专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US11385447B2 Microscopes including illumination field diaphragms 有权
公开(公告)号：US11385447B2
公开(公告)日：2022-07-12
申请号：US16511046
申请日：2019-07-15
申请人： Bioptigen, Inc.
发明人： Christopher Saxer , Al-Hafeez Z. Dhalla , Robert H. Hart , Eric L. Buckland
IPC分类号： G02B21/00 , A61B3/10 , A61B3/12 , G02B21/08 , G02B27/00 , G02B5/00 , G02B7/00 , G02B21/02 , G02B21/06 , G02B21/22
摘要： Surgical microscopes are provided including at least one ocular, an objective lens; a collimated space between the at least one ocular and the objective lens; an illumination system optically coupled into the collimated space of the surgical microscope, wherein an illumination from the illumination system is directed along a path at least partially contained within the collimated space of the surgical microscope and through the objective lens; and one of a field diaphragm and obscuration mask positioned within the illumination system, and outside of a field of view of the at least one ocular, wherein the one of the field diaphragm and the obscuration mask blocks, attenuates or diverts rays from the illumination system that reflect from a surface of the objective lens such that the reflected rays are not visible through the at least one ocular.

2. 发明申请

US20200054206A1 PROCEDURAL OPTICAL COHERENCE TOMOGRAPHY (OCT) FOR SURGERY AND RELATED METHODS 审中-公开
公开(公告)号：US20200054206A1
公开(公告)日：2020-02-20
申请号：US16665106
申请日：2019-10-28
申请人： Bioptigen, Inc.
发明人： Eric L. Buckland , Al-Hafeez Dhalla , Robert H. Hart
IPC分类号： A61B3/10 , A61F2/16 , A61B3/103 , A61B3/00 , A61B3/107
摘要： Methods are provided for performing a surgical procedure using optical coherence tomography (OCT) including extracting lenticular material from within a capsular bag of the eye of a patient; placing a replacement lens within the capsular bag after extraction of the lenticular material from the capsular bag; acquiring a plurality of OCT images that visualize the placement of the replacement lens within the capsular bag; and determining from the plurality of OCT images a degree of contact of the posterior surface of the replacement lens with the posterior portion of the capsular bag.

3. 发明申请

US20190339499A1 Microscopes Including Illumination Field Diaphragms 审中-公开
公开(公告)号：US20190339499A1
公开(公告)日：2019-11-07
申请号：US16511046
申请日：2019-07-15
申请人： Bioptigen, Inc.
发明人： Christopher Saxer , AI-Hafeez Z. Dhalla , Robert H. Hart , Eric L. Buckland
IPC分类号： G02B21/00 , G02B27/00 , G02B21/08 , A61B3/12 , A61B3/10 , G02B7/00 , G02B21/22 , G02B5/00 , G02B21/06 , G02B21/02
摘要： Surgical microscopes are provided including at least one ocular, an objective lens; a collimated space between the at least one ocular and the objective lens; an illumination system optically coupled into the collimated space of the surgical microscope, wherein an illumination from the illumination system is directed along a path at least partially contained within the collimated space of the surgical microscope and through the objective lens; and one of a field diaphragm and obscuration mask positioned within the illumination system, and outside of a field of view of the at least one ocular, wherein the one of the field diaphragm and the obscuration mask blocks, attenuates or diverts rays from the illumination system that reflect from a surface of the objective lens such that the reflected rays are not visible through the at least one ocular.

4. 发明授权

US10362936B2 Methods of performing surgery using optical coherence tomography (OCT) 有权
公开(公告)号：US10362936B2
公开(公告)日：2019-07-30
申请号：US15783007
申请日：2017-10-13
申请人： Bioptigen, Inc.
发明人： Eric L. Buckland , Al-Hafeez Dhalla , Robert H. Hart
IPC分类号： A61B3/00 , A61B3/10 , A61B3/107 , A61B3/103 , A61F2/16 , A61F9/008 , A61B90/00 , A61B34/10
摘要： Methods are provided including obtaining at least one image of a surgical region of a subject oriented for the surgical procedure using an OCT imaging system. An initial structural view of the surgical region to be used during the surgical procedure is constructed based on the obtained at least one OCT image. Parameters are computed as an end point for assessing an outcome of the surgical procedure using data derived from the OCT image. The surgical procedure is periodically assessed and clinical outcomes are monitored using changes to the OCT-derived initial structural view of the surgical region or changes to the computed at least one clinical parameter. It is determined if the surgical plan needs modification and it is modified during the surgical procedure. Operations repeat until it is determined that no more modifications are needed.

