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1. 发明授权

US11884603B2 Process for producing humic acid salts with fluidizing solid phase reaction 有权
公开(公告)号：US11884603B2
公开(公告)日：2024-01-30
申请号：US17559303
申请日：2021-12-22
申请人： James Chin Cheng Yang
发明人： James Chin Cheng Yang
IPC分类号： C05F11/06 , C07D521/00 , B01J8/18 , C05F11/02 , B01J19/18 , B01J2/18 , B01J8/42 , B01F35/60
CPC分类号： C05F11/06 , B01F35/605 , B01J2/18 , B01J8/1836 , B01J8/42 , B01J19/1806 , C05F11/02 , C07D521/00 , C05F11/02 , C05F11/06
摘要： The present invention utilizes a high-speed intensive mixer in a fluidizing-type, solid-phase, neutralization reactor to blend solid-state alkali hydroxide with any humic acid sources. The final product is a dry humic acid salt. The purpose of this innovative method is to eliminate a series of complicated unit operations commonly employed by the traditional process. These removed steps may include dissolving caustic soda, mixing in a paste-like formation, extrusion, granulation, drying, and grinding, etc. The invention contributes to a simplified flowsheet, resulting in sharply reduced equipment investment, plant space, and labor and energy costs. All of these factors coupled with increased productivity will drastically lower the overall production cost. Also, the reduction of dust pollution will greatly minimize the impact in environmental protection and safety issues.

2. 发明授权

US11794158B2 Microparticle production process and apparatus 有权
公开(公告)号：US11794158B2
公开(公告)日：2023-10-24
申请号：US17204676
申请日：2021-03-17
申请人： MIDATECH PHARMA (WALES) LIMITED
发明人： Paul Seaman , Huw Jones , Liam McAleer
IPC分类号： B01J2/08 , B01J2/04 , B01J2/18 , B01J2/06
CPC分类号： B01J2/08 , B01J2/04 , B01J2/06 , B01J2/18
摘要： Provided is an apparatus for producing solid polymeric microparticles, the apparatus comprising a plurality of liquid droplet generators for forming liquid droplets of a first liquid, and a nozzle for forming a jet of a second liquid, wherein the plurality of liquid droplet generators and the nozzle are arranged relative to each other such that, in use, liquid droplets from the plurality of liquid droplet generators pass through a gas into said jet of second liquid. Also provided is a process for producing solid microparticles, the process comprising: providing a first liquid comprising a solute and a solvent, the solute comprising a biocompatible polymer, the concentration of polymer in the first liquid being at least 10% w/v, ‘w’ being the weight of the polymer and ‘v’ being the volume of the solvent, providing a plurality of liquid droplet generators operable to generate liquid droplets, providing a jet of a second liquid, causing the plurality of liquid droplet generators to form liquid droplets of the first liquid, passing the liquid droplets through a gas to contact the jet of the second liquid so as to cause the solvent to exit the droplets, thus forming solid microparticles, the solubility of the solvent in the second liquid being at least 5 g of solvent per 100 ml of second liquid, the solvent being substantially miscible with the second liquid.

3. 发明授权

US11794155B2 Mechanical system that fluidizes, mixes, coats, dries, combines, chemically reacts, and segregates materials 有权
公开(公告)号：US11794155B2
公开(公告)日：2023-10-24
申请号：US17464370
申请日：2021-09-01
申请人： Resodyn Corporation
发明人： Peter A. Lucon , Lawrence C. Farrar
IPC分类号： B01F31/24 , B01J2/18 , B01F31/25 , B01J2/00 , B01J2/04 , B01F33/30 , B01F35/90 , B01F35/213 , B01F35/21 , B01F35/221 , B01F35/71 , B01F31/20
CPC分类号： B01F31/25 , B01F31/24 , B01F33/30 , B01F35/213 , B01F35/2115 , B01F35/2213 , B01F35/7179 , B01F35/90 , B01J2/006 , B01J2/04 , B01J2/18 , B01F31/265 , B01F2035/98
摘要： The present application is directed towards systems and methods for adding components to materials being fluidized in a vibratory mixer by use of atomizers or sprayers. A mechanical system can fluidizes, mix, coat, dry, combine, or segregate materials. The system may comprise a vibratory mixer, mixing vessel containing a first material and a sprayer to introduce a second material. The vibratory mixer may generate a fluidized bed of a first material and the sprayer, coupled to the mixing vessel, may introduce a second material onto the fluidized bed to mix the materials in a uniform and even fashion.

