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1. 发明授权

US08317854B1 Apparatus and methods for endoluminal graft placement 失效
标题翻译：腔内移植物放置的装置和方法
公开(公告)号：US08317854B1
公开(公告)日：2012-11-27
申请号：US08684508
申请日：1996-07-19
申请人： Timothy J. Ryan , Thomas J. Fogarty , Jay A. Lenker , Kirsten Freislinger
发明人： Timothy J. Ryan , Thomas J. Fogarty , Jay A. Lenker , Kirsten Freislinger
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/848 , A61F2/89 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2/954 , A61F2002/067 , A61F2002/072 , A61F2002/075 , A61F2002/91541 , A61F2002/91558 , A61F2002/9511 , A61F2002/9522 , A61F2002/9534 , A61F2210/0019 , A61F2220/0058 , A61F2220/0075 , A61F2230/0054 , A61F2240/001 , A61F2250/0018 , A61F2250/0019 , A61F2250/0029 , A61F2250/0039 , A61F2250/0048 , A61F2250/0098
摘要： A vascular graft comprises a perforate tubular compressible frame having a fabric liner disposed over at least a portion of the frames lumen. The graft may be used in combination with a base structure to form a bifurcated graft in situ. The base structure compresses a compressible frame having a fabric liner which defines a pair of divergent legs. The base structure is positioned within the aorta so that one leg enters each iliac. The tubular grafts can then be introduced into each leg to form the bifurcated structure. A graft delivery catheter includes a controllably flared sheath which facilitates recapture of a partially deployed graft.
摘要翻译：血管移植物包括穿孔管状可压缩框架，其具有布置在框架内腔的至少一部分上的织物衬里。移植物可以与基础结构组合使用以原位形成分叉移植物。基部结构压缩具有限定一对发散腿的织物衬里的可压缩框架。基部结构位于主动脉内，使得一条腿进入每个髂骨。然后将管状移植物引入每个腿部以形成分叉结构。移植物递送导管包括可控地扩张的护套，其有利于部分部署的移植物的再捕获。

2. 发明授权

US06562048B1 Deformable conduits and methods for shunting bodily fluid during surgery 失效
标题翻译：手术中可变形导管和分流体液的方法
公开(公告)号：US06562048B1
公开(公告)日：2003-05-13
申请号：US09708127
申请日：2000-11-07
申请人： Thomas J. Fogarty , Timothy J. Ryan
发明人： Thomas J. Fogarty , Timothy J. Ryan
IPC分类号： A61F1100
CPC分类号： A61B17/11 , A61B17/12036 , A61B17/12045 , A61B17/1227 , A61B17/30 , A61B2017/12127 , A61B2017/2944 , A61F2/06 , A61F2/064
摘要： The present invention comprises a tubular shunt for insertion into a fluid vessel in a living creature constructed of an elastically deformable material that reduces in circumference when stretched longitudinally so that the ends of the shunt may be easily inserted into openings in a blood vessel and where the material expands circumferentially when allowed to axially contract such that the ends of shunt press against the vessel wall to secure the shunt and form a water tight seal to permit fluid to flow through the tubular conduit of the shunt. A method for shunting fluid-flow in a portion of a vessel in a living creature is also disclosed wherein a shunt of the present invention is stretched longitudinally so that the ends of the shunt contract and then inserted into a lumen of a blood vessel. Following insertion of the shunt, the shunt is allowed to return to its relaxed geometry so that it forms a fluid tight seal with the interior of the lumen.
摘要翻译：本发明包括一种管状分流器，用于插入到由可弹性变形的材料构成的活体中的流体容器中，该弹性变形材料在纵向拉伸时减小了周长，使得分流器的端部可以容易地插入到血管的开口中，当允许轴向收缩时，材料周向膨胀，使得分流器的端部压靠在容器壁上以固定分流器并形成防水密封，以允许流体流过分流器的管状导管。还公开了一种用于在活体中的容器的一部分中流动流动的方法，其中本发明的分流器纵向拉伸，使得分流器的端部收缩然后插入血管的内腔。在插入分流器之后，分流器被允许返回到其松弛的几何形状，使得其与内腔的内部形成流体密封的密封。

