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1. 发明授权

US08039247B2 Method of forming planar lipid double membrane for membrane protein analysis and apparatus therefor 有权
标题翻译：形成用于膜蛋白分析的平面脂质双膜的方法及其装置
公开(公告)号：US08039247B2
公开(公告)日：2011-10-18
申请号：US10586331
申请日：2005-01-19
申请人： Shoji Takeuchi , Hiroaki Suzuki , Hiroyuki Noji
发明人： Shoji Takeuchi , Hiroaki Suzuki , Hiroyuki Noji
IPC分类号： C12M1/34 , G01N1/28
CPC分类号： B01L3/5088 , B01J2219/00317 , B01J2219/00585 , B01J2219/00599 , B01J2219/00653 , B01J2219/00725 , B01L3/5027 , B01L2300/0819 , B01L2400/0472
摘要： To provide a method of forming a planar lipid-bilayer membrane for membrane protein analysis, by which downsizing, simplifying, and multichanneling of a device therefore are achieved. A planar lipid-bilayer membrane 24 is formed by filling a microchannel 12 with a buffer solution 18, the microchannel 12 disposed under a horizontal partition wall 13 having an aperture 14; applying a small amount of a lipid solution 20 as a droplet on the aperture 14 filled with the buffer solution 18 to thereby form a thin layer 21 of the lipid solution in a chamber, the chamber 17 being formed at a position corresponding to the aperture 14 and provided with a liquid trap 15 inside the chamber; and applying a buffer solution 23 as a droplet to the chamber 17 from the upper side of the chamber.
摘要翻译：提供一种形成用于膜蛋白分析的平面脂双层膜的方法，由此实现了装置的小型化，简化和多元化。通过用缓冲溶液18填充微通道12形成平面脂双层膜24，微通道12设置在具有孔14的水平分隔壁13的下方; 在填充有缓冲溶液18的孔14上施加少量作为液滴的脂质溶液20，从而在腔室中形成脂质溶液的薄层21，室17形成在对应于孔14的位置并在室内设置有液体捕集器15; 并且从室的上侧将作为液滴的缓冲溶液23施加到室17。

2. 发明申请

US20100147450A1 METHOD OF FORMING BILAYER MEMBRANE BY CONTACT BETWEEN AMPHIPATHIC MONOLAYERS AND APPARATUS THEREFOR 有权
标题翻译：通过大孔单体与其设备之间的接触形成双层膜的方法
公开(公告)号：US20100147450A1
公开(公告)日：2010-06-17
申请号：US11997058
申请日：2006-07-26
申请人： Shoji Takeuchi , Hiroaki Suzuki , Kei Funakoshi
发明人： Shoji Takeuchi , Hiroaki Suzuki , Kei Funakoshi
IPC分类号： B29C65/70 , B32B37/02 , B32B38/00
CPC分类号： G01N33/92 , B01L3/502769 , G01N33/68
摘要： The present invention provides a simple and an accurate method of forming a bilayer membrane by the contact of amphipathic monolayers and an apparatus therefor. The method is characterized in that the organic solvent (2) containing lipid molecules is introduced into a first microchannel (1) formed on a substrate (5). A liquid (4) immiscible with the organic solvent (2) containing lipid molecules is introduced into a second microchannel (3), which crosses the first microchannel (1) from both sides to form an intersection, from both ends of the second microchannel (3) toward the intersection. Amphipathic monolayers (2A) opposing each other are formed at the interfaces between the liquid (4) and the organic solvent (2), and finally a lipid bilayer membrane (2B) is obtained by bringing the amphipathic monolayers (2A) into contact and fusing, by the contact of the interfaces of the liquid (4) introduced from the both ends of the second microchannel (3) with the control of the pressure of the liquid (4) using syringe pumps.
摘要翻译：本发明提供了通过两亲性单层接触形成双层膜的简单且精确的方法及其装置。该方法的特征在于，将含有脂质分子的有机溶剂（2）引入到形成在基板（5）上的第一微通道（1）中。将含有脂质分子的有机溶剂（2）不混溶的液体（4）被引入第二微通道（3），第二微通道（3）从两侧穿过第一微通道（1）以形成交叉点，从第二微通道 3）朝向十字路口。在液体（4）和有机溶剂（2）之间的界面处形成彼此相对的两亲性单层（2A），最后通过使两亲性单层（2A）接触和融合获得脂质双层膜（2B）通过从第二微通道（3）的两端引入的液体（4）的界面与使用注射泵的液体（4）的压力的控制接触。