4. 发明公开

US20230294067A1 Reactor System for Producing and/or Treating Particles in an Oscillating Process Gas Flow 审中-公开
公开(公告)号：US20230294067A1
公开(公告)日：2023-09-21
申请号：US17915639
申请日：2021-03-25
申请人： Glatt Ingenieurtechnik Gesellschaft mit beschränkter Haftung
发明人： Frank Ohlendorf , Arne Teiwes , Louis Friedrich , Michael Jacob
IPC分类号： B01J19/24 , B01J19/00 , B01J8/08 , B01J8/16 , F23C15/00 , F23N1/04 , B01J2/18
CPC分类号： B01J19/241 , B01J19/0013 , B01J8/085 , B01J8/087 , B01J8/16 , F23C15/00 , F23N1/042 , B01J2/18 , B01J2208/00504 , B01J2219/00157 , B01J2208/00566
摘要： A reactor system for the production and/or treatment of particles in an oscillating process gas stream. The reactor system includes a reactor unit that has an upstream feed unit and a downstream discharge unit and a reactor that includes a multiple burner system that has a combustion chamber, an exhaust gas pipe that follows downstream from the combustion chamber, and a plurality of burners. A part of the burners of the multiple burner systems are suitable for production of the oscillating process gas stream. The burners of the multiple burner system are arranged in the combustion chamber of the reactor unit.

5. 发明申请

US20230077586A1 Microparticle Production Platform, Method of Producing Microparticles and a Pharmaceutical Composition 有权
公开(公告)号：US20230077586A1
公开(公告)日：2023-03-16
申请号：US17801496
申请日：2021-02-25
申请人： Midatech Pharma (Wales) Limited
发明人： Paul Seaman , Connor Davies , Louis King
IPC分类号： B01J2/04 , B01J2/18 , A61K9/16 , A61K38/13 , A61K38/12
摘要： The present invention comprises an apparatus and method for producing a microparticle and pharmaceutical compositions thereof. The apparatus and method rely on continuous inkjet (CIJ) printing to provide high quality microparticles at an improved rate.

6. 发明授权

US11511248B2 Method for controlling a vibrating prilling bucket in a urea prilling process 有权
公开(公告)号：US11511248B2
公开(公告)日：2022-11-29
申请号：US17763400
申请日：2020-09-01
申请人： Casale SA
发明人： Leonardo Marrone
IPC分类号： B01J2/18 , B01J2/02
摘要： A method for controlling a prilling bucket in the prilling of a a urea melt (UM) including: feeding the urea melt to a prilling bucket (1) which vibrates under the action of a magnetostrictive device (2), wherein the vibration of the bucket is controlled, as a function of the amount of urea melt to be prilled, by the following steps: acquisition of a time-varying input signal (3) which represents the flow rate of urea melt fed to the prilling bucket; generation of a first signal (5) and of a second signal (6), independently from each other, as a function of said input signal (3); generation of a third signal (10) having a frequency which is modulated by said first signal and an magnitude which is modulated by said second signal, and use of said third signal to drive said magnetostrictive device (2).

