专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US5808020A Optical reaction cell and light source for �18F! fluoride radiotracer synthesis 失效
标题翻译：用于[18F]氟化物放射性示踪剂合成的光学反应池和光源
公开(公告)号：US5808020A
公开(公告)日：1998-09-15
申请号：US694398
申请日：1996-08-12
申请人： Richard A. Ferrieri , David Schlyer , Richard J. Becker
发明人： Richard A. Ferrieri , David Schlyer , Richard J. Becker
IPC分类号： B01J19/00 , B01J19/12 , B01J19/24 , C07H9/02 , B01J19/08 , C07H1/00 , C07H5/02
CPC分类号： B01J19/0006 , B01J19/128 , B01J19/24 , C07H9/02 , B01J2219/00063 , B01J2219/00146 , B01J2219/00164
摘要： Apparatus for performing organic synthetic reactions, particularly no-carrier-added nucleophilic radiofluorination reactions for PET radiotracer production. The apparatus includes an optical reaction cell and a source of broadband infrared radiant energy, which permits direct coupling of the emitted radiant energy with the reaction medium to heat the reaction medium. Preferably, the apparatus includes means for focusing the emitted radiant energy into the reaction cell, and the reaction cell itself is preferably configured to reflect transmitted radiant energy back into the reaction medium to further improve the efficiency of the apparatus. The apparatus is well suited to the production of high-yield syntheses of 2-�.sup.18 F!fluoro-2-deoxy-D-glucose. Also provided is a method for performing organic synthetic reactions, including the manufacture of �.sup.18 F!-labeled compounds useful as PET radiotracers, and particularly for the preparation of 2-�.sup.18 F!fluoro-2-deoxy-D-glucose in higher yields than previously possible.
摘要翻译：用于进行有机合成反应的装置，特别是用于PET放射性示踪剂生产的无载体添加的亲核放射性氟化反应。该装置包括光学反应池和宽带红外辐射能源，其允许所发射的辐射能与反应介质直接耦合以加热反应介质。优选地，该装置包括用于将发射的辐射能聚焦到反应池中的装置，并且反应池本身优选地构造成将透射的辐射能量反射回反应介质中，以进一步提高装置的效率。该装置非常适用于生产2- [18 F]氟-2-脱氧-D-葡萄糖的高产率合成。还提供了用于进行有机合成反应的方法，包括制备可用作PET放射性示踪剂的[18 F]标记化合物，特别是制备2- [18 F]氟-2-脱氧-D-葡萄糖，产率高于以前可能的

2. 发明授权

US07286867B2 Combined PET/MRI scanner 有权
标题翻译：组合PET / MRI扫描仪
公开(公告)号：US07286867B2
公开(公告)日：2007-10-23
申请号：US10966412
申请日：2004-10-14
申请人： David Schlyer , Craig L. Woody , William Rooney , Paul Vaska , Sean Stoll , Jean-Francois Pratte , Paul O'Connor
发明人： David Schlyer , Craig L. Woody , William Rooney , Paul Vaska , Sean Stoll , Jean-Francois Pratte , Paul O'Connor
IPC分类号： A61B5/05
CPC分类号： G01T1/2985 , A61B5/0035 , A61B5/0042 , A61B5/055 , A61B6/037 , A61B6/4417 , A61B6/508 , A61B2503/40 , G01R33/481
摘要： A combined PET/MRI scanner generally includes a magnet for producing a magnetic field suitable for magnetic resonance imaging, a radiofrequency (RF) coil disposed within the magnetic field produced by the magnet and a ring tomograph disposed within the magnetic field produced by the magnet. The ring tomograph includes a scintillator layer for outputting at least one photon in response to an annihilation event, a detection array coupled to the scintillator layer for detecting the at least one photon outputted by the scintillator layer and for outputting a detection signal in response to the detected photon and a front-end electronic array coupled to the detection array for receiving the detection signal, wherein the front-end array has a preamplifier and a shaper network for conditioning the detection signal.
摘要翻译：组合的PET / MRI扫描器通常包括用于产生适于磁共振成像的磁场的磁体，设置在由磁体产生的磁场内的射频（RF）线圈和设置在由磁体产生的磁场内的环形断层摄影机。环形断层摄影机包括：闪烁体层，用于响应于湮灭事件输出至少一个光子;耦合到闪烁体层的检测阵列，用于检测由闪烁体层输出的至少一个光子，并响应于该闪烁体层输出检测信号检测到的光子和耦合到检测阵列的前端电子阵列用于接收检测信号，其中前端阵列具有用于调节检测信号的前置放大器和成形器网络。

