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1. 发明授权

US06670167B1 Catalytic domain of the human effector cell cycle checkpoint protein kinase materials and methods for identification of inhibitors thereof 失效
标题翻译：人效应细胞周期检查点蛋白激酶材料的催化结构域及其抑制剂的鉴定方法
公开(公告)号：US06670167B1
公开(公告)日：2003-12-30
申请号：US09460421
申请日：1999-12-14
申请人： Ping Chen , Mark Anderson , Ya-Li Deng , Smita Gaur , Chen Chen Kan , Chun Luo , Karen Lundgren , Stephen Margosiak , Binh Nguyen , Patrick O'Connor , James Register , Anna Tempczyk Russell , Jay Sarup
发明人： Ping Chen , Mark Anderson , Ya-Li Deng , Smita Gaur , Chen Chen Kan , Chun Luo , Karen Lundgren , Stephen Margosiak , Binh Nguyen , Patrick O'Connor , James Register , Anna Tempczyk Russell , Jay Sarup
IPC分类号： C07H2104
CPC分类号： C12N9/1205 , C12Q1/34
摘要： The present invention relates to the identification, isolation and purification of the catalytic domain of the human effector checkpoint protein kinase (hChk1). A 1.7Å crystal structure of the hChk1 kinase domain in the active conformation is reported herein. The kinase domain of hChk1 and its associated crystal structure is described for use in the discovery, identification and characterization of inhibitors of hChk1. This structure provides a three-dimensional description of the binding site of the hChk1 for structure-based design of small molecule inhibitors thereof as therapeutic agents. Inhibitors of hChk1 find utility in the treatment of hyperproliferative disorders such as HIV and cancer.
摘要翻译：本发明涉及人类效应子检测点蛋白激酶（hChk1）的催化结构域的鉴定，分离和纯化。本文报道了活性构象中hChk1激酶结构域的1.7Å晶体结构。描述了hChk1的激酶结构域及其相关晶体结构，用于hChk1抑制剂的发现，鉴定和表征。该结构提供了hChk1的结合位点的三维描述，用于其作为治疗剂的小分子抑制剂的基于结构的设计。 hChk1的抑制剂可用于治疗过度增生性疾病如艾滋病毒和癌症。

2. 发明授权

US10762744B2 Automated money laundering detection, notification, and reporting techniques implemented at casino gaming networks 有权
公开(公告)号：US10762744B2
公开(公告)日：2020-09-01
申请号：US15644608
申请日：2017-07-07
申请人： FRESH IDEA GLOBAL LIMITED , Binh Nguyen
发明人： Jay Chun , Binh Nguyen
IPC分类号： G06F17/00 , G07F17/32 , G06Q20/10 , G07G3/00 , G06Q20/40
摘要： Various aspects described or referenced herein are directed to different methods, systems, and computer program products for implementing automated money laundering detection, notification, and reporting techniques implemented at casino gaming networks.

3. 发明授权

US10227695B2 Shadow ring for modifying wafer edge and bevel deposition 有权
公开(公告)号：US10227695B2
公开(公告)日：2019-03-12
申请号：US12974365
申请日：2010-12-21
申请人： Dale R. Du Bois , Mohamad A. Ayoub , Robert Kim , Amit Bansal , Mark Fodor , Binh Nguyen , Siu F. Cheng , Hang Yu , Chiu Chan , Ganesh Balasubramanian , Deenesh Padhi , Juan Carlos Rocha
发明人： Dale R. Du Bois , Mohamad A. Ayoub , Robert Kim , Amit Bansal , Mark Fodor , Binh Nguyen , Siu F. Cheng , Hang Yu , Chiu Chan , Ganesh Balasubramanian , Deenesh Padhi , Juan Carlos Rocha
IPC分类号： C23C14/04 , C23C16/04 , C23C16/44 , C23C16/455 , C23C16/458 , C30B25/12 , H01J37/32 , H01J37/34 , H01L21/687
摘要： Embodiments of the invention contemplate a shadow ring that provides increased or decreased and more uniform deposition on the edge of a wafer. By removing material from the top and/or bottom surfaces of the shadow ring, increased edge deposition and bevel coverage can be realized. In one embodiment, the material on the bottom surface is reduced by providing a recessed slot on the bottom surface. By increasing the amount of material of the shadow ring, the edge deposition and bevel coverage is reduced. Another approach to adjusting the deposition at the edge of the wafer includes increasing or decreasing the inner diameter of the shadow ring. The material forming the shadow ring may also be varied to change the amount of deposition at the edge of the wafer.

