专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US09867536B2 Methods for comprehensive Fourier domain optical coherence tomography (FDOCT) 有权
公开(公告)号：US09867536B2
公开(公告)日：2018-01-16
申请号：US15042592
申请日：2016-02-12
申请人： Bioptigen, Inc.
发明人： Joseph A. Izatt , Eric L. Buckland , Bradley A. Bower , Robert H. Hart
IPC分类号： A61B3/10 , G01B9/02 , A61B3/117 , A61B3/12
CPC分类号： A61B3/102 , A61B3/117 , A61B3/1225 , G01B9/0201 , G01B9/02078 , G01B9/02091
摘要： Optical coherence tomography systems for imaging a whole eye are provided including a sample arm including focal optics that are configured to rapidly switch between at least two scanning modes in less than about 1.0 second.

2. 发明申请

US20170241764A1 Method and System for Regional Phase Unwrapping with Pattern-Assisted Correction 有权
公开(公告)号：US20170241764A1
公开(公告)日：2017-08-24
申请号：US14980215
申请日：2015-12-28
申请人： KLA-Tencor Corporation
发明人： Helen Liu , Xuan Zhao , Xiaowei Li
IPC分类号： G01B9/02 , G01B11/06
CPC分类号： G01B9/02083 , G01B9/02078 , G01B9/02088 , G01B11/0608 , G01B11/2441 , G01B2210/56
摘要： A wafer metrology system includes an interferometer sub-system and a controller. The interferometer sub-system is configured to generate an interferogram with an intensity map that corresponds to a modulated representation of a wafer surface. Further, the interferometer sub-system includes a detector configured to capture the interferogram. The controller includes one or more processors configured to generate a wrapped phase map of the interferogram, define patterns associated with features on the wafer, and correct phase discontinuities by applying a phase unwrapping procedure to the wrapped phase map to generate an unwrapped phase map and correcting phase discontinuities in the unwrapped phase map based on the patterns, or by combining phase unwrapping and correction in a unified step. Further, the patterns comprise two or more structures such that a portion of the unwrapped phase map associated with structures of the same type is continuous across borders separating structures of the same type.

3. 发明授权

US09279659B2 Systems and methods for complex conjugate artifact resolved optical coherence tomography 有权
标题翻译：复杂结合伪影解析光学相干断层扫描的系统和方法
公开(公告)号：US09279659B2
公开(公告)日：2016-03-08
申请号：US13355381
申请日：2012-01-20
申请人： Joseph A. Izatt , Al-Hafeez Dhalla
发明人： Joseph A. Izatt , Al-Hafeez Dhalla
IPC分类号： G01B9/02 , A61B3/10
CPC分类号： G01B9/02091 , A61B3/102 , G01B9/02004 , G01B9/0201 , G01B9/02078
摘要： Systems and methods are disclosed for optical coherence tomography (OCT). For example, imaging can use optical phase modulators based on optical delay lines that, in conjunction with a swept-source laser, can be used to achieve heterodyne swept source optical coherence tomography (SSOCT). These techniques resolve the complex conjugate ambiguity in SSOCT, thereby doubling the usable imaging range. This increased imaging range has numerous important clinical applications in ophthalmology, cardiology and radiology, as well as applications in small animal and non-biological imaging. These methods are superior to prior disclosed methods requiring acousto-optic or electro-optic modulators with respect to complexity, efficiency, imaging speed and image quality.
摘要翻译：公开了用于光学相干断层摄影（OCT）的系统和方法。例如，成像可以使用基于光学延迟线的光学相位调制器，其结合扫频激光器可用于实现外差扫描光学相干断层扫描（SSOCT）。这些技术解决了SSOCT中复杂的共轭歧义，从而使可用成像范围翻倍。这种增加的成像范围在眼科，心脏病学和放射学以及小动物和非生物成像中的应用具有许多重要的临床应用。这些方法优于先前公开的在复杂性，效率，成像速度和图像质量方面需要声光或电光调制器的方法。

4. 发明申请

US20140160431A1 Systems for Comprehensive Fourier Domain Optical Coherence Tomography (FDOCT) and Related Methods 有权
标题翻译：综合傅里叶域光学相干断层扫描系统（FDOCT）及相关方法
公开(公告)号：US20140160431A1
公开(公告)日：2014-06-12
申请号：US14148100
申请日：2014-01-06
申请人： Bioptigen, Inc.
发明人： Joseph A. Izatt , Eric L. Buckland , Bradley A. Bower , Robert H. Hart
IPC分类号： A61B3/10
CPC分类号： A61B3/102 , A61B3/117 , A61B3/1225 , G01B9/0201 , G01B9/02078 , G01B9/02091
摘要： Optical coherence tomography systems for imaging a whole eye are provided including a sample arm including focal optics that are configured to rapidly switch between at least two scanning modes in less than about 1.0 second.
摘要翻译：提供了用于对整个眼睛进行成像的光学相干断层摄影系统，包括包括焦点光学元件的样本臂，其配置为在小于约1.0秒内在至少两个扫描模式之间快速切换。