5. 发明授权

US10271725B2 Hybrid telescope for optical beam delivery and related systems 有权
公开(公告)号：US10271725B2
公开(公告)日：2019-04-30
申请号：US15826966
申请日：2017-11-30
申请人： Bioptigen, Inc.
发明人： Eric L. Buckland , Andrew Murnan , Nestor O. Farmiga , Robert H. Hart , Christopher Saxer
IPC分类号： A61B3/10 , G01B9/02 , G02B19/00 , G02B23/24
摘要： Optical coherence tomography (OCT) imaging systems are provided including a source of broadband optical radiation coupled to a sample arm of the OCT imaging system; a beam shaping optical assembly in the sample arm, the beam shaping optical assembly being configured to receive optical radiation from the source as a beam of optical radiation and to shape the spatial profile of the beam of optical radiation; a scan mirror assembly coupled to the beam shaping optical assembly; and objective lens assembly coupled to the beam shaping optical assembly. The beam shaping optical assembly includes a lens assembly configured to change a NA of the OCT system without changing a focus; to change a focus of the OCT system without changing a NA of the system; or to change both the NA and the focus of the OCT system responsive to a control input.

6. 发明授权

US09560963B2 Procedural optical coherence tomography (OCT) for surgery and related methods 有权
标题翻译：手术光学相干断层扫描（OCT）及相关方法
公开(公告)号：US09560963B2
公开(公告)日：2017-02-07
申请号：US14834798
申请日：2015-08-25
申请人： Bioptigen, Inc.
发明人： Eric L. Buckland , Al-Hafeez Dhalla , Robert H. Hart
IPC分类号： A61B3/10 , A61B3/107 , A61B3/00 , A61B3/103 , A61F2/16 , A61F9/008
CPC分类号： A61B3/102 , A61B3/0025 , A61B3/0041 , A61B3/1005 , A61B3/103 , A61B3/107 , A61B2034/108 , A61B2090/3735 , A61F2/16 , A61F2009/00851 , G06F19/00
摘要： Methods for performing a surgical procedure using optical coherence tomography (OCT) are provided. The method includes extracting lenticular material from within a capsular bag of an eye of a patient; acquiring at least one OCT image of an interior region of the capsular bag after extraction of substantially all of the lenticular material from within the capsular bag; determining from the at least one OCT image the presence of cellular debris remaining within the interior of the capsular bag; and extracting at least a portion of the remaining cellular debris from the interior of the capsular bag.
摘要翻译：提供了使用光学相干断层扫描（OCT）进行外科手术的方法。该方法包括从患者眼睛的囊袋内提取透镜材料; 从胶囊袋中提取基本上所有的透镜材料之后，获取囊袋内部区域的至少一个OCT图像; 从所述至少一个OCT图像确定残留在所述囊袋内部的细胞碎片的存在; 以及从囊袋的内部提取剩余细胞碎片的至少一部分。

7. 发明授权

US09513453B2 Ball cage assemblies for centration of axially thick lenses and related methods and systems 有权
标题翻译：用于轴向厚透镜中心的球笼组件及相关方法和系统
公开(公告)号：US09513453B2
公开(公告)日：2016-12-06
申请号：US14573001
申请日：2014-12-17
申请人： Bioptigen, Inc.
发明人： Nestor O. Farmiga
IPC分类号： G02B7/02 , G02B27/62 , F21V17/02
CPC分类号： G02B7/02 , F21V17/02 , G02B7/023 , G02B27/62 , Y10T29/49876 , Y10T29/53913
摘要： A ball cage centered lens assembly is provided including an axially thick lens; an outer mechanical cell; an intermediate cage positioned between the axially thick lens and the outer mechanical cell; a plurality of deformable elements positioned within the cage, between the axially thick lens and the mechanical cell, and in contact with the axially thick lens and the outer mechanical cell.
摘要翻译：提供了一种球笼中心透镜组件，其包括轴向厚的透镜; 外部机械电池; 位于轴向厚透镜和外机械单元之间的中间笼; 多个可变形元件，定位在保持架内，在轴向厚的透镜和机械单元之间，并且与轴向厚的透镜和外部机械单元接触。

8. 发明授权

US09498121B2 Surgical microscopes using optical coherence tomography and related systems 有权
公开(公告)号：US09498121B2
公开(公告)日：2016-11-22
申请号：US14745980
申请日：2015-06-22
申请人： Bioptigen, Inc.
发明人： Eric L. Buckland , Nestor O. Farmiga , Robert H. Hart , Andrew Murnan , Christopher Saxer
IPC分类号： A61B3/14 , A61B3/00 , A61B3/10 , G01B9/02 , A61B3/13 , G02B21/00 , G02B21/02 , G02B27/00 , G02B27/09 , G02B27/14 , A61B5/00 , G02B1/11
CPC分类号： A61B3/102 , A61B3/13 , A61B3/132 , A61B5/0066 , G01B9/02039 , G01B9/02091 , G02B1/11 , G02B21/0012 , G02B21/0048 , G02B21/006 , G02B21/02 , G02B21/025 , G02B27/0031 , G02B27/0955 , G02B27/141
摘要： Some embodiments of the present inventive concept provide optical coherence tomography (OCT) systems for integration with a microscope. The OCT system includes a sample arm coupled to the imaging path of a microscope. The sample arm includes an input beam zoom assembly including at least two movable lenses configured to provide shape control for an OCT signal beam; a scan assembly including at least one scanning mirror and configured for telecentric scanning of the OCT signal beam; and a beam expander configured to set the OCT signal beam diameter incident on the microscope objective. The shape control includes separable controls for numerical aperture and focal position of the imaged OCT beam.

