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1. 发明授权

US09533245B2 Filter device and analysis device using same 有权
标题翻译：过滤装置和分析装置使用相同
公开(公告)号：US09533245B2
公开(公告)日：2017-01-03
申请号：US14258892
申请日：2014-04-22
申请人： PANASONIC CORPORATION
发明人： Masaya Nakatani , Hiroaki Oka , Daniel Yazbeck , Takeki Yamamoto , Takahiro Nogami
IPC分类号： B01D39/08 , G01N33/49 , D04H1/4218 , D04H1/4326 , D04H1/54 , B01J20/28 , B01J20/283 , B01J20/286 , B01J20/32 , B01J20/10 , G01N21/05 , G01N1/40 , B01L3/00 , B01D15/34 , G01N21/03
CPC分类号： B01D39/086 , B01D15/34 , B01J20/103 , B01J20/28038 , B01J20/283 , B01J20/286 , B01J20/3246 , B01J2220/54 , B01L3/502753 , B01L3/5635 , D04H1/4218 , D04H1/4326 , D04H1/54 , G01N21/05 , G01N33/491 , G01N2001/4088 , G01N2021/0325
摘要： A filter device of the present disclosure includes at least a sheet-shaped fiber structure having a plurality of fibers made of amorphous silicon dioxide, wherein the plurality of fibers are tangled and thus connected together to form voids in the sheet-shaped fiber structure. A filter device of the present disclosure corresponds to an analysis device including: a substrate; a flow path formed on the substrate; and a sheet-shaped fiber structure provided on the inner wall of the flow path, wherein the sheet-shaped fiber structure includes a plurality of fibers made of amorphous silicon dioxide, and the plurality of fibers are tangled and thus connected together to form voids in the sheet-shaped fiber structure.
摘要翻译：本公开的过滤器装置至少包括具有多个由无定形二氧化硅制成的纤维的片状纤维结构，其中多个纤维缠结并因此连接在一起以在片状纤维结构中形成空隙。本公开的过滤装置对应于分析装置，包括：基板; 形成在所述基板上的流路; 以及设置在所述流路的内壁上的片状纤维结构体，其中，所述片状纤维结构体包括多个由无定形二氧化硅制成的纤维，所述多根纤维缠结并因此连接在一起形成空隙片状纤维结构。

2. 发明授权

US09184048B2 Method of manufacturing cellular electrophysiology sensor chip 有权
标题翻译：细胞生物传感器芯片制造方法
公开(公告)号：US09184048B2
公开(公告)日：2015-11-10
申请号：US13713065
申请日：2012-12-13
申请人： Panasonic Corporation
发明人： Makoto Takahashi , Masaya Nakatani , Hiroshi Ushio , Takeki Yamamoto
IPC分类号： H01L21/02 , G01N33/487
CPC分类号： H01L21/02356 , G01N33/48728
摘要： A cellular electrophysiology sensor is adapted to measure an electrical change of a test cell. A chip for the sensor includes a diaphragm, and a thermally-oxidized film mainly containing silicon dioxide on the diaphragm. The diaphragm includes a silicon layer and a silicon dioxide layer on an upper surface of the silicon layer. A through-hole passing through the silicon layer and the silicon dioxide layer is formed. The through-hole has an opening which opens at the silicon dioxide layer and is adapted to capture the test cell. The thermally-oxidized film is provided on an inner wall surface of the through-hole, and unified with the silicon dioxide layer at the opening of the through-hole. This cellular electrophysiology sensor chip can stably capture the test cell and provides a gigaseal stably even if test cells have different properties.
摘要翻译：细胞电生理学传感器适于测量测试电池的电气变化。用于传感器的芯片包括隔膜以及在隔膜上主要含有二氧化硅的热氧化膜。隔膜在硅层的上表面上包括硅层和二氧化硅层。形成穿过硅层和二氧化硅层的通孔。通孔具有在二氧化硅层处开口并且适于捕获测试电池的开口。热氧化膜设置在通孔的内壁表面上，并且在通孔的开口处与二氧化硅层一体化。这种细胞电生理学传感器芯片可以稳定地捕获测试细胞，并且即使测试细胞具有不同的性质也能稳定地提供gigaseal。

3. 发明授权

US08816450B2 Fibrous projections structure 有权
标题翻译：纤维投影结构
公开(公告)号：US08816450B2
公开(公告)日：2014-08-26
申请号：US13651103
申请日：2012-10-12
申请人： Panasonic Corporation
发明人： Masaya Nakatani , Hiroshi Ushio , Soichiro Hiraoka , Akiyoshi Oshima , Makoto Takahashi
IPC分类号： H01L27/14 , H01L29/82 , H01L29/84
CPC分类号： G01N33/48728 , B81B2201/0214 , B81B2201/052 , B81C1/00206 , Y10T428/23943
摘要： A silicon structure of the present invention is provided with a silicon substrate (1) to become a base, and a plurality of fibrous projections (2) made of silicon dioxide and directly joined to a silicon-made surface (1a) of the silicon substrate (1). By arbitrarily constructing an area where these fibrous projections (2) are formed in a predetermined area, it is possible to render the area to have at least either hydrophilicity or water retentivity, so as to provide a silicon structure useful for a variety of devices.
摘要翻译：本发明的硅结构设置有成为基底的硅基板（1）和由二氧化硅制成的直接接合到硅基板的硅制表面（1a）的多个纤维突起（2）（1）。通过任意构造这些纤维状突起（2）形成在预定区域的区域，可以使该区域具有至少亲水性或保水性，以提供可用于各种装置的硅结构。