5. 发明申请

US20130265585A1 SYSTEMS AND METHODS FOR PHASE MEASUREMENTS 有权
标题翻译：用于相位测量的系统和方法
公开(公告)号：US20130265585A1
公开(公告)日：2013-10-10
申请号：US13715475
申请日：2012-12-14
申请人： David Feld , Jonathan Feld , Alison Hearn
发明人： Christopher Fang-Yen , Gabriel Popescu , Changhuei Yang , Adam Wax , Ramachandra Dasari , Michael Feld
IPC分类号： G01B9/02
CPC分类号： G01B9/02091 , A61B5/14532 , A61B5/1455 , A61B5/7232 , G01B9/02002 , G01B9/02007 , G01B9/02011 , G01B9/02057 , G01B9/02063 , G01B9/02067 , G01B9/02069 , G01B9/02071 , G01B9/02072 , G01B9/02078 , G01B9/02083 , G01B9/0209 , G01B2290/45 , G01B2290/60 , G01B2290/70 , G01J9/04 , G01N21/45
摘要： Preferred embodiments of the present invention are directed to systems for phase measurement such as for imaging small biological objects with light. These embodiments can be applied to the fields of, for example, cellular physiology and neuroscience. These preferred embodiments are based on principles of phase measurements and imaging technologies. The scientific motivation for using phase measurements and imaging technologies is derived from, for example, cellular biology at the sub-micron level which can include, without limitation, imaging origins of dysplasia, cellular communication, neuronal transmission and implementation of the genetic code. Light based techniques with nanometer resolution enable the cellular machinery to be studied in its native state. Thus, preferred embodiments of the present invention include systems based on principles of interferometry and/or phase measurements and are used to study cellular physiology. These systems include principles of low coherence interferometry (LCI) using optical interferometers to measure phase, or light scattering spectroscopy (LSS) wherein interference within the cellular components themselves is used, or in the alternative the principles of LCI and LSS can be combined to result in systems of the present invention.
摘要翻译：本发明的优选实施例涉及用于相位测量的系统，例如用于利用光成像小生物物体。这些实施方案可以应用于例如细胞生理学和神经科学领域。这些优选实施例基于相位测量和成像技术的原理。使用相位测量和成像技术的科学动机源于例如亚微米级别的细胞生物学，其可以包括但不限于成像发育异常起源，细胞通讯，神经元传播和遗传密码的实现。具有纳米分辨率的基于光的技术使得能够以其天然状态研究细胞机械。因此，本发明的优选实施例包括基于干涉测量和/或相位测量的原理的系统，并且用于研究细胞生理学。这些系统包括使用光学干涉仪来测量相位的低相干干涉测量（LCI）原理，或使用其中使用细胞部件本身内部的干扰的光散射光谱（LSS），或者替代地，LCI和LSS的原理可以组合以产生在本发明的系统中。

6. 发明申请

US20100226554A1 OPTICAL COHERENCE TOMOGRAPHY METHOD AND OPTICAL COHERENCE TOMOGRAPHY APPARATUS 有权
标题翻译：光学相干方法和光学相干计算机
公开(公告)号：US20100226554A1
公开(公告)日：2010-09-09
申请号：US12709731
申请日：2010-02-22
申请人： Nobuhito Suehira
发明人： Nobuhito Suehira
IPC分类号： G06K9/62 , G01J3/45
CPC分类号： G01B9/02044 , A61B3/102 , G01B9/02063 , G01B9/02078 , G01B9/02085 , G01B9/02091
摘要： An optical coherence tomography method according to the present invention comprising the steps of dividing an object to be measured into a plurality of measurement regions adjacent to one another in a direction of irradiation of a measurement light, and acquiring a measurement image for every measurement region based on a wavelength spectrum of a coherent light and acquiring a tomographic image for every measurement region by removing a mirror image of a tomographic image of an adjacent region being adjacent to the measurement region of the measurement image from the measurement image.
摘要翻译：根据本发明的光学相干断层摄影方法包括以下步骤：将被测量物体沿测量光的照射方向彼此相邻的多个测量区域分割，并且基于每个测量区域获取测量图像在相干光的波长光谱上，通过从测量图像中去除与测量图像的测量区域相邻的相邻区域的断层图像的镜像来获取每个测量区域的断层图像。