3. 发明申请

US20050082486A1 Compact conscious animal positron emission tomography scanner 有权
标题翻译：紧凑型动物正电子发射断层扫描仪
公开(公告)号：US20050082486A1
公开(公告)日：2005-04-21
申请号：US10687797
申请日：2003-10-16
申请人： David Schlyer , Paul O'Connor , Craig Woody , Sachin Junnarkar , Veljko Radeka , Paul Vaska , Jean-Francois Pratte , Nora Volkow
发明人： David Schlyer , Paul O'Connor , Craig Woody , Sachin Junnarkar , Veljko Radeka , Paul Vaska , Jean-Francois Pratte , Nora Volkow
IPC分类号： A61B5/05 , G01T1/20 , G01T1/29
CPC分类号： A61B6/508 , A61B6/037 , A61B6/4417 , G01R33/481 , G01T1/2985
摘要： A method of serially transferring annihilation information in a compact positron emission tomography (PET) scanner includes generating a time signal for an event, generating an address signal representing a detecting channel, generating a detector channel signal including the time and address signals, and generating a composite signal including the channel signal and similarly generated signals. The composite signal includes events from detectors in a block and is serially output. An apparatus that serially transfers annihilation information from a block includes time signal generators for detectors in a block and an address and channel signal generator. The PET scanner includes a ring tomograph that mounts onto a portion of an animal, which includes opposing block pairs. Each of the blocks in a block pair includes a scintillator layer, detection array, front-end array, and a serial encoder. The serial encoder includes time signal generators and an address signal and channel signal generator.
摘要翻译：在紧凑型正电子发射断层摄影（PET）扫描仪中串行传送湮灭信息的方法包括产生事件的时间信号，产生表示检测通道的地址信号，产生包括时间和地址信号的检测器通道信号，复合信号包括信道信号和类似产生的信号。复合信号包括来自块中检测器的事件并且被串行输出。从块中串行地传送湮灭信息的装置包括用于块中的检测器的时间信号发生器，以及地址和通道信号发生器。 PET扫描仪包括环形断层摄影机，其安装在动物的包括相对的块对的部分上。块对中的每个块包括闪烁体层，检测阵列，前端阵列和串行编码器。串行编码器包括时间信号发生器和地址信号和通道信号发生器。

4. 发明申请

US20050167599A1 POSITRON EMISSION TOMOGRAPHY WRIST DETECTOR 有权
标题翻译： POSITRON排放测量手写检测器
公开(公告)号：US20050167599A1
公开(公告)日：2005-08-04
申请号：US10688577
申请日：2003-10-16
申请人： David Schlyer , Paul O'Connor , Craig Woody , Sachin Junnarkar , Veljko Radeka , Paul Vaska , Jean-Francois Pratte
发明人： David Schlyer , Paul O'Connor , Craig Woody , Sachin Junnarkar , Veljko Radeka , Paul Vaska , Jean-Francois Pratte
IPC分类号： G01T1/164 , G01T1/29
CPC分类号： G01T1/2985 , A61B6/037
摘要： A method of serially transferring annihilation information in a compact positron emission tomography (PET) scanner includes generating a time signal representing a time-of-occurrence of an annihilation event, generating an address signal representing a channel detecting the annihilation event, and generating a channel signal including the time and address signals. The method also includes generating a composite signal including the channel signal and another similarly generated channel signal concerning another annihilation event. An apparatus that serially transfers annihilation information includes a time signal generator, address signal generator, channel signal generator, and composite signal generator. The time signal is asynchronous and the address signal is synchronous to a clock signal. A PET scanner includes a scintillation array, detection array, front-end array, and a serial encoder. The serial encoders include the time signal generator, address signal generator, channel signal generator, and composite signal generator.
摘要翻译：在紧凑型正电子发射断层摄影（PET）扫描仪中串行传送湮灭信息的方法包括产生表示湮灭事件发生时间的时间信号，产生表示检测湮灭事件的信道的地址信号，以及生成信道信号包括时间和地址信号。该方法还包括生成包括信道信号的复合信号和关于另一个湮灭事件的另一类似的生成的信道信号。串行传送湮灭信息的装置包括时间信号发生器，地址信号发生器，信道信号发生器和复合信号发生器。时间信号是异步的，地址信号与时钟信号同步。 PET扫描仪包括闪烁阵列，检测阵列，前端阵列和串行编码器。串行编码器包括时间信号发生器，地址信号发生器，信道信号发生器和复合信号发生器。

5. 发明申请

US20050113667A1 Combined PET/MRI scanner 有权
标题翻译：组合PET / MRI扫描仪
公开(公告)号：US20050113667A1
公开(公告)日：2005-05-26
申请号：US10966412
申请日：2004-10-14
申请人： David Schlyer , Craig Woody , William Rooney , Paul Vaska , Sean Stoll , Jean-Francois Pratte , Paul O'Connor
发明人： David Schlyer , Craig Woody , William Rooney , Paul Vaska , Sean Stoll , Jean-Francois Pratte , Paul O'Connor
IPC分类号： A61B5/05 , G01T1/20 , G01T1/29
CPC分类号： G01T1/2985 , A61B5/0035 , A61B5/0042 , A61B5/055 , A61B6/037 , A61B6/4417 , A61B6/508 , A61B2503/40 , G01R33/481
摘要： A combined PET/MRI scanner generally includes a magnet for producing a magnetic field suitable for magnetic resonance imaging, a radiofrequency (RF) coil disposed within the magnetic field produced by the magnet and a ring tomograph disposed within the magnetic field produced by the magnet. The ring tomograph includes a scintillator layer for outputting at least one photon in response to an annihilation event, a detection array coupled to the scintillator layer for detecting the at least one photon outputted by the scintillator layer and for outputting a detection signal in response to the detected photon and a front-end electronic array coupled to the detection array for receiving the detection signal, wherein the front-end array has a preamplifier and a shaper network for conditioning the detection signal.
摘要翻译：组合的PET / MRI扫描器通常包括用于产生适于磁共振成像的磁场的磁体，设置在由磁体产生的磁场内的射频（RF）线圈和设置在由磁体产生的磁场内的环形断层摄影机。环形断层摄影机包括：闪烁体层，用于响应于湮灭事件输出至少一个光子;耦合到闪烁体层的检测阵列，用于检测由闪烁体层输出的至少一个光子，并响应于该闪烁体层输出检测信号检测到的光子和耦合到检测阵列的前端电子阵列用于接收检测信号，其中前端阵列具有用于调节检测信号的前置放大器和成形器网络。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式