4. 发明授权

US09128056B2 Sample holding carrier, and fluorescence detection system and fluorescence detection device that use same 有权
标题翻译：样品保持载体，荧光检测系统和荧光检测装置使用相同
公开(公告)号：US09128056B2
公开(公告)日：2015-09-08
申请号：US14498877
申请日：2014-09-26
申请人： PANASONIC CORPORATION , SANYO Electric Co., Ltd.
发明人： Yoshiyuki Matsumura , Kenji Nagatomi , Masaya Nakatani , Akio Oki , Morio Nakatani , Takuya Hayashi , Masaaki Hayama
IPC分类号： G01J1/58 , G01N21/64 , G01N21/03 , G01N35/00 , G11B7/00 , G11B7/09 , B01L3/00
CPC分类号： G01N21/645 , B01L3/5085 , B01L2300/024 , B01L2300/0654 , B01L2300/0803 , B01L2300/0806 , B01L2300/0819 , B01L2300/0893 , B01L2300/168 , G01N21/03 , G01N21/6447 , G01N21/6452 , G01N35/00069 , G01N2021/6463 , G01N2021/6482 , G01N2201/105 , G11B7/00 , G11B7/09
摘要： The present invention provides a sample holding carrier that can accurately measure a sample with a simple configuration, and a fluorescence detection system and device that use the same. Biosensor substrate includes: base substrate on which excitation light is incident from a lower surface; reflecting film that is arranged on an upper surface of base substrate to partially reflect the excitation light; and plural wells that are arranged on an upper surface side of reflecting film and have bottom surface portions. The excitation light is converged to be incident on base substrate. Distance from reflecting surface that is of a boundary between reflecting film and base substrate to bottom surface portion of well is less than or equal to a focal depth of the excitation light. Therefore, the sample accommodated in bottom surface portion of well can surely and efficiently be irradiated with the excitation light, and accurately be measured.
摘要翻译：本发明提供一种能够以简单的结构准确测量样品的样品保持载体和使用其的荧光检测系统和装置。生物传感器基板包括：激发光从其下表面入射的基底基板; 反射膜，其布置在基底基板的上表面上以部分地反射激发光; 以及布置在反射膜的上表面侧并具有底表面部分的多个阱。激发光会聚到入射到基底基板上。与反射膜和基底之间的边界的反射面与孔的底面部的距离小于或等于激发光的焦深。因此，能够可靠且有效地利用激发光照射容纳在井底部的样品，并且可以精确地测量。

5. 发明授权

US10247608B2 Spectroscopic module control method 有权
公开(公告)号：US10247608B2
公开(公告)日：2019-04-02
申请号：US15559435
申请日：2016-04-26
申请人： Panasonic Corporation
发明人： Soichiro Hiraoka , Masaya Nakatani
IPC分类号： G01J3/45 , G01J3/26 , G01N21/01 , G02B26/00 , G01J3/02 , G01J3/10 , G01J3/12
摘要： A method of controlling a spectroscopic module that includes a measurement light source, a variable-wavelength optical filter, a photodiode, and a conversion circuit for converting a drive signal voltage into a gap displacement amount. The spectroscopic module has a reference light source for emitting a reference light beam of a known wavelength. The controlling method involves varying a gap for the incident reference light beam, extracting two maximum points among data output from the photodiode, and updating a first conversion formula provided in the conversion circuit through use of drive signal voltages and gap amounts corresponding to the two points.

6. 发明授权

US11262324B2 Gas sensor 有权
公开(公告)号：US11262324B2
公开(公告)日：2022-03-01
申请号：US16603136
申请日：2018-03-28
申请人： PANASONIC CORPORATION
发明人： Atsuo Nakao , Masaya Nakatani , Kiyoshi Toko , Rui Yatabe , Bartosz Wyszynski
IPC分类号： G01N27/12 , H01G2/00 , B82Y5/00
摘要： A gas sensor includes: a substrate; a first conductor and a second conductor that are disposed on the substrate; an insulating layer; and an adsorbent layer. The insulating layer covers the first conductor and the second conductor, and has a first opening that allows a part of a surface of the first conductor to be exposed therethrough and a second opening that allows a part of a surface of the second conductor to be exposed therethrough. The adsorbent layer contains a conductive material and an organic adsorbent that can adsorb a gas. The adsorbent layer is in contact with the first conductor and the second conductor respectively through the first opening and the second opening.

