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1. 发明授权

US4954318A Optical sensor 失效
标题翻译：光学传感器
公开(公告)号：US4954318A
公开(公告)日：1990-09-04
申请号：US91432
申请日：1987-08-31
申请人： Masao Yafuso , Cheng F. Yan , Thomas G. Hacker , Henry K. Hui , Thomas P. Maxwell , William W. Miller
发明人： Masao Yafuso , Cheng F. Yan , Thomas G. Hacker , Henry K. Hui , Thomas P. Maxwell , William W. Miller
IPC分类号： G01N21/77
CPC分类号： G01N21/7703 , G01N2021/772
摘要： An apparatus for measuring the concentration of a component in a medium comprising:an optical sensor including at least one optical indicator for providing an optical signal which varies in response to the presence of a component in a medium;an optical signal fiber capable of transmitting the optical signal from the optical sensor; anda supply reservoir associated with the optical sensor and acting to provide additional optical indicator to the optical sensor.
摘要翻译：一种用于测量介质中的组分的浓度的装置，包括：光学传感器，包括至少一个光学指示器，用于提供响应于介质中组分的存在而变化的光学信号; 能够从光学传感器发送光信号的光信号光纤; 以及与所述光学传感器相关联并用于向所述光学传感器提供附加光学指示器的供应储存器。

2. 发明授权

US5120510A Sensor and method for sensing the concentration of a component in a medium 失效
标题翻译：用于感测介质中组分浓度的传感器和方法
公开(公告)号：US5120510A
公开(公告)日：1992-06-09
申请号：US624200
申请日：1990-12-06
申请人： Ted H. Gourley , Thomas P. Maxwell , Thomas G. Hacker , William W. Miller , Masao Yafuso
发明人： Ted H. Gourley , Thomas P. Maxwell , Thomas G. Hacker , William W. Miller , Masao Yafuso
IPC分类号： A61B5/00 , G01N21/64 , G01N21/77 , G01N21/80 , G01N21/81 , G01N31/22
CPC分类号： G01N21/7703 , A61B5/1459 , G01N31/223 , G01N2021/6434 , G01N2021/6439 , G01N2021/772 , G01N2021/773 , G01N2021/7786 , G01N21/80 , G01N21/81
摘要： An apparatus for sensing the concentration of a component such as oxygen in a medium such as blood. The apparatus includes an elongated signal transmitter and a sensing element at one end thereof. A substantially rigid sleeve is secured around such end to provide a pocket for the sensing element.
摘要翻译：用于感测诸如血液的介质中诸如氧的组分的浓度的装置。该装置包括细长的信号发射器和在其一端的感测元件。围绕该端部固定有基本刚性的套筒，以提供感测元件的口袋。

3. 发明授权

US5006314A Sensor and method for sensing the concentration of a component in a medium 失效
标题翻译：用于感测介质中组分浓度的传感器和方法
公开(公告)号：US5006314A
公开(公告)日：1991-04-09
申请号：US206189
申请日：1988-06-13
申请人： Ted H. Gourley , Thomas P. Maxwell , Thomas G. Hacker , William W. Miller , Masao Yafuso
发明人： Ted H. Gourley , Thomas P. Maxwell , Thomas G. Hacker , William W. Miller , Masao Yafuso
IPC分类号： A61B5/00 , G01N21/64 , G01N21/80 , G01N21/81 , G01N31/22
CPC分类号： G01N21/7703 , A61B5/1459 , G01N31/223 , G01N2021/6434 , G01N2021/6439 , G01N2021/772 , G01N2021/773 , G01N2021/7786 , G01N21/80 , G01N21/81
摘要： An apparatus for sensing the concentration of a component such as oxygen in a medium such as blood. The apparatus includes an elongated signal transmitter and a sensing element at one end thereof. A substantially rigid sleeve is secured around such end to provide a pocket for the sensing element.
摘要翻译：用于感测诸如血液的介质中诸如氧的组分的浓度的装置。该装置包括细长的信号发射器和在其一端的感测元件。围绕该端部固定有基本刚性的套筒，以提供感测元件的口袋。

