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1. 发明授权

US09188537B2 Sensing method and sensing device 有权
标题翻译：感应方法和传感装置
公开(公告)号：US09188537B2
公开(公告)日：2015-11-17
申请号：US14007403
申请日：2012-03-05
申请人： Toshio Fukai , Atsushi Matsumoto , Kazuya Matsumoto , Takuro Suyama
发明人： Toshio Fukai , Atsushi Matsumoto , Kazuya Matsumoto , Takuro Suyama
IPC分类号： G01N21/64 , G01N33/66
CPC分类号： G01N21/643 , G01N21/6428 , G01N33/66 , Y10T436/144444
摘要： This invention relates to a sensing method and a sensing device for quantifying the concentration of an analyte by using the property that interaction between an analyte and a labeled compound changes fluorescence intensity. A fluorescence sensor is used to acquire fluorescence intensity at predetermined quantification time points. Then, the concentration of an analyte is quantified in accordance with a non-steady concentration quantification law including the relationship between the acquired fluorescence intensity and the time derivative quantity thereof.
摘要翻译：本发明涉及一种用于通过使用分析物和标记化合物之间的相互作用改变荧光强度的性质来定量分析物的浓度的感测方法和感测装置。荧光传感器用于在预定量化时间点获取荧光强度。然后，根据包括所获得的荧光强度与其时间衍生量之间的关系的非稳定浓度定量定律来定量分析物的浓度。

2. 发明申请

US20140017799A1 SENSING METHOD AND SENSING DEVICE 有权
标题翻译：感应方法和感应装置
公开(公告)号：US20140017799A1
公开(公告)日：2014-01-16
申请号：US14007403
申请日：2012-03-05
申请人： Toshio Fukai , Atsushi Matsumoto , Kazuya Matsumoto , Takuro Suyama
发明人： Toshio Fukai , Atsushi Matsumoto , Kazuya Matsumoto , Takuro Suyama
IPC分类号： G01N21/64
CPC分类号： G01N21/643 , G01N21/6428 , G01N33/66 , Y10T436/144444
摘要： This invention relates to a sensing method and a sensing device for quantifying the concentration of an analyte by using the property that interaction between an analyte and a labeled compound changes fluorescence intensity. A fluorescence sensor is used to acquire fluorescence intensity at predetermined quantification time points. Then, the concentration of an analyte is quantified in accordance with a non-steady concentration quantification law comprising the relationship between the acquired fluorescence intensity and the time derivative quantity thereof.
摘要翻译：本发明涉及一种用于通过使用分析物和标记化合物之间的相互作用改变荧光强度的性质来定量分析物的浓度的感测方法和感测装置。荧光传感器用于在预定量化时间点获取荧光强度。然后，根据包含所获得的荧光强度与其时间衍生量之间的关系的非稳定浓度定量定律来定量分析物的浓度。

3. 发明授权

US08649836B2 Fluorescence sensor, needle-type fluorescence sensor, and method for measuring analyte 有权
标题翻译：荧光传感器，针型荧光传感器以及测定分析物的方法
公开(公告)号：US08649836B2
公开(公告)日：2014-02-11
申请号：US13271732
申请日：2011-10-12
申请人： Etsuro Shimizu , Kazuya Matsumoto , Ryo Ota , Atsushi Matsumoto
发明人： Etsuro Shimizu , Kazuya Matsumoto , Ryo Ota , Atsushi Matsumoto
IPC分类号： A61B5/1455
CPC分类号： G01N21/77 , A61B5/14532 , A61B5/1459 , G01N2021/7753 , G01N2021/7786
摘要： A needle-type fluorescence sensor that measures glucose based on fluorescence produced by excitation light is provided. The needle-type fluorescence sensor includes a needle body section including a sensor portion disposed in a needle distal end portion and metal lines disposed from the sensor portion to a needle proximal end portion, and a connector which is integrated with the needle body section and in which the metal lines extend. The sensor portion includes a silicon substrate having first and second principal surfaces, a PD device that converts fluorescence into an electric signal, an LED device that transmits fluorescence and emits excitation light, and an indicator layer that interacts with an analyte under the excitation light to produce fluorescence. The PD device, the LED device, and the indicator layer overlap with each other above the first principal surface of the silicon substrate.
摘要翻译：提供了一种根据由激发光产生的荧光测量葡萄糖的针型荧光传感器。针型荧光传感器包括：针体部，其包括设置在针前端部的传感器部和从传感器部到针基端部的金属线;以及连接器，其与针体部一体化，金属线延伸。传感器部分包括具有第一和第二主表面的硅衬底，将荧光转换为电信号的PD器件，透射荧光并发射激发光的LED器件，以及在激发光下与分析物相互作用的指示器层产生荧光。 PD器件，LED器件和指示层在硅衬底的第一主表面之上彼此重叠。