4. 发明申请

US20170309121A1 AUTOMATED MONEY LAUNDERING DETECTION, NOTIFICATION, AND REPORTING TECHNIQUES IMPLEMENTED AT CASINO GAMING NETWORKS 审中-公开
公开(公告)号：US20170309121A1
公开(公告)日：2017-10-26
申请号：US15644608
申请日：2017-07-07
申请人： BINH NGUYEN , FRESH IDEA GLOBAL LIMITED
发明人： Jay Chun , Binh Nguyen
IPC分类号： G07F17/32 , G06Q20/40 , G07G3/00 , G06Q20/10
摘要： Various aspects described or referenced herein are directed to different methods, systems, and computer program products for implementing automated money laundering detection, notification, and reporting techniques implemented at casino gaming networks.

5. 发明授权

US09724729B2 Method of modifying a coating on a medical device 有权
公开(公告)号：US09724729B2
公开(公告)日：2017-08-08
申请号：US12976279
申请日：2010-12-22
申请人： Victoria M. Gong , John Stankus , Stephen D. Pacetti , Anthony S. Andreacchi , Benny Serna , Binh Nguyen
发明人： Victoria M. Gong , John Stankus , Stephen D. Pacetti , Anthony S. Andreacchi , Benny Serna , Binh Nguyen
IPC分类号： B05D3/00 , A61F2/82 , B05D3/10 , A61L27/34 , A61L27/50
CPC分类号： B05D3/107 , A61L27/34 , A61L27/50 , A61L2400/18
摘要： Method of modifying the coating of a surface of a medical device by applying a coating to the surface of the medical device, exposing the medical device to an environmental condition that alters the coating morphology, and drying the coating on the medical device. The disclosed subject matter also provides a coated medical device whose one or more surfaces have been modified by this method.

6. 发明授权

US08940358B2 Maintaining a fixed distance by laser or sonar assisted positioning during coating of a medical device 有权
标题翻译：通过激光或声纳保持固定距离辅助定位医疗器械的涂层
公开(公告)号：US08940358B2
公开(公告)日：2015-01-27
申请号：US13158057
申请日：2011-06-10
申请人： Binh Nguyen , Randy Shen
发明人： Binh Nguyen , Randy Shen
IPC分类号： A61M25/00 , A61M25/10 , B05B13/04 , B05C5/00
CPC分类号： A61M25/1029 , A61M2025/1031 , A61M2025/105 , B05B13/0442 , B05C5/00
摘要： System and method for coating an expandable member of a medical device comprising a support structure to support the expandable member and an applicator positioned with at least one outlet proximate a surface of an expandable member. A drive assembly establishes relative movement between the at least one outlet and the surface of the expandable member to apply fluid on the surface of the expandable member along a coating path. A positioning device is provided to determine the distance to the surface of the expandable member at a corresponding location and relays the information to a controller or the like to maintain a substantially fixed distance between the outlet of the applicator and the surface of the expandable member when in alignment with the corresponding location.
摘要翻译：用于涂覆医疗装置的可膨胀构件的系统和方法，包括支撑结构以支撑可膨胀构件，以及施加器，其定位成邻近可扩张构件的表面的至少一个出口。驱动组件在至少一个出口和可膨胀构件的表面之间建立相对运动，以沿着涂覆路径向可扩张构件的表面施加流体。提供定位装置以确定在相应位置处到可扩张构件的表面的距离，并将信息中继到控制器等，以在施用器的出口和可扩张构件的表面之间保持基本上固定的距离，与对应的位置对齐。

