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1. 发明授权

US07795868B2 Hyperpolarized dynamic chemical shift imaging with tailored multiband excitation pulses 有权
标题翻译：超极化动态化学位移成像与定制的多频激励脉冲
公开(公告)号：US07795868B2
公开(公告)日：2010-09-14
申请号：US12247940
申请日：2008-10-08
申请人： Peder E. Larson , John M. Pauly , Daniel B. Vigneron , Albert Chen , Adam B. Kerr
发明人： Peder E. Larson , John M. Pauly , Daniel B. Vigneron , Albert Chen , Adam B. Kerr
IPC分类号： G01V3/00
CPC分类号： G01R33/485
摘要： A method for performing magnetic resonance spectroscopy is described. The method generally includes applying a tailored multiband spectral-spatial radio frequency excitation pulse to a sample including a first species and at least a second species having a different resonant frequency than the first species. The multiband excitation pulse excites the first species according to a first amplitude and excites the second species according to a second amplitude that is substantially greater than the first amplitude. Data is acquired from the sample. The acquired data is then utilized to generate a spectroscopic output. By way of example, the spectroscopic output is a spectroscopic image. In particular embodiments, the data for the first and second species is acquired dynamically over an observation window of time.
摘要翻译：描述用于执行磁共振光谱的方法。该方法通常包括将定制的多频谱 - 空间射频激励脉冲应用于包括具有与第一种类不同的共振频率的第一物种和至少第二种类的样品。所述多频带激励脉冲根据第一幅度激发所述第一种类，并且根据明显大于所述第一幅度的第二幅度激发所述第二种类。从样品中获取数据。然后利用获取的数据产生光谱输出。作为示例，分光输出是分光图像。在特定实施例中，在观察窗口上动态地获取第一和第二物种的数据。

2. 发明申请

US20100085046A1 HYPERPOLARIZED DYNAMIC CHEMICAL SHIFT IMAGING WITH TAILORED MULTIBAND EXCITATION PULSES 有权
标题翻译：具有多功能激光脉冲激光的高效动态化学转换成像
公开(公告)号：US20100085046A1
公开(公告)日：2010-04-08
申请号：US12247940
申请日：2008-10-08
申请人： Peder E. Larson , John M. Pauly , Daniel B. Vigneron , Albert Chen , Adam B. Kerr
发明人： Peder E. Larson , John M. Pauly , Daniel B. Vigneron , Albert Chen , Adam B. Kerr
IPC分类号： G01R33/46
CPC分类号： G01R33/485
摘要： A method for performing magnetic resonance spectroscopy is described. The method generally includes applying a tailored multiband spectral-spatial radio frequency excitation pulse to a sample including a first species and at least a second species having a different resonant frequency than the first species. The multiband excitation pulse excites the first species according to a first amplitude and excites the second species according to a second amplitude that is substantially greater than the first amplitude. Data is acquired from the sample. The acquired data is then utilized to generate a spectroscopic output. By way of example, the spectroscopic output is a spectroscopic image. In particular embodiments, the data for the first and second species is acquired dynamically over an observation window of time.
摘要翻译：描述用于执行磁共振光谱的方法。该方法通常包括将定制的多频谱 - 空间射频激励脉冲应用于包括具有与第一种类不同的共振频率的第一物种和至少第二种类的样品。所述多频带激励脉冲根据第一幅度激发所述第一种类，并且根据明显大于所述第一幅度的第二幅度激发所述第二种类。从样品中获取数据。然后利用获取的数据产生光谱输出。作为示例，分光输出是分光图像。在特定实施例中，在观察窗口上动态地获取第一和第二物种的数据。

