/00 , A61B5/00 , A61B19/00
CPC分类号： A61B10/0233 , A61B5/00 , A61B10/0266 , A61B90/37 , A61B2017/00022 , A61B2017/00128 , A61B2017/00199 , A61B2018/1475 , A61B2090/061
摘要： A medical device is presented for use in tissue characterization and treatment. The device comprises: a tissue characterization probe comprising an elongated carrier for carrying an array of tissue characterization sensors arranged in a spaced-apart relationship at least along an axis of said carrier, such that progression of the probe through a tissue mass provides for locating and determining a dimension of an abnormal tissue specimen inside said tissue mass based on characterization signals from the sensors in the array, thereby enabling consequent treatment of the abnormal tissue specimen by a treatment tool.
摘要翻译：呈现用于组织表征和治疗的医疗装置。该装置包括：组织表征探针，其包括细长载体，用于承载至少沿所述载体的轴线以间隔关系布置的组织表征传感器阵列，使得探针通过组织块的进展提供定位和基于来自阵列中的传感器的表征信号，确定所述组织块内部的异常组织标本的尺寸，由此由治疗工具进行异常组织标本的治疗。

6. 发明申请

WO2005089065A2 CLEAN MARGIN ASSESSMENT TOOL 审中-公开
标题翻译：清洁评估工具
公开(公告)号：WO2005089065A2
公开(公告)日：2005-09-29
申请号：PCT/IL2005/000330
申请日：2005-03-23
申请人： DUNE MEDICAL DEVICES LTD. , HASHIMSHONY, Dan , COHEN, Gil , GELTNER, Iddo
发明人： HASHIMSHONY, Dan , COHEN, Gil , GELTNER, Iddo
IPC分类号： A61B5/00 , A61B5/05 , A61B5/053 , A61B5/055 , A61B5/06 , A61B8/08 , A61B8/12 , A61B17/00 , A61B18/08 , A61B19/00
CPC分类号： A61B5/415 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/0086 , A61B5/0091 , A61B5/01 , A61B5/015 , A61B5/0507 , A61B5/053 , A61B5/055 , A61B5/06 , A61B5/4312 , A61B8/0858 , A61B8/12 , A61B8/4245 , A61B8/4472 , A61B18/082 , A61B34/20 , A61B2017/00026 , A61B2034/107 , A61B2034/2051 , A61B2034/2055 , A61B2090/061 , A61B2090/367 , A61B2090/378
摘要： An integrated tool is provided, having a tissue-type sensor, for determining the tissue type at a near zone volume of a tissue surface, and a distance-measuring sensor, for determining the distance to an interface with another tissue type, for (i) confirming an existence of a clean margin of healthy tissue around a malignant tumor, which is being removed, and (ii) determining the depth of the clean margin. The integrated tool may further include a position tracking device and an incision instrument. The soft tissue may be held within a fixed frame, while the tumor is being removed. Additionally a method for malignant tumor removal is provided, comprising, fixing the soft tissue within a frame, performing imaging with the hand-held, integrated tool, from a plurality of locations and orientations around the soft tissue, reconstructing a three-dimensional image of the soft tissue and the tumor within, defining a desired clean margin on the reconstructed image, calculating a recommended incision path, displaying the recommended path on the reconstructed image, and cutting the tissue while determining its type, at the near zone volume of the incision surface. The method may further include continuously imaging with the cutting, continuously correcting the reconstructed image and the recommended incision path, and continuously determining the tissue type, at the near zone volume of the incision surface.
摘要翻译：提供了一种集成工具，具有用于确定组织表面的近区域体积处的组织类型的组织型传感器和用于确定与另一组织类型的界面的距离的距离测量传感器，用于（i ）确认正在被去除的恶性肿瘤周围存在健康组织的清洁边缘，以及（ii）确定清洁边缘的深度。集成工具还可以包括位置跟踪装置和切口装置。当肿瘤被移除时，软组织可以保持在固定框架内。另外，提供了一种用于恶性肿瘤去除的方法，包括：将软组织固定在框架内，利用手持式集成工具从软组织周围的多个位置和取向进行成像，重建三维图像软组织和肿瘤内，在重建图像上限定所需的清洁边缘，计算推荐切口路径，在重建图像上显示推荐路径，以及在确定其类型的同时切割组织，在切口的近区域处表面。该方法可以进一步包括连续成像切割，连续校正重建图像和推荐切口路径，以及在切口表面的近区域体积处连续地确定组织类型。