9. 发明授权

US09361518B2 Methods, systems and computer program products for diagnosing conditions using unique codes generated from a multidimensional image of a sample 有权
标题翻译：用于使用从样本的多维图像生成的唯一代码来诊断条件的方法，系统和计算机程序产品
公开(公告)号：US09361518B2
公开(公告)日：2016-06-07
申请号：US14336062
申请日：2014-07-21
申请人： Bioptigen, Inc.
发明人： Bradley A. Bower , Eric L. Buckland
IPC分类号： G06K9/00 , A61B5/00 , A61B5/117 , G06K7/14 , G06T11/00
CPC分类号： G06K9/00604 , A61B5/0062 , A61B5/0066 , A61B5/0068 , A61B5/117 , A61B5/1171 , A61B5/6821 , A61B5/6826 , G06K7/1413 , G06K7/1417 , G06K7/1447 , G06K9/00033 , G06K9/0008 , G06K9/00892 , G06T11/006
摘要： Methods of providing a diagnosis using a digital code associated with an image are provided including collecting a multidimensional image, the multidimensional image having at least two dimensions; extracting a two dimensional subset of the multidimensional image; reducing the multidimensional image to a first code that is unique to the multidimensional image based on the extracted two dimensional image; comparing the first unique code associated with the subject to a library of reference codes, each of the reference codes in the library of reference codes being indicative of a class of objects; determining if the subject associated with the first unique code falls into at least one of the classes of objects associated with the reference codes based on a result of the comparison; and formulating a diagnostic decision based on the whether the first unique code associated with the subject falls into at least one of the classes associated with the reference code. Related systems and computer program products are also provided herein.
摘要翻译：提供使用与图像相关联的数字代码提供诊断的方法，包括收集多维图像，所述多维图像具有至少两个维度; 提取多维图像的二维子集; 将所述多维图像减少为基于所提取的二维图像对于所述多维图像是唯一的第一代码; 将与主题相关联的第一唯一代码与参考代码库进行比较，参考代码库中的每个参考代码指示一类对象; 基于比较的结果，确定与第一唯一码相关联的被摄体是否落入与参考码相关联的对象类别中的至少一个中; 以及基于与所述对象相关联的所述第一唯一代码是否落入与所述参考代码相关联的类别中的至少一个中来制定诊断决策。本文还提供了相关系统和计算机程序产品。

10. 发明授权

US09271643B2 Compact multimodality optical coherence tomography imaging systems having a ring of optical fibers in image capture path 有权
标题翻译：具有图像捕捉路径中的光纤环的紧凑型多模光学相干断层成像系统
公开(公告)号：US09271643B2
公开(公告)日：2016-03-01
申请号：US14551916
申请日：2014-11-24
申请人： Bioptigen, Inc.
发明人： Bradley A. Bower , Robert H. Hart , Pete Huening , Eric L. Buckland
IPC分类号： G01B9/02 , A61B3/10 , A61B3/14
CPC分类号： A61B3/102 , A61B3/14 , G01B9/0203 , G01B9/02091
摘要： Systems for imaging a sample are provided. The system includes an optical coherence tomography (OCT) imaging portion having an associated OCT path defined by one set of optical elements between an OCT signal delivery optical fiber and the sample; an image capture portion having an associated image capture path defined by a second set of optical elements between an image capture device and the sample, different from the OCT path; and an illuminator portion having an associated illumination path defined by a third set of optical elements between an illumination source and the sample. The OCT path, the image capture path, and the illuminator path have at least one optical element in common, and the respective paths differ from each other by at least one optical element. The OCT path and the image capture path share a common intermediate conjugate image plane. Focal control is achieved for the OCT path and the image capture path concurrently through adjustment of one or more common optical elements distal to the common intermediate conjugate plane, such that focal control requires no differential adjustment between optical elements not in common to both paths.
摘要翻译：提供了用于成像样本的系统。该系统包括光学相干断层摄影（OCT）成像部分，其具有由OCT信号传送光纤和样本之间的一组光学元件限定的相关OCT路径; 图像捕获部分，具有由图像捕获装置和样本之间的不同于OCT路径的第二组光学元件定义的相关联的图像捕获路径; 以及具有由照明源和样品之间的第三组光学元件限定的相关联的照明路径的照明器部分。 OCT路径，图像捕获路径和照明器路径具有共同的至少一个光学元件，并且相应的路径由至少一个光学元件彼此不同。 OCT路径和图像捕获路径共享一个共同的中间共轭图像平面。通过调整远离公共中间共轭平面的一个或多个共同的光学元件，通过同时进行OCT路径和图像捕获路径的焦点控制，使得焦点控制不需要在两个路径不共同的光学元件之间进行差分调整。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式