3. 发明授权

US08513165B2 Planar lipid bilayer array formed by microfluidic technique and method of analysis using planar lipid bilayer 有权
标题翻译：通过微流体技术形成的平面脂质双层阵列和使用平面脂双层的分析方法
公开(公告)号：US08513165B2
公开(公告)日：2013-08-20
申请号：US12744794
申请日：2008-11-26
申请人： Shoji Takeuchi , Hiroaki Suzuki , Sadao Ota , Wei-Heong Tan
发明人： Shoji Takeuchi , Hiroaki Suzuki , Sadao Ota , Wei-Heong Tan
IPC分类号： C40B60/00 , C12M1/34
CPC分类号： C40B60/00 , B01L3/5027 , B01L3/502738 , B01L2200/0605 , B01L2200/0642 , B01L2200/0673 , B01L2300/041 , B01L2300/0864 , B01L2400/0487 , G01N33/54306 , G01N33/54366 , G01N33/92 , G01N2405/04
摘要： There is provided a planar lipid bilayer array formed by microfluidic technique and a method of analysis using the planar lipid bilayers, providing the advantages such as portability, decreased analysis time, a smaller amount of required reagents, and parallel automation with high reproducibility. The planar lipid bilayer array formed by microfluidic technique is a planar lipid bilayer array formed by microfluidic technique (PDMS device) 1 saturated with water by preliminarily immersing in water, comprising microchannels 2 connected to an inlet of a microfluidic channel and arranged in parallel, and microchambers 3 having apertures on both sides of the microchannel 2.
摘要翻译：提供了通过微流控技术形成的平面脂质双层阵列和使用平面脂双层的分析方法，提供了便携性，降低的分析时间，较少量的所需试剂和具有高再现性的并行自动化的优点。通过微流体技术形成的平面脂双层阵列是通过预先浸入水中的通过微水洗技术（PDMS装置）1形成的平面脂双层阵列，其包括连接到微流体通道的入口并平行布置的微通道2，以及微通道3在微通道2的两侧具有孔。

4. 发明授权

US08506905B2 Method of forming bilayer membrane by contact between amphipathic monolayers and apparatus therefor 有权
标题翻译：通过两亲性单层之间的接触形成双层膜的方法及其设备
公开(公告)号：US08506905B2
公开(公告)日：2013-08-13
申请号：US11997058
申请日：2006-07-26
申请人： Shoji Takeuchi , Hiroaki Suzuki , Kei Funakoshi
发明人： Shoji Takeuchi , Hiroaki Suzuki , Kei Funakoshi
IPC分类号： B01L3/00 , G01N1/16 , G01N31/20 , B01D11/00 , B01D35/00
CPC分类号： G01N33/92 , B01L3/502769 , G01N33/68
摘要： The present invention provides simple and an accurate apparatuses for forming bilayer membranes by the contact of amphipathic monolayers. In one apparatus, amphipathic monolayers are brought into contact and fused by controlling the pressure of liquids introduced from microchannels forming an intersection containing a chamber. In another apparatus, the chamber includes a number of compartments and at least one construction portion. In this apparatus, a droplet is formed within each compartment and contact of amphipatic monolayers is accomplished by adjusting the size of the droplets.
摘要翻译：本发明提供了通过两亲性单层接触形成双层膜的简单且准确的装置。在一个装置中，通过控制从形成包含室的交点的微通道引入的液体的压力，使两亲性单层接触并熔融。在另一装置中，腔室包括多个隔间和至少一个结构部分。在该装置中，在每个室内形成液滴，并通过调节液滴的尺寸来实现两相单层的接触。