7. 发明申请

US20120315376A1 Method And System To Maintain A Fixed Distance During Coating Of A Medical Device 有权
标题翻译：医疗器械涂层中保持固定距离的方法和系统
公开(公告)号：US20120315376A1
公开(公告)日：2012-12-13
申请号：US13158131
申请日：2011-06-10
申请人： Binh Nguyen , Benjamyn Serna , Stephen D. Pacetti , Victoria M. Gong
发明人： Binh Nguyen , Benjamyn Serna , Stephen D. Pacetti , Victoria M. Gong
IPC分类号： A61M25/10 , B05C5/02
CPC分类号： A61M25/1029 , A61M2025/1031 , A61M2025/105 , B05B13/0442 , B05C5/02
摘要： Method and system to coat an expandable member of a medical device comprising a support structure to support the expandable member and an applicator positioned with at least one outlet proximate a surface of an expandable member. A drive assembly establishes relative movement between the at least one outlet and the surface of the expandable member to apply fluid on the surface of the expandable member along a coating path. A tracking mechanism maintains a substantially fixed distance between the at least one outlet and the surface of the expandable member during relative movement therebetween by displacing the at least one outlet relative to the expandable member.
摘要翻译：涂覆医疗装置的可扩张构件的方法和系统，包括支撑结构以支撑可膨胀构件以及位于靠近可扩张构件的表面的至少一个出口的施用器。驱动组件在至少一个出口和可膨胀构件的表面之间建立相对运动，以沿着涂覆路径向可扩张构件的表面施加流体。跟踪机构通过相对于可扩展构件移位至少一个出口而在相对移动期间在至少一个出口和可扩张构件的表面之间保持基本固定的距离。

8. 发明申请

US20120278797A1 METHODS AND SYSTEMS FOR PACKAGING ENCAPSULATED OPERATING SYSTEM AND CUSTOM SOFTWARE FOR SINGLE STREAM MULTI-SYSTEM INSTALLATION 审中-公开
标题翻译：用于包装封装操作系统的方法和系统以及用于单流多系统安装的自定义软件
公开(公告)号：US20120278797A1
公开(公告)日：2012-11-01
申请号：US13401340
申请日：2012-02-21
申请人： Randy Kent Secrist , Vijayanand Tirumalai , Binh Nguyen
发明人： Randy Kent Secrist , Vijayanand Tirumalai , Binh Nguyen
IPC分类号： G06F9/445
CPC分类号： G06F8/63 , G06F8/71
摘要： Certain examples provide a clinical information system software system. The example system includes a decomposer to decompose system functions included in a system concept into a plurality of individual functional components. The example system includes a design process to transform the plurality of functional components into a series of input files that include definitions to describe components forming a clinical information system configuration for installation. The example system includes a product generator to combine the information in the series of input files into a single software artifact including information and functionality to bootstrap and load a machine node and make the software artifact available to a target site for execution and installation.
摘要翻译：某些例子提供临床信息系统软件系统。该示例系统包括分解器以将包括在系统概念中的系统功能分解为多个单独的功能组件。该示例系统包括将多个功能组件变换成包括定义以描述形成用于安装的临床信息系统配置的组件的一系列输入文件的设计过程。示例系统包括产品生成器，用于将一系列输入文件中的信息合并为单个软件工件，其中包括信息和功能，以引导和加载机器节点，并使软件工件可用于目标站点以进行执行和安装。