4. 发明授权

US08889844B2 Nucleic acid for treatment or prevention of immunodeficiency virus infection 有权
标题翻译：用于治疗或预防免疫缺陷病毒感染的核酸
公开(公告)号：US08889844B2
公开(公告)日：2014-11-18
申请号：US12064185
申请日：2006-08-10
申请人： Hideto Chono , Kazuya Matsumoto , Junichi Mineno , Ikunoshin Kato
发明人： Hideto Chono , Kazuya Matsumoto , Junichi Mineno , Ikunoshin Kato
IPC分类号： C07H21/00 , C12N15/00 , C12N15/86 , C12N15/867 , A61K31/7088 , C12N9/22 , C12N15/85 , C12N5/0783 , C07K14/47 , A61K48/00 , A61K38/00
CPC分类号： C12N15/86 , A61K31/7088 , A61K35/17 , A61K38/00 , A61K38/465 , A61K48/00 , C07K14/4702 , C12N5/0636 , C12N9/22 , C12N15/85 , C12N2510/00 , C12N2830/002 , Y02A50/473
摘要： A nucleic acid comprising a transcription regulation sequence whose transcription is induced by a trans-acting factor of a human immunodeficiency virus and a gene encoding a polypeptide having an endoribonuclease activity specific to single-stranded RNA, wherein the gene is located in such a position that the expression of the gene can be regulated by the transcription regulation sequence; a method for production of a cell showing an inhibited replication of a human immunodeficiency virus therein, the method comprising the step of introducing the nucleic acid into a cell; and a method for treatment or prevention of a human immunodeficiency virus infection.
摘要翻译：一种核酸，其包含其转录由人免疫缺陷病毒的反式作用因子诱导的转录调控序列和编码具有对单链RNA特异性的内切核糖核酸酶活性的多肽的基因，其中所述基因位于该基因的表达可以通过转录调控序列来调节; 一种在其中显示抑制人体免疫缺陷病毒复制的细胞的制备方法，所述方法包括将核酸引入细胞的步骤; 以及用于治疗或预防人类免疫缺陷病毒感染的方法。