5. 发明申请

US20100304980A1 PLANAR LIPID BILAYER ARRAY FORMED BY MICROFLUIDIC TECHNIQUE AND METHOD OF ANALYSIS USING PLANAR LIPID BILAYER 有权
标题翻译：通过微流控技术形成的平面脂质双层阵列和使用平面脂质双层分析的方法
公开(公告)号：US20100304980A1
公开(公告)日：2010-12-02
申请号：US12744794
申请日：2008-11-26
申请人： Shoji Takeuchi , Hiroaki Suzuki , Sadao Ota , Wei-Heong Tan
发明人： Shoji Takeuchi , Hiroaki Suzuki , Sadao Ota , Wei-Heong Tan
IPC分类号： C40B30/00 , C40B40/04
CPC分类号： C40B60/00 , B01L3/5027 , B01L3/502738 , B01L2200/0605 , B01L2200/0642 , B01L2200/0673 , B01L2300/041 , B01L2300/0864 , B01L2400/0487 , G01N33/54306 , G01N33/54366 , G01N33/92 , G01N2405/04
摘要： There is provided a planar lipid bilayer array formed by microfluidic technique and a method of analysis using the planar lipid bilayers, providing the advantages such as portability, decreased analysis time, a smaller amount of required reagents, and parallel automation with high reproducibility. The planar lipid bilayer array formed by microfluidic technique is a planar lipid bilayer array formed by microfluidic technique (PDMS device) 1 saturated with water by preliminarily immersing in water, comprising microchannels 2 connected to an inlet of a microfluidic channel and arranged in parallel, and microchambers 3 having apertures on both sides of the microchannel 2.
摘要翻译：提供了通过微流控技术形成的平面脂质双层阵列和使用平面脂双层的分析方法，提供了便携性，降低的分析时间，较少量的所需试剂和具有高再现性的并行自动化的优点。通过微流体技术形成的平面脂双层阵列是通过预先浸入水中的通过微水洗技术（PDMS装置）1形成的平面脂双层阵列，其包括连接到微流体通道的入口并平行布置的微通道2，以及微通道3在微通道2的两侧具有孔。

6. 发明授权

US09606494B2 Printing control device and printing control system that generate toner-scattering prevention plane data 有权
公开(公告)号：US09606494B2
公开(公告)日：2017-03-28
申请号：US14483745
申请日：2014-09-11
申请人： Yuji Kogusuri , Takanori Itoh , Yuichi Habu , Hiroaki Suzuki
发明人： Yuji Kogusuri , Takanori Itoh , Yuichi Habu , Hiroaki Suzuki
IPC分类号： G03G15/08 , G03G15/00
CPC分类号： G03G15/6585 , G03G2215/0129
摘要： A printing control device includes a toner-scattering prevention plane generating unit that generates toner-scattering prevention plane data indicating that clear toner is applied to an outline drawing that is identified from target data for print; and an image-data generating unit that generates image data that includes the outline drawing by using the toner-scattering prevention plane data.

7. 发明授权

US09385389B2 Fuel cell 有权
标题翻译：燃料电池
公开(公告)号：US09385389B2
公开(公告)日：2016-07-05
申请号：US14112753
申请日：2012-05-16
申请人： Goro Fujita , Hiroaki Suzuki
发明人： Goro Fujita , Hiroaki Suzuki
IPC分类号： H01M8/10
CPC分类号： H01M8/1065 , H01M8/1067 , Y02E60/521
摘要： An electrolyte membrane 22 constituting a membrane electrode assembly includes thick portions 23 having a relatively large thickness. The thick portions 23 have a strip shape and are disposed at a predetermined distance from each other along the electric conduction direction. The thick portions 23 extend from one side L1 of the electrolyte membrane 22 extending in a direction perpendicular to the electric conduction direction to the other side L2 of the electrolyte membrane 22 extending in the direction perpendicular to the electric conduction direction. The thick portions 23 have a convex shape with respect to the anode side surface and the cathode side surface of the electrolyte membrane 22.
摘要翻译：构成膜电极组件的电解质膜22包括厚度较大的厚壁部23。厚壁部23为带状，沿着导电方向彼此隔开规定距离。厚部23从与导电方向垂直的方向延伸的电解质膜22的一侧L1延伸到与导电方向垂直的方向延伸的电解质膜22的另一侧L2。厚壁部23相对于电解质膜22的阳极侧面和阴极侧面呈凸形。

8. 发明授权

US09344604B2 Display processing apparatus correcting color saturation due to gloss, image forming system, and computer program product 有权
标题翻译：显示处理装置校正由于光泽，图像形成系统和计算机程序产品引起的色彩饱和度
公开(公告)号：US09344604B2
公开(公告)日：2016-05-17
申请号：US13610572
申请日：2012-09-11
申请人： Ryonosuke Miyazaki , Hiroaki Suzuki
发明人： Ryonosuke Miyazaki , Hiroaki Suzuki
IPC分类号： H04N1/54 , H04N1/60
CPC分类号： H04N1/54 , H04N1/6011
摘要： A display processing apparatus includes a first correcting unit that, based on original data containing first-type color image data that indicates a color image in each drawing area and containing first-type gloss control image data that indicates a type of gloss effect to be given to a recording medium and indicates a gloss area to which the gloss effect is to be given in each drawing area, corrects color saturation of an area in the first-type color image data that corresponds to the gloss area specified by the first-type gloss control image data depending on the type of gloss effect, to thereby generate first-type corrected image data; and a display control unit that, on a display unit, displays the first-type corrected image data as a print preview of a projected printing result of the original data.
摘要翻译：显示处理装置包括：第一校正单元，其基于包含指示每个绘图区域中的彩色图像的第一类型彩色图像数据的原始数据，并且包含指示要给出的光泽效果的类型的第一类型光泽控制图像数据并且指示在每个绘图区域中给予光泽效果的光泽区域，校正与由第一类型光泽指定的光泽区域相对应的第一类型彩色图像数据中的区域的颜色饱和度根据光泽效果的类型控制图像数据，从而生成第一类型校正图像数据; 以及显示控制单元，其在显示单元上显示所述第一类型校正图像数据作为所述原始数据的投影打印结果的打印预览。

