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    • 1. 发明授权
    • Optical reaction cell and light source for �18F! fluoride radiotracer
synthesis
    • 用于[18F]氟化物放射性示踪剂合成的光学反应池和光源
    • US5808020A
    • 1998-09-15
    • US694398
    • 1996-08-12
    • Richard A. FerrieriDavid SchlyerRichard J. Becker
    • Richard A. FerrieriDavid SchlyerRichard J. Becker
    • B01J19/00B01J19/12B01J19/24C07H9/02B01J19/08C07H1/00C07H5/02
    • B01J19/0006B01J19/128B01J19/24C07H9/02B01J2219/00063B01J2219/00146B01J2219/00164
    • Apparatus for performing organic synthetic reactions, particularly no-carrier-added nucleophilic radiofluorination reactions for PET radiotracer production. The apparatus includes an optical reaction cell and a source of broadband infrared radiant energy, which permits direct coupling of the emitted radiant energy with the reaction medium to heat the reaction medium. Preferably, the apparatus includes means for focusing the emitted radiant energy into the reaction cell, and the reaction cell itself is preferably configured to reflect transmitted radiant energy back into the reaction medium to further improve the efficiency of the apparatus. The apparatus is well suited to the production of high-yield syntheses of 2-�.sup.18 F!fluoro-2-deoxy-D-glucose. Also provided is a method for performing organic synthetic reactions, including the manufacture of �.sup.18 F!-labeled compounds useful as PET radiotracers, and particularly for the preparation of 2-�.sup.18 F!fluoro-2-deoxy-D-glucose in higher yields than previously possible.
    • 用于进行有机合成反应的装置,特别是用于PET放射性示踪剂生产的无载体添加的亲核放射性氟化反应。 该装置包括光学反应池和宽带红外辐射能源,其允许所发射的辐射能与反应介质直接耦合以加热反应介质。 优选地,该装置包括用于将发射的辐射能聚焦到反应池中的装置,并且反应池本身优选地构造成将透射的辐射能量反射回反应介质中,以进一步提高装置的效率。 该装置非常适用于生产2- [18 F]氟-2-脱氧-D-葡萄糖的高产率合成。 还提供了用于进行有机合成反应的方法,包括制备可用作PET放射性示踪剂的[18 F]标记化合物,特别是制备2- [18 F]氟-2-脱氧-D-葡萄糖,产率高于 以前可能的
    • 5. 发明授权
    • Rotating rectifier assembly
    • 旋转整流器组件
    • US4959572A
    • 1990-09-25
    • US371362
    • 1989-06-26
    • Richard J. Becker
    • Richard J. Becker
    • H02K11/04
    • H02K11/042
    • Apparatus and method for electrically interconnecting in and supporting the rectifier components a rotating rectifier assembly. An exciter rotor and the rectifier assembly are disposed about a generator shaft. In an embodiment providing full wave rectification, the rectifier assembly has a substrate having rectifiers mounted in a rectifying circuit on two exposed conductive areas. An ac lead extends from each of the ac windings in the exciter rotor to the rotating rectifier assembly. A bus bar has a bar section secured to adjacent rectifiers. The bus bar further has a tab section adapted to receive one ac lead extending from the bar section. A support ring is disposed about the generator shaft and secured to the recifier substrate, as well as the exciter rotor. The tab section from each of the bus bars is wrapped around the inner sleeve of the ring so that the centrifical forces exerted on the bus bars during the rotation of the shaft are opposed by the inner sleeve of the ring.
    • 用于将整流器组件电连接并支撑整流器组件的旋转整流器组件的装置和方法。 励磁机转子和整流器组件围绕发电机轴设置。 在提供全波整流的实施例中,整流器组件具有衬底,其具有安装在两个暴露的导电区域上的整流电路中的整流器。 交流引线从励磁机转子中的每个交流绕组延伸到旋转整流器组件。 母线具有固定在相邻整流器上的条形部分。 母线还具有接片部分,适于接收从杆部延伸的一个交流导线。 支撑环设置在发电机轴周围并固定到再生器基板以及励磁机转子。 来自每个母线的突片部分缠绕在环的内套筒上,使得在轴的旋转期间施加在母线上的离心力与环的内套筒相对。