7. 发明申请

WO2009150647A2 DOUBLE REGISTRATION 审中-公开
标题翻译：双重登记
公开(公告)号：WO2009150647A2
公开(公告)日：2009-12-17
申请号：PCT/IL2009/000577
申请日：2009-06-10
申请人： DUNE MEDICAL DEVICES LTD. , COHEN, Gil , HASHIMSHONY, Dan
发明人： COHEN, Gil , HASHIMSHONY, Dan
IPC分类号： A61B19/00
CPC分类号： A61B19/5244 , A61B34/20 , A61B2034/2068 , A61B2034/2072 , A61B2090/363 , A61B2090/3908
摘要： A mapping system including: (a) at least one external marker adapted for positioning outside a target to define a target context; (b) at least one target marker adapted for positioning with the target; (c) a data acquisition tool configured to provide position coordinates for at least one data point at the target; and (d) a registration module adapted to output position coordinates of said at least one data point relative to at least a portion of the target context.
摘要翻译：一种映射系统，包括：（a）适于定位在目标外部以定义目标上下文的至少一个外部标记; （b）适于与靶标定位的至少一个目标标记; （c）数据采集工具，被配置为提供所述目标处的至少一个数据点的位置坐标; 以及（d）注册模块，其适于相对于所述目标上下文的至少一部分输出所述至少一个数据点的位置坐标。

8. 发明申请

WO2008132750A1 CLEAN MARGIN ASSESSMENT TOOL 审中-公开
标题翻译：清洁评估工具
公开(公告)号：WO2008132750A1
公开(公告)日：2008-11-06
申请号：PCT/IL2008/000594
申请日：2008-05-01
申请人： DUNE MEDICAL DEVICES LTD. , HASHIMSHONY, Dan , COHEN, Gil , GELTNER, Iddo
发明人： HASHIMSHONY, Dan , COHEN, Gil , GELTNER, Iddo
IPC分类号： A61B5/05 , A61B8/08 , A61B5/00 , A61B5/053 , A61B5/055 , A61B5/06 , A61B8/12
CPC分类号： A61B5/0507 , A61B5/0062 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/0086 , A61B5/0091 , A61B5/015 , A61B5/053 , A61B5/055 , A61B5/065 , A61B5/415 , A61B5/4312 , A61B5/4381 , A61B8/4245
摘要： A device is provided for use in monitoring a tissue. The device is configured for holding and characterizing a tissue portion during the monitoring. The device comprises a housing configured for receiving and holding the tissue portion by an inner side or an outer side of the housing; and a tissue-type sensor unit mounted on either one or both of the inner and outer sides of the housing and configured and operable for characterizing the tissue portion being held by the housing.
摘要翻译：提供了一种用于监测组织的装置。该装置被配置为在监视期间保持和表征组织部分。该装置包括构造成用于通过壳体的内侧或外侧容纳和保持组织部分的壳体; 以及组装型传感器单元，其安装在所述壳体的内侧和外侧的一侧或两侧，并被构造和可操作以表征由所述壳体保持的所述组织部分。