3. 发明授权

US6042581A Transvascular TMR device and method 失效
标题翻译：血管内TMR装置及方法
公开(公告)号：US6042581A
公开(公告)日：2000-03-28
申请号：US745869
申请日：1996-11-08
申请人： Timothy J. Ryan , Thomas J. Fogarty
发明人： Timothy J. Ryan , Thomas J. Fogarty
IPC分类号： A61B1/00 , A61B17/00 , A61B18/14 , A61B18/22 , A61B18/24 , A61B17/39
CPC分类号： A61B18/24 , A61B18/1492 , A61B1/00165 , A61B17/32 , A61B18/1477 , A61B2017/00247 , A61B2017/00252 , A61B2017/003 , A61B2017/00703 , A61B2017/22038 , A61B2018/00011 , A61B2018/00208 , A61B2018/0022 , A61B2018/00392 , A61B2018/1253 , A61B2018/126 , A61B2018/1425 , A61B2018/162 , A61B2018/1861 , A61B2018/2238 , A61B2090/3782 , A61B2218/002 , A61B2218/007
摘要： A catheter assembly for performing transmyocardial revascularization through the coronary arteries or veins, and a method of using this assembly for creating TMR channels through the myocardium coronary artery shunts through the myocardium.
摘要翻译：用于通过冠状动脉或静脉进行经心肌血运重建的导管组件，以及使用该组件通过心肌冠状动脉分离心肌形成TMR通道的方法。

4. 发明授权

US08206427B1 Apparatus and methods for endoluminal graft placement 失效
标题翻译：腔内移植物放置的装置和方法
公开(公告)号：US08206427B1
公开(公告)日：2012-06-26
申请号：US08463836
申请日：1995-06-05
申请人： Timothy J. Ryan , Thomas J. Fogarty , Jay A. Lenker , Kirsten Freislinger
发明人： Timothy J. Ryan , Thomas J. Fogarty , Jay A. Lenker , Kirsten Freislinger
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/848 , A61F2/89 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2/954 , A61F2002/067 , A61F2002/072 , A61F2002/075 , A61F2002/91541 , A61F2002/91558 , A61F2002/9511 , A61F2002/9522 , A61F2002/9534 , A61F2210/0019 , A61F2220/0058 , A61F2220/0075 , A61F2230/0054 , A61F2240/001 , A61F2250/0018 , A61F2250/0019 , A61F2250/0029 , A61F2250/0039 , A61F2250/0048 , A61F2250/0098
摘要： A vascular graft comprises a perforate tubular compressible frame having a fabric liner disposed over at least a portion of the frames lumen. The graft may be used in combination with a base structure to form a bifurcated graft in situ. The base structure compresses a compressible frame having a fabric liner which defines a pair of divergent legs. The base structure is positioned within the aorta so that one leg enters each iliac. The tubular grafts can then be introduced into each leg to form the bifurcated structure. A graft delivery catheter includes a controllably flared sheath which facilitates recapture of a partially deployed graft.
摘要翻译：血管移植物包括穿孔管状可压缩框架，其具有设置在框架腔的至少一部分上的织物衬里。移植物可以与基础结构组合使用以原位形成分叉移植物。基部结构压缩具有限定一对发散腿的织物衬里的可压缩框架。基部结构位于主动脉内，使得一条腿进入每个髂骨。然后将管状移植物引入每个腿部以形成分叉结构。移植物递送导管包括可控地扩张的护套，其有利于部分部署的移植物的再捕获。

5. 发明授权

US06168623A Deformable conduits and methods for shunting bodily fluid during surgery 失效
标题翻译：手术中可变形导管和分流体液的方法
公开(公告)号：US06168623A
公开(公告)日：2001-01-02
申请号：US09143995
申请日：1998-08-31
申请人： Thomas J. Fogarty , Timothy J. Ryan
发明人： Thomas J. Fogarty , Timothy J. Ryan
IPC分类号： A61F200
CPC分类号： A61B17/11 , A61B17/12036 , A61B17/12045 , A61B17/1227 , A61B17/30 , A61B2017/12127 , A61B2017/2944 , A61F2/06 , A61F2/064
摘要： The present invention comprises a tubular shunt for insertion into a fluid vessel in a living creature constructed of an elastically deformable material that reduces in circumference when stretched longitudinally so that the ends of the shunt may be easily inserted into openings in a blood vessel and where the material expands circumferentially when allowed to axially contract such that the ends of shunt press against the vessel wall to secure the shunt and form a water tight seal to permit fluid to flow through the tubular conduit of the shunt. A method for shunting fluid-flow in a portion of a vessel in a living creature is also disclosed wherein a shunt of the present invention is stretched longitudinally so that the ends of the shunt contract and then inserted into a lumen of a blood vessel. Following insertion of the shunt, the shunt is allowed to return to its relaxed geometry so that it forms a fluid tight seal with the interior of the lumen.
摘要翻译：本发明包括一种管状分流器，用于插入到由可弹性变形的材料构成的活体中的流体容器中，该弹性变形材料在纵向拉伸时减小了周长，使得分流器的端部可以容易地插入到血管的开口中，当允许轴向收缩时，材料周向膨胀，使得分流器的端部压靠在容器壁上以固定分流器并形成防水密封，以允许流体流过分流器的管状导管。还公开了一种用于在活体中的容器的一部分中流动流动的方法，其中本发明的分流器纵向拉伸，使得分流器的端部收缩然后插入血管的内腔。在插入分流器之后，分流器被允许返回到其松弛的几何形状，使得其与内腔的内部形成流体密封的密封。