4. 发明授权

US5284775A Gas sensing element and method for making same 失效
标题翻译：气体传感元件及其制造方法
公开(公告)号：US5284775A
公开(公告)日：1994-02-08
申请号：US949771
申请日：1992-09-21
申请人： Masao Yafuso , Mark Z. Holody , Thomas P. Maxwell , Thomas G. Hacker
发明人： Masao Yafuso , Mark Z. Holody , Thomas P. Maxwell , Thomas G. Hacker
IPC分类号： G01N21/64 , G01N21/77 , G01N21/78 , G01N31/22 , G01N33/49 , G01N33/50
CPC分类号： G01N21/783 , G01N31/223 , Y10T436/204998
摘要： Sensing composition precursors and sensing compositions, useful in sensing the concentration of a gas, e.g., carbon dioxide, in a medium, e.g., blood, are disclosed. In one embodiment, the sensing composition precursor comprises a dispersed aqueous liquid including a sensing component dissolved therein, a polymer precursor, and a hydrophilic dispersing agent selected from hydroxyalkyl celluloses and mixtures thereof in an amount effective to facilitate maintaining the dispersed aqueous liquid.
摘要翻译：公开了感测组合物前体和感测组合物，其可用于感测介质（例如血液）中的二氧化碳气体的浓度。在一个实施方案中，感测组合物前体包含分散的水性液体，其包含溶解于其中的感测组分，聚合物前体和选自羟烷基纤维素及其混合物的亲水性分散剂，其量有助于维持分散的水性液体。

5. 发明授权

US5175016A Method for making gas sensing element 失效
标题翻译：制造气体传感元件的方法
公开(公告)号：US5175016A
公开(公告)日：1992-12-29
申请号：US496560
申请日：1990-03-20
申请人： Masao Yafuso , Mark Z. Holody , Thomas P. Maxwell , Thomas G. Hacker
发明人： Masao Yafuso , Mark Z. Holody , Thomas P. Maxwell , Thomas G. Hacker
IPC分类号： G01N21/64 , G01N21/77 , G01N21/78 , G01N31/22 , G01N33/49
CPC分类号： G01N21/783 , G01N31/223 , Y10T436/204998
摘要： A method for making a sensing element, and an assembled sensing element, useful in sensing the concentration of a gas, e.g., carbon dioxide, in a medium, e. g. blood, are disclosed. In one embodiment, the method comprises placing a quantity of a sensing composition precursor between and in contact with a transparent, gas impermeable solid disc and an opaque, gas permeable film, the sensing composition precursor comprises a sensing component, a polymer precursor and a cross-linking agent; and forming a gas sensing composition from this quantity of sensing composition precursor.

6. 外观设计

USD326718S Blood sensor cassette 失效
公开(公告)号：USD326718S
公开(公告)日：1992-06-02
申请号：US456261
申请日：1989-12-26
申请人： Thomas P. Maxwell , Charles M. Kienholz , Thomas G. Hacker
设计人： Thomas P. Maxwell , Charles M. Kienholz , Thomas G. Hacker

7. 发明授权

US5057278A Sterile loop calibration system 失效
标题翻译： STERILE LOOP CALIBRATION系统
公开(公告)号：US5057278A
公开(公告)日：1991-10-15
申请号：US514704
申请日：1990-04-26
申请人： Thomas P. Maxwell , Thomas G. Hacker
发明人： Thomas P. Maxwell , Thomas G. Hacker
IPC分类号： A61B5/145 , A61B5/00 , B01F5/06 , C12M1/34 , G01N27/26 , G01N27/416
CPC分类号： B01F5/0691 , A61B5/1495 , G01N27/4163 , G01N27/4165 , Y10S128/12 , Y10S128/13 , Y10T436/10 , Y10T436/102499
摘要： An endless path calibration system comprising a sensor cassette having a flow-through passage and at least one sensor to be calibrated, a chamber coupled to the sensor cassette to define an endless path and a sterile calibration liquid in the endless path. A gas injection passage for injecting gas into the sterile calibration liquid and a gas vent leading from the endless path to the exterior of the endless path. A check valve allows gas to escape from the endless path and substantially prevents gas and liquid from entering the endless path through the gas vent.