9. 发明申请

WO2008132714A2 ERGONOMIC PROBES 审中-公开
标题翻译：人格探索
公开(公告)号：WO2008132714A2
公开(公告)日：2008-11-06
申请号：PCT/IL2008/000406
申请日：2008-03-24
申请人： DUNE MEDICAL DEVICES LTD. , HASHIMSHONY, Dan , COHEN, Gil , GELTNER, Iddo
发明人： HASHIMSHONY, Dan , COHEN, Gil , GELTNER, Iddo
IPC分类号： A61B5/00 , B25G3/38 , A61B6/00 , A61B8/00 , A61B19/00
CPC分类号： A61B5/4312 , A61B5/00 , A61B5/0055 , A61B5/0059 , A61B5/01 , A61B5/053 , A61B5/055 , A61B5/444 , A61B5/445 , A61B6/00 , A61B6/037 , A61B6/4417 , A61B8/00 , A61B8/12 , A61B8/445 , A61B8/4455 , A61B90/30 , A61B2090/395 , A61B2560/0425 , B25G1/06 , B25G1/102
摘要： An ergonomic device for intraoperative tissue characterization is provided, having a gripping handle and a sensor head, arranged with an angle alpha between them, wherein in absolute value, alpha > 10 degrees, and alpha may be adjusted in one, two, or three planes. The device may further comprise a light fixture, configured for lighting the tissue, as it is characterized, a marking module, configured for marking the tissue, as it is characterized, a vacuum system, for improved contact between a sensing surface and the tissue, and a transparent frame, which enables an operator to observe the tissue, as it is characterized. The device may be operative with at least one sensor, selected from the group consisting of an optical sensor, an X-ray sensor, an RF sensor, a MW sensor, an infrared thermography sensor, an ultrasound sensor, an MR sensor, an impedance sensor, a temperature sensor, a biosensor, a chemical sensor, a radioactive-emission sensor, a nonirradiative RF sensor, and a mechanical sensor.
摘要翻译：提供了一种用于术中组织表征的符合人体工程学的装置，其具有夹紧手柄和传感器头部，其间以它们之间的角度α布置，其中绝对值为α> 10度，并且可以在一个，两个或三个平面中调整α 。该装置可进一步包括配置用于照亮组织的灯具，其特征在于，标记模块被构造成用于标记组织，其特征在于，真空系统用于改善感测表面和组织之间的接触，以及透明框架，其使得操作者能够观察组织的特征。该装置可以与至少一个传感器一起操作，该传感器选自光学传感器，X射线传感器，RF传感器，MW传感器，红外热像传感器，超声波传感器，MR传感器，阻抗传感器，温度传感器，生物传感器，化学传感器，放射性发射传感器，非辐射RF传感器和机械传感器。

10. 发明申请

WO2008072238A2 GRAPHICAL USER INTERFACES (GUI), METHODS AND APPARATUS FOR DATA PRESENTATION 审中-公开
标题翻译：图形用户界面（GUI），数据呈现的方法和装置
公开(公告)号：WO2008072238A2
公开(公告)日：2008-06-19
申请号：PCT/IL2007/001539
申请日：2007-12-12
申请人： DUNE MEDICAL DEVICES LTD. , HASHIMSHONY, Dan , YARDEN, Orit , AHARONOWITZ, Gal , COHEN, Gil
发明人： HASHIMSHONY, Dan , YARDEN, Orit , AHARONOWITZ, Gal , COHEN, Gil
IPC分类号： G06F19/00
CPC分类号： G06F19/321 , G06F19/00 , G16H10/20
摘要： A graphical user interface (GUI) including: (a) a group definition module adapted to accept a user input defining groups; (b) a data receiver operable to receive a plurality of individual measurement input datum indicative of status of a substrate; (c) a grouping module configured to assign each of said individual measurement input datum to one of said groups to produce grouped data; and (d) an output module adapted to output the grouped data.
摘要翻译：一种图形用户界面（GUI），包括：（a）适合于接受定义组的用户输入的组定义模块; （b）数据接收器，用于接收指示衬底状态的多个单独的测量输入数据; （c）分组模块，其被配置为将每个所述个体测量输入数据分配给所述组中的一个以产生分组数据; 和（d）适于输出分组数据的输出模块。

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