7. 发明授权

US07791731B2 Partial coherence interferometer with measurement ambiguity resolution 有权
标题翻译：具有测量模糊度分辨率的部分相干干涉仪
公开(公告)号：US07791731B2
公开(公告)日：2010-09-07
申请号：US11958411
申请日：2007-12-18
申请人： David B. Kay
发明人： David B. Kay
IPC分类号： G01B9/02
CPC分类号： G01B9/02027 , G01B9/02007 , G01B9/02044 , G01B9/02074 , G01B9/02078 , G01B9/0209 , G01B2290/45
摘要： A partial coherence interferometer incorporates a focusing system for resolving measurement ambiguities. A focus-sensing beam is directed through a common objective with the measurement beam of the interferometer for conveying the beams to and from a test surface. An unambiguous measuring range is equated to a predetermined range of focusing errors.
摘要翻译：部分相干干涉仪结合了用于分辨测量模糊度的聚焦系统。聚焦感测光束通过与干涉仪的测量光束通过共同的目标，用于将光束传送到测试表面和从测试表面传送光束。无歧义的测量范围等于预定范围的聚焦误差。

8. 发明申请

US20090244547A1 OPTICAL TOMOGRAPHIC IMAGING SYSTEM, TOMOGRAPHIC IMAGE ACQUIRING METHOD, AND OPTICAL TOMOGRAPHIC IMAGE FORMING METHOD 有权
标题翻译：光学图像成像系统，图像摄影方法和光学图像成像方法
公开(公告)号：US20090244547A1
公开(公告)日：2009-10-01
申请号：US12414371
申请日：2009-03-30
申请人： Satoshi OZAWA
发明人： Satoshi OZAWA
IPC分类号： G01B11/24
CPC分类号： G01B9/02064 , A61B5/0066 , A61B5/7257 , G01B9/02004 , G01B9/02078 , G01B9/02085 , G01B9/02091 , G01B2290/35 , G01J1/0407 , G01J1/0422 , G01N21/4795
摘要： This optical tomographic imaging system comprises an optical path length adjustor configured to set a first reference position of a measurement depth direction to an inner edge of a measurement range by adjusting an optical path length of a reference light, and an optical path length switching unit having a preset optical path length that provides a second reference position differing in measurement depth from the first reference position by a predetermined amount and configured to change the optical path length of the reference light or the optical path length of the reflected light adjusted by the optical path length adjustor so as to switch between the first reference position and the second reference position. This system is capable of measuring a measurement region of interest at high resolution, regardless of the position (depth) of the measurement region of interest, in an SS-OCT employing a wavelength-swept light source.
摘要翻译：该光学断层成像系统包括光路长度调节器，其被配置为通过调整参考光的光路长度来将测量深度方向的第一参考位置设置到测量范围的内边缘，以及光路长度切换单元，其具有预设的光程长度，其将测量深度与第一参考位置不同的第二参考位置提供预定量，并且被配置为改变参考光的光路长度或由光路调节的反射光的光路长度长度调节器，以便在第一参考位置和第二参考位置之间切换。在采用波长扫描光源的SS-OCT中，无论感兴趣的测量区域的位置（深度）如何，该系统能够以高分辨率测量感兴趣的测量区域。