6. 发明授权

US5464449A Internal graft prosthesis and delivery system 失效
公开(公告)号：US5464449A
公开(公告)日：1995-11-07
申请号：US89290
申请日：1993-07-08
申请人： Timothy J. Ryan , Thomas J. Fogarty , Kenneth H. Mollenauer
发明人： Timothy J. Ryan , Thomas J. Fogarty , Kenneth H. Mollenauer
IPC分类号： A61F2/06 , A61F2/08
CPC分类号： A61F2/07 , A61F2/954 , A61F2/97 , A61F2/848 , A61F2/90 , A61F2002/061 , A61F2002/9511 , A61F2002/9517 , A61F2002/9534 , A61F2220/0016 , A61F2220/0075
摘要： A resilient tubular graft is delivered into place within a body passage by elongating the graft to reduce its diameter and then directing the graft to the desired position while in the elongated condition. The graft is carried into position by a pair of elongate members mounted for longitudinal movement relative to one other. Flexible lines secure opposite ends of the graft to the respective elongate members whereby relative longitudinal movement of the members functions to elongate the graft and reduce its diameter. The lines extend around the graft to impart radial compression thereto simultaneously with elongation of the graft. Upon placement of the graft at the desired location within a body passage, the lines are released to permit the graft to expand into engagement with the passage. Barbs on the graft provide for secure engagement of the graft with a body passage.

7. 发明授权

US06565555B1 Transvascular TMR device and method 有权
公开(公告)号：US06565555B1
公开(公告)日：2003-05-20
申请号：US09557628
申请日：2000-04-25
申请人： Timothy J. Ryan , Thomas J. Fogarty
发明人： Timothy J. Ryan , Thomas J. Fogarty
IPC分类号： A61B1818
CPC分类号： A61B18/24 , A61B1/00165 , A61B17/32 , A61B18/1477 , A61B18/1492 , A61B2017/00247 , A61B2017/00252 , A61B2017/003 , A61B2017/00703 , A61B2017/22038 , A61B2018/00011 , A61B2018/00208 , A61B2018/0022 , A61B2018/00392 , A61B2018/1253 , A61B2018/126 , A61B2018/1425 , A61B2018/162 , A61B2018/1861 , A61B2018/2238 , A61B2090/3782 , A61B2218/002 , A61B2218/007
摘要： A catheter assembly for performing transmyocardial revascularization through the coronary arteries or veins, and a method of using this assembly for creating TMR channels through the myocardium coronary artery shunts through the myocardium and a device and method for injecting therapeutic agents into TMR channels interoperatively, together with a number of therapeutic agents.

8. 发明授权

US5928164A Apparatus for automated biopsy and collection of soft tissue 失效
标题翻译：用于自动活检和收集软组织的装置
公开(公告)号：US5928164A
公开(公告)日：1999-07-27
申请号：US4737
申请日：1998-01-09
申请人： Fred H. Burbank , Thomas J. Fogarty , Wayne E. Manska , Mark A. Ritchart , Timothy J. Ryan , Elias A. Zerhouni
发明人： Fred H. Burbank , Thomas J. Fogarty , Wayne E. Manska , Mark A. Ritchart , Timothy J. Ryan , Elias A. Zerhouni
IPC分类号： A61B10/02 , A61B10/00 , A61B17/22 , A61B17/30 , A61B17/34 , A61B5/00
CPC分类号： A61B10/0266 , A61B10/0275 , A61B10/0283 , A61B17/221 , A61B2010/0208 , A61B2010/0225 , A61B2017/303
摘要： A method and device for the automated biopsy and collection of soft tissue having a piercing needle with a receiving port to trap tissue prior to cutting. A motor drive directs and positions the tissue receiving port at a lesion site in arbitrary positions about and along the longitudinal axis of the device. A cutter advances into the receiving chamber and severs tissue which has prolapsed into the receiving port. The severed tissue is then removed from the receiving port without removing the piercing needle receiving port from the lesion site, thus allowing for the accurate, rapid removal of an arbitrary number of core samples with only one insertion. A tissue sample cassette provides storage for the samples as well as a means for coding and decoding the location from which the samples were obtained. Together, these features allow for more accurate and complete sampling of large lesions, for the complete removal of small lesions or removal of other tissue for a variety of reasons.
摘要翻译：一种用于自动活检和收集软组织的方法和装置，其具有带有接收端口的穿刺针，以在切割之前捕获组织。马达驱动器将组织接收端口引导并定位在病变位置处，并且沿着装置的纵向轴线的任意位置。切割器进入接收室并切断已经脱垂到接收端口中的组织。然后将切断的组织从接收端口移除而不从病变部位移除穿刺针接收端口，从而允许仅用一个插入准确，快速地去除任意数量的芯样品。组织样品盒为样品提供储存，以及用于编码和解码获得样品的位置的装置。一起，这些特征允许对于大的病变进行更准确和完整的取样，用于由于各种原因完全去除小损伤或去除其他组织。