3. 发明授权

US09170312B2 Phase-sensitive imaging of magnetization exchange and isotope flux 有权
标题翻译：磁化交换和同位素通量的相敏成像
公开(公告)号：US09170312B2
公开(公告)日：2015-10-27
申请号：US13360510
申请日：2012-01-27
申请人： Peder Larson , Adam B. Kerr , John M. Pauly , Daniel B. Vigneron
发明人： Peder Larson , Adam B. Kerr , John M. Pauly , Daniel B. Vigneron
IPC分类号： G01V3/00 , G01R33/46 , G01R33/563 , G01R33/485 , G01R33/56
CPC分类号： G01R33/4608 , G01R33/4616 , G01R33/485 , G01R33/5601 , G01R33/5605 , G01R33/56333
摘要： A method for imaging a substrate and product over time is provided. The substrate and product are magnetically tagged with at least one magnetic gradient where magnetically tagging provides a tag-dependent signal phase for the substrate and a different tag-dependent signal phase for the product. At least one readout of magnetically tagged substrate and product is provided over time. The tag-dependent signal phase is used to determine product that has been transformed from magnetically tagged substrate and substrate that has been transformed from magnetically tagged product over time.
摘要翻译：提供了一种用于对衬底和产品随时间成像的方法。衬底和产品用至少一个磁梯度进行磁性标记，其中磁性标签为衬底提供与标签相关的信号相位，并为产品提供不同的标签依赖信号相位。随着时间的推移，提供至少一个磁性标记的基板和产品读数。标签依赖信号相位用于确定已经从磁标记的产品随时间变换的磁性标记的基底和底物转变的产物。

4. 发明授权

US5905377A Method and apparatus for correcting gradient system and static magnetic field in magnetic resonance imaging 失效
标题翻译：用于校正磁共振成像中梯度系统和静磁场的方法和装置
公开(公告)号：US5905377A
公开(公告)日：1999-05-18
申请号：US690528
申请日：1996-07-31
申请人： Adam B. Kerr , John M. Pauly
发明人： Adam B. Kerr , John M. Pauly
IPC分类号： G01R33/389 , G01R33/565 , G01V3/00
CPC分类号： G01R33/389 , G01R33/56518 , G01R33/56563
摘要： Time-varying error between a prescribed magnetic field and an actual magnetic field is identified from a self-encoding technique and the measurement of detected responses to various magnetic read-out gradients. The gradients can be a sinusoidal, step function, or other suitable form which enables the actual responses to be obtained from which transfer functions can be defined. In one embodiment, the data can effectively frequency sample the transfer function of the system. A gradient-recalled echo occurs each time the self-encode lobe is refocussed, and the phase of the echo peak is used to estimate the time variation of the main magnetic field, B.sub.0 (t).
摘要翻译：从自编码技术和对各种磁读出梯度的检测到的响应的测量来识别规定磁场和实际磁场之间的时变误差。梯度可以是正弦，阶梯函数或其他合适的形式，其使得能够从可以定义传递函数获得实际响应。在一个实施例中，数据可以有效地对系统的传递函数进行频率采样。每次自编码波瓣重新聚焦时都会发生梯度回波，回波峰值的相位用于估计主磁场B0（t）的时间变化。

5. 发明授权

US5856744A Method and apparatus for B.sub.0 eddy current compensation by B.sub.1 phase modulation 失效
标题翻译：通过B1相位调制进行B0涡流补偿的方法和装置
公开(公告)号：US5856744A
公开(公告)日：1999-01-05
申请号：US772684
申请日：1996-12-23
申请人： Walter F. Block , Adam B. Kerr , John M. Pauly
发明人： Walter F. Block , Adam B. Kerr , John M. Pauly
IPC分类号： G01R33/565 , G01V3/00
CPC分类号： G01R33/56518
摘要： In accordance with the invention, spatially invariant B.sub.0 eddy currents induced by a slice-selection gradient, G.sub.Z in an MRI system, are compensated by phase modulating the RF excitation pulse with a compensating function. In one embodiment, the compensating function is based on a measure of the integral of the B.sub.0 eddy current. In another embodiment, a scaled copy of the excitation gradient can be used as an approximation of the compensating function.
摘要翻译：根据本发明，通过利用补偿功能对RF激励脉冲进行相位调制来补偿由MRI系统中的切片选择梯度GZ引起的空间不变的B0涡流。在一个实施例中，补偿功能基于B0涡流的积分的度量。在另一个实施例中，可以使用激励梯度的缩放副本作为补偿功能的近似。