9. 发明授权

US07557929B2 Systems and methods for phase measurements 有权
标题翻译：相位测量的系统和方法
公开(公告)号：US07557929B2
公开(公告)日：2009-07-07
申请号：US10871610
申请日：2004-06-18
申请人： Christopher M. Fang-Yen , Gabriel Popescu , Changhuei Yang , Adam Wax , Ramachandra R. Dasari , Michael S. Feld
发明人： Christopher M. Fang-Yen , Gabriel Popescu , Changhuei Yang , Adam Wax , Ramachandra R. Dasari , Michael S. Feld
IPC分类号： G01B9/02 , G01B11/02
CPC分类号： G01B9/02091 , A61B5/14532 , A61B5/1455 , A61B5/7232 , G01B9/02002 , G01B9/02007 , G01B9/02011 , G01B9/02057 , G01B9/02063 , G01B9/02067 , G01B9/02069 , G01B9/02071 , G01B9/02072 , G01B9/02078 , G01B9/02083 , G01B9/0209 , G01B2290/45 , G01B2290/60 , G01B2290/70 , G01J9/04 , G01N21/45
摘要： Preferred embodiments of the present invention are directed to systems for phase measurement which address the problem of phase noise using combinations of a number of strategies including, but not limited to, common-path interferometry, phase referencing, active stabilization and differential measurement. Embodiment are directed to optical devices for imaging small biological objects with light. These embodiments can be applied to the fields of, for example, cellular physiology and neuroscience. These preferred embodiments are based on principles of phase measurements and imaging technologies. The scientific motivation for using phase measurements and imaging technologies is derived from, for example, cellular biology at the sub-micron level which can include, without limitation, imaging origins of dysplasia, cellular communication, neuronal transmission and implementation of the genetic code. The structure and dynamics of sub-cellular constituents cannot be currently studied in their native state using the existing methods and technologies including, for example, x-ray and neutron scattering. In contrast, light based techniques with nanometer resolution enable the cellular machinery to be studied in its native state. Thus, preferred embodiments of the present invention include systems based on principles of interferometry and/or phase measurements and are used to study cellular physiology. These systems include principles of low coherence interferometry (LCI) using optical interferometers to measure phase, or light scattering spectroscopy (LSS) wherein interference within the cellular components themselves is used, or in the alternative the principles of LCI and LSS can be combined to result in systems of the present invention.
摘要翻译：本发明的优选实施例涉及用于相位测量的系统，其使用多种策略的组合来解决相位噪声问题，包括但不限于公共路径干涉测量，相位参考，主动稳定和差分测量。实施例涉及用于用光成像小生物物体的光学装置。这些实施方案可以应用于例如细胞生理学和神经科学领域。这些优选实施例基于相位测量和成像技术的原理。使用相位测量和成像技术的科学动机源于例如亚微米级别的细胞生物学，其可以包括但不限于成像发育异常起源，细胞通讯，神经元传播和遗传密码的实现。亚细胞组分的结构和动力学目前不能使用现有的方法和技术（例如x射线和中子散射）在其天然状态下研究。相比之下，具有纳米分辨率的基于光的技术使得能够以其天然状态研究细胞机械。因此，本发明的优选实施例包括基于干涉测量和/或相位测量的原理的系统，并且用于研究细胞生理学。这些系统包括使用光学干涉仪来测量相位的低相干干涉测量（LCI）原理，或使用其中使用细胞部件本身内部的干扰的光散射光谱（LSS），或者替代地，LCI和LSS的原理可以组合以产生在本发明的系统中。

10. 发明授权

US07426036B2 Common path frequency domain optical coherence reflectometer and common path frequency domain optical coherence tomography device 失效
标题翻译：共路径频域光学相干反射计和共同路径频域光学相干断层扫描装置
公开(公告)号：US07426036B2
公开(公告)日：2008-09-16
申请号：US11456414
申请日：2006-07-10
申请人： Felix I. Feldchtein , Grigory V. Gelikonov
发明人： Felix I. Feldchtein , Grigory V. Gelikonov
IPC分类号： G01B9/02 , G01B11/02
CPC分类号： G01B9/02065 , A61B5/0066 , A61B5/6852 , G01B9/02044 , G01B9/02057 , G01B9/02078 , G01B9/02091 , G01B2290/70 , G01N21/4795
摘要： Common path frequency domain optical coherence reflectometry/tomography devices with an additional interferometer are suggested. The additional interferometer offset is adjusted such, that it is ether less than the reference offset, or exceeds the distance from the reference reflector to the distal boundary of the longitudinal range of interest. This adjustment allows for relieving the requirements to the spectral resolution of the frequency domain optical coherence reflectometry/tomography engine and/or speed of the data acquisition and processing system, and eliminates depth ambiguity problems. The new topology allows for including a phase or frequency modulator in an arm of the additional interferometer improving the signal-to-noise ratio of the devices. The modulator is also capable of substantially eliminating mirror ambiguity, DC artifacts, and autocorrelation artifacts. The interference signal is produced either in the interferometer or inside of the optical fiber probe leading to the sample.
摘要翻译：建议使用带有附加干涉仪的共路径频域光学相干反射/断层成像装置。调整附加的干涉仪偏移，使得其比参考偏移小，或者超过距参考反射器到感兴趣的纵向范围的远端边界的距离。该调整允许缓解对频域光学相干反射/断层摄影引擎的光谱分辨率和/或数据采集和处理系统的速度的要求，并消除深度歧义问题。新的拓扑结构允许在附加干涉仪的臂中包括相位或频率调制器来提高器件的信噪比。调制器还能够基本上消除镜像歧义，DC伪影和自相关伪影。在干涉仪中产生干涉信号，或者在通过样品的光纤探针的内部产生干扰信号。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式