9. 发明授权

US06533811B1 Internal graft prosthesis and delivery system 失效
标题翻译：内部移植假体和输送系统
公开(公告)号：US06533811B1
公开(公告)日：2003-03-18
申请号：US08854089
申请日：1997-05-09
申请人： Timothy J. Ryan , Thomas J. Fogarty , Kenneth H. Mollenauer
发明人： Timothy J. Ryan , Thomas J. Fogarty , Kenneth H. Mollenauer
IPC分类号： A61F206
CPC分类号： A61F2/07 , A61F2/848 , A61F2/90 , A61F2/954 , A61F2/97 , A61F2002/061 , A61F2002/9511 , A61F2002/9517 , A61F2002/9534 , A61F2220/0016 , A61F2220/0075
摘要： A resilient tubular graft is delivered into place within a body passage by elongating the graft to reduce its diameter and then directing the graft to the desired position while in the elongated condition. The graft is carried into position by a pair of elongate members mounted for longitudinal movement relative to one other. Flexible lines secure opposite ends of the graft to the respective elongate members whereby relative longitudinal movement of the members functions to elongate the graft and reduce its diameter. The lines extend around the graft to impart radial compression thereto simultaneously with elongation of the graft. Upon placement of the graft at the desired location within a body passage, the lines are released to permit the graft to expand into engagement with the passage. Barbs on the graft provide for secure engagement of the graft with a body passage.
摘要翻译：将弹性管状移植物通过伸长移植物以减小其直径，然后在伸长的状态下将移植物引导到期望的位置，将其递送到体内通道内的适当位置。通过一对相对于彼此纵向运动安装的细长构件将移植物运送到位。柔性线将移植物的相对端固定到相应的细长构件，由此构件的相对纵向移动用于伸长移植物并减小其直径。线条围绕移植物延伸以在移植物的伸长的同时向其施加径向压缩。在将移植物放置在体内通道内的期望位置时，释放线以允许移植物膨胀成与通道接合。移植物上的倒钩提供移植物与身体通道的牢固接合。

10. 发明授权

US5980469A Method and apparatus for automated biopsy and collection of soft tissue 失效
标题翻译：用于软组织自动活检和收集的方法和装置
公开(公告)号：US5980469A
公开(公告)日：1999-11-09
申请号：US4782
申请日：1998-01-09
申请人： Fred H. Burbank , Thomas J. Fogarty , Wayne E. Manska , Mark A. Ritchart , Timothy J. Ryan , Elias A. Zerhouni
发明人： Fred H. Burbank , Thomas J. Fogarty , Wayne E. Manska , Mark A. Ritchart , Timothy J. Ryan , Elias A. Zerhouni
IPC分类号： A61B10/02 , A61B10/00 , A61B17/22 , A61B17/30 , A61B17/34
CPC分类号： A61B10/0266 , A61B10/0275 , A61B10/0283 , A61B17/221 , A61B2010/0208 , A61B2010/0225 , A61B2017/303
摘要： A method and device for the automated biopsy and collection of soft tissue having a piercing needle with a receiving port to trap tissue prior to cutting. A motor drive directs and positions the tissue receiving port at a lesion site in arbitrary positions about and along the longitudinal axis of the device. A cutter advances into the receiving chamber and severs tissue which has prolapsed into the receiving port. The severed tissue is then removed from the receiving port without removing the piercing needle receiving port from the lesion site, thus allowing for the accurate, rapid removal of an arbitrary number of core samples with only one insertion. A tissue sample cassette provides storage for the samples as well as a means for coding and decoding the location from which the samples were obtained. Together, these features allow for more accurate and complete sampling of large lesions, for the complete removal of small lesions or removal of other tissue for a variety of reasons.
摘要翻译：一种用于自动活检和收集软组织的方法和装置，其具有带有接收端口的穿刺针，以在切割之前捕获组织。马达驱动器将组织接收端口引导并定位在病变位置处，并且沿着装置的纵向轴线的任意位置。切割器进入接收室并切断已经脱垂到接收端口中的组织。然后将切断的组织从接收端口移除而不从病变部位移除穿刺针接收端口，从而允许仅用一个插入准确，快速地去除任意数量的芯样品。组织样品盒为样品提供储存，以及用于编码和解码获得样品的位置的装置。一起，这些特征允许对于大的病变进行更准确和完整的取样，用于由于各种原因完全去除小损伤或去除其他组织。

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