5. 发明申请

US20110236905A1 METHOD FOR SCREENING CATTLE, CATTLE SCREENED, AND CATTLE SCREENING KIT 审中-公开
标题翻译：用于筛选CATTLE，CATTLE SCREENED和CATTLE SCREENING KIT的方法
公开(公告)号：US20110236905A1
公开(公告)日：2011-09-29
申请号：US12936569
申请日：2009-03-04
申请人： Kazuya Matsumoto , Kouichi Morimoto , Haruka Ikegami , Kouhei Nagai
发明人： Kazuya Matsumoto , Kouichi Morimoto , Haruka Ikegami , Kouhei Nagai
IPC分类号： G01N33/566 , C12Q1/02
CPC分类号： C07K16/18 , G01N33/68 , G01N2333/4718
摘要： There are provided a method for screening individual cattle having useful economic traits in which proteins related to the economic traits of beef cattle are identified by proteomics and are used as biomarkers, and a cattle screening kit for use in the method.The method for screening individual cattle according to the present invention includes the steps of (1) harvesting body tissue from the cattle, (2) extracting the full complement of proteins from the body tissue harvested, (3) detecting a wild-type annexin A5 protein, an isoform of the wild-type annexin A5 protein, or a modified protein of the wild-type annexin A5 protein or the isoform thereof in the full complement of proteins extracted, and (4) determining whether or not the cattle will have a high average carcass weight on the basis of the type of annexin A5 detected. The wild-type annexin A5 protein, the isoform thereof, and the modified protein thereof are detected by two-dimensional electrophoresis or an antigen-antibody reaction.
摘要翻译：提供了一种筛选具有有用的经济性状的个体牛的方法，其中通过蛋白质组学鉴定与牛的经济性状相关的蛋白质并用作生物标志物，以及用于该方法的牛筛选试剂盒。根据本发明的用于筛选个体牛的方法包括以下步骤：（1）从牛收获身体组织，（2）从收获的身体组织中提取全部蛋白质，（3）检测野生型膜联蛋白A5 蛋白质，野生型膜联蛋白A5蛋白的同种型，或野生型膜联蛋白A5蛋白的修饰蛋白或其同源物在提取的全部蛋白质中，以及（4）确定牛是否具有基于检测到膜联蛋白A5的类型的高平均胴体重。通过二维电泳或抗原 - 抗体反应检测野生型膜联蛋白A5蛋白及其同种型及其修饰蛋白。

6. 发明授权

US07952256B2 Ultrasonic transducer, ultrasonic transducer fabrication method, and ultrasonic endoscope 有权
标题翻译：超声波换能器，超声波换能器制造方法和超声波内窥镜
公开(公告)号：US07952256B2
公开(公告)日：2011-05-31
申请号：US11870786
申请日：2007-10-11
申请人： Kazuya Matsumoto , Ryo Ohta , Mamoru Hasegawa , Hideo Adachi , Katsuhiro Wakabayashi
发明人： Kazuya Matsumoto , Ryo Ohta , Mamoru Hasegawa , Hideo Adachi , Katsuhiro Wakabayashi
IPC分类号： H01L41/08
CPC分类号： A61B8/4488 , A61B8/12 , A61B8/445 , B06B1/0292 , Y10T29/42 , Y10T29/49005 , Y10T29/49155
摘要： An ultrasonic transducer according to the present invention includes: two or more ultrasonic transducer cells, each of which has a lower electrode, a first insulating layer placed on the lower electrode, a cavity placed on the first insulating layer, a second insulating layer placed on the cavity, and an upper electrode placed above the second insulating layer; channels which communicate the cavities with each other; the second insulating layer placed on the channels; holes formed in the second insulating layer placed on the channels; and sealing portions which seal the holes, where that part of the sealing portions which enters the channels is the same in cross-sectional shape as the holes.
摘要翻译：根据本发明的超声波换能器包括：两个或更多个超声波换能器单元，每个超声换能器单元具有下电极，设置在下电极上的第一绝缘层，放置在第一绝缘层上的空腔，放置在第二绝缘层上的第二绝缘层所述空腔和位于所述第二绝缘层上方的上电极; 将空腔相互通信的通道; 第二绝缘层放置在通道上; 形成在通道上的第二绝缘层中的孔; 以及密封孔的密封部分，其中进入通道的密封部分的那部分与孔的横截面形状相同。