7. 发明授权

US11499777B2 Liquid feeding device for the generation of droplets 有权
公开(公告)号：US11499777B2
公开(公告)日：2022-11-15
申请号：US16736832
申请日：2020-01-08
申请人： Sanofi Pasteur SA
发明人： Thomas Gebhard , Roland Kaiser , Bernhard Luy , Matthias Plitzko , Manfred Struschka , Christian Zerillo
IPC分类号： F26B5/06 , B01J2/04 , B01J2/18 , B01D1/18 , A61K9/19 , A61K39/00
摘要： The present invention provides, inter alia, for a liquid feeding device for the generation of droplets, in particular for the use in a process line for the production of freeze-dried particles, with a droplet ejection section for ejecting liquid droplets in an ejection direction, the droplet ejection section comprising at least one inlet port for receiving a liquid to be ejected, a liquid chamber for retaining the liquid, and a nozzle for ejecting the liquid from the liquid chamber to form droplets, wherein the liquid chamber is restricted by a membrane on one side thereof, the membrane being vibratable by an excitation unit, wherein the longitudinal axis of the liquid chamber is tilted relative to the longitudinal axis of the nozzle, and/or the liquid feeding device further comprises a deflection section for separating the droplets from each other by means of at least one gas jet, wherein the deflection section gas jet intersects perpendicular with an ejection path of the liquid ejected from the liquid chamber.

8. 发明申请

US20220112137A1 New Process for Producing Humic Acid Salts with Fluidizing Solid Phase Reaction 有权
公开(公告)号：US20220112137A1
公开(公告)日：2022-04-14
申请号：US17559303
申请日：2021-12-22
申请人： James Chin Cheng YANG
发明人： James Chin Cheng YANG
IPC分类号： C05F11/06 , C07D521/00 , B01J8/18 , C05F11/02 , B01J19/18 , B01J2/18 , B01J8/42 , B01F35/60
摘要： The present invention utilizes a high-speed intensive mixer in a fluidizing-type, solid-phase, neutralization reactor to blend solid-state alkali hydroxide with any humic acid sources. The final product is a dry humic acid salt. The purpose of this innovative method is to eliminate a series of complicated unit operations commonly employed by the traditional process. These removed steps may include dissolving caustic soda, mixing in a paste-like formation, extrusion, granulation, drying, and grinding, etc. The invention contributes to a simplified flowsheet, resulting in sharply reduced equipment investment, plant space, and labor and energy costs. All of these factors coupled with increased productivity will drastically lower the overall production cost. Also, the reduction of dust pollution will greatly minimize the impact in environmental protection and safety issues.

9. 发明申请

US20220062178A1 PARTICULATE POLY(LACTIC-CO-GLYCOLIC) ACID, METHOD FOR MANUFACTURING PARTICULATE POLY(LACTIC-CO-GLYCOLIC) ACID, AND PARTICULATE POLY(LACTIC-CO-GLYCOLIC) ACID MANUFACTURING APPARATUS 有权
公开(公告)号：US20220062178A1
公开(公告)日：2022-03-03
申请号：US17525521
申请日：2021-11-12
申请人： RICOH COMPANY, LTD.
发明人： Tadahiko Morinaga , Tatsuru Moritani , Tatsuki Yamaguchi , Masaru Ohgaki , Shinji Aoki , Yuichi Sato
IPC分类号： A61K9/16 , C08G63/06 , B01J2/04 , B01J2/18
摘要： A particulate poly(lactic-co-glycolic) acid (PLGA) is provided. The particulate PLGA comprises a poly(lactic-co-glycolic) acid (PLGA), and has an average volume-based particle diameter of 80 nm or less and a relative span factor (R.S.F.) satisfying the following formula (1): 0

10. 发明申请

US20210086156A1 AGGREGATE PROCESSING SYSTEMS, METHODS AND APPARATUS 有权
公开(公告)号：US20210086156A1
公开(公告)日：2021-03-25
申请号：US17026762
申请日：2020-09-21
申请人： Superior Industries, Inc.
发明人： Matt Esson , Luke Hogan
IPC分类号： B01J2/18 , B01J19/00 , C10G33/06
摘要： Aggregate material processing systems, methods, and apparatus are described. In some embodiments, one or more components have a transport configuration and an operational configuration.

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