7. 发明授权

US09500589B2 Sample holding carrier and fluorescence detection device using same 有权
标题翻译：样品保持载体和使用其的荧光检测装置
公开(公告)号：US09500589B2
公开(公告)日：2016-11-22
申请号：US14514048
申请日：2014-10-14
申请人： PANASONIC CORPORATION , SANYO ELECTRIC CO., LTD.
发明人： Morio Nakatani , Masaya Nakatani , Yoshiyuki Matsumura , Kenji Nagatomi , Akio Oki
IPC分类号： G01N21/64 , G01N21/27
CPC分类号： G01N21/6452 , G01N21/274 , G01N21/6428 , G01N21/645 , G01N21/6486 , G01N2021/6439
摘要： Disclosed is a sample holding carrier allowing samples to be measured accurately, and a fluorescence detection device for use with the sample holding carrier. A biosensor substrate includes a base substrate, a plurality of wells formed on a first surface side of the base substrate; and grooves formed on the first surface side of the base substrate separately from the wells and generating fluorescence under exposure to excitation light. The fluorescence detection device applies excitation light to the grooves, thereby figuring out the level of the fluorescence to be detected from the biosensor substrate. As a result, the fluorescence detection device can amplify the detection signals of the fluorescence generated when the excitation light is applied to the wells to an appropriate level, thereby accurately detecting the fluorescence generated in the samples.
摘要翻译：公开了一种允许准确测量样品的样品保持载体和用于样品保持载体的荧光检测装置。生物传感器基板包括基底基板，形成在基底基板的第一表面侧上的多个阱; 以及与所述孔分开形成在所述基底基板的第一表面侧上的凹槽，并且在暴露于激发光的情况下产生荧光。荧光检测装置将激发光施加到沟槽，从而从生物传感器基板上确定要检测的荧光的水平。结果，荧光检测装置可以将激发光施加到阱上产生的荧光的检测信号放大到适当的水平，从而准确地检测样品中产生的荧光。

8. 发明授权

US11740197B2 Gas sensor 有权
公开(公告)号：US11740197B2
公开(公告)日：2023-08-29
申请号：US17541843
申请日：2021-12-03
申请人： PANASONIC CORPORATION
发明人： Atsuo Nakao , Masaya Nakatani , Kiyoshi Toko , Rui Yatabe , Bartosz Wyszynski
IPC分类号： G01N27/12 , G01N35/08 , G01R21/06
CPC分类号： G01N27/12
摘要： A gas sensor includes: a substrate; a first conductor and a second conductor that are disposed on the substrate; an insulating layer; and an adsorbent layer. The insulating layer covers the first conductor and the second conductor, and has a first opening that allows a part of a surface of the first conductor to be exposed therethrough and a second opening that allows a part of a surface of the second conductor to be exposed therethrough. The adsorbent layer contains a conductive material and an organic adsorbent that can adsorb a gas. The adsorbent layer is in contact with the first conductor and the second conductor respectively through the first opening and the second opening.

9. 发明授权

US10408715B2 Adsorption pump 有权
公开(公告)号：US10408715B2
公开(公告)日：2019-09-10
申请号：US15554225
申请日：2016-03-25
申请人： Panasonic Corporation
发明人： Yuji Murashima , Masaya Nakatani , Atsuo Nakao
IPC分类号： G01N1/22 , G01N1/40 , G01N30/08 , G01N30/80 , G01N1/24 , G01N30/84
摘要： An adsorption pump includes a housing, a movable part, and an adsorption part. The housing has inlet and outlet ports for a sample. The movable part is at least partly located inside the housing. The adsorption part is located inside the housing.

10. 发明授权

US09046490B2 Fluorescence detection device 有权
标题翻译：荧光检测装置
公开(公告)号：US09046490B2
公开(公告)日：2015-06-02
申请号：US14498596
申请日：2014-09-26
申请人： PANASONIC CORPORATION , SANYO Electric Co., Ltd.
发明人： Kenji Nagatomi , Masaya Nakatani
IPC分类号： G01N21/64
CPC分类号： G01N21/6486 , G01N21/645 , G01N21/6452 , G01N2021/6463
摘要： To provide a fluorescence detection device that can effectively remove autofluorescence using a simple configuration. A fluorescence detection device comprises: semiconductor laser for emitting excitation light; an objective lens for converging excitation light onto a sample on a biosensor substrate; an anamorphic lens which introduces astigmatism to fluorescence that is from the biosensor substrate and incident on the objective lens and that passed through the objective lens; a spectral element for separating the fluorescence into a plurality of light rays; and a fluorescence detector for receiving the light rays separated by the spectral element. On the light receiving surface of the fluorescence detector, the spectral element splits the fluorescence so that the fluorescence generated at the sample is separated from the fluorescence generated at a specific depth position other than the sample position.
摘要翻译：提供可以使用简单配置有效去除自体荧光的荧光检测装置。荧光检测装置包括：用于发射激发光的半导体激光器; 用于将激发光会聚到生物传感器基板上的样品上的物镜; 一种变形透镜，其对来自生物传感器基板的荧光引入散光，并入射到物镜上并穿过物镜; 用于将荧光分离成多个光线的光谱元件; 以及用于接收由光谱元件分离的光线的荧光检测器。在荧光检测器的光接收表面上，光谱元件分离荧光，使得在样品处产生的荧光与在样品位置以外的特定深度位置处产生的荧光分离。

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