9. 发明授权

US09291979B2 Device, system, method, and recording medium having computer program for controlling printing 有权
标题翻译：具有用于控制打印的计算机程序的装置，系统，方法和记录介质
公开(公告)号：US09291979B2
公开(公告)日：2016-03-22
申请号：US14578871
申请日：2014-12-22
申请人： Makoto Yoshida , Hiroaki Suzuki
发明人： Makoto Yoshida , Hiroaki Suzuki
IPC分类号： G03G15/00 , G03G15/01
CPC分类号： G03G15/6585 , G03G15/0105 , G03G15/657
摘要： A printing control device includes a glossiness target value determining unit that determines a glossiness target value indicating a target of glossiness of image data as a print target, a color separation amount determining unit that determines color separation amounts of a plurality of colored color materials as amounts of the colored color materials to be allocated to the respective colored color materials based on a sum of respective amounts of the colored color materials for the glossiness target value, a color separation processing unit that executes color replacement among a plurality of pieces of colored plane data based on the color separation amounts of the respective colored color materials, and an image data generator that generates the image data based on the pieces of colored plane data on which the color replacement has been executed.
摘要翻译：打印控制装置包括：光泽度目标值确定单元，其确定指示作为打印对象的图像数据的光泽度的目标的光泽度目标值;颜色分离量确定单元，其将多个着色色素的颜色分离量确定为量基于用于光泽度目标值的彩色着色材料的相应量的总和，分配给各个着色色材料的着色色材料的色分离处理单元在多条彩色平面数据之间执行颜色替换基于各色着色材料的颜色分离量，以及基于执行了颜色替换的彩色平面数据生成图像数据的图像数据生成器。

10. 发明授权

US09177233B2 Display processing apparatus, image forming system, and computer-readable storage medium 有权
标题翻译：显示处理装置，图像形成系统和计算机可读存储介质
公开(公告)号：US09177233B2
公开(公告)日：2015-11-03
申请号：US14339604
申请日：2014-07-24
申请人： Ryonosuke Miyazaki , Tomoyoshi Takeuchi , Yasushi Yamaguchi , Hiroaki Suzuki
发明人： Ryonosuke Miyazaki , Tomoyoshi Takeuchi , Yasushi Yamaguchi , Hiroaki Suzuki
IPC分类号： H04N1/40 , G06K15/02 , G03G15/00 , G06F3/12
CPC分类号： G06K15/1889 , G03G15/502 , G03G15/6585 , G03G2215/00805 , G06F3/1208 , G06K15/1886
摘要： A display processing apparatus includes a receiving unit configured to receive display information indicating whether gloss-control plane image data is displayed and whether clear plane image data is displayed. The gloss-control plane image data specifies a type of a surface effect applied to a recording medium and a glossy area to which the surface effect is to be applied, and indicates a color of the glossy area when being displayed. The clear plane image data specifies a transparent image formed on the recording medium and indicates a color of the transparent image when being displayed. The apparatus also includes a generating unit configured to synthesize color plane image data indicating a color image and one of the gloss-control plane image data and the clear plane image data that is specified to be displayed thus to generate a synthetic image.
摘要翻译：显示处理装置包括接收单元，被配置为接收指示是否显示光泽度控制平面图像数据的显示信息以及是否显示清晰平面图像数据。光泽度控制平面图像数据指定施加到记录介质的表面效果的类型和要施加表面效果的光泽区域，并且在显示时指示光泽区域的颜色。透明平面图像数据指定形成在记录介质上的透明图像，并且在显示时指示透明图像的颜色。该装置还包括：生成单元，被配置为合成指示彩色图像的彩色平面图像数据和指定为显示的光泽度控制平面图像数据和清晰平面图像数据之一，以生成合成图像。

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