9. 发明授权

US08287380B2 Intelligent wireless mobile device for use with casino gaming table systems 有权
标题翻译：用于赌场游戏桌系统的智能无线移动设备
公开(公告)号：US08287380B2
公开(公告)日：2012-10-16
申请号：US11515183
申请日：2006-09-01
申请人： Binh Nguyen , Kevin Gum , Chauncey Griswold
发明人： Binh Nguyen , Kevin Gum , Chauncey Griswold
IPC分类号： A63F9/24 , A63F13/00 , G06F17/00 , G06F19/00
CPC分类号： G07F17/32 , G07F17/3218 , G07F17/3223 , G07F17/3293
摘要： A technique is disclosed for facilitating play of a casino table game at a casino gaming table system which includes a casino gaming table and at least one handheld device. At least a portion of operations or activities relating to the casino game may be performed at a first handheld device. Examples of such operations may include electronically dealing a first card to a first player via the first handheld device, displaying a representation of the first card to the first player via a display at the first handheld device, etc. In at least one embodiment, an association between a selected handheld device and the first player station may be created and used for subsequent game play activities to enable the selected handheld device to be operable to display game play data relating to game play activities associated with the first player station. In some embodiments, at least a portion of the features of a selected handheld device may be enabled/disabled based on the detection of one or more conditions or events. According to specific embodiments, the handheld device may be adapted to provide various functionality for facilitating game play at a casino gaming table. Examples of such functionality may include, for example, allowing a player to select cards for discard/holding; allowing a player to perform wagering activities; retrieving and/or displaying player tracking data; retrieving and/or displaying player account data; displaying game play assistance information; displaying casino layout information; displaying promotional information; etc.
摘要翻译：公开了一种用于促进在娱乐场游戏桌系统中的娱乐场桌面游戏的播放的技术，其包括娱乐场游戏桌和至少一个手持设备。与赌场游戏相关的操作或活动的至少一部分可以在第一手持设备上执行。这种操作的示例可以包括经由第一手持设备将第一卡片电子交易给第一播放器，经由第一手持设备上的显示器将第一卡片的表示显示给第一播放器等。在至少一个实施例中，可以创建所选择的手持设备和第一播放器站之间的关联并用于随后的游戏活动，以使所选择的手持设备可操作以显示与与第一玩家站相关联的游戏活动相关的游戏数据。在一些实施例中，可以基于对一个或多个条件或事件的检测来启用/禁用所选手持设备的特征的至少一部分。根据具体实施例，手持设备可以适于提供用于促进游戏机游戏桌面的游戏的各种功能。这种功能的示例可以包括例如允许玩家选择用于丢弃/保持的卡; 允许玩家进行投注活动; 检索和/或显示玩家跟踪数据; 检索和/或显示玩家帐户数据; 显示游戏辅助信息; 展示赌场布局信息; 展示宣传资料; 等等

10. 发明授权

US08133113B2 Class II/Class III hybrid gaming machine, system and methods 有权
标题翻译： II类/ III类混合游戏机，系统和方法
公开(公告)号：US08133113B2
公开(公告)日：2012-03-13
申请号：US10995636
申请日：2004-11-22
申请人： Binh Nguyen , James Stockdale , Bryan Wolf
发明人： Binh Nguyen , James Stockdale , Bryan Wolf
IPC分类号： A63F13/00
CPC分类号： G07F17/3225 , G07F17/32 , G07F17/3232 , G07F17/3262
摘要： The present invention provides a gaming machine that can play both Class II and Class III games. Some implementations provide a gaming machine that has certain features (e.g., a true random number generator or “RNG”) enabled for Class III play and disabled for Class II play. Some aspects of the invention provide methods for determining when a Class III game is available. Other aspects of the invention allow a player to “line up” for a desired Class III game while playing another game, such as a Class II game or another Class III game, on the same gaming machine until the desired Class III game is available. Some such implementations grant higher priority to certain players according to their gaming history, e.g., as indicated by player tracking/player loyalty data. Alternative aspects of the invention allocate available Class III games in other ways, e.g., by playing a Class II game for a chance to play a Class III game, by lottery, or otherwise. Player tracking information may be shared and/or combined for Class II and Class III game play and may be used to determine gaming history.
摘要翻译：本发明提供一种可以玩II类和III类游戏的游戏机。一些实施方案提供具有为III类播放启用并且对于II类播放禁用的某些特征（例如，真随机数生成器或“RNG”）的游戏机。本发明的一些方面提供了用于确定何时可以使用III类游戏的方法。本发明的其他方面允许玩家在同一游戏机上玩另一游戏（例如II类游戏或另一类III类游戏）时，对所需的III类游戏“排队”，直到所需的III类游戏可用。一些这样的实现根据其游戏历史给予某些玩家更高的优先级，例如，如玩家跟踪/玩家忠诚度数据所示。本发明的替代方面以其他方式分配可用的III类游戏，例如通过玩II类游戏机会玩彩票或其他类型的III类游戏。玩家跟踪信息可以共享和/或组合用于II类和III类游戏，并可用于确定游戏历史。

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