7. 发明授权

US07589455B2 Capacitive micromachined ultrasonic transducer and production method of same 有权
标题翻译：电容式微加工超声波换能器及其制作方法
公开(公告)号：US07589455B2
公开(公告)日：2009-09-15
申请号：US11942364
申请日：2007-11-19
申请人： Hideo Adachi , Katsuhiro Wakabayashi , Kazuya Matsumoto , Ryo Ota , Masaaki Amikura , Hiroshi Ito , Mamoru Hasegawa
发明人： Hideo Adachi , Katsuhiro Wakabayashi , Kazuya Matsumoto , Ryo Ota , Masaaki Amikura , Hiroshi Ito , Mamoru Hasegawa
IPC分类号： H01L41/09
CPC分类号： A61B8/12 , A61B8/445 , A61B8/4483 , A61B2562/028 , B06B1/0292
摘要： A capacitive micromachined ultrasonic transducer (cMUT) is constituted by a plurality of transducer elements comprising plural transducer cells that are mutually connected in parallel and comprises: a silicon substrate; a bottom electrode placed on the top surface of the silicon substrate; an upper electrode placed opposite to the bottom electrode and apart therefrom by a prescribed air or vacuum; a membrane for supporting the bottom electrode; and a membrane supporting part for supporting the membrane, wherein the cMUT comprises a third electrode which has an electrical continuity to the bottom electrode and which corresponds to either one of the transducer cells of a prescribed number of the transducer subelement or of the transducer elements, and a fourth electrode which is a ground electrode electrically connected to the bottom electrode.
摘要翻译：电容微加工超声换能器（cMUT）由多个换能器元件构成，多个换能器元件包括并联的多个换能器单元，包括：硅基底; 放置在硅衬底的顶表面上的底电极; 上电极通过规定的空气或真空与底电极相对设置并与其分离; 用于支撑底部电极的膜; 以及用于支撑所述膜的膜支撑部分，其中所述cMUT包括与所述底部电极具有电连续性并且对应于规定数量的所述换能器子元件或所述换能器元件中的任一个换能器单元的第三电极，以及第四电极，其是与所述底部电极电连接的接地电极。

8. 发明申请

US20080158033A1 DRIVING DEVICE FOR IMAGE DISPLAY SYSTEM 审中-公开
标题翻译：用于图像显示系统的驱动装置
公开(公告)号：US20080158033A1
公开(公告)日：2008-07-03
申请号：US11965279
申请日：2007-12-27
申请人： Yasuyuki Doi , Makoto Hattori , Hisao Kunitani , Atsuhisa Kageyama , Tetsuro Oomori , Osamu Sarai , Tooru Suyama , Kurumi Nakayama , Kazuya Matsumoto
发明人： Yasuyuki Doi , Makoto Hattori , Hisao Kunitani , Atsuhisa Kageyama , Tetsuro Oomori , Osamu Sarai , Tooru Suyama , Kurumi Nakayama , Kazuya Matsumoto
IPC分类号： G09G3/36
CPC分类号： G09G3/3685 , G09G3/2059 , G09G3/3696 , G09G2310/027 , G09G2340/0428
摘要： A driving device for driving an image display system, which sequentially receives input image data corresponding to gradation of each pixel of a display image and outputs a driving voltage signal includes: an operation section for obtaining output image data of which a bit number is smaller than a bit number of the input image data based on input image data of a target pixel to be processed and input image data of a pixel in vicinity of the target pixel; a reference voltage generation section for generating a plurality of reference voltages of different levels; and a reference voltage selection section for selecting one of the plurality of reference voltages. The operation section is configured to obtain output image data of the target pixel so that a difference between the input image data and output image data of the target pixel and a difference between the input image data and output image data of the pixel in vicinity of the target pixel cancel out each other.
摘要翻译：一种用于驱动图像显示系统的驱动装置，其顺序地接收与显示图像的每个像素的灰度对应的输入图像数据并输出驱动电压信号，包括：操作部，用于获得位数小于基于要处理的目标像素的输入图像数据的输入图像数据的位数，并输入目标像素附近的像素的图像数据; 用于产生不同电平的多个参考电压的参考电压产生部分; 以及用于选择多个参考电压中的一个的参考电压选择部分。操作部被配置为获得目标像素的输出图像数据，使得输入图像数据和目标像素的输出图像数据之间的差异以及输入图像数据与输入图像数据之间的像素的输出图像数据之间的差异目标像素相互抵消。

