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    • 11. 发明申请
    • ELECTROCERAMIC/VARIANT DEVICE AND METHOD OF USE
    • 电动/变体装置及其使用方法
    • WO2004108402A1
    • 2004-12-16
    • PCT/IB2003/001964
    • 2003-06-11
    • IVANOV, Vladimir
    • IVANOV, Vladimir
    • B32B3/02
    • C04B35/00
    • The invention is in from the field of technic which electroceramic is used in. The device with electroceramic has the element made of electroceramic (1),elements made conducting energies,elements made conducting energies are connected with the element made of electroceramic. The device with electroceramic is in a frame (2). Constructive features of the claimed invention give opportunity of effective use of elements made of electroceramic. The claimed invention is simple in construction, comfortable and economical in use and doesn’t take much to be prepared for the work.
    • 本发明属于使用电陶瓷的技术领域。具有电陶瓷的器件具有由电陶瓷(1)制成的元件,导电能量元件,导电能量元件与由电陶瓷制成的元件连接。 具有电陶瓷的装置在框架(2)中。 要求保护的发明的构造特征给出了有效使用由电陶瓷制成的元件的机会。 要求保护的发明构造简单,使用舒适且经济,并且不需要为工作做好准备。
    • 14. 发明申请
    • PROTEASE INHIBITORS
    • PROTEASE抑制剂
    • WO2010034789A1
    • 2010-04-01
    • PCT/EP2009/062407
    • 2009-09-24
    • Medivir ABIVANOV, VladimirSAMUELSSON, BertilJOHANSSON, Per-OlaKAHNBERG, PiaWÄHLING, Horst
    • IVANOV, VladimirSAMUELSSON, BertilJOHANSSON, Per-OlaKAHNBERG, PiaWÄHLING, Horst
    • C07D491/048A61K31/496A61P19/00
    • C07D491/048
    • Compounds of the formula II, wherein R 3 is C 1 -C 3 alkyl or C 3 -C 6 cycloalkyl, either of which is optionally substituted with one or two methyl and/or a fluoro, trifluoromethyl or methoxy, when R 3 is C 3 -C 6 cycloalkyl it may alternatively be gem substituted with fluoro; R 4 is methyl or fluoro; m is 0, 1 or 2; E is a bond, or thiazolyl, optionally substituted with methyl or fluoro; A 1 is CH or N, A 2 is CR 6 R 7 or NR 6 , provided at least one of A 1 and A 2 comprises N; n is 0 or 1 such that the ring containing A 1 and A 2 is a saturated, nitrogen-containing ring of 5 or 6 ring atoms; R 6 is H, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 3 alkyl-O-C 1 -C 3 alkyl, or when A 2 is C, R 6 can also be C 1 -C 4 alkoxy or F; R 7 is H, C 1 -C 4 alkyl or F; or a pharmaceutically acceptable salt, N-oxide or hydrate thereof, have utility in the treatment of disorders characterized by inappropriate expression or activation of cathepsin K, such as osteoporosis, osteoarthritis, rheumatoid arthritis or bone metastases.
    • 其中R 3为C 1 -C 3烷基或C 3 -C 6环烷基,其中R 3为C 3 -C 6环烷基时,任选被一个或两个甲基和/或氟,三氟甲基或甲氧基取代, 被氟取代; R4是甲基或氟; m为0,1或2; E是任选被甲基或氟取代的键或噻唑基; A1是CH或N,A2是CR6R7或NR6,条件是A1和A2中的至少一个包括N; n为0或1,使得含有A 1和A 2的环是5或6个环原子的饱和的含氮环; R6是H,C1-C4烷基,C1-C4卤代烷基,C1-C3烷基-O-C1-C3烷基,或当A2是C时,R6也可以是C1-C4烷氧基或F; R 7为H,C 1 -C 4烷基或F; 或其药学上可接受的盐,N-氧化物或其水合物,可用于治疗组织蛋白酶K不适当表达或活化的疾病,例如骨质疏松症,骨关节炎,类风湿性关节炎或骨转移。
    • 16. 发明申请
    • CASCADED PUMP DELIVERY FOR REMOTELY PUMPED ERBIUM-DOPED FIBER AMPLIFIERS
    • 远程泵浦ERBIUM-DOPED光纤放大器的泵浦泵送
    • WO2006034562A1
    • 2006-04-06
    • PCT/CA2004/001754
    • 2004-09-28
    • MPB COMMUNICATIONS INC.PAPERNYI, SergueiKARPOV, VladimirIVANOV, VladimirCLEMENTS, Wallace
    • PAPERNYI, SergueiKARPOV, VladimirIVANOV, VladimirCLEMENTS, Wallace
    • H04B10/17
    • H04B10/291H04B10/2916
    • A method for pumping remote optically-pumped fiber amplifiers (ROPAs) in fiber­optic telecommunication systems is disclosed which uses cascaded Raman amplification to increase the maximum amount of pump power that can be delivered to the ROPA. According to the prior art, high power at the ROPA pump wavelength, λp, is launched directly into the fiber and the maximum launch power is limited by the onset of pump depletion by Raman noise and oscillations due to the high Raman gain at ~(λp +100) nm. In preferred embodiments of the present invention, a `primary' pump source of wavelength shorter than λp is launched into the delivery fiber along with two or more significantly lower-power `seed' sources, among which is included one at λp. The wavelength and power of the seed source(s) are chosen such that, when combined with the high-power primary source, a series, n, where n ≥ 2, of Raman conversions within the fiber ultimately leads to the development of high power at λp. In another embodiment, one or more of the seed sources at wavelengths shorter than λp are replaced by reflecting means to return, into the fiber, backward-travelling amplified spontaneous Raman scattered light resulting from high power in the fiber at a wavelength one Raman shift below the particular seed wavelength. In either case, the high power at λp is developed over a distributed length of the fiber, reaching its maximum some distance into the fiber and exceeding the maximum power possible at that point with the prior art.
    • 公开了一种用于在光纤通信系统中泵送远程光泵浦光纤放大器(ROPA)的方法,该方法使用级联拉曼放大来增加可传递给ROPA的最大泵浦功率量。 根据现有技术,ROPA泵浦波长λp处的高功率直接发射到光纤中,并且最大发射功率受到拉曼噪声泵浦耗尽的开始和由于〜( ?p + 100)nm。 在本发明的优选实施例中,波长小于λp的“初级”泵浦源与两个或多个明显较低功率的“种子”源一起发射到输送光纤中,其中包括一个在pp。 种子源的波长和功率被选择为使得当与高功率初级源组合时,光纤内的拉曼转换的n系列n(n)最终导致高功率的发展 在? 在另一实施例中,波长小于λp的一个或多个种子源被反射装置所取代,以将光纤中的大功率产生的向后行进放大的自发拉曼散射光以波长一拉曼平移 低于特定的种子波长。 在任一种情况下,在pp上的高功率在光纤的分布长度上显影,达到其最大距离到光纤并且超过现有技术在该点可能的最大功率。