6. 发明授权

US5499629A Slice profile stabilization for segmented k-space magnetic resonance imaging 失效
标题翻译：用于分段k空间磁共振成像的切片轮廓稳定
公开(公告)号：US5499629A
公开(公告)日：1996-03-19
申请号：US191342
申请日：1994-02-01
申请人： Adam B. Kerr , John M. Pauly
发明人： Adam B. Kerr , John M. Pauly
IPC分类号： G01R33/48 , G01R33/58 , A61B5/055
CPC分类号： G01R33/446 , G01R33/586
摘要： Selective RF pulses are applied for segmented k-space imaging sequences with the tip-angle profiles of the pulses varying for stabilizing the entire signal profile and reducing ghosting and blurring artifacts in slice images.
摘要翻译：选择性RF脉冲被应用于分段的k空间成像序列，其中脉冲的尖角分布变化以稳定整个信号分布并减少切片图像中的重影和模糊伪像。

7. 发明授权

US07593693B1 Adaptive antenna array with programmable sensitivity 失效
标题翻译：具有可编程灵敏度的自适应天线阵列
公开(公告)号：US07593693B1
公开(公告)日：2009-09-22
申请号：US11375500
申请日：2006-03-13
申请人： Athanasios A. Kasapi , Mitchell D. Trott , Peter G. Khoury , Adam B. Kerr , Serge Barbosa Da Torre
发明人： Athanasios A. Kasapi , Mitchell D. Trott , Peter G. Khoury , Adam B. Kerr , Serge Barbosa Da Torre
IPC分类号： H04B17/00 , H04B1/00 , H04B15/00
CPC分类号： H04B7/0854
摘要： Methods and apparatus for calculating spatial processing strategies in adaptive antenna array processing systems. Reference signal quality, intersymbol interference, data processed and received signal quality can be determined by burst type or remote device type and used to determine a synthetic signal level for use in developing a spatial processing strategy. A synthetic signal have an isotropically distributed component can be added to the antennas in the array or the diagonal elements of the received signal covariance matrix to develop uplink and downlink spatial processing strategies. Different synthetic signals at different signal levels can be used to develop different uplink and downlink spatial processing strategies. The downlink signal level can be larger than the uplink signal level. Uplink and downlink processing strategies can be developed in substantially the same way.
摘要翻译：自适应天线阵列处理系统中空间处理策略的计算方法与装置。参考信号质量，码间干扰，数据处理和接收信号质量可以通过突发类型或远程设备类型确定，并用于确定用于开发空间处理策略的合成信号电平。合成信号具有各向同性分布的分量可以添加到阵列中的天线或接收信号协方差矩阵的对角元素，以开发上行链路和下行链路空间处理策略。不同信号级别的不同合成信号可用于开发不同的上行链路和下行链路空间处理策略。下行链路信号电平可以大于上行链路信号电平。上行链路和下行链路处理策略可以以相同的方式开发。

8. 发明授权

US06570527B1 Calibration of differential frequency-dependent characteristics of a radio communications system 有权
标题翻译：校准无线电通信系统的差分频率相关特性
公开(公告)号：US06570527B1
公开(公告)日：2003-05-27
申请号：US09967258
申请日：2001-09-28
申请人： Erik D. Lindskog , Mitchell D. Trott , Adam B. Kerr
发明人： Erik D. Lindskog , Mitchell D. Trott , Adam B. Kerr
IPC分类号： G01S740
CPC分类号： H04B7/12 , H01Q3/267 , H04B7/0613 , H04B7/0837 , H04B17/12 , H04B17/21
摘要： A method and apparatus are provided that determine a frequency dependent calibration vector for a set of transmit or receive chains of a radio communications system using only differential phase and amplitude between the transmit chains and the receive chains, respectively. In one embodiment, the invention includes an antenna array adapted to transmit and receive radio communications signals with a plurality of other terminals, a transmit chain to transmit a calibration signal through the antenna array to a transponder on at least two different frequency bands, and a receive chain to receive through the antenna array a transponder signal from the transponder, the transponder signal being received on at least two different frequency bands and being based on the calibration signal. A signal processor determines a frequency dependent calibration vector based on the at least two frequency bands of the transponder signal as received through the receive chain by comparing relative characteristics for the transponder signal at a first one of the at least two frequencies to relative characteristics for the transponder signal at a second one of the at least two frequencies.
摘要翻译：提供了一种方法和装置，其分别仅使用发射链和接收链之间的差分相位和幅度来确定无线电通信系统的一组发射或接收链的频率相关校准矢量。在一个实施例中，本发明包括适于与多个其他终端发送和接收无线电通信信号的天线阵列，通过天线阵列将校准信号发射到至少两个不同频带上的应答器的发射链，以及接收链，以通过天线阵列接收来自应答器的应答器信号，应答器信号在至少两个不同频带上被接收并且基于校准信号。信号处理器基于通过接收链接收的应答器信号的至少两个频带来确定与频率相关的校准矢量，通过将在至少两个频率中的第一个频率上的应答器信号的相对特性相对于在所述至少两个频率中的第二个频率处的应答器信号。