8. 发明授权

US5462052A Apparatus and method for use in measuring a compositional parameter of blood 失效
标题翻译：用于测量血液成分参数的装置和方法
公开(公告)号：US5462052A
公开(公告)日：1995-10-31
申请号：US55800
申请日：1993-04-27
申请人： John L. Gehrich , Thomas P. Maxwell , Thomas G. Hacker , Mark Z. Holody
发明人： John L. Gehrich , Thomas P. Maxwell , Thomas G. Hacker , Mark Z. Holody
IPC分类号： A61B5/00 , A61B5/0215
CPC分类号： A61B5/02158 , A61B5/1459
摘要： A sensor cassette for use in measuring a compositional parameter of blood comprising a housing having a wall defining a passage which is adapted to receive blood. The wall is at least somewhat permeable to the compositional parameter. A support element, which is less permeable to the compositional parameter of blood than the housing, is carried by a region of the wall. A sensor is carried by the support element and provides a signal in response to the compositional parameter. The support element separates the sensor from at least a portion of such region of the wall so that the affect of the permeability of the housing to the compositional parameter on the signal from the sensor is reduced.
摘要翻译：一种用于测量血液成分参数的传感器盒，包括具有限定通道的壁的外壳，所述通道适于接收血液。墙壁对组成参数至少有一定的渗透性。对于血液的组成参数对外壳的渗透性较小的支撑元件由壁的区域承载。传感器由支撑元件承载并响应于组成参数提供信号。支撑元件将传感器与壁的这种区域的至少一部分分开，使得壳体的渗透性对来自传感器的信号的组成参数的影响减小。

9. 发明授权

US5171029A Seal construction for pump apparatus 失效
标题翻译：泵装置的密封结构
公开(公告)号：US5171029A
公开(公告)日：1992-12-15
申请号：US747533
申请日：1991-08-20
申请人： Thomas P. Maxwell , Thomas G. Hacker
发明人： Thomas P. Maxwell , Thomas G. Hacker
IPC分类号： A61B5/00 , G01N27/416
CPC分类号： A61B5/1495 , G01N27/4163 , G01N27/4165 , Y10S128/12 , Y10S128/13 , Y10T436/10 , Y10T436/102499
摘要： An endless path calibration system comprising a sensor cassette having a flow-through passage and at least one sensor to be calibrated, a chamber coupled to the sensor cassette to define an endless path and a sterile calibration liquid in the endless path. A gas injection passage for injecting gas into the sterile calibration liquid and a gas vent leading from the endless path to the exterior of the endless path. A check valve allows gas to escape from the endless path and substantially prevents gas and liquid from entering the endless path through the gas vent.
摘要翻译：一种无限路径校准系统，包括具有流通通道和至少一个要校准的传感器的传感器盒，耦合到传感器盒以在环形路径中限定无尽路径和无菌校准液体的腔室。用于将气体注入到无菌校准液体中的气体注入通道和从环形路径引导到环形路径的外部的气体通道。止回阀允许气体从环形路径逸出，并且基本上防止气体和液体通过排气口进入循环路径。

10. 发明授权

US4951669A Blood parameter measurement system 失效
标题翻译：血液参数测量系统
公开(公告)号：US4951669A
公开(公告)日：1990-08-28
申请号：US229703
申请日：1988-08-08
申请人： Thomas P. Maxwell , Thomas G. Hacker
发明人： Thomas P. Maxwell , Thomas G. Hacker
IPC分类号： A61B5/145 , A61B5/00 , A61B5/1459 , A61M25/00
CPC分类号： A61B5/1459
摘要： A parameter of blood is sensed with a system which includes a catheter and a sensor and a volume oscillator element. The catheter has a lumen extending therethrough, a proximal end, a distal end and an opening, adapted to be placed in the blood vessel of a patient. The sensor senses a blood parameter and is adapted to be located outside the patient's body in fluid communication with the lumen. The volume oscillator element is in fluid communication with the lumen and is capable of acting to periodically cause blood to enter and exit the lumen. The system is structured so that a flush or anti-clotting solution flows into the patient when the volume oscillator element is inactive. With the volume oscillator activated, blood is moved back and forth in the lumen to expose the sensors to blood so that the blood parameter of interest can be sensed.
摘要翻译：用包括导管和传感器以及体积振荡器元件的系统检测血液的参数。导管具有延伸穿过其中的内腔，近端，远端和开口，适于放置在患者的血管中。传感器感测血液参数，并且适于位于患者身体外部与流体流体连通。体积振荡器元件与内腔流体连通，并且能够作用以周期性地使血液进入和离开管腔。该系统的结构使得当体积振荡器元件不活动时，冲洗或抗凝血溶液流入患者体内。当体积振荡器激活时，血液在内腔中来回移动以将传感器暴露于血液，使得可以感测感兴趣的血液参数。

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