9. 发明授权

US07180149B2 Semiconductor package with through-hole 有权
标题翻译：半导体封装带通孔
公开(公告)号：US07180149B2
公开(公告)日：2007-02-20
申请号：US10924205
申请日：2004-08-24
申请人： Satoshi Yamamoto , Tatsuo Suemasu , Sayaka Hirafune , Toshihiko Isokawa , Koichi Shiotani , Kazuya Matsumoto
发明人： Satoshi Yamamoto , Tatsuo Suemasu , Sayaka Hirafune , Toshihiko Isokawa , Koichi Shiotani , Kazuya Matsumoto
IPC分类号： H01L31/0203
CPC分类号： H01L24/94 , H01L21/76898 , H01L23/481 , H01L23/5389 , H01L24/48 , H01L25/0652 , H01L25/0657 , H01L27/14618 , H01L27/14632 , H01L27/14687 , H01L2224/02372 , H01L2224/0401 , H01L2224/13024 , H01L2224/451 , H01L2224/48091 , H01L2224/48227 , H01L2225/06524 , H01L2225/06541 , H01L2924/00014 , H01L2924/01004 , H01L2924/01005 , H01L2924/01006 , H01L2924/01013 , H01L2924/01015 , H01L2924/01019 , H01L2924/01023 , H01L2924/01029 , H01L2924/01033 , H01L2924/01057 , H01L2924/01067 , H01L2924/01078 , H01L2924/01079 , H01L2924/01082 , H01L2924/01322 , H01L2924/014 , H01L2924/04953 , H01L2924/10253 , H01L2924/14 , H01L2924/15153 , H01L2924/15165 , H01L2924/15788 , H01L2924/16195 , H01L2924/3025 , H01L2924/00 , H01L2224/45099
摘要： A semiconductor package of the invention comprises: a semiconductor element provided with a circuit element on one surface of a semiconductor substrate; an external wiring region provided on an other surface of the semiconductor substrate; a support substrate disposed on the one surface of the semiconductor substrate; an electrode pad disposed on the one surface of the semiconductor substrate; and a through-electrode which extends from the electrode pad through to the other surface of the semiconductor substrate.
摘要翻译：本发明的半导体封装包括：在半导体衬底的一个表面上设置有电路元件的半导体元件; 设置在所述半导体衬底的另一个表面上的外部布线区域; 支撑基板，设置在所述半导体基板的一个表面上; 设置在所述半导体衬底的一个表面上的电极焊盘; 以及从电极焊盘延伸到半导体衬底的另一个表面的贯通电极。

10. 发明授权

US07109834B2 Electromagnetic drive type actuator 有权
标题翻译：电磁驱动型执行器
公开(公告)号：US07109834B2
公开(公告)日：2006-09-19
申请号：US10791438
申请日：2004-03-02
申请人： Kazuya Matsumoto
发明人： Kazuya Matsumoto
IPC分类号： H01H51/22
CPC分类号： H02K41/0354 , H01F2007/068 , H02K2201/18
摘要： An electromagnetic drive type actuator comprises a movable plate having a flat surface, a support positioned around the movable plate, an elastic member connecting the movable plate with the support, wirings extending through the support, the movable plate and the elastic member, and a magnetic field generator. The elastic member is elastically deformable and supports the movable plate so as to allow the movable plate to move in directions parallel to the flat surface of the movable plate. The wirings pass currents. The magnetic field generator generates a magnetic field in a space around the movable plate. The magnetic field has a direction orthogonal to the flat surface of the movable plate. The movable plate is moved in the directions parallel to the flat surface of the movable plate by an interaction between the currents flowing through the wirings and the magnetic field generated by magnetic field generator.
摘要翻译：电磁驱动型致动器包括具有平坦表面的可移动板，围绕可动板的支撑件，将可移动板与支撑件连接的弹性元件，延伸穿过支撑件，可动板和弹性元件的布线，以及磁场发生器。弹性构件是可弹性变形的并且支撑可移动板，以允许可动板在平行于可动板的平坦表面的方向上移动。接线通过电流。磁场发生器在可动板周围的空间中产生磁场。磁场具有与可动板的平坦表面正交的方向。可移动板通过流过布线的电流和由磁场发生器产生的磁场之间的相互作用在平行于可动板的平坦表面的方向上移动。

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