9. 发明授权

US07039363B1 Adaptive antenna array with programmable sensitivity 有权
公开(公告)号：US07039363B1
公开(公告)日：2006-05-02
申请号：US09967896
申请日：2001-09-28
申请人： Athanasios A. Kasapi , Mitchell D. Trott , Peter G. Khoury , Adam B. Kerr , Serge Barbosa Da Torre
发明人： Athanasios A. Kasapi , Mitchell D. Trott , Peter G. Khoury , Adam B. Kerr , Serge Barbosa Da Torre
IPC分类号： H04B17/00 , H04B7/212 , H04J3/12
CPC分类号： H04B7/0854
摘要： Methods and apparatus for calculating spatial processing strategies in adaptive antenna array processing systems. Reference signal quality, intersymbol interference, data processed and received signal quality can be determined by burst type or remote device type and used to determine a synthetic signal level for use in developing a spatial processing strategy. A synthetic signal have an isotropically distributed component can be added to the antennas in the array or the diagonal elements of the received signal covariance matrix to develop uplink and downlink spatial processing strategies. Different synthetic signals at different signal levels can be used to develop different uplink and downlink spatial processing strategies. The downlink signal level can be larger than the uplink signal level. Uplink and downlink processing strategies can be developed in substantially the same way.

10. 发明授权

US07342912B1 Selection of user-specific transmission parameters for optimization of transmit performance in wireless communications using a common pilot channel 有权
标题翻译：选择用户特定的传输参数，以优化使用公共导频信道的无线通信中的传输性能
公开(公告)号：US07342912B1
公开(公告)日：2008-03-11
申请号：US10187026
申请日：2002-06-28
申请人： Adam B. Kerr , Erik D. Lindskog , Christopher Brunner , Mitchell D. Trott
发明人： Adam B. Kerr , Erik D. Lindskog , Christopher Brunner , Mitchell D. Trott
IPC分类号： H04B7/212 , H04B1/76
CPC分类号： H04B7/0615 , H04L25/0224
摘要： A method and apparatus are provided that optimizes a transmitted user-specific signal. In one embodiment, the invention includes receiving signals from a remote radio, deriving estimates of receive channels corresponding to the received signals using the received signals, deriving a model of an expected transmit channel to the remote radio based on the receive channel estimates, deriving a set of transmit parameters to be applied to an array of transmit antennas to transmit a signal to the remote radio by optimizing a transmit power criteria using the model of the expected transmit channel and constraints on the estimated quality of a signal transmitted over the expected transmit channel, and transmitting to the remote radio by applying the derived set of transmit parameters to the transmit antenna array.
摘要翻译：提供了一种优化发送的用户特定信号的方法和装置。在一个实施例中，本发明包括从远程无线电接收信号，使用接收到的信号导出对应于接收信号的接收信道的估计，基于接收信道估计导出到远程无线电的期望发射信道的模型，导出通过使用预期发射信道的模型优化发射功率标准并对通过预期发射信道传输的信号的估计质量的约束来将应用于发射天线阵列的发射参数集合发射到远程无线电信号。并且通过将衍生的发射参数集合应用于发射天线阵列来发射到远程无线电装置。

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